Niels Ødum

Niels Ødum

Professor

Member of:


    1. Published

      Staphylococcal enterotoxins modulate interleukin 2 receptor expression and ligand-induced tyrosine phosphorylation of the Janus protein-tyrosine kinase 3 (Jak3) and signal transducers and activators of transcription (Stat proteins)

      Nielsen, M., Svejgaard, A., Röpke, C., Nordahl, M. & Ødum, Niels, 1995, In: Proceedings of the National Academy of Science of the United States of America. 92, 24, p. 10995-9 4 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    2. Published

      Interleukin-2 and -15 activate Stat 3a in human T lymphocytes

      Nielsen, M., Pedersen, M. N., Svejgaard, A. & Ødum, Niels, 1998, In: Cytokine. 10, p. 735-738

      Research output: Contribution to journalJournal articleResearch

    3. Published

      Spontaneous interleukin-5 production in cutaneous T-cell lymphoma lines is mediated by constitutively activated Stat3

      Nielsen, M., Nissen, Mogens Holst, Gerwien, J., Zocca, M., Rasmussen, H. M., Nakajima, K., Röpke, C., Geisler, Carsten, Kaltoft, K. & Ødum, Niels, 2002, In: Blood. 99, 3, p. 973-7 4 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    4. Published

      Interleukine-2 induces tyrosine phosphorylation and nuclear translocation of stat3 in human T lymphocytes

      Nielsen, M., Svejgaard, A., Skov, S. & Ødum, Niels, 1994, In: European Journal of Immunology. 12, p. 3082

      Research output: Contribution to journalJournal articleResearch

    5. Published

      IL-1β-Dependent Activation of Dendritic Epidermal T Cells in Contact Hypersensitivity

      Nielsen, M. M., Lovato, P., Macleod, A. S., Witherden, D. A., Skov, Lone, Dyring-Andersen, Beatrice, Dabelsteen, Sally, Woetmann, Anders , Ødum, Niels, Havran, W. L., Geisler, Carsten & Bonefeld, Charlotte Menne, 1 Apr 2014, In: Journal of immunology (Baltimore, Md. : 1950). 192, 7, p. 2975-83 9 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    6. Published

      NKG2D-Dependent Activation of Dendritic Epidermal T cells in Contact Hypersensitivity

      Nielsen, M. M., Dyring-Andersen, Beatrice, Schmidt, J. D., Witherden, D., Lovato, P., Woetmann, Anders , Ødum, Niels, Poulsen, Steen Seier, Havran, W. L., Geisler, Carsten & Bonefeld, Charlotte Menne, May 2015, In: Journal of Investigative Dermatology. 135, 5, p. 1311-19 9 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    7. Published

      Cytotoxicity of CD56bright NK cells towards autologous activated CD4+ T cells is mediated through NKG2D, LFA-1 and TRAIL and dampened via CD94/NKG2A

      Nielsen, N., Ødum, Niels, Ursø, B., Lanier, L. L. & Spee, P., 2012, In: PLoS ONE. 7, 2, 10 p., e31959.

      Research output: Contribution to journalJournal articleResearchpeer-review

    8. Published

      Clinical and histological characteristics of mycosis fungoides and sézary syndrome: A retrospective, single-centre study of 43 patients from eastern Denmark

      Nielsen, P. R., Eriksen, J. O., Wehkamp, U., Lindahl, L. M., Gniadecki, R., Fogh, H., Fabricius, S., Bzorek, M., Ødum, Niels & Gjerdrum, Lise Mette Rahbek, 2019, In: Acta Dermato-Venereologica. 99, 13, p. 1231-1236 6 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    9. Published

      Role of B-cells in mycosis fungoides

      Nielsen, Pia Rude, Eriksen, J. O., Sørensen, M. D., Wehkamp, U., Lindahl, L. M., Bzorek, M., Iversen, L., Woetmann, Anders , Ødum, Niels, Litman, Thomas & Gjerdrum, Lise Mette Rahbek, 2021, In: Acta Dermato-Venereologica. 101, 3, adv00413.

