Niels Ødum
Professor
Skin Immunology Research Center
Blegdamsvej 3B, 2200 København N, 07 Bygning 7, Building: 07-12-86
Member of:
- Published
Investigating potential exogenous tumor initiating and promoting factors for Cutaneous T-Cell Lymphomas (CTCL), a rare skin malignancy
Litvinov, I. V., Shtreis, A., Kobayashi, K., Glassman, S., Tsang, M., Woetmann, Anders , Sasseville, D., Ødum, Niels & Duvic, M., 2 Jul 2016, In: OncoImmunology. 5, 7, 5 p., e1175799.Research output: Contribution to journal › Review › Research › peer-review
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Vitamin D Inhibits IL-22 Production Through a Repressive Vitamin D Response Element in the il22 Promoter
Lopez, D. V., Al-Jaberi, F. A. H., Damas, N. D., Weinert, B. T., Pus, U., Torres-Rusillo, S., Woetmann, Anders , Ødum, Niels, Bonefeld, Charlotte Menne, Kongsbak-Wismann, Martin & Geisler, Carsten, 2021, In: Frontiers in Immunology. 12, 715059.Research output: Contribution to journal › Journal article › Research › peer-review
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Macrophages Control the Bioavailability of Vitamin D and Vitamin D-Regulated T Cell Responses
Lopez, D. V., Al-Jaberi, F. A. H., Woetmann, Anders , Ødum, Niels, Bonefeld, Charlotte Menne, Kongsbak-Wismann, Martin & Geisler, Carsten, 2021, In: Frontiers in Immunology. 12, 722806.Research output: Contribution to journal › Journal article › Research › peer-review
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Constitutive STAT3 activation in intestinal T cells from patients with Crohn's disease
Lovato, P., Brender, C., Agnholt, J., Kelsen, J., Kaltoft, K., Svejgaard, A., Eriksen, K. W., Woetmann, Anders & Ødum, Niels, 2003, In: Journal of Biological Chemistry. 278, 19, p. 16777-81 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
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SHP2 regulates IL-2 induced MAPK activation, but not Stat3 or Stat5 tyrosine phosphorylation, in cutaneous T cell lymphoma cells
Lundin Brockdorff, J., Woetmann, Anders , Mustelin, T., Kaltoft, K., Zhang, Q., Wasik, M. A., Röpke, C. & Ødum, Niels, 2002, In: Cytokine. 20, 4, p. 141-7 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
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IL-15 induces unspecific effector functions in human peptide-specific CD8+ T-cell cultures.
Lyngstrand, S. T., Würtzen, P. A., Ødum, Niels, Nissen, Mogens Holst & Röpke, C., 2002, In: Scandinavian Journal of Immunology. 56, 6, p. 602-10 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Comparison of microRNA expression using different preservation methods of matched psoriatic skin samples
Løvendorf, M. B., Zibert, J. R., Hagedorn, P. H., Glue, C., Ødum, Niels, Røpke, M. A. & Skov, L., 2012, In: Experimental Dermatology. 21, 4, p. 299-301 3 p.Research output: Contribution to journal › Journal article › Research › peer-review
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New DPB1 alleles
Madsen, H. O., Ryder, L. P., Fugger, L., Ødum, Niels, Jakobsen, B. K. & Svejgaard, A., 1992, In: HLA. 39, 2, p. 102-3 1 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Imbalanced IL-1B and IL-18 Expression in Sézary Syndrome
Manfrere, K. C. G., Torrealba, M. P., Ferreira, F. M., de Sousa, E. S. A., Miyashiro, D., Teixeira, F. M. E., Custódio, R. W. A., Nakaya, H. I., Ramos, Y. A. L., Sotto, M. N., Woetmann, Anders , Ødum, Niels, Duarte, A. J. D. S., Sanches, J. A. & Sato, M. N., 2023, In: International Journal of Molecular Sciences. 24, 5, 4674.Research output: Contribution to journal › Journal article › Research › peer-review
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miR-122 regulates p53/Akt signalling and the chemotherapy-induced apoptosis in cutaneous T-cell lymphoma
Manfè, V., Biskup, E., Rosbjerg, A., Kamstrup, M., Skov, A. G., Lerche, C. M., Lauenborg, B. T., Ødum, Niels & Gniadecki, R., Jan 2012, In: PLOS ONE. 7, 1, e29541.Research output: Contribution to journal › Journal article › Research › peer-review
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cMyc/miR-125b-5p signalling determines sensitivity to bortezomib in preclinical model of cutaneous T-cell lymphomas
