Niels Ødum
Professor
Skin Immunology Research Center
Blegdamsvej 3B, 2200 København N, 07 Bygning 7, Building: 07-12-86
Member of:
- Published
Inhibition of T cell proliferation by selective block of Ca(2+)-activated K(+) channels
Jensen, B. S., Ødum, Niels, Jorgensen, N. K., Christophersen, P. & Olesen, Søren-Peter, 1999, In: Proceedings of the National Academy of Science of the United States of America. 96, 19, p. 10917-21 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Inhibition of T cell proliferation by selective block of Ca2+-activated K+ channels
Jensen, B. S., Ødum, Niels, Jørgensen, N. K., Christophersen, P. & Olesen, Søren-Peter, 1999, In: Proceedings of the National Academy of Science of the United States of America. 96, p. 10917-10921Research output: Contribution to journal › Journal article › Research › peer-review
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Inhibition of allostimulated HLA-DQ and DP-specific T cells by staphylococcal enterotoxin A
Masewicz, S., Ledbetter, J. A., Martin, P., Mickelson, E., Hansen, J. A. & Ødum, Niels, 1993, In: Human Immunology. 36, 3, p. 142-8 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Inhibition of human lymphocyte proliferation and cleavage of interleukin-2 by Pseudomonas aeruginosa proteases
Theander, Thor Grundtvig, Kharazmi, A., Pedersen, Bente Klarlund, Christensen, L. D., Tvede, N., Poulsen, Lars K., Ødum, Niels, Svenson, M. & Bendtzen, K., 1988, In: Infection and Immunity. 56, 7, p. 1673-7 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Inhibition of succinate dehydrogenase activity impairs human T cell activation and function: [Publisher correction]
Nastasi, C., Willerlev-Olsen, A., Dalhoff, K., Ford, Shayne Lavondua, Gadsbøll, A. S. Ø., Buus, Terkild Brink, Gluud, Maria, Danielsen, M., Litman, Thomas, Bonefeld, Charlotte Menne, Geisler, Carsten, Ødum, Niels & Woetmann, Anders , 2021, In: Scientific Reports. 11, 1, 1458.Research output: Contribution to journal › Journal article › Research › peer-review
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Interferon-alpha induces transient suppressors of cytokine signalling expression in human T cells
Brender, C., Nielsen, M., Röpke, C., Nissen, M. H., Svejgaard, A., Billestrup, N., Geisler, Carsten & Ødum, Niels, 2001, In: Experimental and Clinical Immunogenetics. 18, 2, p. 80-5 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Interleukin 1-induced down-regulation of antibody binding to CD4 molecules on human lymphocytes
Tvede, N., Christensen, L. D., Ødum, Niels, Wiik, A. & Bendtzen, K., 1988, In: Scandinavian Journal of Immunology. 27, 6, p. 679-84 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Interleukin 2 and 15 activate Stat3alpha in human T lymphocytes
Nielsen, M., Svendsen, Mette Nordahl, Svejgaard, A. & Ødum, Niels, 1998, In: Cytokine. 10, 10, p. 735-8 3 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Interleukin 21 therapy increases the density of tumor infiltrating CD8+ T cells and inhibits the growth of syngeneic tumors
Søndergaard, H., Frederiksen, K. S., Thygesen, P., Galsgaard, E. D., Skak, K., Kristjansen, P. E. G., Ødum, Niels & Kragh, M., 2007, In: Cancer Immunology, Immunotherapy. 56, 9, p. 1417-28 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Interleukin-2 and -15 activate Stat 3a in human T lymphocytes
Nielsen, M., Pedersen, M. N., Svejgaard, A. & Ødum, Niels, 1998, In: Cytokine. 10, p. 735-738Research output: Contribution to journal › Journal article › Research
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Interleukin-2 induces tyrosine phosphorylation and nuclear translocation of stat3 in human T lymphocytes
Nielsen, M., Svejgaard, A., Skov, S. & Ødum, Niels, 1994, In: European Journal of Immunology. 24, 12, p. 3082-6 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Interleukin-26 (IL-26) is a novel anti-microbial peptide produced by T cells in response to staphylococcal enterotoxin
