Carsten Geisler

Carsten Geisler

Professor

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    ORCID: 0000-0002-8472-0771

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    1. Published

      Impaired Vitamin D Signaling in T Cells From a Family With Hereditary Vitamin D Resistant Rickets

      Al-Jaberi, F. A. H., Kongsbak-Wismann, Martin, Aguayo-Orozco, A., Krogh, Nicolai, Buus, Terkild Brink, Lopez, D. V., Rode, A. K. O., Gravesen, Eva, Ølgaard, Klaus, Brunak, Søren, Woetmann, Anders , Ødum, Niels, Bonefeld, Charlotte Menne & Geisler, Carsten, 2021, In: Frontiers in Immunology. 12, 11 p., 684015.

      Research output: Contribution to journal › Journal article › Research › peer-review

    2. Published

      Reduced vitamin D-induced cathelicidin production and killing of Mycobacterium tuberculosis in macrophages from a patient with a non-functional vitamin D receptor: A case report

      Al-Jaberi, F. A. H., Crone, C. G., Lindenstrøm, T., Arildsen, Nicolai Skovbjerg, Lindeløv, E. S., Aagaard, L., Gravesen, E., Mortensen, R., Andersen, A. B., Ølgaard, Klaus, Hjaltelin, Jessica Xin, Brunak, Søren, Bonefeld, Charlotte Menne, Kongsbak-Wismann, Martin & Geisler, Carsten, 2022, In: Frontiers in Immunology. 13, 9 p., 1038960.

      Research output: Contribution to journal › Journal article › Research › peer-review

    3. Published

      The role of caspase 3 and BclxL in the action of interleukin 7 (IL-7): a survival factor in activated human T cells

      Amos, C. L., Woetmann, Anders , Nielsen, M., Geisler, Carsten, Odum, N., Brown, B. L. & Dobson, P. R., 1998, In: Cytokine. 10, 9, p. 662-8 6 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    4. Published

      A response calculus for immobilized T cell receptor ligands

      Andersen, P. S., Bonefeld, Charlotte Menne, Mariuzza, R. A., Geisler, Carsten & Karjalainen, K., 2001, In: Journal of Biological Chemistry. 276, 52, p. 49125-32 7 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    5. Published

      Role of the T cell receptor ligand affinity in T cell activation by bacterial superantigens

      Andersen, P. S., Geisler, Carsten, Buus, Søren, Mariuzza, R. A. & Karjalainen, K., 2001, In: Journal of Biological Chemistry. 276, 36, p. 33452-7 5 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    6. Published

      Quantifying the energetics of cooperativity in a ternary protein complex

      Andersen, P. S., Schuck, P., Sundberg, E. J., Geisler, Carsten, Karjalainen, K. & Mariuzza, R. A., 2002, In: Biochemistry. 41, 16, p. 5177-84 7 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    7. Published

      Ectopic expression of a novel CD22 splice-variant regulates survival and proliferation in malignant T cells from cutaneous T cell lymphoma (CTCL) patients

      Bagdonaite, Ieva , Wandall, Hans H., Litvinov, I. V., Nastasi, C., Becker, J. C., Dabelsteen, Sally, Geisler, Carsten, Bonefeld, Charlotte Menne, Zhang, Q., Wasik, M. A., Zhou, Y., Sasseville, D., Ødum, Niels & Woetmann, A., 2015, In: OncoTarget. 6, 16, p. 14374-14384 11 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    8. Published

      Idiopathic orthostatic hypotension

      Bartram, R., Petersen, P., Kastrup, J. & Geisler, Carsten, 1984, In: Ugeskrift for læger. 146, 2, p. 87-90 3 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    9. Published

      Biosynthesis of Tcr-alpha, beta and Tcr-gamma, delta/CD3 complexes

      Bauguil-Caspar, S., Arnaud, J., Kuhlmann, J., Geisler, Carsten & Rubin, B., 1993, In: Immunodeficiency. 4, 1-4, p. 113-6 3 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    10. Published

      Staphylococcal alpha-toxin tilts the balance between malignant and non-malignant CD4+ T cells in cutaneous T-cell lymphoma

      Blümel, E., Willerslev-Olsen, A., Gluud, Maria, Lindahl, L. M., Fredholm, S., Nastasi, C., Krejsgaard, T., Surewaard, B. G. J., Koralov, S. B., Hu, T., Persson, J. L., Bonefeld, Charlotte Menne, Geisler, Carsten, Iversen, L., Becker, J. C., Andersen, Mads Hald, Woetmann, Anders , Buus, Terkild Brink & Ødum, Niels, 2019, In: OncoImmunology. 8, 11, 7 p., e1641387.

