Allergic contact dermatitis induces upregulation of identical microRNAs in humans and mice

Research output: Contribution to journalJournal articleResearchpeer-review

MicroRNAs are short, endogenous RNA molecules that can bind to parts of target mRNAs, thus inhibiting their translation and causing accelerated turnover or degradation of transcripts, thereby regulating gene expression. Several microRNAs have been found to be upregulated in atopic dermatitis and psoriasis, indicating a role in inflammatory skin diseases. However, there have been no studies on the expression of microRNAs in allergic contact dermatitis.
Original languageEnglish
Book seriesContact Dermatitis. Supplement
Volume67
Issue number5
Pages (from-to)298-305
Number of pages8
ISSN1396-6669
DOIs
Publication statusPublished - Nov 2012

    Research areas

  • Adult, Animals, Cyclopropanes, Dermatitis, Allergic Contact, Disease Models, Animal, Female, Humans, Mice, Mice, Inbred C57BL, MicroRNAs, Microarray Analysis, Middle Aged, Skin, Up-Regulation

ID: 46484815