Carsten Geisler

Carsten Geisler

Professor

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    ORCID: 0000-0002-8472-0771

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    1. Published

      γδ T cells and inflammatory skin diseases

      Jee, Mia Hamilton, Mraz, Veronika, Geisler, Carsten & Bonefeld, Charlotte Menne, 2020, In: Immunological Reviews. 298, 1, p. 61-73

      Research output: Contribution to journal › Review › Research › peer-review

    2. Published

      beta2-adaptin is constitutively de-phosphorylated by serine/threonine protein phosphatase PP2A and phosphorylated by a staurosporine-sensitive kinase

      Lauritsen, J. P. H., Bonefeld, Charlotte Menne, Kastrup, J., Dietrich, J., Ødum, Niels & Geisler, Carsten, 2000, In: BBA General Subjects. 1497, 3, p. 297-307 10 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    3. Published

      Vitamin D-binding protein controls T cell responses to vitamin D

      Kongsbak-Wismann, Martin, von Essen, Marina Rode, Levring, T. B., Schjerling, Peter, Woetmann, A., Ødum, Niels, Bonefeld, Charlotte Menne & Geisler, Carsten, 2014, In: B M C Immunology. 15, p. 1-13 13 p., 35.

      Research output: Contribution to journal › Journal article › Research › peer-review

    4. Published

      Vitamin D up-regulates the vitamin D receptor by protecting it from proteasomal degradation in human CD4+ T cells

      Kongsbak-Wismann, Martin, von Essen, Marina Rode, Boding, L., Levring, T. B., Schjerling, Peter, Lauritsen, J. P. H., Woetmann, Anders , Ødum, Niels, Bonefeld, Charlotte Menne & Geisler, Carsten, 2014, In: PLOS ONE. 9, 5, p. 1-12 13 p., e96695.

      Research output: Contribution to journal › Journal article › Research › peer-review

    5. Published

      Vitamin D in Cutaneous T-Cell Lymphoma

      Ødum, A. W. F. & Geisler, Carsten, 2024, In: Cells. 13, 6, 19 p., 503.

      Research output: Contribution to journal › Review › Research › peer-review

    6. Published

      Vitamin D counteracts Mycobacterium tuberculosis-induced cathelicidin downregulation in dendritic cells and allows Th1 differentiation and IFNγ secretion

      Rode, A. K. O., Kongsbak-Wismann, Martin, Hansen, M. M., Lopez, D. V., Levring, T. B., Woetmann, Anders , Ødum, Niels, Bonefeld, Charlotte Menne & Geisler, Carsten, May 2017, In: Frontiers in Immunology. 8, 12 p., 656.

      Research output: Contribution to journal › Journal article › Research › peer-review

    7. Published

      Vitamin D controls T cell antigen receptor signaling and activation of human T cells

      von Essen, Marina Rode, Kongsbak-Wismann, Martin, Schjerling, Peter, Ølgaard, Klaus, Ødum, Niels & Geisler, Carsten, 2010, In: Nature Immunology. 11, 4, p. 344-349 5 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    8. Published

      Vitamin D Inhibits IL-22 Production Through a Repressive Vitamin D Response Element in the il22 Promoter

      Lopez, D. V., Al-Jaberi, F. A. H., Damas, N. D., Weinert, B. T., Pus, U., Torres-Rusillo, S., Woetmann, Anders , Ødum, Niels, Bonefeld, Charlotte Menne, Kongsbak-Wismann, Martin & Geisler, Carsten, 2021, In: Frontiers in Immunology. 12, 715059.

      Research output: Contribution to journal › Journal article › Research › peer-review

    9. Published

      Vascular endothelial growth factor receptor-3 expression in mycosis fungoides

      Pedersen, I. H., Willerslev-Olsen, A., Vetter-Kauczok, C., Krejsgaard, T., Lauenborg, B., Kopp, K. L., Geisler, Carsten, Bonefeld, Charlotte Menne, Zhang, Q., Wasik, M. A., Dabelsteen, Sally, Woetmann, Anders , Becker, J. C. & Ødum, Niels, 2012, In: Leukemia and Lymphoma.

