Niels Ødum
Professor
Skin Immunology Research Center
Blegdamsvej 3B, 2200 København N, 07 Bygning 7, Building: 07-12-86
Member of:
- 2005
- Published
The immune privilege of the eye: human retinal pigment epithelial cells selectively modulate T-cell activation in vitro.
Kaestel, C. G., Lovato, P., Ødum, Niels, Nissen, Mogens Holst & Röpke, C., 2005, In: Current Eye Research. 30, 5, p. 375-83 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Inhibition of ALK enzymatic activity in T-cell lymphoma cells induces apoptosis and suppresses proliferation and STAT3 phosphorylation independently of Jak3
Marzec, Michal Tomasz, Kasprzycka, M., Ptasznik, A., Wlodarski, P., Zhang, Q., Ødum, Niels & Wasik, M. A., 2005, In: Laboratory Investigation. 85, 12, p. 1544-54 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Cancer cells become susceptible to natural killer cell killing after exposure to histone deacetylase inhibitors due to glycogen synthase kinase-3-dependent expression of MHC class I-related chain A and B
Skov, Søren, Pedersen, M. T., Andresen, Lars, Straten, P. T., Woetmann, Anders & Ødum, Niels, 2005, In: Cancer Research. 65, 23, p. 11136-45 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2004
- Published
SOCS5 is expressed in primary B and T lymphoid cells but is dispensable for lymphocyte production and function
Brender, C., Columbus, R., Metcalf, D., Handman, E., Starr, R., Huntington, N., Tarlinton, D., Ødum, Niels, Nicholson, S. E., Nicola, N. A., Hilton, D. J. & Alexander, W. S., 2004, In: Molecular and Cellular Biology. 24, 13, p. 6094-103 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Masking of the CD3 gamma di-leucine-based motif by zeta is required for efficient T-cell receptor expression
Lauritsen, J. P. H., Bonefeld, Charlotte Menne, von Essen, Marina Rode, Nielsen, M. W., Rasmussen, A. B., Ødum, Niels, Dietrich, J. & Geisler, Carsten, 2004, In: Traffic - International Journal of Intracellular Transport. 5, 9, p. 672-84 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Proteasomal targeting and minigene repetition improve cell-surface presentation of a transfected, modified melanoma tumour antigen
Rasmussen, A. B., Zocca, M., Bonefeld, Charlotte Menne, von Essen, Marina Rode, Lauritsen, J. P., Tomra, S., Ødum, Niels & Geisler, Carsten, 2004, In: Scandinavian Journal of Immunology. 59, 2, p. 220-7 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
In vivo activation of STAT3 in cutaneous T-cell lymphoma. Evidence for an antiapoptotic function of STAT3.
Sommer, V. H., Clemmensen, O. J., Nielsen, O., Wasik, M., Lovato, P., Brender, C., Eriksen, K. W., Woetmann, Anders , Kaestel, C. G., Nissen, Mogens Holst, Ropke, C., Skov, Søren & Ødum, Niels, 2004, In: Leukemia. 18, 7, p. 1288-95 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2003
- Published
Protein phosphates 2A (PP2A) regulates IL-4- mediated STAT6 signalling
Woetmann, Anders , Nielsen, M., Brockdorff, J., Leick, V., Rieneck, K., Bendtzen, K., Geisler, C. & Ødum, Niels, 2003, In: Journal of Biological Chemistry. 278, p. 2787-2791Research output: Contribution to journal › Journal article › Research › peer-review
- Published
TCR comodulation of nonengaged TCR takes place by a protein kinase C and CD3 gamma di-leucine-based motif-dependent mechanism
Bonefeld, Charlotte Menne, Rasmussen, B. A., Lauritsen, J. P., von Essen, Marina Rode, Ødum, Niels, Andersen, P. S. & Geisler, Carsten, 2003, In: Journal of Immunology. 171, 6, p. 3003-9 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Bi-phasic effect of interferon (IFN)-alpha: IFN-alpha up- and down-regulates interleukin-4 signaling in human T cells
Eriksen, K. W., Sommer, V. H., Woetmann, Anders , Rasmussen, A. B., Brender, C., Svejgaard, A., Skov, Søren, Geisler, Carsten & Ødum, Niels, 2003, In: Journal of Biological Chemistry. 279, 1, p. 169-76 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Constitutive STAT3 activation in intestinal T cells from patients with Crohn's disease
Lovato, P., Brender, C., Agnholt, J., Kelsen, J., Kaltoft, K., Svejgaard, A., Eriksen, K. W., Woetmann, Anders & Ødum, Niels, 2003, In: Journal of Biological Chemistry. 278, 19, p. 16777-81 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Histone deacetylase inhibitors: a new class of immunosuppressors targeting a novel signal pathway essential for CD154 expression
Skov, Søren, Rieneck, K., Bovin, L. F., Skak, K., Tomra, S., Michelsen, B. K. & Ødum, Niels, 2003, In: Blood. 101(4), p. 1430-1438Research output: Contribution to journal › Journal article › Research › peer-review
- 2002
- Published
Ligand-induced TCR down-regulation is not dependent on constitutive TCR cycling
Dietrich, J., Bonefeld, Charlotte Menne, Lauritsen, J. P. H., von Essen, Marina Rode, Rasmussen, B. A., Ødum, Niels & Geisler, Carsten, 2002, In: Journal of Immunology. 168, 11, p. 5434-40 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Human retinal pigment epithelial cells inhibit proliferation and IL2R expression of activated T cells.
