Niels Ødum

Niels Ødum

Professor

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    ORCID: 0000-0003-3135-5624

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    1. Published

      Investigating potential exogenous tumor initiating and promoting factors for Cutaneous T-Cell Lymphomas (CTCL), a rare skin malignancy

      Litvinov, I. V., Shtreis, A., Kobayashi, K., Glassman, S., Tsang, M., Woetmann, Anders , Sasseville, D., Ødum, Niels & Duvic, M., 2 Jul 2016, In: OncoImmunology. 5, 7, 5 p., e1175799.

      Research output: Contribution to journal › Review › Research › peer-review

    2. Published

      Vitamin D Inhibits IL-22 Production Through a Repressive Vitamin D Response Element in the il22 Promoter

      Lopez, D. V., Al-Jaberi, F. A. H., Damas, N. D., Weinert, B. T., Pus, U., Torres-Rusillo, S., Woetmann, Anders , Ødum, Niels, Bonefeld, Charlotte Menne, Kongsbak-Wismann, Martin & Geisler, Carsten, 2021, In: Frontiers in Immunology. 12, 715059.

      Research output: Contribution to journal › Journal article › Research › peer-review

    3. Published

      Macrophages Control the Bioavailability of Vitamin D and Vitamin D-Regulated T Cell Responses

      Lopez, D. V., Al-Jaberi, F. A. H., Woetmann, Anders , Ødum, Niels, Bonefeld, Charlotte Menne, Kongsbak-Wismann, Martin & Geisler, Carsten, 2021, In: Frontiers in Immunology. 12, 722806.

      Research output: Contribution to journal › Journal article › Research › peer-review

    4. Published

      Constitutive STAT3 activation in intestinal T cells from patients with Crohn's disease

      Lovato, P., Brender, C., Agnholt, J., Kelsen, J., Kaltoft, K., Svejgaard, A., Eriksen, K. W., Woetmann, Anders & Ødum, Niels, 2003, In: Journal of Biological Chemistry. 278, 19, p. 16777-81 4 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    5. Published

      SHP2 regulates IL-2 induced MAPK activation, but not Stat3 or Stat5 tyrosine phosphorylation, in cutaneous T cell lymphoma cells

      Lundin Brockdorff, J., Woetmann, Anders , Mustelin, T., Kaltoft, K., Zhang, Q., Wasik, M. A., Röpke, C. & Ødum, Niels, 2002, In: Cytokine. 20, 4, p. 141-7 6 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    6. Published

      IL-15 induces unspecific effector functions in human peptide-specific CD8+ T-cell cultures.

      Lyngstrand, S. T., Würtzen, P. A., Ødum, Niels, Nissen, Mogens Holst & Röpke, C., 2002, In: Scandinavian Journal of Immunology. 56, 6, p. 602-10 8 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    7. Published

      Comparison of microRNA expression using different preservation methods of matched psoriatic skin samples

      Løvendorf, M. B., Zibert, J. R., Hagedorn, P. H., Glue, C., Ødum, Niels, Røpke, M. A. & Skov, L., 2012, In: Experimental Dermatology. 21, 4, p. 299-301 3 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    8. Published

      New DPB1 alleles

      Madsen, H. O., Ryder, L. P., Fugger, L., Ødum, Niels, Jakobsen, B. K. & Svejgaard, A., 1992, In: HLA. 39, 2, p. 102-3 1 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    9. Published

      Imbalanced IL-1B and IL-18 Expression in Sézary Syndrome

      Manfrere, K. C. G., Torrealba, M. P., Ferreira, F. M., de Sousa, E. S. A., Miyashiro, D., Teixeira, F. M. E., Custódio, R. W. A., Nakaya, H. I., Ramos, Y. A. L., Sotto, M. N., Woetmann, Anders , Ødum, Niels, Duarte, A. J. D. S., Sanches, J. A. & Sato, M. N., 2023, In: International Journal of Molecular Sciences. 24, 5, 4674.

      Research output: Contribution to journal › Journal article › Research › peer-review

    10. Published

      miR-122 regulates p53/Akt signalling and the chemotherapy-induced apoptosis in cutaneous T-cell lymphoma

      Manfè, V., Biskup, E., Rosbjerg, A., Kamstrup, M., Skov, A. G., Lerche, C. M., Lauenborg, B. T., Ødum, Niels & Gniadecki, R., Jan 2012, In: PLOS ONE. 7, 1, e29541.