      Research output: Contribution to journal › Journal article › Research › peer-review

    10. Published

      Validation of a diagnostic miRNA classifier in cutaneous T-cell lymphomas

      Marstrand, T., Ahler, C. B., Ralfkiaer, U., Clemmensen, A., Kopp, K. L., Sibbesen, N. A., Krejsgaard, T., Litman, Thomas, Wasik, M. A., Bonefeld, Charlotte Menne, Grønbæk, Kirsten, Gjerdum, L. M. R., Gniadecki, R., Ralfkiaer, E., Geisler, Carsten, Woetmann, Anders , Røpke, M. A., Glue, C., Skov, Lone & Ødum, Niels, 2014, In: Leukemia and Lymphoma. 55, 4, p. 957-958 2 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    11. Published

      Two distinct pathways exist for down-regulation of the TCR

      Lauritsen, J. P., Bartels, Mette Damkjær, Dietrich, J., Kastrup, J., Odum, N. & Geisler, Carsten, 1998, In: Journal of Immunology. 161, 1, p. 260-7 7 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    12. Published

      Tumor necrosis factor induces rapid down-regulation of TXNIP in human T cells

      Levring, T. B., Kongsbak-Wismann, Martin, Rode, A. K. O., Al-Jaberi, F. A. H., Lopez, D. V., Met, Özcan, Woetmann, Anders , Bonefeld, Charlotte Menne, Ødum, Niels & Geisler, Carsten, 2019, In: Scientific Reports. 9, 13 p., 16725.

      Research output: Contribution to journal › Journal article › Research › peer-review

    13. Published

      Transmembrane signalling via HLA-DR molecules on T cells from a Sezary T-cell leukaemia line

      Geisler, Carsten, Kuhlmann, J., Møller, T., Plesner, T. & Rubin, B., 1990, In: Scandinavian Journal of Immunology. 32, 6, p. 731-5 4 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    14. Published

      Three distinct developmental pathways for adaptive and two IFN-γ-producing γδ T subsets in adult thymus

      Buus, Terkild Brink, Ødum, Niels, Geisler, Carsten & Lauritsen, J. P. H., 4 Dec 2017, In: Nature Communications. 8, 1911, 13 p., 1911.

      Research output: Contribution to journal › Journal article › Research › peer-review

    15. Published

      The vitamin d receptor and T cell function

      Kongsbak-Wismann, Martin, Levring, T. B., Geisler, Carsten & von Essen, Marina Rode, 2013, In: Frontiers in Immunology. 4, p. 148 10 p., 148.

      Research output: Contribution to journal › Journal article › Research › peer-review

    16. Published

      The role of the different CD3γ domains in TCR expression and signaling

      Garcillán, B., Megino, R. F., Herrero-Alonso, M., Guardo, A. C., Perez-Flores, V., Juraske, C., Idstein, V., Martin-Fernandez, J. M., Geisler, Carsten, Schamel, W. W. A., Marin, A. V. & Regueiro, J. R., 2022, In: Frontiers in Immunology. 13, 978658.

      Research output: Contribution to journal › Journal article › Research › peer-review

    17. Published

      The role of interleukin-1β in the immune response to contact allergens

      Yeung, Kelvin, Mraz, Veronika, Geisler, Carsten, Skov, Lone & Bonefeld, Charlotte Menne, 2021, In: Contact Dermatitis. 85, 4, p. 387-397

      Research output: Contribution to journal › Review › Research › peer-review

    18. Published

      The role of innate lymphoid cells in healthy and inflamed skin

      Bonefeld, Charlotte Menne & Geisler, Carsten, Nov 2016, In: Immunology Letters. 179, p. 25-28

      Research output: Contribution to journal › Letter › Research › peer-review

    19. Published

      The role of caspase 3 and BclxL in the action of interleukin 7 (IL-7): a survival factor in activated human T cells

      Amos, C. L., Woetmann, Anders , Nielsen, M., Geisler, Carsten, Odum, N., Brown, B. L. & Dobson, P. R., 1998, In: Cytokine. 10, 9, p. 662-8 6 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    20. Published