Kaestel, C. G., Jørgensen, A., Nielsen, M., Eriksen, K. W., Ødum, Niels, Nissen, Mogens Holst & Röpke, C., 2002, In: Experimental Eye Research. 74, 5, p. 627-37 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
SHP2 regulates IL-2 induced MAPK activation, but not Stat3 or Stat5 tyrosine phosphorylation, in cutaneous T cell lymphoma cells
Lundin Brockdorff, J., Woetmann, Anders , Mustelin, T., Kaltoft, K., Zhang, Q., Wasik, M. A., Röpke, C. & Ødum, Niels, 2002, In: Cytokine. 20, 4, p. 141-7 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
IL-15 induces unspecific effector functions in human peptide-specific CD8+ T-cell cultures.
Lyngstrand, S. T., Würtzen, P. A., Ødum, Niels, Nissen, Mogens Holst & Röpke, C., 2002, In: Scandinavian Journal of Immunology. 56, 6, p. 602-10 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Endo- and exocytic rate constants for spontaneous and protein kinase C-activated T cell receptor cycling
Bonefeld, Charlotte Menne, Møller Sørensen, T., Siersma, Volkert Dirk, von Essen, Marina Rode, Ødum, Niels & Geisler, Carsten, 2002, In: European Journal of Immunology. 32, 3, p. 616-26 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Spontaneous interleukin-5 production in cutaneous T-cell lymphoma lines is mediated by constitutively activated Stat3
Nielsen, M., Nissen, Mogens Holst, Gerwien, J., Zocca, M., Rasmussen, H. M., Nakajima, K., Röpke, C., Geisler, Carsten, Kaltoft, K. & Ødum, Niels, 2002, In: Blood. 99, 3, p. 973-7 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Protein phosphatase 2A (PP2A) regulates interleukin-4-mediated STAT6 signaling
Woetmann, Anders , Brockdorff, J., Lovato, P., Nielsen, M., Leick, V., Rieneck, K., Svejgaard, A., Geisler, Carsten & Ødum, Niels, 2002, In: Journal of Biological Chemistry. 278, 5, p. 2787-91 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Multilevel dysregulation of STAT3 activation in anaplastic lymphoma kinase-positive T/null-cell lymphoma
Zhang, Q., Raghunath, P. N., Xue, L., Majewski, M., Carpentieri, D. F., Ødum, Niels, Morris, S., Skorski, T. & Wasik, M. A., 2002, In: Journal of Immunology. 168, 1, p. 466-74 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The CD3 gamma leucine-based receptor-sorting motif is required for efficient ligand-mediated TCR down-regulation
von Essen, Marina Rode, Bonefeld, Charlotte Menne, Nielsen, B. L., Lauritsen, J. P. H., Dietrich, J., Andersen, P. S., Karjalainen, K., Ødum, Niels & Geisler, Carsten, 2002, In: Journal of Immunology. 168, 9, p. 4519-23 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2001
- Published
Interferon-alpha induces transient suppressors of cytokine signalling expression in human T cells
Brender, C., Nielsen, M., Röpke, C., Nissen, M. H., Svejgaard, A., Billestrup, N., Geisler, Carsten & Ødum, Niels, 2001, In: Experimental and Clinical Immunogenetics. 18, 2, p. 80-5 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
STAT3-mediated constitutive expression of SOCS-3 in cutaneous T-cell lymphoma
Brender, C., Nielsen, M., Kaltoft, K., Mikkelsen, G., Zhang, Q., Wasik, M., Billestrup, N. & Ødum, Niels, 2001, In: Blood. 97, 4, p. 1056-62 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Gab2 is phosphorylated on tyrosine upon interleukin-2/interleukin-15 stimulation in mycosis-fungoides-derived tumor T cells and associates inducibly with SHP-2 and Stat5a
Brockdorff, J. L., Gu, H., Mustelin, T., Kaltoft, K., Geisler, Carsten, Röpke, C. & Ødum, Niels, 2001, In: Experimental and Clinical Immunogenetics. 18, 2, p. 86-95 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Oligonucleotide fishing for STAT6: cross-talk between IL-4 and chemokines.