      Research output: Contribution to journalJournal articleResearchpeer-review

    10. Published

      Diagnostic Two-Gene Classifier in Early-Stage Mycosis Fungoides: A Retrospective Multicenter Study

      Nielsen, Pia Rude, Eriksen, J. O., Lindahl, L. M., Wehkamp, U., Bzorek, M., Andersen, G., Woetmann, Anders , Iversen, L., Ødum, Niels, Litman, Thomas & Gjerdrum, Lise Mette Rahbek, 2021, In: Journal of Investigative Dermatology. 141, 1, p. 213-217.e5

      Research output: Contribution to journalLetterResearchpeer-review

    11. Published

      MiR137 is an androgen regulated repressor of an extended network of transcriptional coregulators

      Nilsson, E. M., Laursen, K. B., Whitchurch, J., McWilliam, A., Ødum, Niels, Persson, J. L., Heery, D. M., Gudas, L. J. & Mongan, N. P., 2015, In: OncoTarget. 6, 34, p. 35710-35725 16 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    12. Published

      Omalizumab serum levels predict treatment outcomes in patients with chronic spontaneous urticaria: A three months prospective study

      Noshela Ghazanfar, M., Bartko, E. A., Arildsen, Nicolai Skovbjerg, Poulsen, Lars K., Jensen, B. M., Enevold, C., Holm, J. G., Woetmann, Anders , Ødum, Niels & Thomsen, Simon Francis, 2022, In: Clinical and Experimental Allergy. 52, 4 p.

      Research output: Contribution to journalComment/debateResearch

    13. Published

      Signal transduction by HLA-DR is mediated by tyrosine kinase(s) and regulated by CD45 in activated T cells

      Ødum, Niels, Martin, P. J., Schieven, G. L., Norris, N. A., Grosmaire, L. S., Hansen, J. A. & Ledbetter, J. A., 1991, In: Human Immunology. 32, 2, p. 85-94 9 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    14. Published

      MHC class II molecules deliver costimulatory signals in human T cells through a functional linkage with IL-2-receptors

      Ødum, Niels, Kanner, S. B., Ledbetter, J. A. & Svejgaard, A., 1993, In: Journal of Immunology. 150, 12, p. 5289-98 9 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    15. Published

      HLA-DR molecules enhance signal transduction through the CD3/Ti complex in activated T cells

      Ødum, Niels, Martin, P. J., Schieven, G. L., Masewicz, S., Hansen, J. A. & Ledbetter, J. A., 1991, In: HLA. 38, 2, p. 72-7 5 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    16. Published

      Homotypic aggregation of human cell lines by HLA class II-, class Ia- and HLA-G-specific monoclonal antibodies

      Ødum, Niels, Ledbetter, J. A., Martin, P., Geraghty, D., Tsu, T., Hansen, J. A. & Gladstone, P., 1991, In: European Journal of Immunology. 21, 9, p. 2121-31 10 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    17. Published

      Signal transduction by HLA class II molecules in human T cells: induction of LFA-1-dependent and independent adhesion

      Ødum, Niels, Yoshizumi, H., Okamoto, Y., Kamikawaji, N., Kimura, A., Nishimura, Y. & Sasazuki, T., 1992, In: Human Immunology. 35, 2, p. 71-84 13 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    18. Published
    19. Published

      Arne Svejgaard and immunogenetics in Denmark

      Ødum, Niels, Fugger, L. & Dickmeiss, E., 1997, In: HLA. 49, 3, p. 291-2 1 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    20. Published

      Effect of praziquantel on human lymphocyte proliferation in vitro

      Ødum, Niels, Theander, Thor Grundtvig & Bygbjerg, Ib Christian, 1984, In: European Journal of Clinical Pharmacology. 27, 3, p. 311-3 2 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    21. Published

      The CC-chemokine receptor 5 (CCR5) is a marker of, but not essential for the development of human Th1 cells

      Ødum, Niels, Bregenholt, S., Eriksen, K. W., Skov, S., Ryder, L. P., Bendtzen, K., Van Neerven, R. J., Svejgaard, A. & Garred, Peter, 1999, In: HLA. 54, 6, p. 572-7 6 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    22. Published

      IKca Channel Blocking compounds/immunosuppressiva

      Olesen, S., Jensen, B. S., Jørgensen, T. H., Strøbæk, D., Christoffersen, P. & Ødum, Niels, 1999, PCT.