Manfè, V., Biskup, E., Willumsgaard, A., Skov, A. G., Palmieri, D., Gasparini, P., Laganá, A., Woetmann, Anders , Ødum, Niels, Croce, C. M. & Gniadecki, R., 2013, In: PloS one. 8, 3, p. e59390Research output: Contribution to journal › Journal article › Research › peer-review
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Validation of a diagnostic miRNA classifier in cutaneous T-cell lymphomas
Marstrand, T., Ahler, C. B., Ralfkiaer, U., Clemmensen, A., Kopp, K. L., Sibbesen, N. A., Krejsgaard, T., Litman, Thomas, Wasik, M. A., Bonefeld, Charlotte Menne, Grønbæk, Kirsten, Gjerdum, L. M. R., Gniadecki, R., Ralfkiaer, E., Geisler, Carsten, Woetmann, Anders , Røpke, M. A., Glue, C., Skov, Lone & Ødum, Niels, 2014, In: Leukemia and Lymphoma. 55, 4, p. 957-958 2 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Citrullination of myelin basic protein induces a Th17-cell response in healthy individuals and enhances the presentation of MBP85-99 in patients with multiple sclerosis
Martín Monreal, M. T., Hansen, B. E., Iversen, P. F., Enevold, Christian, Ødum, Niels, Sellebjerg, Finn Thorup, Højrup, P., von Essen, Marina Rode & Nielsen, Claus Henrik, 2023, In: Journal of Autoimmunity. 139, 103092.Research output: Contribution to journal › Journal article › Research › peer-review
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Applicability of Small-Molecule Inhibitors in the Study of Peptidyl Arginine Deiminase 2 (PAD2) and PAD4
Martín Monreal, M. T., Stripp, Alexandra, Massarenti, Laura, Mondal, S., Šenolt, L., Ødum, Niels, Nielsen, Michael Lund, Thompson, P. R., Nielsen, Claus Henrik & Damgaard, D., 2021, In: Frontiers in Immunology. 12, 11 p., 716250.Research output: Contribution to journal › Journal article › Research › peer-review
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Differential Effects of Interleukin-2 and Interleukin-15 versus Interleukin-21 on CD4+ Cutaneous T-Cell Lymphoma Cells
Marzec, Michal Tomasz, Halasa, K., Kasprzycka, M., Wysocka, M., Liu, X., Tobias, J. W., Baldwin, D., Zhang, Q., Ødum, Niels, Rook, A. H. & Wasik, M. A., 2008, In: Cancer Research. 68, 4, p. 1083-91 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Malignant transformation of CD4+ T lymphocytes mediated by oncogenic kinase NPM/ALK recapitulates IL-2-induced cell signaling and gene expression reprogramming
Marzec, Michal Tomasz, Halasa, K., Liu, X., Wang, H. Y., Cheng, M., Baldwin, D., Tobias, J. W., Schuster, S. J., Woetmann, Anders , Zhang, Q., Turner, S. D., Ødum, Niels & Wasik, M. A., 15 Dec 2013, In: Journal of immunology (Baltimore, Md. : 1950). 191, 12, p. 6200-7 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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IL-2- and IL-15-induced activation of the rapamycin-sensitive mTORC1 pathway in malignant CD4+ T lymphocytes
Marzec, Michal Tomasz, Liu, X., Kasprzycka, M., Witkiewicz, A., Raghunath, P. N., El-Salem, M., Robertson, E., Ødum, Niels & Wasik, M. A., 2008, In: Blood. 111, 4, p. 2181-9 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Inhibition of ALK enzymatic activity in T-cell lymphoma cells induces apoptosis and suppresses proliferation and STAT3 phosphorylation independently of Jak3
Marzec, Michal Tomasz, Kasprzycka, M., Ptasznik, A., Wlodarski, P., Zhang, Q., Ødum, Niels & Wasik, M. A., 2005, In: Laboratory Investigation. 85, 12, p. 1544-54 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Oncogenic kinase NPM/ALK induces expression of HIF1 alpha mRNA
Marzec, Michal Tomasz, Liu, X., Wong, W., Yang, Y., Pasha, T., Kantekure, K., Zhang, P., Woetmann, Anders , Cheng, M., Ødum, Niels & Wasik, M. A., 2011, In: Oncogene. 30, 11, p. 1372-1378 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Simultaneous inhibition of mTOR-containing complex 1 (mTORC1) and MNK induces apoptosis of cutaneous T-cell lymphoma (CTCL) cells
Marzec, Michal Tomasz, Liu, X., Wysocka, M., Rook, A. H., Ødum, Niels & Wasik, M. A., 16 Sep 2011, In: PLoS ONE. 6, 9, 8 p., e24849.Research output: Contribution to journal › Journal article › Research › peer-review
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Inhibition of allostimulated HLA-DQ and DP-specific T cells by staphylococcal enterotoxin A