      Research output: Contribution to journal › Journal article › Research › peer-review

    11. Published

      Staphylococcus aureus alpha-toxin inhibits CD8+ T cell-mediated killing of cancer cells in cutaneous T-cell lymphoma

      Blümel, E., Munir Ahmad, S., Nastasi, C., Willerslev-Olsen, A., Gluud, M., Fredholm, S., Hu, T., Surewaard, B. G. J., Lindahl, L. M., Fogh, H., Koralov, S. B., Rahbek Gjerdrum, L. M., Clark, R. A., Iversen, L., Krejsgaard, T., Bonefeld, C. M., Geisler, C., Becker, J. C., Woetmann, A., Andersen, M. H. & 2 others, Buus, Terkild Brink & Ødum, Niels, 2020, In: OncoImmunology. 9, 1, 9 p., 1751561.

      Research output: Contribution to journal › Journal article › Research › peer-review

    12. Published

      Midline 1 controls polarization and migration of murine cytotoxic T cells

      Boding, L., Hansen, A. K., Nielsen, M. M., Meroni, G., Braunstein, T. H., Woetmann, A., Ødum, Niels, Bonefeld, Charlotte Menne & Geisler, Carsten, Dec 2014, In: Immunity, Inflammation and Disease. 2, 4, p. 262-71 10 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    13. Published

      TCR down-regulation controls T cell homeostasis

      Boding, L., Bonefeld, Charlotte Menne, Nielsen, B. L., Lauritsen, J. P. H., von Essen, Marina Rode, Hansen, A. K., Larsen, J. M., Nielsen, M. M., Ødum, Niels & Geisler, Carsten, 2009, In: Journal of Immunology. 183, 8, p. 4994-5005 11 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    14. Published

      Polymorphisms of the T cell receptor CD3delta and CD3varepsilon chains affect anti-CD3 antibody binding and T cell activation

      Boding, L., Nielsen, M. W., Bonefeld, Charlotte Menne, von Essen, Marina Rode, Nielsen, B. L., Lauritsen, J. P. H., Hansen, A. K., Nielsen, M. M., Kongsbak, M., Rubin, M., Vennegaard, M. T., Ødum, Niels & Geisler, Carsten, 2010, In: Molecular Immunology. 47, 15, p. 2450-7 7 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    15. Published

      MID2 can substitute for MID1 and control exocytosis of lytic granules in cytotoxic T cells

      Boding, L., Hansen, A. K., Meroni, G., Levring, T. B., Woetmann, Anders , Ødum, Niels, Bonefeld, Charlotte Menne & Geisler, Carsten, Aug 2015, In: APMIS : acta pathologica, microbiologica, et immunologica Scandinavica. 123, 8, p. 682-7 6 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    16. Published

      Midline 1 directs lytic granule exocytosis and cytotoxicity of mouse killer T cells

      Boding, L., Hansen, A. K., Meroni, G., Johansen, B. B., Braunstein, T. H., Bonefeld, Charlotte Menne, Kongsbak-Wismann, Martin, Jensen, Benjamin Anderschou Holbech, Woetmann, A., Thomsen, Allan Randrup, Ødum, Niels, von Essen, Marina Rode & Geisler, Carsten, 12 Jul 2014, In: European Journal of Immunology. 44, 10, p. 3109-3118 10 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    17. Published

      Epidermal filaggrin deficiency mediates increased systemic T-helper 17 immune response

      Bonefeld, Charlotte Menne, Petersen, T. H., Bandier, J., Agerbeck, C., Linneberg, Allan René, Ross-Hansen, K., Stender, S., Szecsi, P. B., Johansen, Jeanne Duus, Geisler, Carsten & Thyssen, Jacob Pontoppidan, 1 Oct 2016, In: British Journal of Dermatology. 175, 4, p. 706-712 7 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    18. Published

      The role of innate lymphoid cells in healthy and inflamed skin

      Bonefeld, Charlotte Menne & Geisler, Carsten, Nov 2016, In: Immunology Letters. 179, p. 25-28

      Research output: Contribution to journal › Letter › Research › peer-review

    19. Published

      Immunological, chemical and clinical aspects of exposure to mixtures of contact allergens

      Bonefeld, Charlotte Menne, Geisler, Carsten, Gimenéz-Arnau, E., Lepoittevin, J. P., Uter, W. & Johansen, Jeanne Duus, 2017, In: Contact Dermatitis. 77, 3, p. 133-142 10 p.

