Niels Ødum
Professor
Skin Immunology Research Center
Blegdamsvej 3B, 2200 København N, 07 Bygning 7, Building: 07-12-86
Member of:
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Medforfatter til "Celleinteraktioner og regulering"
Ødum, Niels, 2000, Basal og klinisk immunologi. FADL's Forlag, p. -Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Education
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Merkel cell carcinoma-derived exosome-shuttle miR-375 induces fibroblast polarization by inhibition of RBPJ and p53
Fan, K., Spassova, I., Gravemeyer, J., Ritter, C., Horny, K., Lange, A., Gambichler, T., Ødum, Niels, Schrama, D., Schadendorf, D., Ugurel, S. & Becker, J. C., 2021, In: Oncogene. 40, p. 980–996Research output: Contribution to journal › Journal article › Research › peer-review
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MicroRNA expression in early mycosis fungoides is distinctly different from atopic dermatitis and advanced cutaneous T-cell lymphoma
Ralfkiaer, U., Lindahl, L. M., Litman, Thomas, Gjerdrum, Lise Mette Rahbek, Ahler, C. B., Gniadecki, R., Marstrand, T., Fredholm, S., Iversen, L., Wasik, M. A., Bonefeld, Charlotte Menne, Geisler, Carsten, Krejsgaard, T., Glue, C., Røpke, M. A., Woetmann, A., Skov, Lone, Grønbæk, Kirsten & Ødum, Niels, Dec 2014, In: Anticancer Research. 34, 12, p. 7207-17 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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MicroRNA-106b Regulates Expression of the Tumour Suppressors p21 and TXNIP and Promotes Tumour Cell Proliferation in Mycosis Fungoides
Lindahl, L. M., Gluud, Maria, Emmanuel, T., Thomsen, E. A., Hu, T., Rittig, A. H., Celis, P., Stolearenco, V., Krejsgaard, T., Johansen, C., Willerslev-Olsen, A., Buus, Terkild Brink, Woetmann, Anders , Aagaard, L., Geisler, Carsten, Litman, Thomas, Mikkelsen, J. G., Ødum, Niels & Iversen, L., 2020, In: Acta Dermato-Venereologica. 100, 8 p., adv00270.Research output: Contribution to journal › Journal article › Research › peer-review
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MicroRNA-93 Targets p21 and Promotes Proliferation in Mycosis Fungoides T Cells
Gluud, Maria, Fredholm, S., Blümel, E., Willerslev-Olsen, A., Buus, Terkild Brink, Nastasi, C., Krejsgaard, T., Bonefeld, Charlotte Menne, Woetmann, Anders , Iversen, L., Litman, Thomas, Geisler, Carsten, Ødum, Niels & Lindahl, L. M., 2021, In: Dermatology. 237, p. 277–282Research output: Contribution to journal › Journal article › Research › peer-review
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MicroRNAs in the pathogenesis, diagnosis, prognosis and targeted treatment of cutaneous T-cell lymphomas
Gluud, Maria, Willerslev-Olsen, A., Gjerdrum, Lise Mette Rahbek, Lindahl, L. M., Buus, Terkild Brink, Andersen, Mads Hald, Bonefeld, Charlotte Menne, Krejsgaard, T., Litvinov, I. V., Iversen, L., Becker, J. C., Persson, J. L., Koralov, S. B., Litman, Thomas, Geisler, Carsten, Woetmann, Anders & Ødum, Niels, 2020, In: Cancers. 12, 5, 18 p., 1229.Research output: Contribution to journal › Review › Research › peer-review
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Midline 1 controls polarization and migration of murine cytotoxic T cells
Boding, L., Hansen, A. K., Nielsen, M. M., Meroni, G., Braunstein, T. H., Woetmann, A., Ødum, Niels, Bonefeld, Charlotte Menne & Geisler, Carsten, Dec 2014, In: Immunity, Inflammation and Disease. 2, 4, p. 262-71 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Midline 1 directs lytic granule exocytosis and cytotoxicity of mouse killer T cells
Boding, L., Hansen, A. K., Meroni, G., Johansen, B. B., Braunstein, T. H., Bonefeld, Charlotte Menne, Kongsbak-Wismann, Martin, Jensen, Benjamin Anderschou Holbech, Woetmann, A., Thomsen, Allan Randrup, Ødum, Niels, von Essen, Marina Rode & Geisler, Carsten, 12 Jul 2014, In: European Journal of Immunology. 44, 10, p. 3109-3118 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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MspI polymorphism in the human interleukin 6 (IL 6) gene
Fugger, L., Morling, Niels, Bendtzen, K., Ryder, L., Odum, N., Georgsen, J., Svejgaard, A. & Ødum, Niels, 1989, In: Nucleic Acids Research. 17, 11, p. 4419Research output: Contribution to journal › Journal article › Research › peer-review
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Multi-gene epigenetic silencing of tumor suppressor genes in T-cell lymphoma cells; delayed expression of the p16 protein upon reversal of the silencing
Nagasawa, T., Zhang, Q., Raghunath, P. N., Wong, H. Y., El-Salem, M., Szallasi, A., Marzec, Michal Tomasz, Gimotty, P., Rook, A. H., Vonderheid, E. C., Ødum, Niels & Wasik, M. A., 2006, In: Leukemia research : a Forum for Studies on Leukemia and Normal Hemopoiesis. 30, 3, p. 303-12 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Multilevel dysregulation of STAT3 activation in anaplastic lymphoma kinase-positive T/null-cell lymphoma
Zhang, Q., Raghunath, P. N., Xue, L., Majewski, M., Carpentieri, D. F., Ødum, Niels, Morris, S., Skorski, T. & Wasik, M. A., 2002, In: Journal of Immunology. 168, 1, p. 466-74 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Multimodal single-cell analysis of cutaneous T-cell lymphoma reveals distinct subclonal tissue-dependent signatures
