Carsten Geisler

Carsten Geisler

Professor

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    ORCID: 0000-0002-8472-0771

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    1. Published

      Regulation and function of the CD3¿ DxxxLL motif: a binding site for adaptor protein-1 and adaptor protein-2 in vitro

      Dietrich, J., Kastrup, J., Nielsen, B. L., Odum, N. & Geisler, Carsten, 1997, In: Journal of Cell Biology. 138, 2, p. 271-81 10 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    2. Published

      Ligand-induced TCR down-regulation is not dependent on constitutive TCR cycling

      Dietrich, J., Bonefeld, Charlotte Menne, Lauritsen, J. P. H., von Essen, Marina Rode, Rasmussen, B. A., Ødum, Niels & Geisler, Carsten, 2002, In: Journal of Immunology. 168, 11, p. 5434-40 6 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    3. Published

      T cell activation. II. Activation of human T lymphoma cells by cross-linking of their MHC class I antigens

      Dissing, Steen, Geisler, Carsten, Rubin, B., Plesner, T. & Claesson, Mogens Helweg, 1990, In: Cellular Immunology. 126, 1, p. 196-210 14 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    4. Published

      CD4(+) T cells producing interleukin (IL)-17, IL-22 and interferon-? are major effector T cells in nickel allergy

      Dyring Andersen, B., Skov, Lone, Løvendorf, M. B., Bzorek, M., Søndergaard, K., Lauritsen, J. H., Dabelsteen, Sally, Geisler, Carsten & Bonefeld, Charlotte Menne, 2013, In: Contact Dermatitis. 68, 6, p. 339-347 9 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    5. Published

      Increased number and frequency of group 3 innate lymphoid cells in nonlesional psoriatic skin

      Dyring-Andersen, Beatrice, Geisler, Carsten, Agerbeck, C., Lauritsen, J. P. H., Gúdjonsdottir, S. D., Skov, L. & Bonefeld, Charlotte Menne, Mar 2014, In: British Journal of Dermatology. 170, 3, p. 609-16 8 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    6. Published

      The Vitamin D Analogue Calcipotriol Reduces the Frequency of CD8+IL-17+ T Cells in Psoriasis Lesions

      Dyring-Andersen, Beatrice, Bonefeld, Charlotte Menne, Bzorek, M., Løvendorf, M. B., Lauritsen, J. P. H., Skov, Lone & Geisler, Carsten, Jul 2015, In: Scandinavian Journal of Immunology. 82, 1, p. 84-91 8 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    7. Published

      IL-17A- and IFNγ-Producing T Cells in Healthy Skin

      Dyring-Andersen, Beatrice, Nielsen, M. M., Geisler, Carsten, Bonefeld, Charlotte Menne & Skov, L., Apr 2016, In: Scandinavian Journal of Immunology. 83, 4, p. 297-299 3 p.

      Research output: Contribution to journal › Comment/debate › Research

    8. Published

      CD4(+) T cells producing interleukin (IL)-17, IL-22 and interferon-γ are major effector T cells in nickel allergy

      Dyring-Andersen, Beatrice, Skov, Lone, Løvendorf, M. B., Bzorek, M., Søndergaard, K., Lauritsen, J. H., Dabelsteen, Sally, Geisler, Carsten & Bonefeld, Charlotte Menne, Jun 2013, In: Contact Dermatitis. Supplement. 68, 6, p. 339-47 9 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    9. Published

      Constitutive STAT3-activation in Sezary syndrome: tyrphostin AG490 inhibits STAT3-activation, interleukin-2 receptor expression and growth of leukemic Sezary cells

      Eriksen, K. W., Kaltoft, K., Mikkelsen, G., Nielsen, M., Zhang, Q., Geisler, Carsten, Nissen, M. H., Röpke, C., Wasik, M. A. & Odum, N., 2001, In: Leukemia. 15, 5, p. 787-93 6 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    10. Published

      The combination of IL-21 and IFN-alpha boosts STAT3 activation, cytotoxicity and experimental tumor therapy

      Eriksen, K. W., Søndergaard, H., Woetmann, Anders , Krejsgaard, T., Skak, K., Geisler, Carsten, Wasik, M. A. & Odum, N., 2008, In: Molecular Immunology. 46, 5, p. 812-20 8 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    11. Published