Eriksen, K. W., Nielsen, M., Kaltoft, K., Svejgaard, A., Nissen, Mogens Holst, Röpke, C. & Ødum, Niels, 2001, In: Experimental and Clinical Immunogenetics. 18, 4, p. 233-41 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Radically altered T cell receptor signaling in glycopeptide-specific T cell hybridoma induced by antigen with minimal differences in the glycan group
Jensen, T., Nielsen, M., Gad, M., Hansen, P., Komba, S., Meldal, M., Ødum, Niels & Werdelin, O., 2001, In: European Journal of Immunology. 31, 11, p. 3197-206 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Superantigen presentation by human retinal pigment epithelial cells to T cells is dependent on CD2-CD58 and CD18-CD54 molecule interactions.
Jørgensen, A., Junker, N., Kaestel, C. G., Liang, Y., Wiencke, A., la Cour, M., Lui, G. M., Ødum, Niels, Nissen, Mogens Holst & Röpke, C., 2001, In: Experimental Eye Research. 73, 5, p. 723-33 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Induction of cytotoxic CD8+CD56+ T cells from human thymocytes by interleukin-15.
Thulesen, S., Nissen, Mogens Holst, Ødum, Niels & Röpke, C., 2001, In: Journal of Interferon & Cytokine Research. 21, 11, p. 905-11 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2000
- Published
beta2-adaptin is constitutively de-phosphorylated by serine/threonine protein phosphatase PP2A and phosphorylated by a staurosporine-sensitive kinase
Lauritsen, J. P. H., Bonefeld, Charlotte Menne, Kastrup, J., Dietrich, J., Ødum, Niels & Geisler, Carsten, 2000, In: BBA General Subjects. 1497, 3, p. 297-307 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Ceramide-induced TCR up-regulation
Bonefeld, Charlotte Menne, Lauritsen, J. P. H., Dietrich, J., Kastrup, J., Wegener, A. M., Ødum, Niels & Geisler, Carsten, 2000, In: Journal of Immunology. 165, 6, p. 3065-72 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Low prevalence of antibodies and other plasma factors binding to CC chemokines and IL-2 in HIV-positive patients
Meyer, C. N., Svenson, M., Schade Larsen, C., Ødum, Niels, Skinhøj, P. & Bendtzen, K., 2000, In: Acta Pathologica Microbiologica et Immunologica Scandinavica. 108, 2, p. 122-30 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Low prevalence of antibodies and other factors binding to CC-chemokines and IL-2 in HIV-positive patients
Meyer, C. N., Svenson, M., Larsen, C. S., Ødum, Niels, Skinhøj, P. & Bendzen, K., 2000, In: APMIS : Acta pathologica, microbiologica et immunologica Scandinavica. Supplementum. 108, p. 122-130Research output: Contribution to journal › Journal article › Research › peer-review
- Published
IL-2 and IL-15 regulate CD154 expression on activated CD4 T cells
Skov, S., Bonyhadi, M., Ødum, Niels & Ledbetter, J. A., 2000, In: Journal of Immunology. 164, 7, p. 3500-5 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Lack of Phosphotyrosine Phosphatase SHP-1 Expression in Malignant T-Cell Lymphoma Cells Results from Methylation of the SHP-1 Promoter
Zhang, Q., Raghunath, P. N., Vonderheid, E., Ødum, Niels & Wasik, M. A., 2000, In: American Journal of Pathology. 157, 4, p. 1137-46 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Lack of phosphotyrosine phosphatase SHP-1 expression in malignant T cell lymphoma cells results from methylation of the SHP-1 promotor
Zhang, Q., Raghunath, P. N., Vonderheid, E., Ødum, Niels & Wasik, M. A., 2000, In: American Journal of Pathology. 157, p. 1137-1146Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Medforfatter til "Celleinteraktioner og regulering"
Ødum, Niels, 2000, Basal og klinisk immunologi. FADL's Forlag, p. -Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Education
- 1999
- Published
Inhibition of T cell proliferation by selective block of Ca(2+)-activated K(+) channels
Jensen, B. S., Ødum, Niels, Jorgensen, N. K., Christophersen, P. & Olesen, Søren-Peter, 1999, In: Proceedings of the National Academy of Science of the United States of America. 96, 19, p. 10917-21 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Inhibition of T cell proliferation by selective block of Ca2+-activated K+ channels