Herrera, A., Cheng, A., Mimitou, E. P., Seffens, A., George, D., Bar-Natan, M., Heguy, A., Ruggles, K. V., Scher, J. U., Hymes, K., Latkowski, J. A., Ødum, Niels, Kadin, M. E., Ouyang, Z., Geskin, L. J., Smibert, P., Buus, Terkild Brink & Koralov, S. B., 2021, In: Blood. 138, 16, p. 1456-1464 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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NKG2D-Dependent Activation of Dendritic Epidermal T cells in Contact Hypersensitivity
Nielsen, M. M., Dyring-Andersen, Beatrice, Schmidt, J. D., Witherden, D., Lovato, P., Woetmann, Anders , Ødum, Niels, Poulsen, Steen Seier, Havran, W. L., Geisler, Carsten & Bonefeld, Charlotte Menne, May 2015, In: Journal of Investigative Dermatology. 135, 5, p. 1311-19 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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New DPB1 alleles
Madsen, H. O., Ryder, L. P., Fugger, L., Ødum, Niels, Jakobsen, B. K. & Svejgaard, A., 1992, In: HLA. 39, 2, p. 102-3 1 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Nonmalignant T cells stimulate growth of T-cell lymphoma cells in the presence of bacterial toxins
Woetmann, Anders , Lovato, P., Eriksen, K. W., Krejsgaard, T., Labuda, T., Zhang, Q., Mathiesen, A., Geisler, Carsten, Svejgaard, A., Wasik, M. A. & Ødum, Niels, 2007, In: Blood. 109, 8, p. 3325-32 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Normal T and B Cell Responses Against SARS-CoV-2 in a Family With a Non-Functional Vitamin D Receptor: A Case Report
Kongsbak-Wismann, Martin, Al-Jaberi, F. A. H., Schmidt, J. D., Ghanizada, M., Hansen, Cecilie Bo, Lopez, D. V., Woetmann, Anders , Ødum, Niels, Bonefeld, Charlotte Menne, Buus, Anette Stryhn, Garred, Peter, Buus, Søren & Geisler, Carsten, 2021, In: Frontiers in Immunology. 12, 758154.Research output: Contribution to journal › Journal article › Research › peer-review
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Notch 1 as a potential therapeutic target in cutaneous T-cell lymphoma
Kamstrup, M. R., Gjerdrum, Lise Mette Rahbek, Biskup, E. U., Lauenborg, B. T., Ralfkiær, E. M., Woetmann, Anders , Ødum, Niels & Gniadecki, R., 7 Jan 2010, In: Blood. 116, 14, p. 2504-12Research output: Contribution to journal › Journal article › Research › peer-review
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OMIP‐057: Mouse γδ T‐Cell Development Characterized by a 14 Color Flow Cytometry Panel
Buus, Terkild Brink, Jee, Mia Hamilton & Ødum, Niels, 12 Apr 2019, In: Cytometry. Part A. 95, 7, p. 726-729Research output: Contribution to journal › Journal article › Research › peer-review
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Occurrence of anti-HTLV-III antibodies in Danish high-risk homosexuals in 1982-83--seroconversion rate and risk of AIDS
Hofmann, B., Platz, P., Ødum, Niels, Ryder, L. P., Svejgaard, A., Pedersen, N. S., Nielsen, J. O., Faber, V., Sprechler, H. H. & Oehlenschlager, J., 1986, In: AIDS Research. 2, 1, p. 1-3 2 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Old Sins Cast Long Shadows: News on Staphylococcus aureus in Cutaneous T Cell Lymphoma
Guenova, E. & Ødum, Niels, 2023, In: Journal of Investigative Dermatology. 144, 1, p. 8-10 3 p.Research output: Contribution to journal › Letter › Research › peer-review
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Oligonucleotide fishing for STAT6: cross-talk between IL-4 and chemokines.
Eriksen, K. W., Nielsen, M., Kaltoft, K., Svejgaard, A., Nissen, Mogens Holst, Röpke, C. & Ødum, Niels, 2001, In: Experimental and Clinical Immunogenetics. 18, 4, p. 233-41 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Omalizumab serum levels predict treatment outcomes in patients with chronic spontaneous urticaria: A three months prospective study
Noshela Ghazanfar, M., Bartko, E. A., Arildsen, Nicolai Skovbjerg, Poulsen, Lars K., Jensen, B. M., Enevold, C., Holm, J. G., Woetmann, Anders , Ødum, Niels & Thomsen, Simon Francis, 2022, In: Clinical and Experimental Allergy. 52, 4 p.Research output: Contribution to journal › Comment/debate › Research
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Oncogenic kinase NPM/ALK induces expression of HIF1 alpha mRNA
Marzec, Michal Tomasz, Liu, X., Wong, W., Yang, Y., Pasha, T., Kantekure, K., Zhang, P., Woetmann, Anders , Cheng, M., Ødum, Niels & Wasik, M. A., 2011, In: Oncogene. 30, 11, p. 1372-1378 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Oncogenic tyrosine kinase NPM-ALK induces expression of the growth-promoting receptor ICOS
Zhang, Q., Wang, H., Kantekure, K., Paterson, J. C., Liu, X., Schaffer, A., Paulos, C., Milone, M. C., Ødum, Niels, Turner, S., Marafioti, T. & Wasik, M. A., 15 Sep 2011, In: Blood. 118, 11, p. 3062-3071 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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PKC-θ exists in an oxidized inactive form in naive human T cells
von Essen, Marina Rode, Kongsbak-Wismann, Martin, Levring, T. B., Hansen, A. K., Boding, L., Lauritsen, J. P. H., Woetmann, Anders , Baier, G., Ødum, Niels, Bonefeld, Charlotte Menne & Geisler, Carsten, Jun 2013, In: European Journal of Immunology. 43, 6, p. 1659-66 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Pathogenic CD8+ epidermis-resident memory T cells displace dendritic epidermal T cells in allergic dermatitis
