Carsten Geisler

Carsten Geisler

Professor

Member of:

    ORCID: 0000-0002-8472-0771

    Publication year:
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    51 - 100 out of 219Page size: 50
    1. 1998
    2. Published

      TCR alpha beta chains associate with the plasma membrane independently of CD3 and TCR zeta chains in murine primary T cells

      Zhang, J., Salojin, K., Gao, J. X., Cameron, M., Geisler, Carsten & Delovitch, T. L., 1998, In: Journal of Immunology. 161, 6, p. 2930-7 7 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    3. Published

      The phosphorylation state of CD3gamma influences T cell responsiveness and controls T cell receptor cycling

      Dietrich, J., Bäckström, T., Lauritsen, J. P., Kastrup, J., Bartels, Mette Damkjær, von Bülow, F., Palmer, E. & Geisler, Carsten, 1998, In: Journal of Biological Chemistry. 273, 37, p. 24232-8 6 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    4. Published

      The role of caspase 3 and BclxL in the action of interleukin 7 (IL-7): a survival factor in activated human T cells

      Amos, C. L., Woetmann, Anders , Nielsen, M., Geisler, Carsten, Odum, N., Brown, B. L. & Dobson, P. R., 1998, In: Cytokine. 10, 9, p. 662-8 6 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    5. Published

      Two distinct pathways exist for down-regulation of the TCR

      Lauritsen, J. P., Bartels, Mette Damkjær, Dietrich, J., Kastrup, J., Odum, N. & Geisler, Carsten, 1998, In: Journal of Immunology. 161, 1, p. 260-7 7 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    6. 1999
    7. Published

      Cutting edge: TCR stimulation by antibody and bacterial superantigen induces Stat3 activation in human T cells

      Gerwien, J., Nielsen, M., Labuda, T., Nissen, M. H., Svejgaard, A., Geisler, Carsten, Röpke, C. & Odum, N., 1999, In: Journal of Immunology. 163, 4, p. 1742-5 3 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    8. Published

      Inhibition of constitutively activated Stat3 correlates with altered Bcl-2/Bax expression and induction of apoptosis in mycosis fungoides tumor cells

      Nielsen, M., Kaestel, C. G., Eriksen, K. W., Woetmann, Anders , Stokkedal, T., Kaltoft, K., Geisler, Carsten, Röpke, C. & Odum, N., 1999, In: Leukemia. 13, 5, p. 735-8 3 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    9. Published

      Inhibition of protein phosphatase 2A induces serine/threonine phosphorylation, subcellular redistribution, and functional inhibition of STAT3

      Woetmann, Anders , Nielsen, M., Christensen, S. T., Brockdorff, J., Kaltoft, K., Engel, A. M., Skov, S., Brender, C., Geisler, Carsten, Svejgaard, A., Rygaard, J., Leick, V. & Odum, N., 1999, In: Proceedings of the National Academy of Science of the United States of America. 96, 19, p. 10620-5 5 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    10. Published

      TCR¿ is transported to and retained in the Golgi apparatus independently of other TCR chains: implications for TCR assembly

      Dietrich, J., Kastrup, J., Lauritsen, J. P. H., Bonefeld, Charlotte Menne, von Bülow, F. & Geisler, Carsten, 1999, In: European Journal of Immunology. 29, 5, p. 1719-28 9 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    11. 2000
    12. Published

      Amino acid substitutions in the melanoma antigen recognized by T cell 1 peptide modulate cytokine responses in melanoma-specific T cells

      Nielsen, M. B., Kirkin, A. F., Loftus, D., Nissen, Mogens Holst, Rivoltini, L., Zeuthen, J., Geisler, Carsten & Odum, N., 2000, In: Journal of Immunotherapy. 23, 4, p. 405-11 6 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    13. Published

      Ceramide-induced TCR up-regulation

      Bonefeld, Charlotte Menne, Lauritsen, J. P. H., Dietrich, J., Kastrup, J., Wegener, A. M., Ødum, Niels & Geisler, Carsten, 2000, In: Journal of Immunology. 165, 6, p. 3065-72 7 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    14. Published