      Research output: Book/ReportBookResearch

    23. Published

      Increased frequency of HLA-DR2 in patients with Darier's disease

      Oxholm, A., Oxholm, P., da Cunha Bang, F., Prause, J. U., Odum, N., Jakobsen, B. K., Svejgaard, A. & Ødum, Niels, 1990, In: British Journal of Dermatology. 123, 6, p. 845

      Research output: Contribution to journalJournal articleResearchpeer-review

    24. Published

      Endolysin Inhibits Skin Colonization by Patient-Derived Staphylococcus Aureus and Malignant T-Cell Activation in Cutaneous T-Cell Lymphoma

      Pallesen, E. M. H., Gluud, M., Vadivel, C. K., Buus, T. B., de Rooij, B., Zeng, Z., Ahmad, S., Willerslev-Olsen, A., Röhrig, C., Kamstrup, M. R., Bay, L., Lindahl, L., Krejsgaard, T., Geisler, C., Bonefeld, C. M., Iversen, L., Woetmann, A., Koralov, S. B., Bjarnsholt, T., Frieling, J. & 2 others, Schmelcher, M. & Ødum, Niels, 2023, In: Journal of Investigative Dermatology. 143, 9, p. 1757-1769 15 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    25. Published

      Selective modulation of the CD4 molecular complex by Pseudomonas aeruginosa alkaline protease and elastase

      Pedersen, Bente Klarlund, Kharazmi, A., Theander, Thor Grundtvig, Ødum, Niels, Andersen, V. & Bendtzen, K., 1987, In: Scandinavian Journal of Immunology. 26, 1, p. 91-4 3 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    26. Published

      Vascular endothelial growth factor receptor-3 expression in mycosis fungoides

      Pedersen, I. H., Willerslev-Olsen, A., Vetter-Kauczok, C., Krejsgaard, T., Lauenborg, B., Kopp, K. L., Geisler, Carsten, Bonefeld, Charlotte Menne, Zhang, Q., Wasik, M. A., Dabelsteen, Sally, Woetmann, Anders , Becker, J. C. & Ødum, Niels, 2012, In: Leukemia and Lymphoma.

      Research output: Contribution to journalJournal articleResearchpeer-review

    27. Published

      Phenotypic plasticity of malignant T cells in blood and skin of a Sézary syndrome patient revealed by single cell transcriptomics

      Peiffer, L., Gambichler, T., Buus, Terkild Brink, Horny, K., Gravemeyer, J., Furtmann, F., Spassova, I., Kubat, L., Susok, L., Stranzenbach, R., Srinivas, N., Ødum, Niels & Becker, J. C., 2023, In: Frontiers in Oncology. 13, 1090592.

      Research output: Contribution to journalJournal articleResearchpeer-review

    28. Published

      TGFβ-derived immune modulatory vaccine: targeting the immunosuppressive and fibrotic tumor microenvironment in a murine model of pancreatic cancer

      Perez Penco, Maria, Weis-Banke, S. E., Schina, A., Siersbæk, M., Hübbe, M. L., Jørgensen, M. A., Lecoq, I., Lara De La Torre, L., Bendtsen, S. K., Martinenaite, E., Holmström, M. O., Madsen, Daniel Hargbøl, dqp123, dqp123, Ødum, Niels, Grøntved, L. & Andersen, Mads Hald, 2022, In: Journal for ImmunoTherapy of Cancer. 10, 12, 15 p., e005491.

