Niels Ødum
Professor
Skin Immunology Research Center
Blegdamsvej 3B, 2200 København N, 07 Bygning 7, Building: 07-12-86
Member of:
- Published
Staphylococcal enterotoxins modulate interleukin 2 receptor expression and ligand-induced tyrosine phosphorylation of the Janus protein-tyrosine kinase 3 (Jak3) and signal transducers and activators of transcription (Stat proteins)
Nielsen, M., Svejgaard, A., Röpke, C., Nordahl, M. & Ødum, Niels, 1995, In: Proceedings of the National Academy of Science of the United States of America. 92, 24, p. 10995-9 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Interleukin-2 and -15 activate Stat 3a in human T lymphocytes
Nielsen, M., Pedersen, M. N., Svejgaard, A. & Ødum, Niels, 1998, In: Cytokine. 10, p. 735-738Research output: Contribution to journal › Journal article › Research
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Spontaneous interleukin-5 production in cutaneous T-cell lymphoma lines is mediated by constitutively activated Stat3
Nielsen, M., Nissen, Mogens Holst, Gerwien, J., Zocca, M., Rasmussen, H. M., Nakajima, K., Röpke, C., Geisler, Carsten, Kaltoft, K. & Ødum, Niels, 2002, In: Blood. 99, 3, p. 973-7 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Interleukine-2 induces tyrosine phosphorylation and nuclear translocation of stat3 in human T lymphocytes
Nielsen, M., Svejgaard, A., Skov, S. & Ødum, Niels, 1994, In: European Journal of Immunology. 12, p. 3082Research output: Contribution to journal › Journal article › Research
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IL-1β-Dependent Activation of Dendritic Epidermal T Cells in Contact Hypersensitivity
Nielsen, M. M., Lovato, P., Macleod, A. S., Witherden, D. A., Skov, Lone, Dyring-Andersen, Beatrice, Dabelsteen, Sally, Woetmann, Anders , Ødum, Niels, Havran, W. L., Geisler, Carsten & Bonefeld, Charlotte Menne, 1 Apr 2014, In: Journal of immunology (Baltimore, Md. : 1950). 192, 7, p. 2975-83 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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NKG2D-Dependent Activation of Dendritic Epidermal T cells in Contact Hypersensitivity
Nielsen, M. M., Dyring-Andersen, Beatrice, Schmidt, J. D., Witherden, D., Lovato, P., Woetmann, Anders , Ødum, Niels, Poulsen, Steen Seier, Havran, W. L., Geisler, Carsten & Bonefeld, Charlotte Menne, May 2015, In: Journal of Investigative Dermatology. 135, 5, p. 1311-19 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Cytotoxicity of CD56bright NK cells towards autologous activated CD4+ T cells is mediated through NKG2D, LFA-1 and TRAIL and dampened via CD94/NKG2A
Nielsen, N., Ødum, Niels, Ursø, B., Lanier, L. L. & Spee, P., 2012, In: PLoS ONE. 7, 2, 10 p., e31959.Research output: Contribution to journal › Journal article › Research › peer-review
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Clinical and histological characteristics of mycosis fungoides and sézary syndrome: A retrospective, single-centre study of 43 patients from eastern Denmark
Nielsen, P. R., Eriksen, J. O., Wehkamp, U., Lindahl, L. M., Gniadecki, R., Fogh, H., Fabricius, S., Bzorek, M., Ødum, Niels & Gjerdrum, Lise Mette Rahbek, 2019, In: Acta Dermato-Venereologica. 99, 13, p. 1231-1236 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Role of B-cells in mycosis fungoides
Nielsen, Pia Rude, Eriksen, J. O., Sørensen, M. D., Wehkamp, U., Lindahl, L. M., Bzorek, M., Iversen, L., Woetmann, Anders , Ødum, Niels, Litman, Thomas & Gjerdrum, Lise Mette Rahbek, 2021, In: Acta Dermato-Venereologica. 101, 3, adv00413.Research output: Contribution to journal › Journal article › Research › peer-review