      Research output: Contribution to journal › Journal article › Research › peer-review

    11. Published

      cMyc/miR-125b-5p signalling determines sensitivity to bortezomib in preclinical model of cutaneous T-cell lymphomas

      Manfè, V., Biskup, E., Willumsgaard, A., Skov, A. G., Palmieri, D., Gasparini, P., Laganá, A., Woetmann, Anders , Ødum, Niels, Croce, C. M. & Gniadecki, R., 2013, In: PloS one. 8, 3, p. e59390

      Research output: Contribution to journal › Journal article › Research › peer-review

    12. Published

      Validation of a diagnostic miRNA classifier in cutaneous T-cell lymphomas

      Marstrand, T., Ahler, C. B., Ralfkiaer, U., Clemmensen, A., Kopp, K. L., Sibbesen, N. A., Krejsgaard, T., Litman, Thomas, Wasik, M. A., Bonefeld, Charlotte Menne, Grønbæk, Kirsten, Gjerdum, L. M. R., Gniadecki, R., Ralfkiaer, E., Geisler, Carsten, Woetmann, Anders , Røpke, M. A., Glue, C., Skov, Lone & Ødum, Niels, 2014, In: Leukemia and Lymphoma. 55, 4, p. 957-958 2 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    13. Published

      Citrullination of myelin basic protein induces a Th17-cell response in healthy individuals and enhances the presentation of MBP85-99 in patients with multiple sclerosis

      Martín Monreal, M. T., Hansen, B. E., Iversen, P. F., Enevold, Christian, Ødum, Niels, Sellebjerg, Finn Thorup, Højrup, P., von Essen, Marina Rode & Nielsen, Claus Henrik, 2023, In: Journal of Autoimmunity. 139, 103092.

      Research output: Contribution to journal › Journal article › Research › peer-review

    14. Published

      Applicability of Small-Molecule Inhibitors in the Study of Peptidyl Arginine Deiminase 2 (PAD2) and PAD4

      Martín Monreal, M. T., Stripp, Alexandra, Massarenti, Laura, Mondal, S., Šenolt, L., Ødum, Niels, Nielsen, Michael Lund, Thompson, P. R., Nielsen, Claus Henrik & Damgaard, D., 2021, In: Frontiers in Immunology. 12, 11 p., 716250.

      Research output: Contribution to journal › Journal article › Research › peer-review

    15. Published

      Differential Effects of Interleukin-2 and Interleukin-15 versus Interleukin-21 on CD4+ Cutaneous T-Cell Lymphoma Cells

      Marzec, Michal Tomasz, Halasa, K., Kasprzycka, M., Wysocka, M., Liu, X., Tobias, J. W., Baldwin, D., Zhang, Q., Ødum, Niels, Rook, A. H. & Wasik, M. A., 2008, In: Cancer Research. 68, 4, p. 1083-91 8 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    16. Published

      Malignant transformation of CD4+ T lymphocytes mediated by oncogenic kinase NPM/ALK recapitulates IL-2-induced cell signaling and gene expression reprogramming

      Marzec, Michal Tomasz, Halasa, K., Liu, X., Wang, H. Y., Cheng, M., Baldwin, D., Tobias, J. W., Schuster, S. J., Woetmann, Anders , Zhang, Q., Turner, S. D., Ødum, Niels & Wasik, M. A., 15 Dec 2013, In: Journal of immunology (Baltimore, Md. : 1950). 191, 12, p. 6200-7 8 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    17. Published

      IL-2- and IL-15-induced activation of the rapamycin-sensitive mTORC1 pathway in malignant CD4+ T lymphocytes

      Marzec, Michal Tomasz, Liu, X., Kasprzycka, M., Witkiewicz, A., Raghunath, P. N., El-Salem, M., Robertson, E., Ødum, Niels & Wasik, M. A., 2008, In: Blood. 111, 4, p. 2181-9 8 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    18. Published

      Inhibition of ALK enzymatic activity in T-cell lymphoma cells induces apoptosis and suppresses proliferation and STAT3 phosphorylation independently of Jak3

      Marzec, Michal Tomasz, Kasprzycka, M., Ptasznik, A., Wlodarski, P., Zhang, Q., Ødum, Niels & Wasik, M. A., 2005, In: Laboratory Investigation. 85, 12, p. 1544-54 10 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    19. Published

      Oncogenic kinase NPM/ALK induces expression of HIF1 alpha mRNA

      Marzec, Michal Tomasz, Liu, X., Wong, W., Yang, Y., Pasha, T., Kantekure, K., Zhang, P., Woetmann, Anders , Cheng, M., Ødum, Niels & Wasik, M. A., 2011, In: Oncogene. 30, 11, p. 1372-1378 7 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    20. Published

      Simultaneous inhibition of mTOR-containing complex 1 (mTORC1) and MNK induces apoptosis of cutaneous T-cell lymphoma (CTCL) cells

      Marzec, Michal Tomasz, Liu, X., Wysocka, M., Rook, A. H., Ødum, Niels & Wasik, M. A., 16 Sep 2011, In: PLoS ONE. 6, 9, 8 p., e24849.