Ø Gadsbøll, A., Jee, Mia Hamilton, Funch, Anders Boutrup, Alhede, M., Mraz, Veronika, Weber, Julie Friis, Callender, L. A., Carroll, E. C., Bjarnsholt, Thomas, Woetmann, Anders , Ødum, Niels, Thomsen, Allan Randrup, Johansen, Jeanne Duus, Henson, S. M., Geisler, Carsten & Bonefeld, Charlotte Menne, 2020, In: The Journal of Investigative Dermatology. 140, 4, p. 806-815.e5Research output: Contribution to journal › Journal article › Research › peer-review
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Peptide vaccination activating Galectin-3-specific T cells offers a novel means to target Galectin-3-expressing cells in the tumor microenvironment
Bendtsen, S. K., Perez Penco, Maria, Hübbe, M. L., Martinenaite, E., Orebo Holmström, M., Weis-Banke, S. E., Grønne Dahlager Jørgensen, N., Jørgensen, M. A., Munir Ahmad, S., Jensen, K. M., Friese, C., Lundsager, M. T., Johansen, A. Z., Carretta, M., Ødum, Niels, Met, Özcan, Svane, Inge Marie, Madsen, Daniel Hargbøl & Andersen, Mads Hald, 2022, In: OncoImmunology. 11, 1, 2026020.Research output: Contribution to journal › Journal article › Research › peer-review
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Peptidylarginine Deiminase 2 Gene Polymorphisms in Subjects with Periodontitis Predispose to Rheumatoid Arthritis
Massarenti, Laura, Enevold, C., Damgaard, D., Hansen, Peter Riis, Frisch, M., Ødum, Niels, Jacobsen, Søren & Nielsen, Claus Henrik, 2022, In: International Journal of Molecular Sciences. 23, 17, 10 p., 9536.Research output: Contribution to journal › Journal article › Research › peer-review
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Peptidylarginine deiminase-4 gene polymorphisms are associated with systemic lupus erythematosus and lupus nephritis
Massarenti, Laura, Enevold, C., Damgaard, D., Ødum, Niels, Nielsen, Claus Henrik & Jacobsen, Søren, 2019, In: Scandinavian Journal of Rheumatology. 48, 2, p. 133-140Research output: Contribution to journal › Journal article › Research › peer-review
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Phenotypic plasticity of malignant T cells in blood and skin of a Sézary syndrome patient revealed by single cell transcriptomics
Peiffer, L., Gambichler, T., Buus, Terkild Brink, Horny, K., Gravemeyer, J., Furtmann, F., Spassova, I., Kubat, L., Susok, L., Stranzenbach, R., Srinivas, N., Ødum, Niels & Becker, J. C., 2023, In: Frontiers in Oncology. 13, 1090592.Research output: Contribution to journal › Journal article › Research › peer-review
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Polymorphisms of the T cell receptor CD3delta and CD3varepsilon chains affect anti-CD3 antibody binding and T cell activation
Boding, L., Nielsen, M. W., Bonefeld, Charlotte Menne, von Essen, Marina Rode, Nielsen, B. L., Lauritsen, J. P. H., Hansen, A. K., Nielsen, M. M., Kongsbak, M., Rubin, M., Vennegaard, M. T., Ødum, Niels & Geisler, Carsten, 2010, In: Molecular Immunology. 47, 15, p. 2450-7 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- E-pub ahead of print
Pre-existing inflammation reduces the response to contact allergens in Tmem79-deficient mice
Jee, Mia Hamilton, Funch, Anders Boutrup, Weber, Julie Friis, Yeung, Kelvin, Mraz, Veronika, Gadsbøll, A. Ø., Song, T., Woetmann, Anders , Ødum, Niels, Johansen, Jeanne Duus, Geisler, Carsten & Bonefeld, Charlotte Menne, 17 Feb 2024, (E-pub ahead of print) In: Allergy: European Journal of Allergy and Clinical Immunology. 4 p.Research output: Contribution to journal › Comment/debate › Research › peer-review
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Prognostic miRNA classifier in early-stage mycosis fungoides: development and validation in a Danish nationwide study
Lindahl, L. M., Besenbacher, S., Rittig, A. H., Celis, P., Willerslev-Olsen, A., Gjerdrum, Lise Mette Rahbek, Krejsgaard, T., Johansen, C., Litman, Thomas, Woetmann, Anders , Ødum, Niels & Iversen, L., 2018, In: Blood. 131, 7, p. 759-770 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Proinflammatory biomarkers are associated with prediabetes in patients with schizophrenia
Mller, M., Fredholm, S., Jensen, M. E., Wörtwein, Gitta, Larsen, J. R., Vilsbøll, Tina, Ødum, Niels & Fink-Jensen, Anders, 2022, In: CNS Spectrums. 27, 3, 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Prolongation of bleeding time and inhibition of platelet aggregation by low-dose acetylsalicylic acid in patients with cerebrovascular disease
Boysen, G., Boss, A. H., Ødum, Niels & Olsen, J. S., 1984, In: Stroke. 15, 2, p. 241-3 2 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Proteasomal targeting and minigene repetition improve cell-surface presentation of a transfected, modified melanoma tumour antigen
Rasmussen, A. B., Zocca, M., Bonefeld, Charlotte Menne, von Essen, Marina Rode, Lauritsen, J. P., Tomra, S., Ødum, Niels & Geisler, Carsten, 2004, In: Scandinavian Journal of Immunology. 59, 2, p. 220-7 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Protein phosphatase 2A (PP2A) regulates interleukin-4-mediated STAT6 signaling