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Diagnostic Two-Gene Classifier in Early-Stage Mycosis Fungoides: A Retrospective Multicenter Study
Nielsen, Pia Rude, Eriksen, J. O., Lindahl, L. M., Wehkamp, U., Bzorek, M., Andersen, G., Woetmann, Anders , Iversen, L., Ødum, Niels, Litman, Thomas & Gjerdrum, Lise Mette Rahbek, 2021, In: Journal of Investigative Dermatology. 141, 1, p. 213-217.e5Research output: Contribution to journal › Letter › Research › peer-review
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MiR137 is an androgen regulated repressor of an extended network of transcriptional coregulators
Nilsson, E. M., Laursen, K. B., Whitchurch, J., McWilliam, A., Ødum, Niels, Persson, J. L., Heery, D. M., Gudas, L. J. & Mongan, N. P., 2015, In: OncoTarget. 6, 34, p. 35710-35725 16 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Omalizumab serum levels predict treatment outcomes in patients with chronic spontaneous urticaria: A three months prospective study
Noshela Ghazanfar, M., Bartko, E. A., Arildsen, Nicolai Skovbjerg, Poulsen, Lars K., Jensen, B. M., Enevold, C., Holm, J. G., Woetmann, Anders , Ødum, Niels & Thomsen, Simon Francis, 2022, In: Clinical and Experimental Allergy. 52, 4 p.Research output: Contribution to journal › Comment/debate › Research
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Signal transduction by HLA-DR is mediated by tyrosine kinase(s) and regulated by CD45 in activated T cells
Ødum, Niels, Martin, P. J., Schieven, G. L., Norris, N. A., Grosmaire, L. S., Hansen, J. A. & Ledbetter, J. A., 1991, In: Human Immunology. 32, 2, p. 85-94 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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MHC class II molecules deliver costimulatory signals in human T cells through a functional linkage with IL-2-receptors
Ødum, Niels, Kanner, S. B., Ledbetter, J. A. & Svejgaard, A., 1993, In: Journal of Immunology. 150, 12, p. 5289-98 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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HLA-DR molecules enhance signal transduction through the CD3/Ti complex in activated T cells
Ødum, Niels, Martin, P. J., Schieven, G. L., Masewicz, S., Hansen, J. A. & Ledbetter, J. A., 1991, In: HLA. 38, 2, p. 72-7 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Homotypic aggregation of human cell lines by HLA class II-, class Ia- and HLA-G-specific monoclonal antibodies
Ødum, Niels, Ledbetter, J. A., Martin, P., Geraghty, D., Tsu, T., Hansen, J. A. & Gladstone, P., 1991, In: European Journal of Immunology. 21, 9, p. 2121-31 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Signal transduction by HLA class II molecules in human T cells: induction of LFA-1-dependent and independent adhesion
Ødum, Niels, Yoshizumi, H., Okamoto, Y., Kamikawaji, N., Kimura, A., Nishimura, Y. & Sasazuki, T., 1992, In: Human Immunology. 35, 2, p. 71-84 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Haematopoietic stem cells and their niches: Comment on: Miftakhova R, et al. Cyclin A1 regulates the interactions betweenmouse haematopoietic stem and progenitor cells and their niches. Cell Cycle2015; 14(12):1948-60; PMID:25785996;http://doi.dx.org/10.1080/15384101.2015.1026513
Ødum, Niels, 2015, In: Cell Cycle. 14, 22, p. 3524-3525 2 p.Research output: Contribution to journal › Comment/debate › Research › peer-review
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Arne Svejgaard and immunogenetics in Denmark
