Allergic contact dermatitis induces upregulation of identical microRNAs in humans and mice
Research output: Contribution to journal › Journal article › Research › peer-review
MicroRNAs are short, endogenous RNA molecules that can bind to parts of target mRNAs, thus inhibiting their translation and causing accelerated turnover or degradation of transcripts, thereby regulating gene expression. Several microRNAs have been found to be upregulated in atopic dermatitis and psoriasis, indicating a role in inflammatory skin diseases. However, there have been no studies on the expression of microRNAs in allergic contact dermatitis.
Original language | English |
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Book series | Contact Dermatitis. Supplement |
Volume | 67 |
Issue number | 5 |
Pages (from-to) | 298-305 |
Number of pages | 8 |
ISSN | 1396-6669 |
DOIs | |
Publication status | Published - Nov 2012 |
- Adult, Animals, Cyclopropanes, Dermatitis, Allergic Contact, Disease Models, Animal, Female, Humans, Mice, Mice, Inbred C57BL, MicroRNAs, Microarray Analysis, Middle Aged, Skin, Up-Regulation
Research areas
ID: 46484815