Niels Ødum
Professor
Skin Immunology Research Center
Blegdamsvej 3B, 2200 København N, 07 Bygning 7, Building: 07-12-86
Member of:
- 2012
- Published
miR-122 regulates p53/Akt signalling and the chemotherapy-induced apoptosis in cutaneous T-cell lymphoma
Manfè, V., Biskup, E., Rosbjerg, A., Kamstrup, M., Skov, A. G., Lerche, C. M., Lauenborg, B. T., Ødum, Niels & Gniadecki, R., Jan 2012, In: PLOS ONE. 7, 1, e29541.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Comparison of microRNA expression using different preservation methods of matched psoriatic skin samples
Løvendorf, M. B., Zibert, J. R., Hagedorn, P. H., Glue, C., Ødum, Niels, Røpke, M. A. & Skov, L., 2012, In: Experimental Dermatology. 21, 4, p. 299-301 3 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Cytotoxicity of CD56bright NK cells towards autologous activated CD4+ T cells is mediated through NKG2D, LFA-1 and TRAIL and dampened via CD94/NKG2A
Nielsen, N., Ødum, Niels, Ursø, B., Lanier, L. L. & Spee, P., 2012, In: PLoS ONE. 7, 2, 10 p., e31959.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Expression patterns of the immunosuppressive proteins PD-1/CD279 and PD-L1/CD274 at different stages of cutaneous T-Cell lymphoma/mycosis fungoides
Kantekure, K., Yang, Y., Raghunath, P., Schaffer, A., Woetmann, Anders , Zhang, Q., Ødum, Niels & Wasik, M., 2012, In: American Journal of Dermatopathology. 34, 1, p. 126-128 3 p.Research output: Contribution to journal › Letter › Research › peer-review
- Published
Regulatory T cells and immunodeficiency in mycosis fungoides and Sézary syndrome
Krejsgaard, T. F., Ødum, Niels, Geisler, Carsten, Wasik, M. A. & Woetmann, Anders , 2012, In: Leukemia. 26, p. 424-432 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Vascular endothelial growth factor receptor-3 expression in mycosis fungoides
Pedersen, I. H., Willerslev-Olsen, A., Vetter-Kauczok, C., Krejsgaard, T., Lauenborg, B., Kopp, K. L., Geisler, Carsten, Bonefeld, Charlotte Menne, Zhang, Q., Wasik, M. A., Dabelsteen, Sally, Woetmann, Anders , Becker, J. C. & Ødum, Niels, 2012, In: Leukemia and Lymphoma.Research output: Contribution to journal › Journal article › Research › peer-review
- 2011
- Published
The role of cytokine signaling in the pathogenesis of cutaneous T-cell lymphoma
abraham, R., Zhang, Q., Ødum, Niels & Wasis, M., 15 Dec 2011, In: Cancer Biology & Therapy. 12, 12, p. 1019-1022 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Simultaneous inhibition of mTOR-containing complex 1 (mTORC1) and MNK induces apoptosis of cutaneous T-cell lymphoma (CTCL) cells
Marzec, Michal Tomasz, Liu, X., Wysocka, M., Rook, A. H., Ødum, Niels & Wasik, M. A., 16 Sep 2011, In: PLoS ONE. 6, 9, 8 p., e24849.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Oncogenic tyrosine kinase NPM-ALK induces expression of the growth-promoting receptor ICOS
Zhang, Q., Wang, H., Kantekure, K., Paterson, J. C., Liu, X., Schaffer, A., Paulos, C., Milone, M. C., Ødum, Niels, Turner, S., Marafioti, T. & Wasik, M. A., 15 Sep 2011, In: Blood. 118, 11, p. 3062-3071 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
IFN-α primes T- and NK-cells for IL-15-mediated signaling and cytotoxicity
Hansen, M. L., Woetmann, Anders , Krejsgaard, T., Kopp, K. L. M., Søkilde, R., Litman, Thomas, Straten, P. T., Geisler, Carsten, Wasik, M. A., Ødum, Niels & Eriksen, K. W., Sep 2011, In: Molecular Immunology. 48, 15-16, p. 2087-93 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Diagnostic microRNA profiling in cutaneous T-cell lymphoma (CTCL)