Woetmann, Anders , Brockdorff, J., Lovato, P., Nielsen, M., Leick, V., Rieneck, K., Svejgaard, A., Geisler, Carsten & Ødum, Niels, 2002, In: Journal of Biological Chemistry. 278, 5, p. 2787-91 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Protein phosphates 2A (PP2A) regulates IL-4- mediated STAT6 signalling
Woetmann, Anders , Nielsen, M., Brockdorff, J., Leick, V., Rieneck, K., Bendtzen, K., Geisler, C. & Ødum, Niels, 2003, In: Journal of Biological Chemistry. 278, p. 2787-2791Research output: Contribution to journal › Journal article › Research › peer-review
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Radically altered T cell receptor signaling in glycopeptide-specific T cell hybridoma induced by antigen with minimal differences in the glycan group
Jensen, T., Nielsen, M., Gad, M., Hansen, P., Komba, S., Meldal, M., Ødum, Niels & Werdelin, O., 2001, In: European Journal of Immunology. 31, 11, p. 3197-206 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Rapid allergen-induced interleukin-17 and interferon-γ secretion by skin-resident memory CD8(+) T cells
Schmidt, J. D., Ahlström, M. G., Johansen, Jeanne Duus, Dyring-Andersen, Beatrice, Agerbeck, C., Nielsen, M. M., Poulsen, Steen Seier, Woetmann, Anders , Ødum, Niels, Thomsen, Allan Randrup, Geisler, Carsten & Bonefeld, Charlotte Menne, 2017, In: Contact Dermatitis. 76, 4, p. 218–227Research output: Contribution to journal › Journal article › Research › peer-review
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Rapid tyrosine phosphorylation of Lck following ligation of the tumor-associated cell surface molecule A6H
Labuda, T., Gerwien, J., Ødum, Niels & Dohlsten, M., 1999, In: International Immunology. 11, 3, p. 427-33 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Regulation of vascular endothelial growth factor in prostate cancer
de Brot, S., Ntekim, A., Cardenas, R., James, V., Allegrucci, C., Heery, D. M., Bates, D. O., Ødum, Niels, Persson, J. L. & Mongan, N. P., Jun 2015, In: Endocrine - Related Cancer. 22, 3, p. R107-R123 17 p.Research output: Contribution to journal › Review › Research › peer-review
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Regulatory T cells and immunodeficiency in mycosis fungoides and Sézary syndrome
Krejsgaard, T. F., Ødum, Niels, Geisler, Carsten, Wasik, M. A. & Woetmann, Anders , 2012, In: Leukemia. 26, p. 424-432 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Repeated immunization with ATRA-containing liposomal adjuvant transdifferentiates Th17 cells to a Tr1-like phenotype
Wørzner, K., Zimmermann, J., Buhl, R., Desoi, A., Christensen, D., Dietrich, J., Nguyen, N. D. N. T., Lindenstrøm, T., Woodworth, J. S., Alhakeem, R. S., Yu, S., Ødum, Niels, Mortensen, R., Ashouri, J. F. & Pedersen, Gabriel Kristian, Apr 2024, In: Journal of Autoimmunity. 144, 11 p., 103174.Research output: Contribution to journal › Journal article › Research › peer-review
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Response to Shawn G. Kwatra.
Krejsgaard, T. F., Woetmann, Anders & Ødum, Niels, 2011, In: Journal of Investigative Dermatology. 131, 9, p. 1955–1956 2 p.Research output: Contribution to journal › Comment/debate › Research › peer-review
Restriction fragment length polymorphism of the HLA-DP subregion and correlations to HLA-DP phenotypes
Hyldig-Nielsen, J. J., Morling, Niels, Ødum, Niels, Ryder, L. P., Platz, P., Jakobsen, B. & Svejgaard, A., 1987, In: Proceedings of the National Academy of Science of the United States of America. 84, 6, p. 1644-8 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Restriction fragment polymorphism (RFLP) of a "new" HLA-DP specificity, CDP-HEI
Hyldig-Nielsen, J. J., Ødum, Niels, Morling, Niels & Svejgaard, A., 1988, In: HLA. 31, 3, p. 161-3 2 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Role of B-cells in mycosis fungoides
Nielsen, Pia Rude, Eriksen, J. O., Sørensen, M. D., Wehkamp, U., Lindahl, L. M., Bzorek, M., Iversen, L., Woetmann, Anders , Ødum, Niels, Litman, Thomas & Gjerdrum, Lise Mette Rahbek, 2021, In: Acta Dermato-Venereologica. 101, 3, adv00413.Research output: Contribution to journal › Journal article › Research › peer-review
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Role of Dysregulated Cytokine Signaling and Bacterial Triggers in the Pathogenesis of Cutaneous T-Cell Lymphoma
Fanok, M. H., Sun, A., Fogli, L. K., Narendran, V., Eckstein, M., Kannan, K., Dolgalev, I., Lazaris, C., Heguy, A., Laird, M. E., Sundrud, M. S., Liu, C., Kutok, J., Lacruz, R. S., Latkowski, J. A., Aifantis, I., Ødum, Niels, Hymes, K. B., Goel, S. & Koralov, S. B., 2018, In: Journal of Investigative Dermatology. 138, 5, p. 1116-1125 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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SATB1 in malignant T cells
Fredholm, S. M., Willerslev-Olsen, A., Met, Ö., Kubat, L., Gluud, M., Mathiasen, S. L., Friese, C., Blümel, E., Petersen, D. L., Hu, T., Nastasi, C., Lindahl, L. M., Buus, T. B., Krejsgaard, T. F., Wasik, M. A., Kopp, K. L. M., Koralov, S. B., Persson, J. L., Bonefeld, C. M., Geisler, C. & 4 others, , 2018, In: The Journal of Investigative Dermatology. 138, 8, p. 1805-1815 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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SHP2 regulates IL-2 induced MAPK activation, but not Stat3 or Stat5 tyrosine phosphorylation, in cutaneous T cell lymphoma cells