      Research output: Contribution to journal › Journal article › Research › peer-review

    21. Published

      Inhibition of allostimulated HLA-DQ and DP-specific T cells by staphylococcal enterotoxin A

      Masewicz, S., Ledbetter, J. A., Martin, P., Mickelson, E., Hansen, J. A. & Ødum, Niels, 1993, In: Human Immunology. 36, 3, p. 142-8 6 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    22. Published

      Peptidylarginine deiminase-4 gene polymorphisms are associated with systemic lupus erythematosus and lupus nephritis

      Massarenti, Laura, Enevold, C., Damgaard, D., Ødum, Niels, Nielsen, Claus Henrik & Jacobsen, Søren, 2019, In: Scandinavian Journal of Rheumatology. 48, 2, p. 133-140

      Research output: Contribution to journal › Journal article › Research › peer-review

    23. Published

      Peptidylarginine Deiminase 2 Gene Polymorphisms in Subjects with Periodontitis Predispose to Rheumatoid Arthritis

      Massarenti, Laura, Enevold, C., Damgaard, D., Hansen, Peter Riis, Frisch, M., Ødum, Niels, Jacobsen, Søren & Nielsen, Claus Henrik, 2022, In: International Journal of Molecular Sciences. 23, 17, 10 p., 9536.

      Research output: Contribution to journal › Journal article › Research › peer-review

    24. Published

      PADI4 Polymorphisms Confer Risk of Anti-CCP-Positive Rheumatoid Arthritis in Synergy With HLA-DRB1*04 and Smoking

      Massarenti, Laura, Enevold, C., Damgaard, D., Ødum, Niels, Garred, Peter, Frisch, M., Shelef, M. A., Jacobsen, Søren & Nielsen, Claus Henrik, 2021, In: Frontiers in Immunology. 12, 707690.

      Research output: Contribution to journal › Journal article › Research › peer-review

    25. Published

      Bacterial genotoxins induce T cell senescence

      Mathiasen, S. L., Gall Mas, Laura, Pateras, I. S., Theodorou, S. D. P., Namini, Martin Rich Javadi, Hansen, Morten Bagge, Martin, O. C. B., Vadivel, Chella Krishna, Ntostoglou, K., Butter, D., Givskov, Michael, Geisler, Carsten, Akbar, A. N., Gorgoulis, V. G., Frisan, T., Ødum, Niels & Krejsgaard, T., 2021, In: Cell Reports. 35, 10, 109220.

      Research output: Contribution to journal › Journal article › Research › peer-review

    26. Published

      Ceramide-induced TCR up-regulation

      Bonefeld, Charlotte Menne, Lauritsen, J. P. H., Dietrich, J., Kastrup, J., Wegener, A. M., Ødum, Niels & Geisler, Carsten, 2000, In: Journal of Immunology. 165, 6, p. 3065-72 7 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    27. Published

      Endo- and exocytic rate constants for spontaneous and protein kinase C-activated T cell receptor cycling

      Bonefeld, Charlotte Menne, Møller Sørensen, T., Siersma, Volkert Dirk, von Essen, Marina Rode, Ødum, Niels & Geisler, Carsten, 2002, In: European Journal of Immunology. 32, 3, p. 616-26 10 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    28. Published

      Androgen dependent mechanisms of pro-angiogenic networks in placental and tumor development

      Metzler, V. M., de Brot, S., Robinson, R. S., Jeyapalan, J. N., Rakha, E., Walton, T., Gardner, D. S., Lund, E. F., Whitchurch, J., Haigh, D., Lochray, J. M., Robinson, B. D., Allegrucci, C., Fray, R. G., Persson, J. L., Ødum, N., Miftakhova, R. R., Rizvanov, A. A., Hughes, I. A., Tadokoro-Cuccaro, R. & 3 others, Heery, D. M., Rutland, C. S. & Mongan, N. P., 2017, In: Placenta. 56, p. 79-85

      Research output: Contribution to journal › Journal article › Research › peer-review

    29. Published

      Low prevalence of antibodies and other plasma factors binding to CC chemokines and IL-2 in HIV-positive patients

      Meyer, C. N., Svenson, M., Schade Larsen, C., Ødum, Niels, Skinhøj, P. & Bendtzen, K., 2000, In: Acta Pathologica Microbiologica et Immunologica Scandinavica. 108, 2, p. 122-30 9 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    30. Published