      Deficient SOCS3 and SHP-1 Expression in Psoriatic T Cells

      Eriksen, K. W., Woetmann, Anders , Skov, Lone, Krejsgaard, T., Bovin, L. F., Hansen, M. L., Grønbæk, Kirsten, Billestrup, Nils, Nissen, Mogens Holst, Geisler, Carsten, Wasik, M. A. & Ødum, Niels, 2010, In: Journal of Investigative Dermatology. 130, 6, p. 1590-7 8 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    12. Published

      Increased sensitivity to interferon-alpha in psoriatic T cells

      Eriksen, K. W., Lovato, P., Skov, Lone, Krejsgaard, T., Kaltoft, K., Geisler, Carsten & Ødum, Niels, 2005, In: Journal of Investigative Dermatology. 125, 5, p. 936-44 8 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    13. Published

      Bi-phasic effect of interferon (IFN)-alpha: IFN-alpha up- and down-regulates interleukin-4 signaling in human T cells

      Eriksen, K. W., Sommer, V. H., Woetmann, Anders , Rasmussen, A. B., Brender, C., Svejgaard, A., Skov, Søren, Geisler, Carsten & Ødum, Niels, 2003, In: Journal of Biological Chemistry. 279, 1, p. 169-76 7 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    14. Published

      Interleukin-15-activated natural killer cells kill autologous osteoclasts via LFA-1, DNAM-1 and TRAIL, and inhibit osteoclast-mediated bone erosion in vitro

      Feng, S., Madsen, S. H., Viller, N. N., Neutzsky-Wulff, A. V., Geisler, Carsten, Karlsson, L. & Söderström, K., Jul 2015, In: Immunology. 145, 3, p. 367-79 13 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    15. Published

      In vitro differentiated human CD4+ T cells produce hepatocyte growth factor

      Ford, Shayne Lavondua, Buus, Terkild Brink, Nastasi, C., Geisler, Carsten, Bonefeld, Charlotte Menne, Ødum, Niels & Woetmann, Anders , 2023, In: Frontiers in Immunology. 14, 1210836.

      Research output: Contribution to journal › Journal article › Research › peer-review

    16. Published

      The Expression of IL-21 Is Promoted by MEKK4 in Malignant T Cells and Associated with Increased Progression Risk in Cutaneous T-Cell Lymphoma

      Fredholm, S., Litvinov, I. V., Mongan, N. P., Schiele, S., Willerslev-Olsen, A., Petersen, D. L., Krejsgaard, T., Sibbesen, N., Nastasi, C., Bonefeld, Charlotte Menne, Persson, J. L., thor Straten, E. P., Andersen, Mads Hald, Koralov, S. B., Wasik, M. M., Geisler, Carsten, Sasseville, D., Woetmann, Anders & Ødum, Niels, 2016, In: Journal of Investigative Dermatology. 136, 4, p. 866-869 4 p.

      Research output: Contribution to journal › Comment/debate › Research › peer-review

    17. Published

      STAT3 activation and infiltration of eosinophil granulocytes in mycosis fungoides

      Fredholm, S., Gjerdrum, Lise Mette Rahbek, Willerslev-Olsen, A., Petersen, D. L., Nielsen, I. Ø., Kauczok, C., Wobser, M., Ralfkiaer, U., Bonefeld, Charlotte Menne, Wasik, M. A., Krejsgaard, T., Geisler, Carsten, Ralfkiaer, E., Gniadecki, R., Woetmann, Anders & Ødum, Niels, 2014, In: Anticancer Research. 34, 10, p. 5277-5286 10 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    18. Published

      SATB1 in malignant T cells

      Fredholm, S. M., Willerslev-Olsen, A., Met, Ö., Kubat, L., Gluud, M., Mathiasen, S. L., Friese, C., Blümel, E., Petersen, D. L., Hu, T., Nastasi, C., Lindahl, L. M., Buus, T. B., Krejsgaard, T. F., Wasik, M. A., Kopp, K. L. M., Koralov, S. B., Persson, J. L., Bonefeld, C. M., Geisler, C. & 4 others, Woetmann, Anders , Iversen, L., Becker, J. C. & Ødum, Niels, 2018, In: The Journal of Investigative Dermatology. 138, 8, p. 1805-1815 11 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    19. Published

      Neutrophil infiltration in allergic contact dermatitis to nickel

      Funch, Anders Boutrup, Ahlström, M. G., Johansen, Jeanne Duus, Geisler, Carsten & Bonefeld, Charlotte Menne, 2024, In: British Journal of Dermatology. 190, 4, p. 569-570 2 p.