Lundin Brockdorff, J., Woetmann, Anders , Mustelin, T., Kaltoft, K., Zhang, Q., Wasik, M. A., Röpke, C. & Ødum, Niels, 2002, In: Cytokine. 20, 4, p. 141-7 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
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SOCS5 is expressed in primary B and T lymphoid cells but is dispensable for lymphocyte production and function
Brender, C., Columbus, R., Metcalf, D., Handman, E., Starr, R., Huntington, N., Tarlinton, D., Ødum, Niels, Nicholson, S. E., Nicola, N. A., Hilton, D. J. & Alexander, W. S., 2004, In: Molecular and Cellular Biology. 24, 13, p. 6094-103 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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STAT3 activation and infiltration of eosinophil granulocytes in mycosis fungoides
Fredholm, S., Gjerdrum, Lise Mette Rahbek, Willerslev-Olsen, A., Petersen, D. L., Nielsen, I. Ø., Kauczok, C., Wobser, M., Ralfkiaer, U., Bonefeld, Charlotte Menne, Wasik, M. A., Krejsgaard, T., Geisler, Carsten, Ralfkiaer, E., Gniadecki, R., Woetmann, Anders & Ødum, Niels, 2014, In: Anticancer Research. 34, 10, p. 5277-5286 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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STAT3 dysregulation in mature T and NK cell lymphomas
Seffens, A., Herrera, A., Tegla, C., Buus, Terkild Brink, Hymes, K. B., Ødum, Niels, Geskin, L. J. & Koralov, S. B., 2019, In: Cancers. 11, 11, 17 p., 1711.Research output: Contribution to journal › Review › Research › peer-review
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STAT3 induces transcription of the DNA methyltransferase 1 gene (DNMT1) in malignant T lymphocytes
Zhang, Q., Wang, H. Y., Woetmann, Anders , Raghunath, P. N., Ødum, Niels & Wasik, M. A., 2006, In: Blood. 108, 3, p. 1058-64 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
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STAT3-mediated constitutive expression of SOCS-3 in cutaneous T-cell lymphoma
Brender, C., Nielsen, M., Kaltoft, K., Mikkelsen, G., Zhang, Q., Wasik, M., Billestrup, N. & Ødum, Niels, 2001, In: Blood. 97, 4, p. 1056-62 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
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STAT3/5-dependent IL9 overexpression contributes to neoplastic cell survival in mycosis fungoides
Vieyra-Garcia, P. A., Wei, T., Naym, D. G., Fredholm, S., Fink-Puches, R., Cerroni, L., Ødum, Niels, O'Malley, J. T., Gniadecki, R. & Wolf, P., Jul 2016, In: Clinical Cancer Research. 22, 13, p. 3328-3339 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
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STAT5 induces miR-21 expression in cutaneous T cell lymphoma
Lindahl, L. M., Fredholm, S., Joseph, C. V., Nielsen, B. S., Jønson, L., Willerslev-Olsen, A., Gluud, M., Blümel, E., Petersen, D. L., Sibbesen, N., Hu, T., Nastasi, C., Krejsgaard, T., Jæhger, D., Persson, J. L., Mongan, N., Wasik, M. A., Litvinov, I. V., Sasseville, D., Koralov, S. B. & 6 others, , 2016, In: OncoTarget. 7, 29, p. 45730-45744 15 p.Research output: Contribution to journal › Journal article › Research › peer-review
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STAT5-mediated expression of oncogenic miR-155 in cutaneous T-cell lymphoma
Kopp, K. L., Ralfkiaer, U., Gjerdrum, Lise Mette Rahbek, Helvad, R., Pedersen, I. H., Litman, Thomas, Jønson, L., Hagedorn, P. H., Krejsgaard, T., Gniadecki, R., Bonefeld, Charlotte Menne, Skov, Lone, Geisler, Carsten, Wasik, M. A., Ralfkiaer, E., Ødum, Niels & Woetmann, A., 2013, In: Cell Cycle. 12, 12, p. 1939-47 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Selective modulation of the CD4 molecular complex by Pseudomonas aeruginosa alkaline protease and elastase
Pedersen, Bente Klarlund, Kharazmi, A., Theander, Thor Grundtvig, Ødum, Niels, Andersen, V. & Bendtzen, K., 1987, In: Scandinavian Journal of Immunology. 26, 1, p. 91-4 3 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Signal transduction by HLA class II antigens expressed on activated T cells
Ødum, Niels, Martin, P. J., Schieven, G. L., Hansen, J. A. & Ledbetter, J. A., 1991, In: European Journal of Immunology. 21, 1, p. 123-9 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Signal transduction by HLA class II molecules in human T cells: induction of LFA-1-dependent and independent adhesion
Ødum, Niels, Yoshizumi, H., Okamoto, Y., Kamikawaji, N., Kimura, A., Nishimura, Y. & Sasazuki, T., 1992, In: Human Immunology. 35, 2, p. 71-84 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Signal transduction by HLA-DR is mediated by tyrosine kinase(s) and regulated by CD45 in activated T cells
Ødum, Niels, Martin, P. J., Schieven, G. L., Norris, N. A., Grosmaire, L. S., Hansen, J. A. & Ledbetter, J. A., 1991, In: Human Immunology. 32, 2, p. 85-94 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Simultaneous inhibition of mTOR-containing complex 1 (mTORC1) and MNK induces apoptosis of cutaneous T-cell lymphoma (CTCL) cells
Marzec, Michal Tomasz, Liu, X., Wysocka, M., Rook, A. H., Ødum, Niels & Wasik, M. A., 16 Sep 2011, In: PLoS ONE. 6, 9, 8 p., e24849.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Single-cell heterogeneity in Sézary syndrome.