      Research output: Contribution to journalJournal articleResearchpeer-review

    29. Published

      B-lymphoid tyrosine kinase (Blk) is an oncogene and a potential target for therapy with Dasatinib in cutaneous T-cell lymphoma (CTCL)

      Petersen, D. L., Krejsgaard, T., Berthelsen, J., Fredholm, S., Willerslev-Olsen, A., Sibbesen, N. A., Bonefeld, Charlotte Menne, Andersen, M. H., Francavilla, C., Olsen, Jesper Velgaard, Hu, T., Zhang, M., Wasik, M. A., Geisler, Carsten, Woetmann, Anders & Ødum, Niels, 12 Jun 2014, In: Leukemia. 28, p. 2109-12 4 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    30. Published

      MICRORNA 203 CONTROLS T-CELL LYMPHOMAGENESIS BY TARGETING IL-2 RECEPTOR SIGNALING

      Ralfkiaer, U., Jansson, Martin David, Kopp, K., Willerslev-Olsen, A., Asmar, F., Krejsgaard, T., Brown, P., Gniadecki, R., Woetmann, Anders , Lund, Anders H., Ødum, Niels & Grønbæk, Kirsten, 22 Jun 2015, In: Haematologica. 100, supplement 1, p. 104-105 2 p., P317.

      Research output: Contribution to journalConference abstract in journalResearchpeer-review

    31. Published

      Diagnostic microRNA profiling in cutaneous T-cell lymphoma (CTCL)

      Ralfkiaer, U., Hagedorn, P., Bangsgaard, N., Løvendorf, M. B., Ahler, C. B., Svensson, L., Kopp, K. L., Vennegaard, M. T., Lauenborg, B., Zibert, J. R., Krejsgaard, T., Bonefeld, C. M., Søkilde, R., Gjerdrum, L. M., Labuda, T., Mathiesen, A-M., Grønbaek, K., Wasik, M. A., Sokolowska-Wojdylo, M., Queille-Roussel, C. & 9 others, Gniadecki, R., Ralfkiaer, E., Geisler, Carsten, Litman, Thomas, Woetmann, Anders , Glue, C., Røpke, M. A., Skov, Lone & Ødum, Niels, 2011, In: Blood. 118, 22, p. 5891-5900 10 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    32. Published

      MicroRNA expression in early mycosis fungoides is distinctly different from atopic dermatitis and advanced cutaneous T-cell lymphoma

      Ralfkiaer, U., Lindahl, L. M., Litman, Thomas, Gjerdrum, Lise Mette Rahbek, Ahler, C. B., Gniadecki, R., Marstrand, T., Fredholm, S., Iversen, L., Wasik, M. A., Bonefeld, Charlotte Menne, Geisler, Carsten, Krejsgaard, T., Glue, C., Røpke, M. A., Woetmann, A., Skov, Lone, Grønbæk, Kirsten & Ødum, Niels, Dec 2014, In: Anticancer Research. 34, 12, p. 7207-17 11 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    33. Published

      Proteasomal targeting and minigene repetition improve cell-surface presentation of a transfected, modified melanoma tumour antigen

      Rasmussen, A. B., Zocca, M., Bonefeld, Charlotte Menne, von Essen, Marina Rode, Lauritsen, J. P., Tomra, S., Ødum, Niels & Geisler, Carsten, 2004, In: Scandinavian Journal of Immunology. 59, 2, p. 220-7 7 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    34. Published

      Suppressed microRNA-195-5p expression in mycosis fungoides promotes tumor cell proliferation

      Rittig, A. H., Johansen, C., Celis, P., Ødum, Niels, Litman, Thomas, Woetmann, Anders , Lindahl, L. M. & Iversen, L., 2021, In: Experimental Dermatology. 30, 8, p. 1141-1149