      Research output: Contribution to journal › Comment/debate › Research › peer-review

    20. Published

      CD8+ tissue-resident memory T cells recruit neutrophils that are essential for flare-ups in contact dermatitis

      Funch, Anders Boutrup, Mraz, Veronika, Gadsbøll, A. S. Ø., Jee, Mia Hamilton, Weber, Julie Friis, Ødum, Niels, Woetmann, Anders , Johansen, Jeanne Duus, Geisler, Carsten & Bonefeld, Charlotte Menne, 2022, In: Allergy: European Journal of Allergy and Clinical Immunology. 77, 2, p. 513-524

      Research output: Contribution to journal › Journal article › Research › peer-review

    21. Published

      CD4+ T cells inhibit the generation of CD8+ epidermal-resident memory T cells directed against clinically relevant contact allergens

      Funch, Anders Boutrup, Weber, Julie Friis, Lohmann, R. K. D., Mraz, Veronika, Yeung, Kelvin, Jee, Mia Hamilton, Ødum, Niels, Woetmann, Anders , Johansen, Jeanne Duus, Geisler, Carsten & Bonefeld, Charlotte Menne, 2023, In: Contact Dermatitis. 88, 6, p. 425-437

      Research output: Contribution to journal › Journal article › Research › peer-review

    22. Published

      Epidermal T cell subsets—Effect of age and antigen exposure in humans and mice

      Gadsbøll, A. S. Ø., Jee, Mia Hamilton, Ahlström, M. G., Dyring-Andersen, Beatrice, Woetmann, Anders , Ødum, Niels, Johansen, Jeanne Duus, Geisler, Carsten & Bonefeld, Charlotte Menne, 2021, In: Contact Dermatitis. 84, 6, p. 375-384

      Research output: Contribution to journal › Journal article › Research › peer-review

    23. Published

      The role of the different CD3γ domains in TCR expression and signaling

      Garcillán, B., Megino, R. F., Herrero-Alonso, M., Guardo, A. C., Perez-Flores, V., Juraske, C., Idstein, V., Martin-Fernandez, J. M., Geisler, Carsten, Schamel, W. W. A., Marin, A. V. & Regueiro, J. R., 2022, In: Frontiers in Immunology. 13, 978658.

      Research output: Contribution to journal › Journal article › Research › peer-review

    24. Published

      Transmembrane signalling via HLA-DR molecules on T cells from a Sezary T-cell leukaemia line

      Geisler, Carsten, Kuhlmann, J., Møller, T., Plesner, T. & Rubin, B., 1990, In: Scandinavian Journal of Immunology. 32, 6, p. 731-5 4 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    25. Published

      The T cell receptor. Structural and functional studies

      Geisler, Carsten, 1995, In: Danish Medical Bulletin. 42, 4, p. 342-57 15 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    26. Published

      Failure to synthesize the human T-cell CD3-zeta chain and its consequence for the T-cell receptor-CD3 complex expression

      Geisler, Carsten, Kuhlmann, J., Plesner, T. & Rubin, B., 1989, In: Scandinavian Journal of Immunology. 30, 2, p. 191-7 6 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    27. Published

      Association of the human CD3-zeta chain with the alpha beta-T cell receptor/CD3 complex. Clues from a T cell variant with a mutated T cell receptor-alpha chain

      Geisler, Carsten, Schøller, J., Wahi, M. A., Rubin, B. & Weiss, A., 1990, In: Journal of Immunology. 145, 6, p. 1761-7 6 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    28. Published

      Characterization and expression of the human T cell receptor-T3 complex by monoclonal antibody F101.01

      Geisler, Carsten, Plesner, T., Pallesen, G., Skjødt, K., Ødum, Niels & Larsen, J. K., 1988, In: Scandinavian Journal of Immunology. 27, 6, p. 685-96 11 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    29. Published