      The phosphorylation state of CD3gamma influences T cell responsiveness and controls T cell receptor cycling

      Dietrich, J., Bäckström, T., Lauritsen, J. P., Kastrup, J., Bartels, Mette Damkjær, von Bülow, F., Palmer, E. & Geisler, Carsten, 1998, In: Journal of Biological Chemistry. 273, 37, p. 24232-8 6 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    21. Published

      The phosphatase domains of CD45 are required for ligand induced T-cell receptor downregulation

      Kastrup, J., Lauritsen, J. P. H., Bonefeld, Charlotte Menne, Dietrich, J. & Geisler, Carsten, 2000, In: Scandinavian Journal of Immunology. 51, 5, p. 491-6 5 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    22. Published

      The major diversification of Vγ1.1+ and Vγ2+ thymocytes in mice occurs after commitment to the γδ T-cell lineage

      Buus, Terkild Brink, Geisler, Carsten & Lauritsen, J. P. H., 11 Oct 2016, In: European Journal of Immunology. 46, 10, p. 2363-2375 13 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    23. Published

      The junctional adhesion molecule-like protein (JAML) is important for the inflammatory response during contact hypersensitivity

      Mraz, Veronika, Lohmann, R. K. D., Menzel, Mandy, Hawkes, A., Vaher, Helen, Funch, Anders Boutrup, Jee, Mia Hamilton, Gadsbøll, A. S. Ø., Weber, Julie Friis, Yeung, Kelvin, Ødum, Niels, Woetmann, Anders , McKay, D., Witherden, D., Geisler, Carsten & Bonefeld, Charlotte Menne, 2023, In: Contact Dermatitis. 89, 5, p. e63-e65

      Research output: Contribution to journal › Journal article › Research › peer-review

    24. Published

      The indispensable CD2-CD3 molecules: a key to T-cell differentiation and functional activation

      Rubin, B., Geisler, Carsten, Caspar, S. & Arnaud, J., 1992, In: Scandinavian Journal of Immunology. 36, 1, p. 1-6 5 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    25. Published

      The immunological synapse

      Klemmensen, T., Pedersen, L. O. & Geisler, Carsten, 2003, In: Archivum Immunologiae et Therapiae Experimentalis. 51, 6, p. 377-88 11 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    26. Published

      The effect of short-chain fatty acids on human monocyte-derived dendritic cells

      Nastasi, C., Candela, M., Bonefeld, Charlotte Menne, Geisler, Carsten, Hansen, M., Krejsgaard, T., Biagi, E., Andersen, Mads Hald, Brigidi, P., Ødum, Niels, Litman, T. & Woetmann, Anders , 2015, In: Scientific Reports. 5, 10 p., 16148.

      Research output: Contribution to journal › Journal article › Research › peer-review

    27. Published

      The cytoplasmic tail of FcgammaRIIIAalpha is involved in signaling by the low affinity receptor for immunoglobulin G

      Hou, X., Dietrich, J. & Geisler, Carsten, 1996, In: Journal of Biological Chemistry. 271, 37, p. 22815-22 7 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    28. Published

      The combination of IL-21 and IFN-alpha boosts STAT3 activation, cytotoxicity and experimental tumor therapy

      Eriksen, K. W., Søndergaard, H., Woetmann, Anders , Krejsgaard, T., Skak, K., Geisler, Carsten, Wasik, M. A. & Odum, N., 2008, In: Molecular Immunology. 46, 5, p. 812-20 8 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    29. Published

      The adjuvant mechanism of cationic dimethyldioctadecylammonium liposomes

      Korsholm, K. S., Agger, E. M., Foged, Camilla, Christensen, D., Dietrich, J., Andersen, C. S., Geisler, Carsten & Andersen, P., 2007, In: Immunology. 121, 2, p. 216-26 10 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    30. Published

      The Vitamin D Analogue Calcipotriol Reduces the Frequency of CD8+IL-17+ T Cells in Psoriasis Lesions