      Research output: Contribution to journal › Review › Research › peer-review

    20. Published

      Consumer available permanent hair dye products cause major allergic immune activation in an animal model

      Bonefeld, Charlotte Menne, Larsen, J. M., Dabelsteen, Sally, Geisler, Carsten, White, I. R., Menne, T. & Johansen, Jeanne Duus, 2010, In: British Journal of Dermatology. 162, 1, p. 102-107 6 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    21. Published

      Nickel acts as an adjuvant during cobalt sensitization

      Bonefeld, Charlotte Menne, Nielsen, M. M., Vennegaard, M. T., Johansen, Jeanne Duus, Geisler, Carsten & Thyssen, Jacob Pontoppidan, Mar 2015, In: Experimental Dermatology. 24, 3, p. 229-231 3 p.

      Research output: Contribution to journal › Comment/debate › Research › peer-review

    22. Published

      Enhanced sensitization and elicitation responses caused by mixtures of common fragrance allergens

      Bonefeld, Charlotte Menne, Nielsen, M. M., Rubin, I. M. C., Vennegaard, M. T., Dabelsteen, Sally, Gimenéz-Arnau, E., Lepoittevin, J., Geisler, Carsten & Johansen, Jeanne Duus, Dec 2011, In: Contact Dermatitis. 65, 6, p. 336-342 7 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    23. Published

      TCR down-regulation controls virus-specific CD8+ T cell responses

      Bonefeld, Charlotte Menne, Haks, M., Nielsen, B., von Essen, Marina Rode, Boding, L., Hansen, A. K., Larsen, J. M., Ødum, Niels, Krimpenfort, P., Kruisbeek, A., Christensen, Jan Pravsgaard, Thomsen, Allan Randrup & Geisler, Carsten, 1 Dec 2009, In: Journal of Immunology. 181, 11, p. 7786-7799 14 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    24. Published

      TCR comodulation of nonengaged TCR takes place by a protein kinase C and CD3 gamma di-leucine-based motif-dependent mechanism

      Bonefeld, Charlotte Menne, Rasmussen, B. A., Lauritsen, J. P., von Essen, Marina Rode, Ødum, Niels, Andersen, P. S. & Geisler, Carsten, 2003, In: Journal of Immunology. 171, 6, p. 3003-9 6 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    25. Published

      An immune response study of oakmoss absolute and its constituents atranol and chloroatranol

      Bonefeld, Charlotte Menne, Nielsen, M. M., Gimenéz-Arnau, E., Lang, M., Vennegaard, M. T., Geisler, Carsten, Johansen, Jeanne Duus & Lepoittevin, J., 2014, In: Contact Dermatitis. 70, 5, p. 282-290 9 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    26. Published

      Contact allergens in African countries: A review of published patch test studies

      Bonefeld, N. M., Menné, T., Ahrensbøll-Friis, U., Gadsbøll, A. S. Ø., Wang, Christian William, Theander, Thor Grundtvig, Masenga, E. J., Mavura, D., Ødum, Niels, Bonefeld, Charlotte Menne & Geisler, Carsten, 2024, In: Contact Dermatitis. 90, 2, p. 103-109

      Research output: Contribution to journal › Review › Research › peer-review

    27. Published

      Constitutive SOCS-3 expression protects T-cell lymphoma against growth inhibition by IFNalpha

      Brender, C., Lovato, P., Sommer, V. H., Woetmann, Anders , Mathiesen, A., Geisler, Carsten, Wasik, M. & Ødum, Niels, 2005, In: Leukemia. 19, 2, p. 209-13 4 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    28. Published

      Interferon-alpha induces transient suppressors of cytokine signalling expression in human T cells

      Brender, C., Nielsen, M., Röpke, C., Nissen, M. H., Svejgaard, A., Billestrup, N., Geisler, Carsten & Ødum, Niels, 2001, In: Experimental and Clinical Immunogenetics. 18, 2, p. 80-5 5 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    29. Published