      Lck is involved in interleukin-2 induced proliferation but not cell survival in human T cells through a MAP kinase-independent pathway

      Brockdorff, J., Nielsen, M., Kaltoft, K., Mustelin, T., Röpke, C., Svejaard, A., Geisler, Carsten & Odum, N., 2000, In: European Cytokine Network. 11, 2, p. 225-31 6 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    15. Published

      Recruitment of SHP-1 protein tyrosine phosphatase and signalling by a chimeric T-cell receptor-killer inhibitory receptor

      Bartels, Mette Damkjær & Geisler, Carsten, 2000, In: Scandinavian Journal of Immunology. 51, 6, p. 557-64 7 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    16. Published

      The phosphatase domains of CD45 are required for ligand induced T-cell receptor downregulation

      Kastrup, J., Lauritsen, J. P. H., Bonefeld, Charlotte Menne, Dietrich, J. & Geisler, Carsten, 2000, In: Scandinavian Journal of Immunology. 51, 5, p. 491-6 5 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    17. Published

      beta2-adaptin is constitutively de-phosphorylated by serine/threonine protein phosphatase PP2A and phosphorylated by a staurosporine-sensitive kinase

      Lauritsen, J. P. H., Bonefeld, Charlotte Menne, Kastrup, J., Dietrich, J., Ødum, Niels & Geisler, Carsten, 2000, In: BBA General Subjects. 1497, 3, p. 297-307 10 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    18. 2001
    19. Published

      A response calculus for immobilized T cell receptor ligands

      Andersen, P. S., Bonefeld, Charlotte Menne, Mariuzza, R. A., Geisler, Carsten & Karjalainen, K., 2001, In: Journal of Biological Chemistry. 276, 52, p. 49125-32 7 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    20. Published

      Constitutive STAT3-activation in Sezary syndrome: tyrphostin AG490 inhibits STAT3-activation, interleukin-2 receptor expression and growth of leukemic Sezary cells

      Eriksen, K. W., Kaltoft, K., Mikkelsen, G., Nielsen, M., Zhang, Q., Geisler, Carsten, Nissen, M. H., Röpke, C., Wasik, M. A. & Odum, N., 2001, In: Leukemia. 15, 5, p. 787-93 6 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    21. Published

      Gab2 is phosphorylated on tyrosine upon interleukin-2/interleukin-15 stimulation in mycosis-fungoides-derived tumor T cells and associates inducibly with SHP-2 and Stat5a

      Brockdorff, J. L., Gu, H., Mustelin, T., Kaltoft, K., Geisler, Carsten, Röpke, C. & Ødum, Niels, 2001, In: Experimental and Clinical Immunogenetics. 18, 2, p. 86-95 9 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    22. Published

      Interferon-alpha induces transient suppressors of cytokine signalling expression in human T cells

      Brender, C., Nielsen, M., Röpke, C., Nissen, M. H., Svejgaard, A., Billestrup, N., Geisler, Carsten & Ødum, Niels, 2001, In: Experimental and Clinical Immunogenetics. 18, 2, p. 80-5 5 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    23. Published

      Protein phosphatase 2A isotypes regulate cell surface expression of the T cell receptor

      Lauritsen, J. P. H., Bonefeld, Charlotte Menne, Kastrup, J., Dietrich, J. & Geisler, Carsten, 2001, In: Experimental and Clinical Immunogenetics. 18, 1, p. 24-33 9 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    24. Published

      Role of the T cell receptor ligand affinity in T cell activation by bacterial superantigens

      Andersen, P. S., Geisler, Carsten, Buus, Søren, Mariuzza, R. A. & Karjalainen, K., 2001, In: Journal of Biological Chemistry. 276, 36, p. 33452-7 5 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    25. Published

      T-cell receptor downregulation by ceramide-induced caspase activation and cleavage of the zeta chain