Ralfkiaer, U., Hagedorn, P., Bangsgaard, N., Løvendorf, M. B., Ahler, C. B., Svensson, L., Kopp, K. L., Vennegaard, M. T., Lauenborg, B., Zibert, J. R., Krejsgaard, T., Bonefeld, C. M., Søkilde, R., Gjerdrum, L. M., Labuda, T., Mathiesen, A-M., Grønbaek, K., Wasik, M. A., Sokolowska-Wojdylo, M., Queille-Roussel, C. & 9 others, , 2011, In: Blood. 118, 22, p. 5891-5900 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
JNK1, but not JNK2, is required in two mechanistically distinct models of inflammatory arthritis
Denninger, K., Rasmussen, S. B., Larsen, J. M., Ørskov, Cathrine, Poulsen, Steen Seier, Sørensen, P., Christensen, Jan Pravsgaard, Illges, H., Ødum, Niels & Labuda, T., 2011, In: American Journal of Pathology. 179, 4, p. 1884-93 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Malignant cutaneous T-cell lymphoma cells express IL-17 utilizing the Jak3/Stat3 signaling pathway
Krejsgaard, T. F., Ralfkiær, U., Clasen-Linde, E., Eriksen, K. W. K., Kopp, K. L. M., Bonefeld, Charlotte Menne, Geisler, Carsten, Dabelsteen, Sally, Wasik, M. A., Ralfkiaer, E. M., Woetmann, Anders & Ødum, Niels, 2011, In: Journal of Investigative Dermatology. 131, 6, p. 1331-1338 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Oncogenic kinase NPM/ALK induces expression of HIF1 alpha mRNA
Marzec, Michal Tomasz, Liu, X., Wong, W., Yang, Y., Pasha, T., Kantekure, K., Zhang, P., Woetmann, Anders , Cheng, M., Ødum, Niels & Wasik, M. A., 2011, In: Oncogene. 30, 11, p. 1372-1378 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Response to Shawn G. Kwatra.
Krejsgaard, T. F., Woetmann, Anders & Ødum, Niels, 2011, In: Journal of Investigative Dermatology. 131, 9, p. 1955–1956 2 p.Research output: Contribution to journal › Comment/debate › Research › peer-review
- Published
TCR down-regulation boosts T-cell-mediated cytotoxicity and protection against poxvirus infections
Hansen, A. K., Regner, M., Bonefeld, Charlotte Menne, Boding, L., Kongsbak-Wismann, Martin, Ødum, Niels, Müllbacher, A., Geisler, Carsten & von Essen, Marina Rode, 2011, In: European Journal of Immunology. 41, 7, p. 1948-1957 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2010
- Published
COX-2 is a novel target in therapy of mycosis fungoides
Kopp, K. L. M., Dabelsteen, Sally, Krejsgaard, T., Eriksen, K. W., Geisler, Carsten, Becker, J. C., Wasik, M., Ødum, Niels & Danielsen, A. L. W., 1 Dec 2010, In: Leukemia. 24, 12, p. 2127-9 3 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Expression of full-length and splice forms of FoxP3 in rheumatoid arthritis
Ryder, L. R., Woetmann, Anders , Madsen, H. O., Ødum, Niels, Ryder, L. P., Bliddal, H., Danneskiold-Samsøe, B., Ribel-Madsen, S., Bartels, E. M., Ryder, L. R., Danielsen, A. L. W., Madsen, H. O., Ødum, N., Ryder, L. P., Bliddal, Henning, Danneskiold-Samsøe, B., Ribel-Madsen, S. & Bartels, E. M., 1 Aug 2010, In: Scandinavian Journal of Rheumatology. 39, 4, p. 279-86 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Notch 1 as a potential therapeutic target in cutaneous T-cell lymphoma
Kamstrup, M. R., Gjerdrum, Lise Mette Rahbek, Biskup, E. U., Lauenborg, B. T., Ralfkiær, E. M., Woetmann, Anders , Ødum, Niels & Gniadecki, R., 7 Jan 2010, In: Blood. 116, 14, p. 2504-12Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A novel xenograft model of cutaneous T-cell lymphoma