      Low prevalence of antibodies and other factors binding to CC-chemokines and IL-2 in HIV-positive patients

      Meyer, C. N., Svenson, M., Larsen, C. S., Ødum, Niels, Skinhøj, P. & Bendzen, K., 2000, In: APMIS : Acta pathologica, microbiologica et immunologica Scandinavica. Supplementum. 108, p. 122-130

      Research output: Contribution to journal › Journal article › Research › peer-review

    31. Published

      Proinflammatory biomarkers are associated with prediabetes in patients with schizophrenia

      Mller, M., Fredholm, S., Jensen, M. E., Wörtwein, Gitta, Larsen, J. R., Vilsbøll, Tina, Ødum, Niels & Fink-Jensen, Anders, 2022, In: CNS Spectrums. 27, 3, 8 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    32. Published

      Characterization of circulating extracellular traps and immune responses to citrullinated LL37 in psoriasis

      Monreal, M. T. M., Kvist-Hansen, A., Massarenti, Laura, Steffensen, R., Loft, N., Hansen, Peter Riis, Ødum, Niels, Skov, Lone & Nielsen, Claus Henrik, 2023, In: Frontiers in Immunology. 14, 10 p., 1247592.

      Research output: Contribution to journal › Journal article › Research › peer-review

    33. Published

      DNA polymorphism of HLA class II genes in alopecia areata

      Morling, Niels, Frentz, G., Fugger, L., Georgsen, J., Jakobsen, B., Ødum, Niels & Svejgaard, A., 1992, In: Disease Markers. 9, 1, p. 35-42 7 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    34. Published

      DNA polymorphism of HLA class II genes in pauciarticular juvenile rheumatoid arthritis

      Morling, Niels, Friis, J., Fugger, L., Georgsen, J., Heilmann, C., Pedersen, F. K., Ødum, Niels & Svejgaard, A., 1991, In: HLA. 38, 1, p. 16-23 7 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    35. Published

      Immunogenetics of rheumatoid arthritis and primary Sjögren's syndrome: DNA polymorphism of HLA class II genes

      Morling, Niels, Andersen, V., Fugger, L., Georgsen, J., Halberg, P., Oxholm, P., Ødum, Niels & Svejgaard, A., 1992, In: Disease Markers. 9, 5, p. 289-296 7 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    36. Published

      DNA polymorphism of HLA class II genes in primary biliary cirrhosis

      Morling, Niels, Dalhoff, K., Fugger, L., Georgsen, J., Jakobsen, B., Ranek, L., Ødum, Niels & Svejgaard, A., 1992, In: Immunogenetics. 35, 2, p. 112-6 4 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    37. Published

      The junctional adhesion molecule-like protein (JAML) is important for the inflammatory response during contact hypersensitivity

      Mraz, Veronika, Lohmann, R. K. D., Menzel, Mandy, Hawkes, A., Vaher, Helen, Funch, Anders Boutrup, Jee, Mia Hamilton, Gadsbøll, A. S. Ø., Weber, Julie Friis, Yeung, Kelvin, Ødum, Niels, Woetmann, Anders , McKay, D., Witherden, D., Geisler, Carsten & Bonefeld, Charlotte Menne, 2023, In: Contact Dermatitis. 89, 5, p. e63-e65

      Research output: Contribution to journal › Journal article › Research › peer-review

    38. Published

      CD100 boosts the inflammatory response in the challenge phase of allergic contact dermatitis in mice

      Mraz, Veronika, Funch, Anders Boutrup, Jee, Mia Hamilton, Gadsbøll, A. S. Ø., Weber, Julie Friis, Yeung, Kelvin, Lohmann, R. K. D., Hawkes, A., Ødum, Niels, Woetmann, Anders , McKay, D., Witherden, D., Geisler, Carsten & Bonefeld, Charlotte Menne, 2023, In: Contact Dermatitis. 89, 6, p. 442-452

      Research output: Contribution to journal › Journal article › Research › peer-review

    39. Published

      HLA-DP antigens in patients with chronic autoimmune thrombocytopenia (AITP)

      Mueller-Eckhardt, G., Pawelec, G., Haas, R., Otto, C., Kiefel, V., Ødum, Niels & Mueller-Eckhardt, C., 1989, In: HLA. 34, 2, p. 121-6 5 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    40. Published

      Cutaneous T cell lymphoma cells are targets for immune checkpoint ligand PD-L1-specific, cytotoxic T cells

      Munir, S., Andersen, G. H., Woetmann, Anders , Ødum, Niels, Becker, J. C. & Andersen, Mads Hald, Nov 2013, In: Leukemia. 27, 11, p. 2251-3 3 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    41. Published