      Lck is involved in interleukin-2 induced proliferation but not cell survival in human T cells through a MAP kinase-independent pathway

      Brockdorff, J., Nielsen, M., Kaltoft, K., Mustelin, T., Röpke, C., Svejaard, A., Geisler, Carsten & Odum, N., 2000, In: European Cytokine Network. 11, 2, p. 225-31 6 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    30. Published

      Protein phosphatase 2A plays a critical role in interleukin-2-induced beta 2-integrin dependent homotypic adhesion in human CD4+ T cell lines

      Brockdorff, J., Nielsen, M., Svejgaard, A., Dobson, P., Röpke, C., Geisler, Carsten & Odum, N., 1997, In: Cytokine. 9, 5, p. 333-9 6 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    31. Published

      Interleukin 2 induces a transient downregulation of protein phosphatase 1 and 2A activity in human T cells

      Brockdorff, J., Nielsen, M., Dobson, P., Geisler, Carsten, Röpke, C., Svejgaard, A. & Odum, N., 1997, In: HLA. 49, 3 Pt 1, p. 228-35 7 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    32. Published

      Interleukin-2 induces beta2-integrin-dependent signal transduction involving the focal adhesion kinase-related protein B (fakB)

      Brockdorff, J., Kanner, S. B., Nielsen, M., Borregaard, N., Geisler, Carsten, Svejgaard, A. & Odum, N., 1998, In: Proceedings of the National Academy of Science of the United States of America. 95, 12, p. 6959-64 5 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    33. Published

      Gab2 is phosphorylated on tyrosine upon interleukin-2/interleukin-15 stimulation in mycosis-fungoides-derived tumor T cells and associates inducibly with SHP-2 and Stat5a

      Brockdorff, J. L., Gu, H., Mustelin, T., Kaltoft, K., Geisler, Carsten, Röpke, C. & Ødum, Niels, 2001, In: Experimental and Clinical Immunogenetics. 18, 2, p. 86-95 9 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    34. Published

      The major diversification of Vγ1.1+ and Vγ2+ thymocytes in mice occurs after commitment to the γδ T-cell lineage

      Buus, Terkild Brink, Geisler, Carsten & Lauritsen, J. P. H., 11 Oct 2016, In: European Journal of Immunology. 46, 10, p. 2363-2375 13 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    35. Published

      Single-cell heterogeneity in Sézary syndrome.

      Buus, Terkild Brink, Willerslev-Olsen, A., Fredholm, S. M., Blümel, E., Nastasi, C., Gluud, Maria, Hu, T., Lindahl, L. M., Iversen, L., Fogh, H., Gniadecki, R., Litvinov, I. V., Persson, J. L., Bonefeld, Charlotte Menne, Geisler, Carsten, Christensen, Jan Pravsgaard, Krejsgaard, T. F., Litman, Thomas, Woetmann, Anders & Ødum, Niels, 2018, In: Blood advances. 2, 16, p. 2115-2126

      Research output: Contribution to journal › Journal article › Research › peer-review

    36. Published

      Development of interleukin-17-producing Vγ2+ γδ T cells is reduced by ICOS signaling in the thymus

      Buus, Terkild Brink, Schmidt, J. D., Bonefeld, Charlotte Menne, Geisler, Carsten & Lauritsen, J. P. H., 29 Mar 2016, In: OncoTarget. 7, 15, p. 19341-19354 14 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    37. Published

      Three distinct developmental pathways for adaptive and two IFN-γ-producing γδ T subsets in adult thymus

      Buus, Terkild Brink, Ødum, Niels, Geisler, Carsten & Lauritsen, J. P. H., 4 Dec 2017, In: Nature Communications. 8, 1911, 13 p., 1911.