Woetmann, Anders , Alhede, M., Dabelsteen, Sally, Bjarnsholt, Thomas, Rybtke, Morten Levin, Nastasi, C., Krejsgaard, T., Andersen, Mads Hald, Bonefeld, Charlotte Menne, Geisler, Carsten, Givskov, Michael & Ødum, Niels, 2018, In: OncoTarget. 9, 28, p. 19481-19489 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Interleukine-2 induces tyrosine phosphorylation and nuclear translocation of stat3 in human T lymphocytes
Nielsen, M., Svejgaard, A., Skov, S. & Ødum, Niels, 1994, In: European Journal of Immunology. 12, p. 3082Research output: Contribution to journal › Journal article › Research
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Intratumoral interleukin-21 increases antitumor immunity, tumor-infiltrating CD8+ T-cell density and activity, and enlarges draining lymph nodes
Søndergaard, H., Galsgaard, E. D., Bartholomaeussen, M., Straten, P. T., Ødum, Niels & Skak, K., 2010, In: Journal of Immunotherapy. 33, 3, p. 236-49 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Investigating heredity in cutaneous T-cell lymphoma in a unique cohort of Danish twins
Ødum, Niels, Lindahl, L. M., Wod, M., Krejsgaard, T. F., Skytthe, A., Woetmann, Anders , Iversen, L. & Christensen, K., Jan 2017, In: Blood Cancer Journal. 7, 1, 3 p., e518.Research output: Contribution to journal › Comment/debate › Research › peer-review
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Investigating potential exogenous tumor initiating and promoting factors for Cutaneous T-Cell Lymphomas (CTCL), a rare skin malignancy
Litvinov, I. V., Shtreis, A., Kobayashi, K., Glassman, S., Tsang, M., Woetmann, Anders , Sasseville, D., Ødum, Niels & Duvic, M., 2 Jul 2016, In: OncoImmunology. 5, 7, 5 p., e1175799.Research output: Contribution to journal › Review › Research › peer-review
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Investigation of immunosuppressive properties of inactivated human immunodeficiency virus and possible neutralization of this effect by some patient sera
Hofmann, B., Langhoff, E., Lindhardt, B. O., Ødum, Niels, Hyldig-Nielsen, J. J., Ryder, L. P., Platz, P., Jakobsen, B. K., Bendtzen, K. & Jacobsen, N., 1989, In: Cellular Immunology. 121, 2, p. 336-48 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
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JAK3 Is Expressed in the Nucleus of Malignant T Cells in Cutaneous T Cell Lymphoma (CTCL)
Vadivel, Chella Krishna, Gluud, Maria, Torres-rusillo, S., Boding, L., Willerslev-olsen, A., Buus, Terkild Brink, Nielsen, T. K., Persson, J. L., Bonefeld, Charlotte Menne, Geisler, Carsten, Krejsgaard, T., Fuglsang, Anja Thoe, Ødum, Niels & Woetmann, Anders , 2021, In: Cancers. 13, 2, 280.Research output: Contribution to journal › Journal article › Research › peer-review
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JNK1, but not JNK2, is required in two mechanistically distinct models of inflammatory arthritis
Denninger, K., Rasmussen, S. B., Larsen, J. M., Ørskov, Cathrine, Poulsen, Steen Seier, Sørensen, P., Christensen, Jan Pravsgaard, Illges, H., Ødum, Niels & Labuda, T., 2011, In: American Journal of Pathology. 179, 4, p. 1884-93 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Jak3, STAT3, and STAT5 inhibit expression of miR-22, a novel tumor suppressor microRNA, in cutaneous T-Cell lymphoma
Sibbesen, N. A., Kopp, K. L., Litvinov, I. V., Jønson, L., Willerslev-Olsen, A., Fredholm, S., Petersen, D. L., Nastasi, C., Krejsgaard, T., Lindahl, L. M., Gniadecki, R., Mongan, N. P., Sasseville, D., Wasik, M. A., Iversen, L., Bonefeld, Charlotte Menne, Geisler, Carsten, Woetmann, Anders & Ødum, Niels, 2015, In: OncoTarget. 6, 24, p. 20555-69 15 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Jak3- and JNK-dependent vascular endothelial growth factor expression in cutaneous T-cell lymphoma
Krejsgaard, T., Vetter-Kauczok, C. S., Woetmann, Anders , Lovato, P., Labuda, T., Eriksen, K. W., Zhang, Q., Becker, J. C. & Ødum, Niels, 2006, In: Leukemia. 20, 10, p. 1759-66 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Kinetic analysis of interleukin 2 (IL-2) production and expression of IL-2 receptors by uraemic and normal lymphocytes