      Bonefeld, Charlotte Menne, Lauritsen, J. P. H., Dietrich, J., Kastrup, J., Wegener, A. K., Andersen, P. S., Odum, N. & Geisler, Carsten, 2001, In: Scandinavian Journal of Immunology. 53, 2, p. 176-83 7 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    26. 2002
    27. Published

      Endo- and exocytic rate constants for spontaneous and protein kinase C-activated T cell receptor cycling

      Bonefeld, Charlotte Menne, Møller Sørensen, T., Siersma, Volkert Dirk, von Essen, Marina Rode, Ødum, Niels & Geisler, Carsten, 2002, In: European Journal of Immunology. 32, 3, p. 616-26 10 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    28. Published

      In vitro production and characterization of partly assembled human CD3 complexes

      Kastrup, J., Pedersen, L. Ø., Dietrich, J., Lauritsen, J. P. H., Bonefeld, Charlotte Menne & Geisler, Carsten, 2002, In: Scandinavian Journal of Immunology. 56, 5, p. 436-42 6 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    29. Published

      Ligand-induced TCR down-regulation is not dependent on constitutive TCR cycling

      Dietrich, J., Bonefeld, Charlotte Menne, Lauritsen, J. P. H., von Essen, Marina Rode, Rasmussen, B. A., Ødum, Niels & Geisler, Carsten, 2002, In: Journal of Immunology. 168, 11, p. 5434-40 6 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    30. Published

      Protein phosphatase 2A (PP2A) regulates interleukin-4-mediated STAT6 signaling

      Woetmann, Anders , Brockdorff, J., Lovato, P., Nielsen, M., Leick, V., Rieneck, K., Svejgaard, A., Geisler, Carsten & Ødum, Niels, 2002, In: Journal of Biological Chemistry. 278, 5, p. 2787-91 4 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    31. Published

      Quantifying the energetics of cooperativity in a ternary protein complex

      Andersen, P. S., Schuck, P., Sundberg, E. J., Geisler, Carsten, Karjalainen, K. & Mariuzza, R. A., 2002, In: Biochemistry. 41, 16, p. 5177-84 7 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    32. Published

      Spontaneous interleukin-5 production in cutaneous T-cell lymphoma lines is mediated by constitutively activated Stat3

      Nielsen, M., Nissen, Mogens Holst, Gerwien, J., Zocca, M., Rasmussen, H. M., Nakajima, K., Röpke, C., Geisler, Carsten, Kaltoft, K. & Ødum, Niels, 2002, In: Blood. 99, 3, p. 973-7 4 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    33. Published

      The CD3 gamma leucine-based receptor-sorting motif is required for efficient ligand-mediated TCR down-regulation

      von Essen, Marina Rode, Bonefeld, Charlotte Menne, Nielsen, B. L., Lauritsen, J. P. H., Dietrich, J., Andersen, P. S., Karjalainen, K., Ødum, Niels & Geisler, Carsten, 2002, In: Journal of Immunology. 168, 9, p. 4519-23 4 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    34. 2003
    35. Published

      Bi-phasic effect of interferon (IFN)-alpha: IFN-alpha up- and down-regulates interleukin-4 signaling in human T cells

      Eriksen, K. W., Sommer, V. H., Woetmann, Anders , Rasmussen, A. B., Brender, C., Svejgaard, A., Skov, Søren, Geisler, Carsten & Ødum, Niels, 2003, In: Journal of Biological Chemistry. 279, 1, p. 169-76 7 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    36. Published

      TCR comodulation of nonengaged TCR takes place by a protein kinase C and CD3 gamma di-leucine-based motif-dependent mechanism

      Bonefeld, Charlotte Menne, Rasmussen, B. A., Lauritsen, J. P., von Essen, Marina Rode, Ødum, Niels, Andersen, P. S. & Geisler, Carsten, 2003, In: Journal of Immunology. 171, 6, p. 3003-9 6 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    37. Published

      The immunological synapse

      Klemmensen, T., Pedersen, L. O. & Geisler, Carsten, 2003, In: Archivum Immunologiae et Therapiae Experimentalis. 51, 6, p. 377-88 11 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    38. 2004
    39. Published