Ødum, Niels, Fugger, L. & Dickmeiss, E., 1997, In: HLA. 49, 3, p. 291-2 1 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Effect of praziquantel on human lymphocyte proliferation in vitro
Ødum, Niels, Theander, Thor Grundtvig & Bygbjerg, Ib Christian, 1984, In: European Journal of Clinical Pharmacology. 27, 3, p. 311-3 2 p.Research output: Contribution to journal › Journal article › Research › peer-review
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The CC-chemokine receptor 5 (CCR5) is a marker of, but not essential for the development of human Th1 cells
Ødum, Niels, Bregenholt, S., Eriksen, K. W., Skov, S., Ryder, L. P., Bendtzen, K., Van Neerven, R. J., Svejgaard, A. & Garred, Peter, 1999, In: HLA. 54, 6, p. 572-7 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
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IKca Channel Blocking compounds/immunosuppressiva
Olesen, S., Jensen, B. S., Jørgensen, T. H., Strøbæk, D., Christoffersen, P. & Ødum, Niels, 1999, PCT.Research output: Book/Report › Book › Research
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Increased frequency of HLA-DR2 in patients with Darier's disease
Oxholm, A., Oxholm, P., da Cunha Bang, F., Prause, J. U., Odum, N., Jakobsen, B. K., Svejgaard, A. & Ødum, Niels, 1990, In: British Journal of Dermatology. 123, 6, p. 845Research output: Contribution to journal › Journal article › Research › peer-review
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Endolysin Inhibits Skin Colonization by Patient-Derived Staphylococcus Aureus and Malignant T-Cell Activation in Cutaneous T-Cell Lymphoma
Pallesen, E. M. H., Gluud, M., Vadivel, C. K., Buus, T. B., de Rooij, B., Zeng, Z., Ahmad, S., Willerslev-Olsen, A., Röhrig, C., Kamstrup, M. R., Bay, L., Lindahl, L., Krejsgaard, T., Geisler, C., Bonefeld, C. M., Iversen, L., Woetmann, A., Koralov, S. B., Bjarnsholt, T., Frieling, J. & 2 others, , 2023, In: Journal of Investigative Dermatology. 143, 9, p. 1757-1769 15 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Selective modulation of the CD4 molecular complex by Pseudomonas aeruginosa alkaline protease and elastase
Pedersen, Bente Klarlund, Kharazmi, A., Theander, Thor Grundtvig, Ødum, Niels, Andersen, V. & Bendtzen, K., 1987, In: Scandinavian Journal of Immunology. 26, 1, p. 91-4 3 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Vascular endothelial growth factor receptor-3 expression in mycosis fungoides
Pedersen, I. H., Willerslev-Olsen, A., Vetter-Kauczok, C., Krejsgaard, T., Lauenborg, B., Kopp, K. L., Geisler, Carsten, Bonefeld, Charlotte Menne, Zhang, Q., Wasik, M. A., Dabelsteen, Sally, Woetmann, Anders , Becker, J. C. & Ødum, Niels, 2012, In: Leukemia and Lymphoma.Research output: Contribution to journal › Journal article › Research › peer-review
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Phenotypic plasticity of malignant T cells in blood and skin of a Sézary syndrome patient revealed by single cell transcriptomics
Peiffer, L., Gambichler, T., Buus, Terkild Brink, Horny, K., Gravemeyer, J., Furtmann, F., Spassova, I., Kubat, L., Susok, L., Stranzenbach, R., Srinivas, N., Ødum, Niels & Becker, J. C., 2023, In: Frontiers in Oncology. 13, 1090592.Research output: Contribution to journal › Journal article › Research › peer-review
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TGFβ-derived immune modulatory vaccine: targeting the immunosuppressive and fibrotic tumor microenvironment in a murine model of pancreatic cancer