Buus, Terkild Brink, Willerslev-Olsen, A., Fredholm, S. M., Blümel, E., Nastasi, C., Gluud, Maria, Hu, T., Lindahl, L. M., Iversen, L., Fogh, H., Gniadecki, R., Litvinov, I. V., Persson, J. L., Bonefeld, Charlotte Menne, Geisler, Carsten, Christensen, Jan Pravsgaard, Krejsgaard, T. F., Litman, Thomas, Woetmann, Anders & Ødum, Niels, 2018, In: Blood advances. 2, 16, p. 2115-2126Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Specific proliferative response of human lymphocytes to purified soluble antigens from Plasmodium falciparum in vitro cultures and to antigens from malaria patients' sera
Bygbjerg, Ib Christian, Jepsen, S., Theander, Thor Grundtvig & Ødum, Niels, 1985, In: Clinical and Experimental Immunology. 59, 2, p. 421-6 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Spironolactone induces apoptosis and inhibits NF-kappaB independent of the mineralocorticoid receptor
Sønder, S. U. S., Woetmann, Anders , Ødum, Niels & Bendtzen, K., 2006, In: Apoptosis. 11, 12, p. 2159-65 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Spontaneous interleukin-5 production in cutaneous T-cell lymphoma lines is mediated by constitutively activated Stat3
Nielsen, M., Nissen, Mogens Holst, Gerwien, J., Zocca, M., Rasmussen, H. M., Nakajima, K., Röpke, C., Geisler, Carsten, Kaltoft, K. & Ødum, Niels, 2002, In: Blood. 99, 3, p. 973-7 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Stahpylococcal enterotoxin A modulates IL-15 responses in human T cells
Gerwien, J., Nielsen, M., Pedersen, M. N., Svejgaard, A., Röpke, C. & Ødum, Niels, 1998, In: HLA. 51, p. 164-173Research output: Contribution to journal › Journal article › Research
- Published
Staphylococcal alpha-toxin tilts the balance between malignant and non-malignant CD4+ T cells in cutaneous T-cell lymphoma
Blümel, E., Willerslev-Olsen, A., Gluud, Maria, Lindahl, L. M., Fredholm, S., Nastasi, C., Krejsgaard, T., Surewaard, B. G. J., Koralov, S. B., Hu, T., Persson, J. L., Bonefeld, Charlotte Menne, Geisler, Carsten, Iversen, L., Becker, J. C., Andersen, Mads Hald, Woetmann, Anders , Buus, Terkild Brink & Ødum, Niels, 2019, In: OncoImmunology. 8, 11, 7 p., e1641387.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Staphylococcal enterotoxin A (SEA) stimulates STAT3 activation and IL-17 expression in cutaneous T-cell lymphoma
Willerslev-Olsen, A., Krejsgaard, T., Lindahl, L. M., Litvinov, I. V., Fredholm, S., Petersen, D. L., Nastasi, C., Gniadecki, R., Mongan, N. P., Sasseville, D., Wasik, M. A., Bonefeld, Charlotte Menne, Geisler, Carsten, Woetmann, Anders , Iversen, L., Kilian, M., Koralov, S. B. & Ødum, Niels, 10 Mar 2016, In: Blood. 127, 10, p. 1287-1296 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Staphylococcal enterotoxins modulate interleukin 2 receptor expression and ligand-induced tyrosine phosphorylation of the Janus protein-tyrosine kinase 3 (Jak3) and signal transducers and activators of transcription (Stat proteins)
Nielsen, M., Svejgaard, A., Röpke, C., Nordahl, M. & Ødum, Niels, 1995, In: Proceedings of the National Academy of Science of the United States of America. 92, 24, p. 10995-9 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Staphylococcal enterotoxins stimulate lymphoma-associated immune dysregulation
Krejsgaard, T. F., Willerslev-Olsen, A., Lindahl, L. M., Bonefeld, Charlotte Menne, Koralov, S. B., Geisler, Carsten, Wasik, M. A., Gniadecki, R., Kilian, M., Iversen, L., Woetmann, Anders & Ødum, Niels, 2014, In: Blood. 124, 5, p. 761-70 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Staphylococcus aureus Induces Signal Transducer and Activator of Transcription 5‒Dependent miR-155 Expression in Cutaneous T-Cell Lymphoma
Willerslev-Olsen, A., Gjerdrum, Lise Mette Rahbek, Lindahl, L. M., Buus, Terkild Brink, Pallesen, E. M. H., Gluud, Maria, Bzorek, M., Nielsen, B. S., Kamstrup, M. R., Rittig, A. H., Bonefeld, Charlotte Menne, Krejsgaard, T., Geisler, Carsten, Koralov, S. B., Litman, Thomas, Becker, J. C., Woetmann, Anders , Iversen, L. & Ødum, Niels, 2021, In: Journal of Investigative Dermatology. 141, 10, p. 2449-2458Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Stimulation of AIDS lymphocytes with calcium ionophore (A23187) and phorbol ester (PMA): studies of cytoplasmic free Ca, IL-2 receptor expression, IL-2 production, and proliferation
Hofmann, B., Moller, J., Langhoff, E., Jakobsen, K. D., Odum, N., Dickmeiss, E., Ryder, L. P., Thastrup, O., Scharff, O., Foder, B. & Ødum, Niels, 1989, In: Cellular Immunology. 119, 1, p. 14-21 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Superantigen and HLA-DR ligation induce phospholipase-C gamma 1 activation in class II+ T cells
Kanner, S. B., Ødum, Niels, Grosmaire, L., Masewicz, S., Svejgaard, A. & Ledbetter, J. A., 1992, In: Journal of Immunology. 149, 11, p. 3482-8 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Superantigen presentation by human retinal pigment epithelial cells to T cells is dependent on CD2-CD58 and CD18-CD54 molecule interactions.