      Constitutive and ligand-induced TCR degradation

      von Essen, Marina Rode, Bonefeld, Charlotte Menne, Siersma, Volkert Dirk, Rasmussen, A. B., Lauritsen, J. P. H., Nielsen, B. L. & Geisler, Carsten, 2004, In: Journal of Immunology. 173, 1, p. 384-93 9 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    40. Published

      Masking of the CD3 gamma di-leucine-based motif by zeta is required for efficient T-cell receptor expression

      Lauritsen, J. P. H., Bonefeld, Charlotte Menne, von Essen, Marina Rode, Nielsen, M. W., Rasmussen, A. B., Ødum, Niels, Dietrich, J. & Geisler, Carsten, 2004, In: Traffic - International Journal of Intracellular Transport. 5, 9, p. 672-84 12 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    41. Published

      Proteasomal targeting and minigene repetition improve cell-surface presentation of a transfected, modified melanoma tumour antigen

      Rasmussen, A. B., Zocca, M., Bonefeld, Charlotte Menne, von Essen, Marina Rode, Lauritsen, J. P., Tomra, S., Ødum, Niels & Geisler, Carsten, 2004, In: Scandinavian Journal of Immunology. 59, 2, p. 220-7 7 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    42. Published

      TCR trafficking in resting and stimulated T cells

      Geisler, Carsten, 2004, In: Critical Reviews in Immunology. 24, 1, p. 67-86 19 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    43. 2005
    44. Published

      Constitutive SOCS-3 expression protects T-cell lymphoma against growth inhibition by IFNalpha

      Brender, C., Lovato, P., Sommer, V. H., Woetmann, Anders , Mathiesen, A., Geisler, Carsten, Wasik, M. & Ødum, Niels, 2005, In: Leukemia. 19, 2, p. 209-13 4 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    45. Published

      Increased sensitivity to interferon-alpha in psoriatic T cells

      Eriksen, K. W., Lovato, P., Skov, Lone, Krejsgaard, T., Kaltoft, K., Geisler, Carsten & Ødum, Niels, 2005, In: Journal of Investigative Dermatology. 125, 5, p. 936-44 8 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    46. 2006
    47. Published

      Protein kinase C (PKC) alpha and PKC theta are the major PKC isotypes involved in TCR down-regulation

      von Essen, Marina Rode, Nielsen, M. W., Bonefeld, Charlotte Menne, Boding, L., Larsen, J. M., Leitges, M., Baier, G., Odum, N. & Geisler, Carsten, 2006, In: Journal of Immunology. 176, 12, p. 7502-10 8 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    48. 2007
    49. Published

      Cellular dynamics in the draining lymph nodes during sensitization and elicitation phases of contact hypersensitivity

      Larsen, J. M., Geisler, Carsten, Nielsen, M. W., Boding, L., von Essen, Marina Rode, Hansen, A. K., Skov, Lone & Bonefeld, Charlotte Menne, 2007, In: Contact Dermatitis. 57, 5, p. 300-8 8 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    50. Published

      Nonmalignant T cells stimulate growth of T-cell lymphoma cells in the presence of bacterial toxins

      Woetmann, Anders , Lovato, P., Eriksen, K. W., Krejsgaard, T., Labuda, T., Zhang, Q., Mathiesen, A., Geisler, Carsten, Svejgaard, A., Wasik, M. A. & Ødum, Niels, 2007, In: Blood. 109, 8, p. 3325-32 7 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    51. Published

      The adjuvant mechanism of cationic dimethyldioctadecylammonium liposomes

      Korsholm, K. S., Agger, E. M., Foged, Camilla, Christensen, D., Dietrich, J., Andersen, C. S., Geisler, Carsten & Andersen, P., 2007, In: Immunology. 121, 2, p. 216-26 10 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    52. 2008
    53. Published

      Age-dependent decrease of allergic contact dermatitis correlates to diminished allergen-specific Th17 and Th1 responses, and enhanced immune regulation in ageing mice