Perez Penco, Maria, Weis-Banke, S. E., Schina, A., Siersbæk, M., Hübbe, M. L., Jørgensen, M. A., Lecoq, I., Lara De La Torre, L., Bendtsen, S. K., Martinenaite, E., Holmström, M. O., Madsen, Daniel Hargbøl, dqp123, dqp123, Ødum, Niels, Grøntved, L. & Andersen, Mads Hald, 2022, In: Journal for ImmunoTherapy of Cancer. 10, 12, 15 p., e005491.Research output: Contribution to journal › Journal article › Research › peer-review
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B-lymphoid tyrosine kinase (Blk) is an oncogene and a potential target for therapy with Dasatinib in cutaneous T-cell lymphoma (CTCL)
Petersen, D. L., Krejsgaard, T., Berthelsen, J., Fredholm, S., Willerslev-Olsen, A., Sibbesen, N. A., Bonefeld, Charlotte Menne, Andersen, M. H., Francavilla, C., Olsen, Jesper Velgaard, Hu, T., Zhang, M., Wasik, M. A., Geisler, Carsten, Woetmann, Anders & Ødum, Niels, 12 Jun 2014, In: Leukemia. 28, p. 2109-12 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
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MICRORNA 203 CONTROLS T-CELL LYMPHOMAGENESIS BY TARGETING IL-2 RECEPTOR SIGNALING
Ralfkiaer, U., Jansson, Martin David, Kopp, K., Willerslev-Olsen, A., Asmar, F., Krejsgaard, T., Brown, P., Gniadecki, R., Woetmann, Anders , Lund, Anders H., Ødum, Niels & Grønbæk, Kirsten, 22 Jun 2015, In: Haematologica. 100, supplement 1, p. 104-105 2 p., P317.Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
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Diagnostic microRNA profiling in cutaneous T-cell lymphoma (CTCL)
Ralfkiaer, U., Hagedorn, P., Bangsgaard, N., Løvendorf, M. B., Ahler, C. B., Svensson, L., Kopp, K. L., Vennegaard, M. T., Lauenborg, B., Zibert, J. R., Krejsgaard, T., Bonefeld, C. M., Søkilde, R., Gjerdrum, L. M., Labuda, T., Mathiesen, A-M., Grønbaek, K., Wasik, M. A., Sokolowska-Wojdylo, M., Queille-Roussel, C. & 9 others, , 2011, In: Blood. 118, 22, p. 5891-5900 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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MicroRNA expression in early mycosis fungoides is distinctly different from atopic dermatitis and advanced cutaneous T-cell lymphoma
Ralfkiaer, U., Lindahl, L. M., Litman, Thomas, Gjerdrum, Lise Mette Rahbek, Ahler, C. B., Gniadecki, R., Marstrand, T., Fredholm, S., Iversen, L., Wasik, M. A., Bonefeld, Charlotte Menne, Geisler, Carsten, Krejsgaard, T., Glue, C., Røpke, M. A., Woetmann, A., Skov, Lone, Grønbæk, Kirsten & Ødum, Niels, Dec 2014, In: Anticancer Research. 34, 12, p. 7207-17 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Proteasomal targeting and minigene repetition improve cell-surface presentation of a transfected, modified melanoma tumour antigen
Rasmussen, A. B., Zocca, M., Bonefeld, Charlotte Menne, von Essen, Marina Rode, Lauritsen, J. P., Tomra, S., Ødum, Niels & Geisler, Carsten, 2004, In: Scandinavian Journal of Immunology. 59, 2, p. 220-7 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Suppressed microRNA-195-5p expression in mycosis fungoides promotes tumor cell proliferation
Rittig, A. H., Johansen, C., Celis, P., Ødum, Niels, Litman, Thomas, Woetmann, Anders , Lindahl, L. M. & Iversen, L., 2021, In: Experimental Dermatology. 30, 8, p. 1141-1149Research output: Contribution to journal › Journal article › Research › peer-review
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The microRNA expression profile differs between erythrodermic mycosis fungoides and Sézary syndrome
Rittig, A. H., Lindahl, L. M., Johansen, C., Celis, P., Ødum, Niels, Iversen, L. & Litman, Thomas, 2019, In: Acta Dermato-Venereologica. 99, 12, p. 1148-1153 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Vitamin D counteracts Mycobacterium tuberculosis-induced cathelicidin downregulation in dendritic cells and allows Th1 differentiation and IFNγ secretion