      Research output: Contribution to journalJournal articleResearchpeer-review

    35. Published

      The microRNA expression profile differs between erythrodermic mycosis fungoides and Sézary syndrome

      Rittig, A. H., Lindahl, L. M., Johansen, C., Celis, P., Ødum, Niels, Iversen, L. & Litman, Thomas, 2019, In: Acta Dermato-Venereologica. 99, 12, p. 1148-1153 6 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    36. Published

      Vitamin D counteracts Mycobacterium tuberculosis-induced cathelicidin downregulation in dendritic cells and allows Th1 differentiation and IFNγ secretion

      Rode, A. K. O., Kongsbak-Wismann, Martin, Hansen, M. M., Lopez, D. V., Levring, T. B., Woetmann, Anders , Ødum, Niels, Bonefeld, Charlotte Menne & Geisler, Carsten, May 2017, In: Frontiers in Immunology. 8, 12 p., 656.

      Research output: Contribution to journalJournal articleResearchpeer-review

    37. Published

      Induced Human Regulatory T Cells Express the Glucagon-like Peptide-1 Receptor

      Rode, A. K. O., Buus, Terkild Brink, Mraz, Veronika, Al-Jaberi, F. A. H., Lopez, D. V., Ford, Shayne Lavondua, Hennen, S., Eliasen, I. P., Klewe, I. V., Gharehdaghi, L., Dragan, A., Rosenkilde, Mette, Woetmann, Anders , Skov, Lone, Ødum, Niels, Bonefeld, Charlotte Menne, Kongsbak-Wismann, Martin & Geisler, Carsten, 2022, In: Cells. 11, 16, 2587.

      Research output: Contribution to journalJournal articleResearchpeer-review

    38. Published

      Expression of full-length and splice forms of FoxP3 in rheumatoid arthritis

      Ryder, L. R., Woetmann, Anders , Madsen, H. O., Ødum, Niels, Ryder, L. P., Bliddal, H., Danneskiold-Samsøe, B., Ribel-Madsen, S., Bartels, E. M., Ryder, L. R., Danielsen, A. L. W., Madsen, H. O., Ødum, N., Ryder, L. P., Bliddal, Henning, Danneskiold-Samsøe, B., Ribel-Madsen, S. & Bartels, E. M., 1 Aug 2010, In: Scandinavian Journal of Rheumatology. 39, 4, p. 279-86 8 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    39. Published

      FoxP3 mRNA splice forms in synovial CD4+ T cells in rheumatoid arthritis and psoriatic arthritis

      Ryder, L. R., Bartels, E. M., Woetmann, Anders , Madsen, H. O., Ødum, Niels, Bliddal, H., Danneskiold-Samsøe, B., Ribel-Madsen, S. & Ryder, L. P., May 2012, In: APMIS : acta pathologica, microbiologica, et immunologica Scandinavica. 120, 5, p. 387-396 10 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    40. Published

      Differential effects of decoy receptor- and antibody-mediated tumour necrosis factor blockage on FoxP3 expression in responsive arthritis patients

      Ryder, L. R., Ryder, L. P., Bartels, E. M., Woetmann, Anders , Madsen, H. O., Ødum, Niels, Danneskiold-Samsøe, B., Ribel-Madsen, S. & Bliddal, Henning, Apr 2013, In: APMIS : acta pathologica, microbiologica, et immunologica Scandinavica. 121, 4, p. 337-47 11 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    41. Published

      Differential effects of decoy receptor- and antibody-mediated tumour necrosis factor blockage on FoxP3 expression in responsive arthritis patients

      Ryder, L. R., Ryder, L. P., Bartels, E. M., Woetmann, Anders , Madsen, H. O., Ødum, Niels, Danneskiold-Samsøe, B., Ribel-Madsen, S. & Bliddal, Henning, 2013, In: A P M I S. Acta Pathologica, Microbiologica et Immunologica Scandinavica. 121, 4, p. 337-347 11 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    42. Published