      Specific depletion of mature T lymphocytes from human bone marrow

      Geisler, Carsten, Møller, J., Plesner, T., Dickmeiss, E., Pallesen, G., Larsen, J. K., Jacobsen, N. & Svejgaard, A., 1989, In: Scandinavian Journal of Immunology. 29, 5, p. 617-25 8 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    30. Published

      Leucine-based receptor sorting motifs are dependent on the spacing relative to the plasma membrane

      Geisler, Carsten, Dietrich, J., Nielsen, B. L., Kastrup, J., Lauritsen, J. P. H., Ødum, Niels & Bartels, Mette Damkjær, 1998, In: Journal of Biological Chemistry. 273, 33, p. 21316-23 7 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    31. Published

      Monocyte functions in diabetes mellitus

      Geisler, Carsten, Almdal, Thomas Peter, Bennedsen, J., Rhodes, J. M. & Kølendorf, K., 1982, In: APMIS : Acta pathologica, microbiologica et immunologica Scandinavica. Supplementum. 90, 1, p. 33-7 4 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    32. Published

      Failure to synthesize the CD3-gamma chain. Consequences for T cell antigen receptor assembly, processing, and expression

      Geisler, Carsten, 1992, In: Journal of Immunology. 148, 8, p. 2437-45 8 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    33. Published

      Structural mutations of C-domains in members of the Ig superfamily. Consequences for the interactions between the T cell antigen receptor and the zeta 2 homodimer

      Geisler, Carsten, Rubin, B., Caspar-Bauguil, S., Champagne, E., Vangsted, A., Hou, X. & Gajhede, Michael, 1992, In: Journal of Immunology. 148, 11, p. 3469-77 8 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    34. Published

      Cholestatic hepatitis during treatment with mexiletine/lidocaine

      Geisler, Carsten & Keiding, S., 1984, In: Ugeskrift for læger. 146, 16, p. 1212-3 1 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    35. Published

      An enzyme-linked immunosorbent assay for autoantibodies against the nuclear protein Scl-70

      Geisler, Carsten & Høier-Madsen, M., 1985, In: Journal of Immunological Methods. 80, 2, p. 211-9 8 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    36. Published

      Novel primary thymic defect with T lymphocytes expressing gamma delta T cell receptor

      Geisler, Carsten, Pallesen, G., Platz, P., Odum, N., Dickmeiss, E., Ryder, L. P., Svejgaard, A., Plesner, T., Larsen, J. K. & Koch, C., 1989, In: Journal of Clinical Pathology. 42, 7, p. 705-11 6 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    37. Published

      Assembly, intracellular processing, and expression at the cell surface of the human alpha beta T cell receptor/CD3 complex. Function of the CD3-zeta chain

      Geisler, Carsten, Kuhlmann, J. & Rubin, B., 1989, In: Journal of Immunology. 143, 12, p. 4069-77 8 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    38. Published

      Identification of alpha beta and gamma delta T cell receptor-positive cells

      Geisler, Carsten, Larsen, J. K. & Plesner, T., 1988, In: Scandinavian Journal of Immunology. 28, 6, p. 741-5 4 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    39. Published

      TCR trafficking in resting and stimulated T cells

      Geisler, Carsten, 2004, In: Critical Reviews in Immunology. 24, 1, p. 67-86 19 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    40. Published

      Reply to control of T cell activation by vitamin

      Geisler, Carsten, Jan 2011, In: Nature Immunology. 12, 1, p. 3-4 2 p.

      Research output: Contribution to journal › Letter › Research › peer-review

    41. Published

      Staphylococcus enterotoxin A modulates interleukin 15-induced signaling and mitogenesis in human T cells

      Gerwien, J., Kaltoft, K., Nielsen, M., Nielsen, M. B., Svejgaard, A., Geisler, Carsten, Röpke, C. & Odum, N., 1998, In: HLA. 51, 2, p. 164-73 9 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    42. Published

      Cutting edge: TCR stimulation by antibody and bacterial superantigen induces Stat3 activation in human T cells

      Gerwien, J., Nielsen, M., Labuda, T., Nissen, M. H., Svejgaard, A., Geisler, Carsten, Röpke, C. & Odum, N., 1999, In: Journal of Immunology. 163, 4, p. 1742-5 3 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    43. Published

      MicroRNAs in the pathogenesis, diagnosis, prognosis and targeted treatment of cutaneous T-cell lymphomas

      Gluud, Maria, Willerslev-Olsen, A., Gjerdrum, Lise Mette Rahbek, Lindahl, L. M., Buus, Terkild Brink, Andersen, Mads Hald, Bonefeld, Charlotte Menne, Krejsgaard, T., Litvinov, I. V., Iversen, L., Becker, J. C., Persson, J. L., Koralov, S. B., Litman, Thomas, Geisler, Carsten, Woetmann, Anders & Ødum, Niels, 2020, In: Cancers. 12, 5, 18 p., 1229.