Rode, A. K. O., Kongsbak-Wismann, Martin, Hansen, M. M., Lopez, D. V., Levring, T. B., Woetmann, Anders , Ødum, Niels, Bonefeld, Charlotte Menne & Geisler, Carsten, May 2017, In: Frontiers in Immunology. 8, 12 p., 656.Research output: Contribution to journal › Journal article › Research › peer-review
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Induced Human Regulatory T Cells Express the Glucagon-like Peptide-1 Receptor
Rode, A. K. O., Buus, Terkild Brink, Mraz, Veronika, Al-Jaberi, F. A. H., Lopez, D. V., Ford, Shayne Lavondua, Hennen, S., Eliasen, I. P., Klewe, I. V., Gharehdaghi, L., Dragan, A., Rosenkilde, Mette, Woetmann, Anders , Skov, Lone, Ødum, Niels, Bonefeld, Charlotte Menne, Kongsbak-Wismann, Martin & Geisler, Carsten, 2022, In: Cells. 11, 16, 2587.Research output: Contribution to journal › Journal article › Research › peer-review
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Expression of full-length and splice forms of FoxP3 in rheumatoid arthritis
Ryder, L. R., Woetmann, Anders , Madsen, H. O., Ødum, Niels, Ryder, L. P., Bliddal, H., Danneskiold-Samsøe, B., Ribel-Madsen, S., Bartels, E. M., Ryder, L. R., Danielsen, A. L. W., Madsen, H. O., Ødum, N., Ryder, L. P., Bliddal, Henning, Danneskiold-Samsøe, B., Ribel-Madsen, S. & Bartels, E. M., 1 Aug 2010, In: Scandinavian Journal of Rheumatology. 39, 4, p. 279-86 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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FoxP3 mRNA splice forms in synovial CD4+ T cells in rheumatoid arthritis and psoriatic arthritis
Ryder, L. R., Bartels, E. M., Woetmann, Anders , Madsen, H. O., Ødum, Niels, Bliddal, H., Danneskiold-Samsøe, B., Ribel-Madsen, S. & Ryder, L. P., May 2012, In: APMIS : acta pathologica, microbiologica, et immunologica Scandinavica. 120, 5, p. 387-396 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Differential effects of decoy receptor- and antibody-mediated tumour necrosis factor blockage on FoxP3 expression in responsive arthritis patients
Ryder, L. R., Ryder, L. P., Bartels, E. M., Woetmann, Anders , Madsen, H. O., Ødum, Niels, Danneskiold-Samsøe, B., Ribel-Madsen, S. & Bliddal, Henning, Apr 2013, In: APMIS : acta pathologica, microbiologica, et immunologica Scandinavica. 121, 4, p. 337-47 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Differential effects of decoy receptor- and antibody-mediated tumour necrosis factor blockage on FoxP3 expression in responsive arthritis patients
Ryder, L. R., Ryder, L. P., Bartels, E. M., Woetmann, Anders , Madsen, H. O., Ødum, Niels, Danneskiold-Samsøe, B., Ribel-Madsen, S. & Bliddal, Henning, 2013, In: A P M I S. Acta Pathologica, Microbiologica et Immunologica Scandinavica. 121, 4, p. 337-347 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Apoptosis following interleukin-2 withdrawal from T cells: evidence for a regulatory role of CD18 (beta 2-integrin) molecules
Röpke, C., Gladstone, P., Nielsen, M., Borregaard, N., Ledbetter, J. A., Svejgaard, A. & Ødum, Niels, 1996, In: HLA. 48, 2, p. 127-35 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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The role of PIP5K1α/pAKT and targeted inhibition of growth of subtypes of breast cancer using PIP5K1α inhibitor
Sarwar, M., Syed Khaja, A. S., Aleskandarany, M., Karlsson, R., Althobiti, M., Ødum, Niels, Mongan, N. P., Dizeyi, N., Johnson, H., Green, A. R., Ellis, I. O., Rakha, E. A. & Persson, J. L., 2019, In: Oncogene. 38, p. 375–389Research output: Contribution to journal › Journal article › Research › peer-review