      Dyring-Andersen, Beatrice, Bonefeld, Charlotte Menne, Bzorek, M., Løvendorf, M. B., Lauritsen, J. P. H., Skov, Lone & Geisler, Carsten, Jul 2015, In: Scandinavian Journal of Immunology. 82, 1, p. 84-91 8 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    31. Published

      The Thioredoxin-Interacting Protein TXNIP Is a Putative Tumour Suppressor in Cutaneous T-Cell Lymphoma

      Stolearenco, V., Levring, T. B., Nielsen, H. M., Lindahl, L., Fredholm, S., Kongsbak-Wismann, Martin, Willerslev-Olsen, A., Buus, Terkild Brink, Nastasi, C., Hu, T., Gluud, Maria, Côme, Christophe Roger Michel, Krejsgaard, T., Iversen, L., Bonefeld, Charlotte Menne, Grønbæk, Kirsten, Met, Özcan, Woetmann, Anders , Ødum, Niels & Geisler, Carsten, 2021, In: Dermatology. 237, 2, p. 283-290 8 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    32. Published

      The T cell receptor. Structural and functional studies

      Geisler, Carsten, 1995, In: Danish Medical Bulletin. 42, 4, p. 342-57 15 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    33. Published

      The Expression of IL-21 Is Promoted by MEKK4 in Malignant T Cells and Associated with Increased Progression Risk in Cutaneous T-Cell Lymphoma

      Fredholm, S., Litvinov, I. V., Mongan, N. P., Schiele, S., Willerslev-Olsen, A., Petersen, D. L., Krejsgaard, T., Sibbesen, N., Nastasi, C., Bonefeld, Charlotte Menne, Persson, J. L., thor Straten, E. P., Andersen, Mads Hald, Koralov, S. B., Wasik, M. M., Geisler, Carsten, Sasseville, D., Woetmann, Anders & Ødum, Niels, 2016, In: Journal of Investigative Dermatology. 136, 4, p. 866-869 4 p.

      Research output: Contribution to journal › Comment/debate › Research › peer-review

    34. Published

      The CD3 gamma leucine-based receptor-sorting motif is required for efficient ligand-mediated TCR down-regulation

      von Essen, Marina Rode, Bonefeld, Charlotte Menne, Nielsen, B. L., Lauritsen, J. P. H., Dietrich, J., Andersen, P. S., Karjalainen, K., Ødum, Niels & Geisler, Carsten, 2002, In: Journal of Immunology. 168, 9, p. 4519-23 4 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    35. Published

      TCR¿ is transported to and retained in the Golgi apparatus independently of other TCR chains: implications for TCR assembly

      Dietrich, J., Kastrup, J., Lauritsen, J. P. H., Bonefeld, Charlotte Menne, von Bülow, F. & Geisler, Carsten, 1999, In: European Journal of Immunology. 29, 5, p. 1719-28 9 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    36. Published

      TCR trafficking in resting and stimulated T cells

      Geisler, Carsten, 2004, In: Critical Reviews in Immunology. 24, 1, p. 67-86 19 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    37. Published

      TCR down-regulation controls virus-specific CD8+ T cell responses

      Bonefeld, Charlotte Menne, Haks, M., Nielsen, B., von Essen, Marina Rode, Boding, L., Hansen, A. K., Larsen, J. M., Ødum, Niels, Krimpenfort, P., Kruisbeek, A., Christensen, Jan Pravsgaard, Thomsen, Allan Randrup & Geisler, Carsten, 1 Dec 2009, In: Journal of Immunology. 181, 11, p. 7786-7799 14 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    38. Published

      TCR down-regulation controls T cell homeostasis

      Boding, L., Bonefeld, Charlotte Menne, Nielsen, B. L., Lauritsen, J. P. H., von Essen, Marina Rode, Hansen, A. K., Larsen, J. M., Nielsen, M. M., Ødum, Niels & Geisler, Carsten, 2009, In: Journal of Immunology. 183, 8, p. 4994-5005 11 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    39. Published

      TCR down-regulation boosts T-cell-mediated cytotoxicity and protection against poxvirus infections

