Carsten Geisler

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Primary fields of research

https://sic.ku.dk/research/t-cell-biology-and-skin-inflammation/

Current research

https://sic.ku.dk/research/t-cell-biology-and-skin-inflammation/

Selected publications

1. Published

   Vitamin D controls T cell antigen receptor signaling and activation of human T cells

   von Essen, Marina Rode, Kongsbak-Wismann, Martin, Schjerling, Peter, Ølgaard, Klaus, Ødum, Niels & Geisler, Carsten, 2010, In: Nature Immunology. 11, 4, p. 344-349 5 p.

   Research output: Contribution to journal › Journal article › Research › peer-review

2. Published

   TCR down-regulation controls T cell homeostasis

   Boding, L., Bonefeld, C. M., Nielsen, B. L., Lauritsen, J. P. H., von Essen, Marina Rode, Hansen, A. K., Larsen, J. M., Nielsen, M. M., Ødum, Niels & Geisler, Carsten, 2009, In: Journal of Immunology. 183, 8, p. 4994-5005 11 p.

   Research output: Contribution to journal › Journal article › Research › peer-review

3. Published

   Protein kinase C (PKC) alpha and PKC theta are the major PKC isotypes involved in TCR down-regulation

   von Essen, Marina Rode, Nielsen, M. W., Bonefeld, C. M., Boding, L., Larsen, J. M., Leitges, M., Baier, G., Odum, N. & Geisler, Carsten, 2006, In: Journal of Immunology. 176, 12, p. 7502-10 8 p.

   Research output: Contribution to journal › Journal article › Research › peer-review

4. Published

   Constitutive and ligand-induced TCR degradation

   von Essen, Marina Rode, Bonefeld, C. M., Siersma, Volkert Dirk, Rasmussen, A. B., Lauritsen, J. P. H., Nielsen, B. L. & Geisler, Carsten, 2004, In: Journal of Immunology. 173, 1, p. 384-93 9 p.

   Research output: Contribution to journal › Journal article › Research › peer-review

5. Published

   TCR trafficking in resting and stimulated T cells

   Geisler, Carsten, 2004, In: Critical Reviews in Immunology. 24, 1, p. 67-86 19 p.

   Research output: Contribution to journal › Journal article › Research › peer-review

6. Published

   TCR comodulation of nonengaged TCR takes place by a protein kinase C and CD3 gamma di-leucine-based motif-dependent mechanism

   Bonefeld, C. M., Rasmussen, B. A., Lauritsen, J. P., von Essen, Marina Rode, Ødum, Niels, Andersen, P. S. & Geisler, Carsten, 2003, In: Journal of Immunology. 171, 6, p. 3003-9 6 p.

   Research output: Contribution to journal › Journal article › Research › peer-review

7. Published

   Endo- and exocytic rate constants for spontaneous and protein kinase C-activated T cell receptor cycling

   Menné, C., Møller Sørensen, T., Siersma, Volkert Dirk, von Essen, Marina Rode, Ødum, Niels & Geisler, Carsten, 2002, In: European Journal of Immunology. 32, 3, p. 616-26 10 p.

   Research output: Contribution to journal › Journal article › Research › peer-review

8. Published

   Ligand-induced TCR down-regulation is not dependent on constitutive TCR cycling

   Dietrich, J., Menné, C., Lauritsen, J. P. H., von Essen, Marina Rode, Rasmussen, B. A., Ødum, Niels & Geisler, Carsten, 2002, In: Journal of Immunology. 168, 11, p. 5434-40 6 p.

   Research output: Contribution to journal › Journal article › Research › peer-review

9. Published

   The CD3 gamma leucine-based receptor-sorting motif is required for efficient ligand-mediated TCR down-regulation

   von Essen, Marina Rode, Menné, C., Nielsen, B. L., Lauritsen, J. P. H., Dietrich, J., Andersen, P. S., Karjalainen, K., Ødum, Niels & Geisler, Carsten, 2002, In: Journal of Immunology. 168, 9, p. 4519-23 4 p.

   Research output: Contribution to journal › Journal article › Research › peer-review

10. Published

    Leucine-based receptor sorting motifs are dependent on the spacing relative to the plasma membrane

    Geisler, Carsten, Dietrich, J., Nielsen, B. L., Kastrup, J., Lauritsen, J. P. H., Ødum, Niels & Bartels, Mette Damkjær, 1998, In: Journal of Biological Chemistry. 273, 33, p. 21316-23 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

11. Published

    The phosphorylation state of CD3gamma influences T cell responsiveness and controls T cell receptor cycling

    Dietrich, J., Bäckström, T., Lauritsen, J. P., Kastrup, J., Bartels, Mette Damkjær, von Bülow, F., Palmer, E. & Geisler, Carsten, 1998, In: Journal of Biological Chemistry. 273, 37, p. 24232-8 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

12. Published

    Two distinct pathways exist for down-regulation of the TCR

    Lauritsen, J. P., Bartels, Mette Damkjær, Dietrich, J., Kastrup, J., Odum, N. & Geisler, Carsten, 1998, In: Journal of Immunology. 161, 1, p. 260-7 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

13. Published

    Regulation and function of the CD3¿ DxxxLL motif: a binding site for adaptor protein-1 and adaptor protein-2 in vitro

    Dietrich, J., Kastrup, J., Nielsen, B. L., Odum, N. & Geisler, Carsten, 1997, In: Journal of Cell Biology. 138, 2, p. 271-81 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

14. Published

    Molecular characterization of the di-leucine-based internalization motif of the T cell receptor

    Dietrich, J., Hou, X., Wegener, A. M., Pedersen, L. O., Odum, N. & Geisler, Carsten, 1996, In: Journal of Biological Chemistry. 271, 19, p. 11441-8 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

15. Published

    Role of CD3 gamma in T cell receptor assembly

    Dietrich, J., Neisig, A., Hou, X., Wegener, A. M., Gajhede, Michael & Geisler, Carsten, 1996, In: Journal of Cell Biology. 132, 3, p. 299-310 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

16. Published

    Distinct domains of the CD3-gamma chain are involved in surface expression and function of the T cell antigen receptor

    Wegener, A. M., Hou, X., Dietrich, J. & Geisler, Carsten, 1995, In: Journal of Biological Chemistry. 270, 9, p. 4675-80 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

17. Published

    CD3 gamma contains a phosphoserine-dependent di-leucine motif involved in down-regulation of the T cell receptor

    Dietrich, J., Hou, X., Wegener, A. M. & Geisler, Carsten, 1994, In: EMBO Journal. 13, 9, p. 2156-66 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

18. Published

    Failure to synthesize the CD3-gamma chain. Consequences for T cell antigen receptor assembly, processing, and expression

    Geisler, Carsten, 1992, In: Journal of Immunology. 148, 8, p. 2437-45 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review