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Rapid allergen-induced interleukin-17 and interferon-γ secretion by skin-resident memory CD8(+) T cells
Schmidt, J. D., Ahlström, M. G., Johansen, Jeanne Duus, Dyring-Andersen, Beatrice, Agerbeck, C., Nielsen, M. M., Poulsen, Steen Seier, Woetmann, Anders , Ødum, Niels, Thomsen, Allan Randrup, Geisler, Carsten & Bonefeld, Charlotte Menne, 2017, In: Contact Dermatitis. 76, 4, p. 218–227Research output: Contribution to journal › Journal article › Research › peer-review
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STAT3 dysregulation in mature T and NK cell lymphomas
Seffens, A., Herrera, A., Tegla, C., Buus, Terkild Brink, Hymes, K. B., Ødum, Niels, Geskin, L. J. & Koralov, S. B., 2019, In: Cancers. 11, 11, 17 p., 1711.Research output: Contribution to journal › Review › Research › peer-review
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Jak3, STAT3, and STAT5 inhibit expression of miR-22, a novel tumor suppressor microRNA, in cutaneous T-Cell lymphoma
Sibbesen, N. A., Kopp, K. L., Litvinov, I. V., Jønson, L., Willerslev-Olsen, A., Fredholm, S., Petersen, D. L., Nastasi, C., Krejsgaard, T., Lindahl, L. M., Gniadecki, R., Mongan, N. P., Sasseville, D., Wasik, M. A., Iversen, L., Bonefeld, Charlotte Menne, Geisler, Carsten, Woetmann, Anders & Ødum, Niels, 2015, In: OncoTarget. 6, 24, p. 20555-69 15 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Activation of Stat-3 is involved in the induction of apoptosis after ligation of major histocompatibility complex class I molecules on human Jurkat T cells
Skov, S., Nielsen, M., Bregenholt, S., Ødum, Niels & Claesson, Mogens Helweg, 1998, In: Blood. 91, 10, p. 3566-73 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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MHC class I signaling in T cells leads to tyrosine kinase activity and PLC-gamma 1 phosphorylation
Skov, S., Ødum, Niels & Claesson, Mogens Helweg, 1995, In: Journal of Immunology. 154, 3, p. 1167-76 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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IL-2 and IL-15 regulate CD154 expression on activated CD4 T cells
Skov, S., Bonyhadi, M., Ødum, Niels & Ledbetter, J. A., 2000, In: Journal of Immunology. 164, 7, p. 3500-5 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
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MHC class I ligation of human T cells activates the TYK-2 kinase and induces tyrosine phosphorylation, nuclear translocation, and DNA binding of the Stat3 transcription factor
Skov, Søren, Nielsen, M., Bregenholt, S., Ødum, Niels & Claesson, Mogens Helweg, 1998, In: Blood. 91, p. 3566-3573Research output: Contribution to journal › Journal article › Research › peer-review
ID: 14062
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Vitamin D up-regulates the vitamin D receptor by protecting it from proteasomal degradation in human CD4+ T cells
Research output: Contribution to journal › Journal article › Research › peer-review
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427
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Vitamin D counteracts Mycobacterium tuberculosis-induced cathelicidin downregulation in dendritic cells and allows Th1 differentiation and IFNγ secretion
Research output: Contribution to journal › Journal article › Research › peer-review
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351
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STAT5 induces miR-21 expression in cutaneous T cell lymphoma
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Published