      Immunodeficiency after allogeneic bone marrow transplantation in man. Effect of phorbol ester (phorbol myristate acetate) and calcium ionophore (A23187) in vitro

      Møller, J., Hofmann, B., Langhoff, E., Damgård Jacobsen, K., Ødum, Niels, Dickmeiss, E., Ryder, L. P., Thastrup, O., Scharff, O. & Foder, B., 1989, In: Scandinavian Journal of Immunology. 30, 4, p. 441-7 6 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    42. Published

      1,25-dihydroxyvitamin D3 selectively reduces interleukin-2 levels and proliferation of human T cell lines in vitro

      Müller, K., Ødum, Niels & Bendtzen, K., 1993, In: Immunology Letters. 35, 2, p. 177-82 5 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    43. Published

      Multi-gene epigenetic silencing of tumor suppressor genes in T-cell lymphoma cells; delayed expression of the p16 protein upon reversal of the silencing

      Nagasawa, T., Zhang, Q., Raghunath, P. N., Wong, H. Y., El-Salem, M., Szallasi, A., Marzec, Michal Tomasz, Gimotty, P., Rook, A. H., Vonderheid, E. C., Ødum, Niels & Wasik, M. A., 2006, In: Leukemia research : a Forum for Studies on Leukemia and Normal Hemopoiesis. 30, 3, p. 303-12 9 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    44. Published

      Inhibition of succinate dehydrogenase activity impairs human T cell activation and function: [Publisher correction]

      Nastasi, C., Willerlev-Olsen, A., Dalhoff, K., Ford, Shayne Lavondua, Gadsbøll, A. S. Ø., Buus, Terkild Brink, Gluud, Maria, Danielsen, M., Litman, Thomas, Bonefeld, Charlotte Menne, Geisler, Carsten, Ødum, Niels & Woetmann, Anders , 2021, In: Scientific Reports. 11, 1, 1458.

      Research output: Contribution to journal › Journal article › Research › peer-review

    45. Published

      The effect of short-chain fatty acids on human monocyte-derived dendritic cells

      Nastasi, C., Candela, M., Bonefeld, Charlotte Menne, Geisler, Carsten, Hansen, M., Krejsgaard, T., Biagi, E., Andersen, Mads Hald, Brigidi, P., Ødum, Niels, Litman, T. & Woetmann, Anders , 2015, In: Scientific Reports. 5, 10 p., 16148.

      Research output: Contribution to journal › Journal article › Research › peer-review

    46. Published

      Butyrate and propionate inhibit antigen-specific CD8+ T cell activation by suppressing IL-12 production by antigen-presenting cells

      Nastasi, C., Fredholm, S., Willerslev-Olsen, A., Hansen, M., Bonefeld, Charlotte Menne, Geisler, Carsten, Andersen, Mads Hald, Ødum, Niels & Woetmann, Anders , Dec 2017, In: Scientific Reports. 7, 10 p., 14516.

      Research output: Contribution to journal › Journal article › Research › peer-review

    47. Published

      Analysis of CTCL cell lines reveals important differences between mycosis fungoides/Sézary syndrome vs. HTLV-1+ leukemic cell lines

      Netchiporouk, E., Gantchev, J., Tsang, M., Thibault, P., Watters, A. K., Hughes, J. D. M., Ghazawi, F. M., Woetmann, Anders , Ødum, Niels, Sasseville, D. & Litvinov, I. V., 2017, In: OncoTarget. 8, 56, p. 95981-95998 18 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    48. Published

      MHC class II molecules regulate growth in human T cells

      Nielsen, M., Ødum, Niels, Bendtzen, K., Ryder, L. P., Jakobsen, B. K. & Svejgaard, A., 1994, In: Experimental and Clinical Immunogenetics. 11, 1, p. 23-32 9 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    49. Published

      Interleukin-2 induces tyrosine phosphorylation and nuclear translocation of stat3 in human T lymphocytes

      Nielsen, M., Svejgaard, A., Skov, S. & Ødum, Niels, 1994, In: European Journal of Immunology. 24, 12, p. 3082-6 4 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    50. Published

      Staphylococcal enterotoxins modulate interleukin 2 receptor expression and ligand-induced tyrosine phosphorylation of the Janus protein-tyrosine kinase 3 (Jak3) and signal transducers and activators of transcription (Stat proteins)

      Nielsen, M., Svejgaard, A., Röpke, C., Nordahl, M. & Ødum, Niels, 1995, In: Proceedings of the National Academy of Science of the United States of America. 92, 24, p. 10995-9 4 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

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