Masewicz, S., Ledbetter, J. A., Martin, P., Mickelson, E., Hansen, J. A. & Ødum, Niels, 1993, In: Human Immunology. 36, 3, p. 142-8 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Peptidylarginine deiminase-4 gene polymorphisms are associated with systemic lupus erythematosus and lupus nephritis
Massarenti, Laura, Enevold, C., Damgaard, D., Ødum, Niels, Nielsen, Claus Henrik & Jacobsen, Søren, 2019, In: Scandinavian Journal of Rheumatology. 48, 2, p. 133-140Research output: Contribution to journal › Journal article › Research › peer-review
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Peptidylarginine Deiminase 2 Gene Polymorphisms in Subjects with Periodontitis Predispose to Rheumatoid Arthritis
Massarenti, Laura, Enevold, C., Damgaard, D., Hansen, Peter Riis, Frisch, M., Ødum, Niels, Jacobsen, Søren & Nielsen, Claus Henrik, 2022, In: International Journal of Molecular Sciences. 23, 17, 10 p., 9536.Research output: Contribution to journal › Journal article › Research › peer-review
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PADI4 Polymorphisms Confer Risk of Anti-CCP-Positive Rheumatoid Arthritis in Synergy With HLA-DRB1*04 and Smoking
Massarenti, Laura, Enevold, C., Damgaard, D., Ødum, Niels, Garred, Peter, Frisch, M., Shelef, M. A., Jacobsen, Søren & Nielsen, Claus Henrik, 2021, In: Frontiers in Immunology. 12, 707690.Research output: Contribution to journal › Journal article › Research › peer-review
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Bacterial genotoxins induce T cell senescence
Mathiasen, S. L., Gall Mas, Laura, Pateras, I. S., Theodorou, S. D. P., Namini, Martin Rich Javadi, Hansen, Morten Bagge, Martin, O. C. B., Vadivel, Chella Krishna, Ntostoglou, K., Butter, D., Givskov, Michael, Geisler, Carsten, Akbar, A. N., Gorgoulis, V. G., Frisan, T., Ødum, Niels & Krejsgaard, T., 2021, In: Cell Reports. 35, 10, 109220.Research output: Contribution to journal › Journal article › Research › peer-review
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Ceramide-induced TCR up-regulation
Bonefeld, Charlotte Menne, Lauritsen, J. P. H., Dietrich, J., Kastrup, J., Wegener, A. M., Ødum, Niels & Geisler, Carsten, 2000, In: Journal of Immunology. 165, 6, p. 3065-72 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Endo- and exocytic rate constants for spontaneous and protein kinase C-activated T cell receptor cycling
Bonefeld, Charlotte Menne, Møller Sørensen, T., Siersma, Volkert Dirk, von Essen, Marina Rode, Ødum, Niels & Geisler, Carsten, 2002, In: European Journal of Immunology. 32, 3, p. 616-26 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Androgen dependent mechanisms of pro-angiogenic networks in placental and tumor development
Metzler, V. M., de Brot, S., Robinson, R. S., Jeyapalan, J. N., Rakha, E., Walton, T., Gardner, D. S., Lund, E. F., Whitchurch, J., Haigh, D., Lochray, J. M., Robinson, B. D., Allegrucci, C., Fray, R. G., Persson, J. L., Ødum, N., Miftakhova, R. R., Rizvanov, A. A., Hughes, I. A., Tadokoro-Cuccaro, R. & 3 others, , 2017, In: Placenta. 56, p. 79-85Research output: Contribution to journal › Journal article › Research › peer-review
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Low prevalence of antibodies and other plasma factors binding to CC chemokines and IL-2 in HIV-positive patients
Meyer, C. N., Svenson, M., Schade Larsen, C., Ødum, Niels, Skinhøj, P. & Bendtzen, K., 2000, In: Acta Pathologica Microbiologica et Immunologica Scandinavica. 108, 2, p. 122-30 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Low prevalence of antibodies and other factors binding to CC-chemokines and IL-2 in HIV-positive patients
Meyer, C. N., Svenson, M., Larsen, C. S., Ødum, Niels, Skinhøj, P. & Bendzen, K., 2000, In: APMIS : Acta pathologica, microbiologica et immunologica Scandinavica. Supplementum. 108, p. 122-130Research output: Contribution to journal › Journal article › Research › peer-review
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Proinflammatory biomarkers are associated with prediabetes in patients with schizophrenia