      Research output: Contribution to journal › Journal article › Research › peer-review

    38. Published

      A highly conserved phenylalanine in the alpha, beta-T cell receptor (TCR) constant region determines the integrity of TCR/CD3 complexes

      Caspar-Bauguil, S., Arnaud, J., Huchenq, A., Hein, W. R., Geisler, Carsten & Rubin, B., 1994, In: Scandinavian Journal of Immunology. 40, 3, p. 323-36 13 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    39. Published

      Functionally important amino acids in the TCR revealed by immunoselection of membrane TCR-negative T cells

      Caspar-Bauguil, S., Arnaud, J., Gouaillard, C., Hou, X., Geisler, Carsten & Rubin, B., 1994, In: Journal of Immunology. 152, 11, p. 5288-98 10 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    40. Published

      Concomitant Inhibition of FASN and SREBP Provides a Promising Therapy for CTCL

      Chi, C., Harth, Lisa, Ramírez Galera, Marina, Torrealba, M. P., Vadivel, Chella Krishna, Geisler, Carsten, Bonefeld, Charlotte Menne, Nielsen, Pia Rude, Bzorek, M., Becker, J. C., Gjerdrum, Lise Mette Rahbek, Ødum, Niels & Woetmann, Anders , 2022, In: Cancers. 14, 18, 4491.

      Research output: Contribution to journal › Journal article › Research › peer-review

    41. Published

      Recruitment of SHP-1 protein tyrosine phosphatase and signalling by a chimeric T-cell receptor-killer inhibitory receptor

      Bartels, Mette Damkjær & Geisler, Carsten, 2000, In: Scandinavian Journal of Immunology. 51, 6, p. 557-64 7 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    42. Published

      Cytokine Profile in Patients with Aseptic Loosening of Total Hip Replacements and Its Relation to Metal Release and Metal Allergy

      Christiansen, R. J., Münch, H. J., Bonefeld, Charlotte Menne, Thyssen, Jacob Pontoppidan, Sloth, J. J., Geisler, Carsten, Søballe, K., Jellesen, M. S. & Jakobsen, S. S., 2019, In: Journal of Clinical Medicine. 8, 8, 15 p., 1259.

      Research output: Contribution to journal › Journal article › Research › peer-review

    43. Published

      T-cell activation. V. Anti-major histocompatibility complex class I antibody-induced activation and clonal abortion in Jurkat T-leukaemic cells

      Claesson, Mogens Helweg, Dissing, Steen, Tscherning, T. & Geisler, Carsten, 1993, In: Immunology. 78, 3, p. 444-8 4 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    44. Published

      Increased prevalence of lymphoid tissue inducer cells in the cerebrospinal fluid of patients with early multiple sclerosis

      Degn, M., Modvig, S., Dyring-Andersen, Beatrice, Bonefeld, Charlotte Menne, Fredriksen, Jette Lautrup, Geisler, Carsten & von Essen, Marina Rode, Jul 2016, In: Multiple Sclerosis Journal. 22, 8, p. 1013-1020 8 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    45. Published

      The phosphorylation state of CD3gamma influences T cell responsiveness and controls T cell receptor cycling

      Dietrich, J., Bäckström, T., Lauritsen, J. P., Kastrup, J., Bartels, Mette Damkjær, von Bülow, F., Palmer, E. & Geisler, Carsten, 1998, In: Journal of Biological Chemistry. 273, 37, p. 24232-8 6 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    46. Published

      TCR¿ is transported to and retained in the Golgi apparatus independently of other TCR chains: implications for TCR assembly

      Dietrich, J., Kastrup, J., Lauritsen, J. P. H., Bonefeld, Charlotte Menne, von Bülow, F. & Geisler, Carsten, 1999, In: European Journal of Immunology. 29, 5, p. 1719-28 9 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    47. Published

      Role of CD3 gamma in T cell receptor assembly

      Dietrich, J., Neisig, A., Hou, X., Wegener, A. M., Gajhede, Michael & Geisler, Carsten, 1996, In: Journal of Cell Biology. 132, 3, p. 299-310 11 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    48. Published

      Molecular characterization of the di-leucine-based internalization motif of the T cell receptor

      Dietrich, J., Hou, X., Wegener, A. M., Pedersen, L. O., Odum, N. & Geisler, Carsten, 1996, In: Journal of Biological Chemistry. 271, 19, p. 11441-8 7 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    49. Published

      T cell receptor zeta allows stable expression of receptors containing the CD3gamma leucine-based receptor-sorting motif

      Dietrich, J. & Geisler, Carsten, 1998, In: Journal of Biological Chemistry. 273, 41, p. 26281-4 3 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    50. Published

      Regulation and function of the CD3¿ DxxxLL motif: a binding site for adaptor protein-1 and adaptor protein-2 in vitro

      Dietrich, J., Kastrup, J., Nielsen, B. L., Odum, N. & Geisler, Carsten, 1997, In: Journal of Cell Biology. 138, 2, p. 271-81 10 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

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