Krejsgaard, T., Kopp, K., Ralfkiaer, E., Willumsgaard, A. E., Eriksen, K. W., Labuda, T., Rasmussen, S., Mathiesen, A., Geisler, Carsten, Lauenborg, B., Becker, J. C., Zhang, Q., Wasik, M. A., Ødum, Niels & Woetmann, Anders , 2010, In: Experimental Dermatology. 19, 12, p. 1096-102 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
COX-2-dependent PGE2 acts as a growth factor in mycosis fungoides (MF)
Kopp, K. L. M., Kauczok, C. S., Lauenborg, B. T., Krejsgaard, T. F., Eriksen, K. W. K., Zhang, Q., Wasik, M. A., Geisler, Carsten, Ralfkiaer, E. M., Becker, J. C., Ødum, Niels & Woetmann, Anders , 2010, In: Leukemia. 24, 6, p. 1179-1185 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Deficient SOCS3 and SHP-1 Expression in Psoriatic T Cells
Eriksen, K. W., Woetmann, Anders , Skov, Lone, Krejsgaard, T., Bovin, L. F., Hansen, M. L., Grønbæk, Kirsten, Billestrup, Nils, Nissen, Mogens Holst, Geisler, Carsten, Wasik, M. A. & Ødum, Niels, 2010, In: Journal of Investigative Dermatology. 130, 6, p. 1590-7 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Intratumoral interleukin-21 increases antitumor immunity, tumor-infiltrating CD8+ T-cell density and activity, and enlarges draining lymph nodes
Søndergaard, H., Galsgaard, E. D., Bartholomaeussen, M., Straten, P. T., Ødum, Niels & Skak, K., 2010, In: Journal of Immunotherapy. 33, 3, p. 236-49 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Malignant T cells exhibit CD45 resistant Stat 3 activation and proliferation in cutaneous T cell lymphoma.
Krejsgaard, T., Helvad, R., Ralfkiær, E., Astvad, K., Grønbæk, K., Eriksen, K., Geisler, C., Kopp, K. L. M., Zhang, Q., Ødum, Niels, Woetmann, Anders , Katharina, K., Wasik, M., Odum, N. & Woetmann, A., 2010, In: The Open Leukemia Journal. 3, p. 9-15Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Malignant T cells exhibit CD45 resistant Stat3 activation and proliferation in cutaneous
Krejsgaard, T. F., Helvad, R., Ralfkiaer, E., Astvad, K., Grønbæk, K., Eriksen, K. W., Geisler, C., Kopp, K. L. M., Zhang, Q., Ødum, Niels & Woetmann, Anders , 2010, In: The Open Leukemia Journal. 3, p. 9-15Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Polymorphisms of the T cell receptor CD3delta and CD3varepsilon chains affect anti-CD3 antibody binding and T cell activation
Boding, L., Nielsen, M. W., Bonefeld, Charlotte Menne, von Essen, Marina Rode, Nielsen, B. L., Lauritsen, J. P. H., Hansen, A. K., Nielsen, M. M., Kongsbak, M., Rubin, M., Vennegaard, M. T., Ødum, Niels & Geisler, Carsten, 2010, In: Molecular Immunology. 47, 15, p. 2450-7 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Vitamin D controls T cell antigen receptor signaling and activation of human T cells
von Essen, Marina Rode, Kongsbak-Wismann, Martin, Schjerling, Peter, Ølgaard, Klaus, Ødum, Niels & Geisler, Carsten, 2010, In: Nature Immunology. 11, 4, p. 344-349 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2009
- Published
TCR down-regulation controls virus-specific CD8+ T cell responses
Bonefeld, Charlotte Menne, Haks, M., Nielsen, B., von Essen, Marina Rode, Boding, L., Hansen, A. K., Larsen, J. M., Ødum, Niels, Krimpenfort, P., Kruisbeek, A., Christensen, Jan Pravsgaard, Thomsen, Allan Randrup & Geisler, Carsten, 1 Dec 2009, In: Journal of Immunology. 181, 11, p. 7786-7799 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Ectopic expression of B-lymphoid kinase in cutaneous T-cell lymphoma
Krejsgaard, T., Vetter-Kauczok, C. S., Woetmann, Anders , Kneitz, H., Eriksen, K. W., Lovato, P., Zhang, Q., Wasik, M. A., Geisler, Carsten, Ralfkiaer, E., Becker, J. C. & Ødum, Niels, 2009, In: Blood. 113, 23, p. 5896-904 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