Mller, M., Fredholm, S., Jensen, M. E., Wörtwein, Gitta, Larsen, J. R., Vilsbøll, Tina, Ødum, Niels & Fink-Jensen, Anders, 2022, In: CNS Spectrums. 27, 3, 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Characterization of circulating extracellular traps and immune responses to citrullinated LL37 in psoriasis
Monreal, M. T. M., Kvist-Hansen, A., Massarenti, Laura, Steffensen, R., Loft, N., Hansen, Peter Riis, Ødum, Niels, Skov, Lone & Nielsen, Claus Henrik, 2023, In: Frontiers in Immunology. 14, 10 p., 1247592.Research output: Contribution to journal › Journal article › Research › peer-review
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DNA polymorphism of HLA class II genes in alopecia areata
Morling, Niels, Frentz, G., Fugger, L., Georgsen, J., Jakobsen, B., Ødum, Niels & Svejgaard, A., 1992, In: Disease Markers. 9, 1, p. 35-42 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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DNA polymorphism of HLA class II genes in pauciarticular juvenile rheumatoid arthritis
Morling, Niels, Friis, J., Fugger, L., Georgsen, J., Heilmann, C., Pedersen, F. K., Ødum, Niels & Svejgaard, A., 1991, In: HLA. 38, 1, p. 16-23 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Immunogenetics of rheumatoid arthritis and primary Sjögren's syndrome: DNA polymorphism of HLA class II genes
Morling, Niels, Andersen, V., Fugger, L., Georgsen, J., Halberg, P., Oxholm, P., Ødum, Niels & Svejgaard, A., 1992, In: Disease Markers. 9, 5, p. 289-296 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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DNA polymorphism of HLA class II genes in primary biliary cirrhosis
Morling, Niels, Dalhoff, K., Fugger, L., Georgsen, J., Jakobsen, B., Ranek, L., Ødum, Niels & Svejgaard, A., 1992, In: Immunogenetics. 35, 2, p. 112-6 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
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The junctional adhesion molecule-like protein (JAML) is important for the inflammatory response during contact hypersensitivity
Mraz, Veronika, Lohmann, R. K. D., Menzel, Mandy, Hawkes, A., Vaher, Helen, Funch, Anders Boutrup, Jee, Mia Hamilton, Gadsbøll, A. S. Ø., Weber, Julie Friis, Yeung, Kelvin, Ødum, Niels, Woetmann, Anders , McKay, D., Witherden, D., Geisler, Carsten & Bonefeld, Charlotte Menne, 2023, In: Contact Dermatitis. 89, 5, p. e63-e65Research output: Contribution to journal › Journal article › Research › peer-review
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CD100 boosts the inflammatory response in the challenge phase of allergic contact dermatitis in mice
Mraz, Veronika, Funch, Anders Boutrup, Jee, Mia Hamilton, Gadsbøll, A. S. Ø., Weber, Julie Friis, Yeung, Kelvin, Lohmann, R. K. D., Hawkes, A., Ødum, Niels, Woetmann, Anders , McKay, D., Witherden, D., Geisler, Carsten & Bonefeld, Charlotte Menne, 2023, In: Contact Dermatitis. 89, 6, p. 442-452Research output: Contribution to journal › Journal article › Research › peer-review
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HLA-DP antigens in patients with chronic autoimmune thrombocytopenia (AITP)
Mueller-Eckhardt, G., Pawelec, G., Haas, R., Otto, C., Kiefel, V., Ødum, Niels & Mueller-Eckhardt, C., 1989, In: HLA. 34, 2, p. 121-6 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Cutaneous T cell lymphoma cells are targets for immune checkpoint ligand PD-L1-specific, cytotoxic T cells
Munir, S., Andersen, G. H., Woetmann, Anders , Ødum, Niels, Becker, J. C. & Andersen, Mads Hald, Nov 2013, In: Leukemia. 27, 11, p. 2251-3 3 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Immunodeficiency after allogeneic bone marrow transplantation in man. Effect of phorbol ester (phorbol myristate acetate) and calcium ionophore (A23187) in vitro
Møller, J., Hofmann, B., Langhoff, E., Damgård Jacobsen, K., Ødum, Niels, Dickmeiss, E., Ryder, L. P., Thastrup, O., Scharff, O. & Foder, B., 1989, In: Scandinavian Journal of Immunology. 30, 4, p. 441-7 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
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1,25-dihydroxyvitamin D3 selectively reduces interleukin-2 levels and proliferation of human T cell lines in vitro