Jørgensen, A., Junker, N., Kaestel, C. G., Liang, Y., Wiencke, A., la Cour, M., Lui, G. M., Ødum, Niels, Nissen, Mogens Holst & Röpke, C., 2001, In: Experimental Eye Research. 73, 5, p. 723-33 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Suppressed microRNA-195-5p expression in mycosis fungoides promotes tumor cell proliferation
Rittig, A. H., Johansen, C., Celis, P., Ødum, Niels, Litman, Thomas, Woetmann, Anders , Lindahl, L. M. & Iversen, L., 2021, In: Experimental Dermatology. 30, 8, p. 1141-1149Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Suppression of parasite-specific response in Plasmodium falciparum malaria. A longitudinal study of blood mononuclear cell proliferation and subset composition
Theander, Thor Grundtvig, Bygbjerg, Ib Christian, Andersen, B. J., Jepsen, S., Kharazmi, A. & Ødum, Niels, 1986, In: Scandinavian Journal of Immunology. 24, 1, p. 73-81 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
TCR comodulation of nonengaged TCR takes place by a protein kinase C and CD3 gamma di-leucine-based motif-dependent mechanism
Bonefeld, Charlotte Menne, Rasmussen, B. A., Lauritsen, J. P., von Essen, Marina Rode, Ødum, Niels, Andersen, P. S. & Geisler, Carsten, 2003, In: Journal of Immunology. 171, 6, p. 3003-9 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
TCR down-regulation boosts T-cell-mediated cytotoxicity and protection against poxvirus infections
Hansen, A. K., Regner, M., Bonefeld, Charlotte Menne, Boding, L., Kongsbak-Wismann, Martin, Ødum, Niels, Müllbacher, A., Geisler, Carsten & von Essen, Marina Rode, 2011, In: European Journal of Immunology. 41, 7, p. 1948-1957 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
TCR down-regulation controls T cell homeostasis
Boding, L., Bonefeld, Charlotte Menne, Nielsen, B. L., Lauritsen, J. P. H., von Essen, Marina Rode, Hansen, A. K., Larsen, J. M., Nielsen, M. M., Ødum, Niels & Geisler, Carsten, 2009, In: Journal of Immunology. 183, 8, p. 4994-5005 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
TCR down-regulation controls virus-specific CD8+ T cell responses
Bonefeld, Charlotte Menne, Haks, M., Nielsen, B., von Essen, Marina Rode, Boding, L., Hansen, A. K., Larsen, J. M., Ødum, Niels, Krimpenfort, P., Kruisbeek, A., Christensen, Jan Pravsgaard, Thomsen, Allan Randrup & Geisler, Carsten, 1 Dec 2009, In: Journal of Immunology. 181, 11, p. 7786-7799 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
TGFβ-derived immune modulatory vaccine: targeting the immunosuppressive and fibrotic tumor microenvironment in a murine model of pancreatic cancer
Perez Penco, Maria, Weis-Banke, S. E., Schina, A., Siersbæk, M., Hübbe, M. L., Jørgensen, M. A., Lecoq, I., Lara De La Torre, L., Bendtsen, S. K., Martinenaite, E., Holmström, M. O., Madsen, Daniel Hargbøl, dqp123, dqp123, Ødum, Niels, Grøntved, L. & Andersen, Mads Hald, 2022, In: Journal for ImmunoTherapy of Cancer. 10, 12, 15 p., e005491.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Technical aspects of typing for HLA-DP alleles using allele-specific DNA in vitro amplification and sequence-specific oligonucleotide probes. Detection of single base mismatches
Fugger, L., Morling, Niels, Ryder, L. P., Svejgaard, A. & Ødum, Niels, 1990, In: Journal of Immunological Methods. 129, 2, p. 175-85 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The CC-chemokine receptor 5 (CCR5) is a marker of, but not essential for the development of human Th1 cells
Ødum, Niels, Bregenholt, S., Eriksen, K. W., Skov, S., Ryder, L. P., Bendtzen, K., Van Neerven, R. J., Svejgaard, A. & Garred, Peter, 1999, In: HLA. 54, 6, p. 572-7 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The CC-chemokine receptor 5 is a marker of, but not essential for the development of human TH1 cells
Ødum, Niels, Bregenholt, S., Eriksen, K., Skov, S., Ryder, L. P., Bendtzen, K., van Nerveen, R. J. J., Svejgaard, A. & Garred, P., 1999, In: HLA. 54, p. 572-577Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The CD3 gamma leucine-based receptor-sorting motif is required for efficient ligand-mediated TCR down-regulation
von Essen, Marina Rode, Bonefeld, Charlotte Menne, Nielsen, B. L., Lauritsen, J. P. H., Dietrich, J., Andersen, P. S., Karjalainen, K., Ødum, Niels & Geisler, Carsten, 2002, In: Journal of Immunology. 168, 9, p. 4519-23 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The Escherichia coli protein toxin cytotoxic necrotizing factor 1 induces epithelial mesenchymal transition
Fabbri, A., Travaglione, S., Rosadi, F., Ballan, G., Maroccia, Z., Giambenedetti, M., Guidotti, M., Ødum, Niels, Krejsgaard, T. & Fiorentini, C., 2020, In: Cellular Microbiology. 22, 2, e13138.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The Expression of IL-21 Is Promoted by MEKK4 in Malignant T Cells and Associated with Increased Progression Risk in Cutaneous T-Cell Lymphoma
