Allergic contact dermatitis induces upregulation of identical microRNAs in humans and mice
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Allergic contact dermatitis induces upregulation of identical microRNAs in humans and mice. / Vennegaard, Marie T; Bonefeld, Charlotte M; Hagedorn, Peter; Bangsgaard, Nannie; Løvendorf, Marianne B; Odum, Niels; Woetmann, Anders; Geisler, Carsten; Skov, Lone.
In: Contact Dermatitis. Supplement, Vol. 67, No. 5, 11.2012, p. 298-305.Research output: Contribution to journal › Journal article › Research › peer-review
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TY - JOUR
T1 - Allergic contact dermatitis induces upregulation of identical microRNAs in humans and mice
AU - Vennegaard, Marie T
AU - Bonefeld, Charlotte M
AU - Hagedorn, Peter
AU - Bangsgaard, Nannie
AU - Løvendorf, Marianne B
AU - Odum, Niels
AU - Woetmann, Anders
AU - Geisler, Carsten
AU - Skov, Lone
N1 - © 2012 John Wiley & Sons A/S.
PY - 2012/11
Y1 - 2012/11
N2 - MicroRNAs are short, endogenous RNA molecules that can bind to parts of target mRNAs, thus inhibiting their translation and causing accelerated turnover or degradation of transcripts, thereby regulating gene expression. Several microRNAs have been found to be upregulated in atopic dermatitis and psoriasis, indicating a role in inflammatory skin diseases. However, there have been no studies on the expression of microRNAs in allergic contact dermatitis.
AB - MicroRNAs are short, endogenous RNA molecules that can bind to parts of target mRNAs, thus inhibiting their translation and causing accelerated turnover or degradation of transcripts, thereby regulating gene expression. Several microRNAs have been found to be upregulated in atopic dermatitis and psoriasis, indicating a role in inflammatory skin diseases. However, there have been no studies on the expression of microRNAs in allergic contact dermatitis.
KW - Adult
KW - Animals
KW - Cyclopropanes
KW - Dermatitis, Allergic Contact
KW - Disease Models, Animal
KW - Female
KW - Humans
KW - Mice
KW - Mice, Inbred C57BL
KW - MicroRNAs
KW - Microarray Analysis
KW - Middle Aged
KW - Skin
KW - Up-Regulation
U2 - 10.1111/j.1600-0536.2012.02083.x
DO - 10.1111/j.1600-0536.2012.02083.x
M3 - Journal article
C2 - 22594804
VL - 67
SP - 298
EP - 305
JO - Contact Dermatitis. Supplement
JF - Contact Dermatitis. Supplement
SN - 1396-6669
IS - 5
ER -
ID: 46484815