Langhoff, E., Hofmann, B., Ødum, Niels, Ladefoged, J., Platz, P., Ryder, L. P., Svejgaard, A. & Ødum, Niels, 1987, In: Scandinavian Journal of Immunology. 25, 1, p. 29-36 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Lack of Phosphotyrosine Phosphatase SHP-1 Expression in Malignant T-Cell Lymphoma Cells Results from Methylation of the SHP-1 Promoter
Zhang, Q., Raghunath, P. N., Vonderheid, E., Ødum, Niels & Wasik, M. A., 2000, In: American Journal of Pathology. 157, 4, p. 1137-46 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Lack of phosphotyrosine phosphatase SHP-1 expression in malignant T cell lymphoma cells results from methylation of the SHP-1 promotor
Zhang, Q., Raghunath, P. N., Vonderheid, E., Ødum, Niels & Wasik, M. A., 2000, In: American Journal of Pathology. 157, p. 1137-1146Research output: Contribution to journal › Journal article › Research › peer-review
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Leucine-based receptor sorting motifs are dependent on the spacing relative to the plasma membrane
Geisler, Carsten, Dietrich, J., Nielsen, B. L., Kastrup, J., Lauritsen, J. P. H., Ødum, Niels & Bartels, Mette Damkjær, 1998, In: Journal of Biological Chemistry. 273, 33, p. 21316-23 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Lifestyle and demographic associations with 47 inflammatory and vascular stress biomarkers in 9876 blood donors
Kjerulff, B., Dowsett, J., Jacobsen, R. L., Gladov, J., Larsen, M. H., Lundgaard, A. T., Banasik, K., Westergaard, D., Mikkelsen, S., Dinh, K. M., Hindhede, L., Kaspersen, K. A., Schwinn, M., Juul, A., Poulsen, B., Lindegaard, B., Pedersen, C. B., Sabel, C. E., Bundgaard, H., Nielsen, H. S. & 30 others, , 2024, In: Communications Medicine. 4, 15 p., 50.Research output: Contribution to journal › Journal article › Research › peer-review
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Ligand-induced TCR down-regulation is not dependent on constitutive TCR cycling
Dietrich, J., Bonefeld, Charlotte Menne, Lauritsen, J. P. H., von Essen, Marina Rode, Rasmussen, B. A., Ødum, Niels & Geisler, Carsten, 2002, In: Journal of Immunology. 168, 11, p. 5434-40 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Loss of SHP-1 tyrosine phosphatase expression correlates with the advanced stages of cutaneous T-cell lymphoma
Witkiewicz, A., Raghunath, P., Wasik, A., Junkins-Hopkins, J. M., Jones, D., Zhang, Q., Ødum, Niels & Wasik, M. A., 2007, In: Human Pathology. 38, 3, p. 462-7 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Low SATB1 Expression Promotes IL-5 and IL-9 Expression in Sézary Syndrome
Herrera, A., Fredholm, S., Cheng, A., Mimitou, E. P., Seffens, A., Bar-Natan, M., Sun, A., Latkowski, J. A., Willerslew-Olsen, A., Buus, T. B., Gluud, M., Krejsgaard, T., Torres-Rusillo, S., Bonefeld, C. M., Woetmann, A., Geisler, C., Geskin, L. J., Ouyang, Z., Smibert, P., Ødum, N. & 1 others, , 2020, In: Journal of Investigative Dermatology. 140, 3, p. 713-716 4 p.Research output: Contribution to journal › Letter › Research › peer-review
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Low prevalence of antibodies and other factors binding to CC-chemokines and IL-2 in HIV-positive patients
Meyer, C. N., Svenson, M., Larsen, C. S., Ødum, Niels, Skinhøj, P. & Bendzen, K., 2000, In: APMIS : Acta pathologica, microbiologica et immunologica Scandinavica. Supplementum. 108, p. 122-130Research output: Contribution to journal › Journal article › Research › peer-review
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Low prevalence of antibodies and other plasma factors binding to CC chemokines and IL-2 in HIV-positive patients
Meyer, C. N., Svenson, M., Schade Larsen, C., Ødum, Niels, Skinhøj, P. & Bendtzen, K., 2000, In: Acta Pathologica Microbiologica et Immunologica Scandinavica. 108, 2, p. 122-30 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Lymphocyte transformation response to pokeweed mitogen as a predictive marker for development of AIDS and AIDS related symptoms in homosexual men with HIV antibodies