Müller, K., Ødum, Niels & Bendtzen, K., 1993, In: Immunology Letters. 35, 2, p. 177-82 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Multi-gene epigenetic silencing of tumor suppressor genes in T-cell lymphoma cells; delayed expression of the p16 protein upon reversal of the silencing
Nagasawa, T., Zhang, Q., Raghunath, P. N., Wong, H. Y., El-Salem, M., Szallasi, A., Marzec, Michal Tomasz, Gimotty, P., Rook, A. H., Vonderheid, E. C., Ødum, Niels & Wasik, M. A., 2006, In: Leukemia research : a Forum for Studies on Leukemia and Normal Hemopoiesis. 30, 3, p. 303-12 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Inhibition of succinate dehydrogenase activity impairs human T cell activation and function: [Publisher correction]
Nastasi, C., Willerlev-Olsen, A., Dalhoff, K., Ford, Shayne Lavondua, Gadsbøll, A. S. Ø., Buus, Terkild Brink, Gluud, Maria, Danielsen, M., Litman, Thomas, Bonefeld, Charlotte Menne, Geisler, Carsten, Ødum, Niels & Woetmann, Anders , 2021, In: Scientific Reports. 11, 1, 1458.Research output: Contribution to journal › Journal article › Research › peer-review
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The effect of short-chain fatty acids on human monocyte-derived dendritic cells
Nastasi, C., Candela, M., Bonefeld, Charlotte Menne, Geisler, Carsten, Hansen, M., Krejsgaard, T., Biagi, E., Andersen, Mads Hald, Brigidi, P., Ødum, Niels, Litman, T. & Woetmann, Anders , 2015, In: Scientific Reports. 5, 10 p., 16148.Research output: Contribution to journal › Journal article › Research › peer-review
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Butyrate and propionate inhibit antigen-specific CD8+ T cell activation by suppressing IL-12 production by antigen-presenting cells
Nastasi, C., Fredholm, S., Willerslev-Olsen, A., Hansen, M., Bonefeld, Charlotte Menne, Geisler, Carsten, Andersen, Mads Hald, Ødum, Niels & Woetmann, Anders , Dec 2017, In: Scientific Reports. 7, 10 p., 14516.Research output: Contribution to journal › Journal article › Research › peer-review
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Analysis of CTCL cell lines reveals important differences between mycosis fungoides/Sézary syndrome vs. HTLV-1+ leukemic cell lines
Netchiporouk, E., Gantchev, J., Tsang, M., Thibault, P., Watters, A. K., Hughes, J. D. M., Ghazawi, F. M., Woetmann, Anders , Ødum, Niels, Sasseville, D. & Litvinov, I. V., 2017, In: OncoTarget. 8, 56, p. 95981-95998 18 p.Research output: Contribution to journal › Journal article › Research › peer-review
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MHC class II molecules regulate growth in human T cells
Nielsen, M., Ødum, Niels, Bendtzen, K., Ryder, L. P., Jakobsen, B. K. & Svejgaard, A., 1994, In: Experimental and Clinical Immunogenetics. 11, 1, p. 23-32 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Interleukin-2 induces tyrosine phosphorylation and nuclear translocation of stat3 in human T lymphocytes
Nielsen, M., Svejgaard, A., Skov, S. & Ødum, Niels, 1994, In: European Journal of Immunology. 24, 12, p. 3082-6 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Staphylococcal enterotoxins modulate interleukin 2 receptor expression and ligand-induced tyrosine phosphorylation of the Janus protein-tyrosine kinase 3 (Jak3) and signal transducers and activators of transcription (Stat proteins)
Nielsen, M., Svejgaard, A., Röpke, C., Nordahl, M. & Ødum, Niels, 1995, In: Proceedings of the National Academy of Science of the United States of America. 92, 24, p. 10995-9 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
ID: 14062
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Vitamin D up-regulates the vitamin D receptor by protecting it from proteasomal degradation in human CD4+ T cells
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427
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Vitamin D counteracts Mycobacterium tuberculosis-induced cathelicidin downregulation in dendritic cells and allows Th1 differentiation and IFNγ secretion
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STAT5 induces miR-21 expression in cutaneous T cell lymphoma
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Published