Fredholm, S., Litvinov, I. V., Mongan, N. P., Schiele, S., Willerslev-Olsen, A., Petersen, D. L., Krejsgaard, T., Sibbesen, N., Nastasi, C., Bonefeld, Charlotte Menne, Persson, J. L., thor Straten, E. P., Andersen, Mads Hald, Koralov, S. B., Wasik, M. M., Geisler, Carsten, Sasseville, D., Woetmann, Anders & Ødum, Niels, 2016, In: Journal of Investigative Dermatology. 136, 4, p. 866-869 4 p.Research output: Contribution to journal › Comment/debate › Research › peer-review
- Published
The HLA-DP polymorphism in Denmark investigated by local and international PLT reagents. Definition of two "new" DP antigens
Ødum, Niels, Hartzman, R., Jakobsen, B. K., Morling, Niels, Platz, P., Robbins, F. M., Ryder, L. P. & Svejgaard, A., 1986, In: HLA. 28, 2, p. 105-18 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
The Immunodeficiency of Bone Marrow-Transplanted Patients: The Effect of Patient Lymphocytes on the Response of Donor Lymphocytes to Mitogens and Allogeneic Cells
Ødum, Niels, Hofmann, B., Platz, P., Ryder, L. P., Langhoff, E., Jakobsen, B. K., Svejgaard, A. & Jacobsen, N., 1985, In: Scandinavian Journal of Immunology. 22, 3, p. 259-266 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The Thioredoxin-Interacting Protein TXNIP Is a Putative Tumour Suppressor in Cutaneous T-Cell Lymphoma
Stolearenco, V., Levring, T. B., Nielsen, H. M., Lindahl, L., Fredholm, S., Kongsbak-Wismann, Martin, Willerslev-Olsen, A., Buus, Terkild Brink, Nastasi, C., Hu, T., Gluud, Maria, Côme, Christophe Roger Michel, Krejsgaard, T., Iversen, L., Bonefeld, Charlotte Menne, Grønbæk, Kirsten, Met, Özcan, Woetmann, Anders , Ødum, Niels & Geisler, Carsten, 2021, In: Dermatology. 237, 2, p. 283-290 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The ectopic expression of meiCT genes promotes meiomitosis and may facilitate carcinogenesis
Gantchev, J., Villarreal, A., Gunn, S., Zetka, M., Ødum, Niels & Litvinov, I. V., 2020, In: Cell Cycle. 19, 8, p. 837-854Research output: Contribution to journal › Review › Research › peer-review
- Published
The effect of short-chain fatty acids on human monocyte-derived dendritic cells
Nastasi, C., Candela, M., Bonefeld, Charlotte Menne, Geisler, Carsten, Hansen, M., Krejsgaard, T., Biagi, E., Andersen, Mads Hald, Brigidi, P., Ødum, Niels, Litman, T. & Woetmann, Anders , 2015, In: Scientific Reports. 5, 10 p., 16148.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The functional interlink between AR and MMP9/VEGF signaling axis is mediated through PIP5K1α/pAKT in prostate cancer
Larsson, P., Syed Khaja, A. S., Semenas, J., Wang, T., Sarwar, M., Dizeyi, N., Simoulis, A., Hedblom, A., Wai, S. N., Ødum, Niels & Persson, J. L., 2020, In: International Journal of Cancer. 146, 6, p. 1686-1699Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The immune privilege of the eye: human retinal pigment epithelial cells selectively modulate T-cell activation in vitro.
Kaestel, C. G., Lovato, P., Ødum, Niels, Nissen, Mogens Holst & Röpke, C., 2005, In: Current Eye Research. 30, 5, p. 375-83 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The immunodeficiency of bone marrow-transplanted patients. II. CD8-related suppression by patient lymphocytes of the response of donor lymphocytes to mitogens, antigens, and allogeneic cells
Ødum, Niels, Hofmann, B., Jacobsen, N., Langhoff, E., Møller, J., Platz, P., Ryder, L. P. & Svejgaard, A., 1987, In: Scandinavian Journal of Immunology. 26, 3, p. 247-53 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The inhibitory checkpoint, PD-L2, is a target for effector T cells: Novel possibilities for immune therapy
Ahmad, S. M., Martinenaite, E., Holmström, M., Jørgensen, M. A., Met, Özcan, Nastasi, C., Klausen, U., dqp123, dqp123, Pedersen, Lars Møller, Munksgaard, Lars, Ødum, Niels, Woetmann, Anders , Svane, Inge Marie & Andersen, Mads Hald, 2018, In: OncoImmunology. 7, 2, 10 p., e1390641.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The junctional adhesion molecule-like protein (JAML) is important for the inflammatory response during contact hypersensitivity
Mraz, Veronika, Lohmann, R. K. D., Menzel, Mandy, Hawkes, A., Vaher, Helen, Funch, Anders Boutrup, Jee, Mia Hamilton, Gadsbøll, A. S. Ø., Weber, Julie Friis, Yeung, Kelvin, Ødum, Niels, Woetmann, Anders , McKay, D., Witherden, D., Geisler, Carsten & Bonefeld, Charlotte Menne, 2023, In: Contact Dermatitis. 89, 5, p. e63-e65Research output: Contribution to journal › Journal article › Research › peer-review
ID: 14062
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Vitamin D up-regulates the vitamin D receptor by protecting it from proteasomal degradation in human CD4+ T cells
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Vitamin D counteracts Mycobacterium tuberculosis-induced cathelicidin downregulation in dendritic cells and allows Th1 differentiation and IFNγ secretion
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STAT5 induces miR-21 expression in cutaneous T cell lymphoma
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Published