      Hansen, A. K., Regner, M., Bonefeld, Charlotte Menne, Boding, L., Kongsbak-Wismann, Martin, Ødum, Niels, Müllbacher, A., Geisler, Carsten & von Essen, Marina Rode, 2011, In: European Journal of Immunology. 41, 7, p. 1948-1957 10 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    40. Published

      TCR comodulation of nonengaged TCR takes place by a protein kinase C and CD3 gamma di-leucine-based motif-dependent mechanism

      Bonefeld, Charlotte Menne, Rasmussen, B. A., Lauritsen, J. P., von Essen, Marina Rode, Ødum, Niels, Andersen, P. S. & Geisler, Carsten, 2003, In: Journal of Immunology. 171, 6, p. 3003-9 6 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    41. Published

      TCR alpha beta chains associate with the plasma membrane independently of CD3 and TCR zeta chains in murine primary T cells

      Zhang, J., Salojin, K., Gao, J. X., Cameron, M., Geisler, Carsten & Delovitch, T. L., 1998, In: Journal of Immunology. 161, 6, p. 2930-7 7 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    42. Published

      T-cell receptor downregulation by ceramide-induced caspase activation and cleavage of the zeta chain

      Bonefeld, Charlotte Menne, Lauritsen, J. P. H., Dietrich, J., Kastrup, J., Wegener, A. K., Andersen, P. S., Odum, N. & Geisler, Carsten, 2001, In: Scandinavian Journal of Immunology. 53, 2, p. 176-83 7 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    43. Published

      T-cell activation. V. Anti-major histocompatibility complex class I antibody-induced activation and clonal abortion in Jurkat T-leukaemic cells

      Claesson, Mogens Helweg, Dissing, Steen, Tscherning, T. & Geisler, Carsten, 1993, In: Immunology. 78, 3, p. 444-8 4 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    44. Published

      T cell receptor zeta allows stable expression of receptors containing the CD3gamma leucine-based receptor-sorting motif

      Dietrich, J. & Geisler, Carsten, 1998, In: Journal of Biological Chemistry. 273, 41, p. 26281-4 3 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    45. Published

      T cell activation. II. Activation of human T lymphoma cells by cross-linking of their MHC class I antigens

      Dissing, Steen, Geisler, Carsten, Rubin, B., Plesner, T. & Claesson, Mogens Helweg, 1990, In: Cellular Immunology. 126, 1, p. 196-210 14 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    46. Published

      Substoichiometric ribose methylations in spliceosomal snRNAs

      Krogh, Nicolai, Kongsbak-Wismann, Martin, Geisler, Carsten & Nielsen, Henrik, 2017, In: Organic and Biomolecular Chemistry. 15, 42, p. 8872-8876 5 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    47. Published

      Structure of the T-cell receptor in a Ti alpha beta, Ti gamma delta double positive T-cell line

      Kuhlmann, J. & Geisler, Carsten, 1993, In: Scandinavian Journal of Immunology. 37, 2, p. 271-5 4 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    48. Published

      Structure of the T cell receptor in a Ti alpha V beta 2, alpha V beta 8-positive T cell line

      Hou, X., Dietrich, J., Kuhlmann, J., Wegener, A. M. & Geisler, Carsten, 1994, In: European Journal of Immunology. 24, 5, p. 1228-33 5 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    49. Published

      Structural mutations of C-domains in members of the Ig superfamily. Consequences for the interactions between the T cell antigen receptor and the zeta 2 homodimer

      Geisler, Carsten, Rubin, B., Caspar-Bauguil, S., Champagne, E., Vangsted, A., Hou, X. & Gajhede, Michael, 1992, In: Journal of Immunology. 148, 11, p. 3469-77 8 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    50. Published

      Staphylococcus enterotoxin A modulates interleukin 15-induced signaling and mitogenesis in human T cells

      Gerwien, J., Kaltoft, K., Nielsen, M., Nielsen, M. B., Svejgaard, A., Geisler, Carsten, Röpke, C. & Odum, N., 1998, In: HLA. 51, 2, p. 164-73 9 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

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