      Apoptosis following interleukin-2 withdrawal from T cells: evidence for a regulatory role of CD18 (beta 2-integrin) molecules

      Röpke, C., Gladstone, P., Nielsen, M., Borregaard, N., Ledbetter, J. A., Svejgaard, A. & Ødum, Niels, 1996, In: HLA. 48, 2, p. 127-35 8 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    43. Published

      The role of PIP5K1α/pAKT and targeted inhibition of growth of subtypes of breast cancer using PIP5K1α inhibitor

      Sarwar, M., Syed Khaja, A. S., Aleskandarany, M., Karlsson, R., Althobiti, M., Ødum, Niels, Mongan, N. P., Dizeyi, N., Johnson, H., Green, A. R., Ellis, I. O., Rakha, E. A. & Persson, J. L., 2019, In: Oncogene. 38, p. 375–389

      Research output: Contribution to journalJournal articleResearchpeer-review

    44. Published

      Rapid allergen-induced interleukin-17 and interferon-γ secretion by skin-resident memory CD8(+) T cells

      Schmidt, J. D., Ahlström, M. G., Johansen, Jeanne Duus, Dyring-Andersen, Beatrice, Agerbeck, C., Nielsen, M. M., Poulsen, Steen Seier, Woetmann, Anders , Ødum, Niels, Thomsen, Allan Randrup, Geisler, Carsten & Bonefeld, Charlotte Menne, 2017, In: Contact Dermatitis. 76, 4, p. 218–227

      Research output: Contribution to journalJournal articleResearchpeer-review

    45. Published

      STAT3 dysregulation in mature T and NK cell lymphomas

      Seffens, A., Herrera, A., Tegla, C., Buus, Terkild Brink, Hymes, K. B., Ødum, Niels, Geskin, L. J. & Koralov, S. B., 2019, In: Cancers. 11, 11, 17 p., 1711.

      Research output: Contribution to journalReviewResearchpeer-review

    46. Published

      Jak3, STAT3, and STAT5 inhibit expression of miR-22, a novel tumor suppressor microRNA, in cutaneous T-Cell lymphoma

      Sibbesen, N. A., Kopp, K. L., Litvinov, I. V., Jønson, L., Willerslev-Olsen, A., Fredholm, S., Petersen, D. L., Nastasi, C., Krejsgaard, T., Lindahl, L. M., Gniadecki, R., Mongan, N. P., Sasseville, D., Wasik, M. A., Iversen, L., Bonefeld, Charlotte Menne, Geisler, Carsten, Woetmann, Anders & Ødum, Niels, 2015, In: OncoTarget. 6, 24, p. 20555-69 15 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    47. Published

      Activation of Stat-3 is involved in the induction of apoptosis after ligation of major histocompatibility complex class I molecules on human Jurkat T cells

      Skov, S., Nielsen, M., Bregenholt, S., Ødum, Niels & Claesson, Mogens Helweg, 1998, In: Blood. 91, 10, p. 3566-73 7 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    48. Published

      MHC class I signaling in T cells leads to tyrosine kinase activity and PLC-gamma 1 phosphorylation

      Skov, S., Ødum, Niels & Claesson, Mogens Helweg, 1995, In: Journal of Immunology. 154, 3, p. 1167-76 9 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    49. Published

      IL-2 and IL-15 regulate CD154 expression on activated CD4 T cells

      Skov, S., Bonyhadi, M., Ødum, Niels & Ledbetter, J. A., 2000, In: Journal of Immunology. 164, 7, p. 3500-5 5 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    50. Published

      MHC class I ligation of human T cells activates the TYK-2 kinase and induces tyrosine phosphorylation, nuclear translocation, and DNA binding of the Stat3 transcription factor

      Skov, Søren, Nielsen, M., Bregenholt, S., Ødum, Niels & Claesson, Mogens Helweg, 1998, In: Blood. 91, p. 3566-3573

      Research output: Contribution to journalJournal articleResearchpeer-review

    ID: 14062