      Research output: Contribution to journal › Review › Research › peer-review

    44. Published

      MicroRNA-93 Targets p21 and Promotes Proliferation in Mycosis Fungoides T Cells

      Gluud, Maria, Fredholm, S., Blümel, E., Willerslev-Olsen, A., Buus, Terkild Brink, Nastasi, C., Krejsgaard, T., Bonefeld, Charlotte Menne, Woetmann, Anders , Iversen, L., Litman, Thomas, Geisler, Carsten, Ødum, Niels & Lindahl, L. M., 2021, In: Dermatology. 237, p. 277–282

      Research output: Contribution to journal › Journal article › Research › peer-review

    45. Published

      Malignant T cells induce skin barrier defects through cytokine-mediated JAK/STAT signaling in cutaneous T-cell lymphoma

      Gluud, M., Pallesen, E. M. H., Buus, T. B., Gjerdrum, L. M. R., Lindahl, L. M., Kamstrup, M. R., Bzorek, M., Danielsen, M., Bech, R., Monteiro, M. N., Blümel, E., Willerslev-Olsen, A., Lykkebo-Valløe, A., Vadivel, C. K., Krejsgaard, T., Bonefeld, C. M., Geisler, C., Becker, J. C., Koralov, S. B., Iversen, L. & 3 others, Litman, Thomas, Woetmann, Anders & Ødum, Niels, 2023, In: Blood. 141, 2, p. 180-193 14 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    46. Published

      TCR down-regulation boosts T-cell-mediated cytotoxicity and protection against poxvirus infections

      Hansen, A. K., Regner, M., Bonefeld, Charlotte Menne, Boding, L., Kongsbak-Wismann, Martin, Ødum, Niels, Müllbacher, A., Geisler, Carsten & von Essen, Marina Rode, 2011, In: European Journal of Immunology. 41, 7, p. 1948-1957 10 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    47. Published

      IFN-α primes T- and NK-cells for IL-15-mediated signaling and cytotoxicity

      Hansen, M. L., Woetmann, Anders , Krejsgaard, T., Kopp, K. L. M., Søkilde, R., Litman, Thomas, Straten, P. T., Geisler, Carsten, Wasik, M. A., Ødum, Niels & Eriksen, K. W., Sep 2011, In: Molecular Immunology. 48, 15-16, p. 2087-93 7 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    48. Published

      Low SATB1 Expression Promotes IL-5 and IL-9 Expression in Sézary Syndrome

      Herrera, A., Fredholm, S., Cheng, A., Mimitou, E. P., Seffens, A., Bar-Natan, M., Sun, A., Latkowski, J. A., Willerslew-Olsen, A., Buus, T. B., Gluud, M., Krejsgaard, T., Torres-Rusillo, S., Bonefeld, C. M., Woetmann, A., Geisler, C., Geskin, L. J., Ouyang, Z., Smibert, P., Ødum, N. & 1 others, Koralov, S. B., 2020, In: Journal of Investigative Dermatology. 140, 3, p. 713-716 4 p.

      Research output: Contribution to journal › Letter › Research › peer-review

    49. Published

      The cytoplasmic tail of FcgammaRIIIAalpha is involved in signaling by the low affinity receptor for immunoglobulin G

      Hou, X., Dietrich, J. & Geisler, Carsten, 1996, In: Journal of Biological Chemistry. 271, 37, p. 22815-22 7 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    50. Published

      Structure of the T cell receptor in a Ti alpha V beta 2, alpha V beta 8-positive T cell line

      Hou, X., Dietrich, J., Kuhlmann, J., Wegener, A. M. & Geisler, Carsten, 1994, In: European Journal of Immunology. 24, 5, p. 1228-33 5 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

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