TCR down-regulation controls T cell homeostasis
Boding, L., Bonefeld, Charlotte Menne, Nielsen, B. L., Lauritsen, J. P. H., von Essen, Marina Rode, Hansen, A. K., Larsen, J. M., Nielsen, M. M., Ødum, Niels & Geisler, Carsten, 2009, In: Journal of Immunology. 183, 8, p. 4994-5005 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2008
- Published
gamma c-signaling cytokines induce a regulatory T cell phenotype in malignant CD4(+) T lymphocytes
Kasprzycka, M., Zhang, Q., Witkiewicz, A., Marzec, Michal Tomasz, Potoczek, M., Liu, X., Wang, H. Y., Milone, M., Basu, S., Mauger, J., Choi, J. K., Abrams, J. T., Hou, J. S., Rook, A. H., Vonderheid, E., Woetmann, A., Ødum, Niels & Wasik, M. A., 15 Aug 2008, In: Journal of Immunology. 181, 4, p. 2506-2512Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Differential Effects of Interleukin-2 and Interleukin-15 versus Interleukin-21 on CD4+ Cutaneous T-Cell Lymphoma Cells
Marzec, Michal Tomasz, Halasa, K., Kasprzycka, M., Wysocka, M., Liu, X., Tobias, J. W., Baldwin, D., Zhang, Q., Ødum, Niels, Rook, A. H. & Wasik, M. A., 2008, In: Cancer Research. 68, 4, p. 1083-91 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
EGFR induces expression of IRF-1 via STAT1 and STAT3 activation leading to growth arrest of human cancer cells
Andersen, P., Pedersen, M. W., Woetmann, Anders , Villingshøj, M., Stockhausen, M., Ødum, Niels & Poulsen, H. S., 2008, In: International Journal of Cancer. 122, 2, p. 342-9 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
FOXP3 positive regulatory T-cells in cutaneous T-cell lymphomas
Gjerdrum, L. M., Woetmann, Anders , Ødum, Niels & Ralfkiaer, E., 2008, In: Virchows Archiv. 452, Suppl. 1, p. S4-S4Research output: Contribution to journal › Journal article › Research › peer-review
- Published
FOXP3 positive regulatory T-cells in cutaneous and systemic CD30 positive T-cell lymphoproliferations
Gjerdrum, L. M., Woetmann, Anders , Ødum, Niels, Hother, C., Henrik-Nielsen, R., Gniadecki, R. & Ralfkiaer, E., 2008, In: European Journal of Haematology. 80, 6, p. 483-9 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Gamma c-signaling cytokines induce a regulatory T cell phenotype in malignant CD4+ T lymphocytes
Kasprzycka, M., Zhang, Q., Witkiewicz, A., Marzec, M., Potoczek, M., Liu, X., Wang, H. Y., Milone, M., Basu, S., Mauger, J., Choi, J. K., Abrams, J. T., Hou, J. S., Rook, A. H., Vonderheid, E., Woetmann, Anders , Ødum, Niels & Wasik, M. A., 2008, In: Journal of Immunology. 181, 4, p. 2506-12 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
IL-2- and IL-15-induced activation of the rapamycin-sensitive mTORC1 pathway in malignant CD4+ T lymphocytes
Marzec, Michal Tomasz, Liu, X., Kasprzycka, M., Witkiewicz, A., Raghunath, P. N., El-Salem, M., Robertson, E., Ødum, Niels & Wasik, M. A., 2008, In: Blood. 111, 4, p. 2181-9 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Malignant Tregs express low molecular splice forms of FOXP3 in Sézary syndrome
Krejsgaard, T., Gjerdrum, L. M., Ralfkiaer, E., Lauenborg, B., Eriksen, K. W., Mathiesen, A., Bovin, L. F., Gniadecki, R., Geisler, Carsten, Ryder, L. P., Zhang, Q., Wasik, M. A., Ødum, Niels & Woetmann, Anders , 2008, In: Leukemia. p. 2230-2239 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
γc-Signaling Cytokines Induce a Regulatory T Cell Phenotype in Malignant CD4+ T Lymphocytes.