Hofmann, B., Lindhardt, B. O., Gerstoft, J., Petersen, C. S., Platz, P., Ryder, L. P., Ødum, Niels, Dickmeiss, E., Nielsen, P. B. & Ullman, S., 1987, In: British medical journal (Clinical research ed.). 295, 6593, p. 293-6 3 p.Research output: Contribution to journal › Journal article › Research › peer-review
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MHC class I ligation of human T cells activates the TYK-2 kinase and induces tyrosine phosphorylation, nuclear translocation, and DNA binding of the Stat3 transcription factor
Skov, Søren, Nielsen, M., Bregenholt, S., Ødum, Niels & Claesson, Mogens Helweg, 1998, In: Blood. 91, p. 3566-3573Research output: Contribution to journal › Journal article › Research › peer-review
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MHC class I signaling in T cells leads to tyrosine kinase activity and PLC-gamma 1 phosphorylation
Skov, S., Ødum, Niels & Claesson, Mogens Helweg, 1995, In: Journal of Immunology. 154, 3, p. 1167-76 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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MHC class II molecules deliver costimulatory signals in human T cells through a functional linkage with IL-2-receptors
Ødum, Niels, Kanner, S. B., Ledbetter, J. A. & Svejgaard, A., 1993, In: Journal of Immunology. 150, 12, p. 5289-98 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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MHC class II molecules regulate growth in human T cells
Nielsen, M., Ødum, Niels, Bendtzen, K., Ryder, L. P., Jakobsen, B. K. & Svejgaard, A., 1994, In: Experimental and Clinical Immunogenetics. 11, 1, p. 23-32 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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MICRORNA 203 CONTROLS T-CELL LYMPHOMAGENESIS BY TARGETING IL-2 RECEPTOR SIGNALING
Ralfkiaer, U., Jansson, Martin David, Kopp, K., Willerslev-Olsen, A., Asmar, F., Krejsgaard, T., Brown, P., Gniadecki, R., Woetmann, Anders , Lund, Anders H., Ødum, Niels & Grønbæk, Kirsten, 22 Jun 2015, In: Haematologica. 100, supplement 1, p. 104-105 2 p., P317.Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
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MID2 can substitute for MID1 and control exocytosis of lytic granules in cytotoxic T cells
Boding, L., Hansen, A. K., Meroni, G., Levring, T. B., Woetmann, Anders , Ødum, Niels, Bonefeld, Charlotte Menne & Geisler, Carsten, Aug 2015, In: APMIS : acta pathologica, microbiologica, et immunologica Scandinavica. 123, 8, p. 682-7 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Macrophages Control the Bioavailability of Vitamin D and Vitamin D-Regulated T Cell Responses
Lopez, D. V., Al-Jaberi, F. A. H., Woetmann, Anders , Ødum, Niels, Bonefeld, Charlotte Menne, Kongsbak-Wismann, Martin & Geisler, Carsten, 2021, In: Frontiers in Immunology. 12, 722806.Research output: Contribution to journal › Journal article › Research › peer-review
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Malignant T Cells Secrete Galectins and Induce Epidermal Hyperproliferation and Disorganized Stratification in a Skin Model of Cutaneous T Cell Lymphoma
Thode, C., Woetmann, Anders , Wandall, Hans H., Carlsson, M. C., Qvortrup, Klaus, Kauczok, C., Wobser, M., Printzlau, A., Ødum, Niels & Dabelsteen, Sally, Jan 2015, In: Journal of Investigative Dermatology. 135, 1, p. 238-246 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Malignant T cells activate endothelial cells via IL-17F
Lauenborg, B. T., Litvinov, I. V., Zhou, Y., Willerslev-Olsen, A., Bonefeld, Charlotte Menne, Nastasi, C., Fredholm, S., Lindahl, L. M., Sasseville, D., Geisler, Carsten, Wasik, M., Krejsgaard, T., Gjerdrum, Lise Mette Rahbek, Iversen, L., Ødum, Niels & Woetmann, Anders , 2017, In: Blood Cancer Journal. 7, 3 p., e586.Research output: Contribution to journal › Comment/debate › Research
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Malignant T cells exhibit CD45 resistant Stat 3 activation and proliferation in cutaneous T cell lymphoma.