      Nielsen, M. K. W., Larsen, J. M., Hansen, A., Boding, L., von Essen, Marina Rode, Geisler, Carsten, Skov, L. & Bonefeld, Charlotte Menne, 2008, In: Journal of Investigative Dermatology. 128, Suppl. 1, p. S180-S180

      Research output: Contribution to journal › Journal article › Research › peer-review

    54. Published

      Malignant Tregs express low molecular splice forms of FOXP3 in Sézary syndrome

      Krejsgaard, T., Gjerdrum, L. M., Ralfkiaer, E., Lauenborg, B., Eriksen, K. W., Mathiesen, A., Bovin, L. F., Gniadecki, R., Geisler, Carsten, Ryder, L. P., Zhang, Q., Wasik, M. A., Ødum, Niels & Woetmann, Anders , 2008, In: Leukemia. p. 2230-2239 9 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    55. Published

      The combination of IL-21 and IFN-alpha boosts STAT3 activation, cytotoxicity and experimental tumor therapy

      Eriksen, K. W., Søndergaard, H., Woetmann, Anders , Krejsgaard, T., Skak, K., Geisler, Carsten, Wasik, M. A. & Odum, N., 2008, In: Molecular Immunology. 46, 5, p. 812-20 8 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    56. 2009
    57. Published

      Ectopic expression of B-lymphoid kinase in cutaneous T-cell lymphoma

      Krejsgaard, T., Vetter-Kauczok, C. S., Woetmann, Anders , Kneitz, H., Eriksen, K. W., Lovato, P., Zhang, Q., Wasik, M. A., Geisler, Carsten, Ralfkiaer, E., Becker, J. C. & Ødum, Niels, 2009, In: Blood. 113, 23, p. 5896-904 8 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    58. Published

      IL-23 and T(H)17-mediated inflammation in human allergic contact dermatitis

      Larsen, J. M., Bonefeld, Charlotte Menne, Poulsen, Steen Seier, Geisler, Carsten & Skov, Lone, 2009, In: Journal of Allergy and Clinical Immunology. 123, 2, p. 486-92 6 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    59. Published

      TCR down-regulation controls T cell homeostasis

      Boding, L., Bonefeld, Charlotte Menne, Nielsen, B. L., Lauritsen, J. P. H., von Essen, Marina Rode, Hansen, A. K., Larsen, J. M., Nielsen, M. M., Ødum, Niels & Geisler, Carsten, 2009, In: Journal of Immunology. 183, 8, p. 4994-5005 11 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    60. Published

      TCR down-regulation controls virus-specific CD8+ T cell responses

      Bonefeld, Charlotte Menne, Haks, M., Nielsen, B., von Essen, Marina Rode, Boding, L., Hansen, A. K., Larsen, J. M., Ødum, Niels, Krimpenfort, P., Kruisbeek, A., Christensen, Jan Pravsgaard, Thomsen, Allan Randrup & Geisler, Carsten, 1 Dec 2009, In: Journal of Immunology. 181, 11, p. 7786-7799 14 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    61. 2010
    62. Published

      A novel xenograft model of cutaneous T-cell lymphoma

      Krejsgaard, T., Kopp, K., Ralfkiaer, E., Willumsgaard, A. E., Eriksen, K. W., Labuda, T., Rasmussen, S., Mathiesen, A., Geisler, Carsten, Lauenborg, B., Becker, J. C., Zhang, Q., Wasik, M. A., Ødum, Niels & Woetmann, Anders , 2010, In: Experimental Dermatology. 19, 12, p. 1096-102 7 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    63. Published

      COX-2-dependent PGE2 acts as a growth factor in mycosis fungoides (MF)

      Kopp, K. L. M., Kauczok, C. S., Lauenborg, B. T., Krejsgaard, T. F., Eriksen, K. W. K., Zhang, Q., Wasik, M. A., Geisler, Carsten, Ralfkiaer, E. M., Becker, J. C., Ødum, Niels & Woetmann, Anders , 2010, In: Leukemia. 24, 6, p. 1179-1185 7 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

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    ID: 10043