Kasprzycka, M., Zhang, Q., Witkiewicz, A., Marzec, Michal Tomasz, Potoczek, M., Liu, X., Wang, H. Y., Milone, M., Basu, S., Mauger, J., Choi, J. K., Abrams, J. T., Hou, J. S., Rook, A. H., Vonderheid, E., Woetmann, A., Ødum, Niels & Wasik, M. A., 2008, In: Journal of Immunology. 181, 4, p. 2506-2512 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2007
- Published
FOXP3+ regulatory T cells in cutaneous T-cell lymphomas: association with disease stage and survival
Gjerdrum, L. M., Woetmann, Anders , Ødum, Niels, Burton, C. M., Rossen, K., Skovgaard, G. L., Ryder, L. P. & Ralfkiaer, E., 2007, In: Leukemia. 21, 12, p. 2512-2518 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Interleukin 21 therapy increases the density of tumor infiltrating CD8+ T cells and inhibits the growth of syngeneic tumors
Søndergaard, H., Frederiksen, K. S., Thygesen, P., Galsgaard, E. D., Skak, K., Kristjansen, P. E. G., Ødum, Niels & Kragh, M., 2007, In: Cancer Immunology, Immunotherapy. 56, 9, p. 1417-28 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Loss of SHP-1 tyrosine phosphatase expression correlates with the advanced stages of cutaneous T-cell lymphoma
Witkiewicz, A., Raghunath, P., Wasik, A., Junkins-Hopkins, J. M., Jones, D., Zhang, Q., Ødum, Niels & Wasik, M. A., 2007, In: Human Pathology. 38, 3, p. 462-7 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Nonmalignant T cells stimulate growth of T-cell lymphoma cells in the presence of bacterial toxins
Woetmann, Anders , Lovato, P., Eriksen, K. W., Krejsgaard, T., Labuda, T., Zhang, Q., Mathiesen, A., Geisler, Carsten, Svejgaard, A., Wasik, M. A. & Ødum, Niels, 2007, In: Blood. 109, 8, p. 3325-32 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2006
- Published
Jak3- and JNK-dependent vascular endothelial growth factor expression in cutaneous T-cell lymphoma
Krejsgaard, T., Vetter-Kauczok, C. S., Woetmann, Anders , Lovato, P., Labuda, T., Eriksen, K. W., Zhang, Q., Becker, J. C. & Ødum, Niels, 2006, In: Leukemia. 20, 10, p. 1759-66 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Multi-gene epigenetic silencing of tumor suppressor genes in T-cell lymphoma cells; delayed expression of the p16 protein upon reversal of the silencing
Nagasawa, T., Zhang, Q., Raghunath, P. N., Wong, H. Y., El-Salem, M., Szallasi, A., Marzec, Michal Tomasz, Gimotty, P., Rook, A. H., Vonderheid, E. C., Ødum, Niels & Wasik, M. A., 2006, In: Leukemia research : a Forum for Studies on Leukemia and Normal Hemopoiesis. 30, 3, p. 303-12 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
STAT3 induces transcription of the DNA methyltransferase 1 gene (DNMT1) in malignant T lymphocytes
Zhang, Q., Wang, H. Y., Woetmann, Anders , Raghunath, P. N., Ødum, Niels & Wasik, M. A., 2006, In: Blood. 108, 3, p. 1058-64 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Spironolactone induces apoptosis and inhibits NF-kappaB independent of the mineralocorticoid receptor
Sønder, S. U. S., Woetmann, Anders , Ødum, Niels & Bendtzen, K., 2006, In: Apoptosis. 11, 12, p. 2159-65 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2005
- Published
A functional polymorphism in the Eta-1 promoter is associated with allele specific binding to the transcription factor Sp1 and elevated gene expression
Hummelshoj, T., Ryder, L. P., Madsen, H. O., Ødum, Niels & Svejgaard, A., 2005, In: Molecular Immunology. 43, 7, p. 980-6 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Cancer cells become susceptible to natural killer cell killing after exposure to histone deacetylase inhibitors due to glycogen synthase kinase-3-dependent expression of MHC class I-related chain A and B
Skov, Søren, Pedersen, M. T., Andresen, Lars, Straten, P. T., Woetmann, Anders & Ødum, Niels, 2005, In: Cancer Research. 65, 23, p. 11136-45 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Constitutive SOCS-3 expression protects T-cell lymphoma against growth inhibition by IFNalpha
Brender, C., Lovato, P., Sommer, V. H., Woetmann, Anders , Mathiesen, A., Geisler, Carsten, Wasik, M. & Ødum, Niels, 2005, In: Leukemia. 19, 2, p. 209-13 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
ID: 14062
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Vitamin D up-regulates the vitamin D receptor by protecting it from proteasomal degradation in human CD4+ T cells
Research output: Contribution to journal › Journal article › Research › peer-review
Published -
425
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Vitamin D counteracts Mycobacterium tuberculosis-induced cathelicidin downregulation in dendritic cells and allows Th1 differentiation and IFNγ secretion
Research output: Contribution to journal › Journal article › Research › peer-review
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350
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STAT5 induces miR-21 expression in cutaneous T cell lymphoma
Research output: Contribution to journal › Journal article › Research › peer-review
Published