Krejsgaard, T., Helvad, R., Ralfkiær, E., Astvad, K., Grønbæk, K., Eriksen, K., Geisler, C., Kopp, K. L. M., Zhang, Q., Ødum, Niels, Woetmann, Anders , Katharina, K., Wasik, M., Odum, N. & Woetmann, A., 2010, In: The Open Leukemia Journal. 3, p. 9-15Research output: Contribution to journal › Journal article › Research › peer-review
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Malignant T cells exhibit CD45 resistant Stat3 activation and proliferation in cutaneous
Krejsgaard, T. F., Helvad, R., Ralfkiaer, E., Astvad, K., Grønbæk, K., Eriksen, K. W., Geisler, C., Kopp, K. L. M., Zhang, Q., Ødum, Niels & Woetmann, Anders , 2010, In: The Open Leukemia Journal. 3, p. 9-15Research output: Contribution to journal › Journal article › Research › peer-review
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Malignant T cells express lymphotoxin alpha and drive endothelial activation in cutaneous T cell lymphoma
Lauenborg, B., Christensen, L., Ralfkiaer, U., Kopp, K. L. M., Jønson, L., Dabelsteen, Sally, Bonefeld, Charlotte Menne, Geisler, Carsten, Gjerdrum, Lise Mette Rahbek, Zhang, Q., Wasik, M. A., Ralfkiaer, E., Ødum, Niels & Woetmann, Anders , 2015, In: OncoTarget. 6, 17, p. 15235-15249 15 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Malignant T cells induce skin barrier defects through cytokine-mediated JAK/STAT signaling in cutaneous T-cell lymphoma
Gluud, M., Pallesen, E. M. H., Buus, T. B., Gjerdrum, L. M. R., Lindahl, L. M., Kamstrup, M. R., Bzorek, M., Danielsen, M., Bech, R., Monteiro, M. N., Blümel, E., Willerslev-Olsen, A., Lykkebo-Valløe, A., Vadivel, C. K., Krejsgaard, T., Bonefeld, C. M., Geisler, C., Becker, J. C., Koralov, S. B., Iversen, L. & 3 others, , 2023, In: Blood. 141, 2, p. 180-193 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Malignant Tregs express low molecular splice forms of FOXP3 in Sézary syndrome
Krejsgaard, T., Gjerdrum, L. M., Ralfkiaer, E., Lauenborg, B., Eriksen, K. W., Mathiesen, A., Bovin, L. F., Gniadecki, R., Geisler, Carsten, Ryder, L. P., Zhang, Q., Wasik, M. A., Ødum, Niels & Woetmann, Anders , 2008, In: Leukemia. p. 2230-2239 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Malignant cutaneous T-cell lymphoma cells express IL-17 utilizing the Jak3/Stat3 signaling pathway
Krejsgaard, T. F., Ralfkiær, U., Clasen-Linde, E., Eriksen, K. W. K., Kopp, K. L. M., Bonefeld, Charlotte Menne, Geisler, Carsten, Dabelsteen, Sally, Wasik, M. A., Ralfkiaer, E. M., Woetmann, Anders & Ødum, Niels, 2011, In: Journal of Investigative Dermatology. 131, 6, p. 1331-1338 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Malignant inflammation in cutaneous T-cell lymphoma—a hostile takeover
Krejsgaard, T., Lindahl, L. M., Mongan, N. P., Wasik, M. A., Litvinov, I. V., Iversen, L., Langhoff, E., Woetmann, Anders & Ødum, Niels, 2017, In: Seminars in Immunopathology. 39, 3, p. 269–282 14 p.Research output: Contribution to journal › Review › Research › peer-review
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Malignant transformation of CD4+ T lymphocytes mediated by oncogenic kinase NPM/ALK recapitulates IL-2-induced cell signaling and gene expression reprogramming
Marzec, Michal Tomasz, Halasa, K., Liu, X., Wang, H. Y., Cheng, M., Baldwin, D., Tobias, J. W., Schuster, S. J., Woetmann, Anders , Zhang, Q., Turner, S. D., Ødum, Niels & Wasik, M. A., 15 Dec 2013, In: Journal of immunology (Baltimore, Md. : 1950). 191, 12, p. 6200-7 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Masking of the CD3 gamma di-leucine-based motif by zeta is required for efficient T-cell receptor expression
Lauritsen, J. P. H., Bonefeld, Charlotte Menne, von Essen, Marina Rode, Nielsen, M. W., Rasmussen, A. B., Ødum, Niels, Dietrich, J. & Geisler, Carsten, 2004, In: Traffic - International Journal of Intracellular Transport. 5, 9, p. 672-84 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
ID: 14062
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Vitamin D up-regulates the vitamin D receptor by protecting it from proteasomal degradation in human CD4+ T cells
Research output: Contribution to journal › Journal article › Research › peer-review
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427
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Vitamin D counteracts Mycobacterium tuberculosis-induced cathelicidin downregulation in dendritic cells and allows Th1 differentiation and IFNγ secretion
Research output: Contribution to journal › Journal article › Research › peer-review
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351
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STAT5 induces miR-21 expression in cutaneous T cell lymphoma
Research output: Contribution to journal › Journal article › Research › peer-review
Published