Jensen, B. S., Ødum, Niels, Jørgensen, N. K., Christophersen, P. & Olesen, Søren-Peter, 1999, In: Proceedings of the National Academy of Science of the United States of America. 96, p. 10917-10921Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Rapid tyrosine phosphorylation of Lck following ligation of the tumor-associated cell surface molecule A6H
Labuda, T., Gerwien, J., Ødum, Niels & Dohlsten, M., 1999, In: International Immunology. 11, 3, p. 427-33 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The CC-chemokine receptor 5 (CCR5) is a marker of, but not essential for the development of human Th1 cells
Ødum, Niels, Bregenholt, S., Eriksen, K. W., Skov, S., Ryder, L. P., Bendtzen, K., Van Neerven, R. J., Svejgaard, A. & Garred, Peter, 1999, In: HLA. 54, 6, p. 572-7 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
IKca Channel Blocking compounds/immunosuppressiva
Olesen, S., Jensen, B. S., Jørgensen, T. H., Strøbæk, D., Christoffersen, P. & Ødum, Niels, 1999, PCT.Research output: Book/Report › Book › Research
- Published
Inhibition of Protein Phosphatase 2A induces serine/threonine phosphorylation and functional inhibition of STAT3
Woetmann, A., Nielsen, M., Christensen, S. T., Brockdorff, J., Kaltoft, K., Brender, C., Skov, S., Svejgaard, A., Leick, V. & Ødum, Niels, 1999, In: Proc. Natl. Acad. Sci.. 96, p. 10620-10625Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The CC-chemokine receptor 5 is a marker of, but not essential for the development of human TH1 cells
Ødum, Niels, Bregenholt, S., Eriksen, K., Skov, S., Ryder, L. P., Bendtzen, K., van Nerveen, R. J. J., Svejgaard, A. & Garred, P., 1999, In: HLA. 54, p. 572-577Research output: Contribution to journal › Journal article › Research › peer-review
- 1998
- Published
Leucine-based receptor sorting motifs are dependent on the spacing relative to the plasma membrane
Geisler, Carsten, Dietrich, J., Nielsen, B. L., Kastrup, J., Lauritsen, J. P. H., Ødum, Niels & Bartels, Mette Damkjær, 1998, In: Journal of Biological Chemistry. 273, 33, p. 21316-23 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Stahpylococcal enterotoxin A modulates IL-15 responses in human T cells
Gerwien, J., Nielsen, M., Pedersen, M. N., Svejgaard, A., Röpke, C. & Ødum, Niels, 1998, In: HLA. 51, p. 164-173Research output: Contribution to journal › Journal article › Research
- Published
Interleukin 2 and 15 activate Stat3alpha in human T lymphocytes
Nielsen, M., Svendsen, Mette Nordahl, Svejgaard, A. & Ødum, Niels, 1998, In: Cytokine. 10, 10, p. 735-8 3 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Interleukin-2 and -15 activate Stat 3a in human T lymphocytes
Nielsen, M., Pedersen, M. N., Svejgaard, A. & Ødum, Niels, 1998, In: Cytokine. 10, p. 735-738Research output: Contribution to journal › Journal article › Research
- Published
Activation of Stat-3 is involved in the induction of apoptosis after ligation of major histocompatibility complex class I molecules on human Jurkat T cells
Skov, S., Nielsen, M., Bregenholt, S., Ødum, Niels & Claesson, Mogens Helweg, 1998, In: Blood. 91, 10, p. 3566-73 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
MHC class I ligation of human T cells activates the TYK-2 kinase and induces tyrosine phosphorylation, nuclear translocation, and DNA binding of the Stat3 transcription factor
Skov, Søren, Nielsen, M., Bregenholt, S., Ødum, Niels & Claesson, Mogens Helweg, 1998, In: Blood. 91, p. 3566-3573Research output: Contribution to journal › Journal article › Research › peer-review
- 1997
- Published
Human Thymic epithelial cells present superantigens to T cell lines and Thymolytes
Jørgensen, A. Y., Ødum, Niels & Röpke, C., 1997, In: Experimental and Clinical Immunogenetics. 13, p. 192-203Research output: Contribution to journal › Journal article › Research › peer-review
ID: 14062
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Vitamin D up-regulates the vitamin D receptor by protecting it from proteasomal degradation in human CD4+ T cells
Research output: Contribution to journal › Journal article › Research › peer-review
Published -
427
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Vitamin D counteracts Mycobacterium tuberculosis-induced cathelicidin downregulation in dendritic cells and allows Th1 differentiation and IFNγ secretion
Research output: Contribution to journal › Journal article › Research › peer-review
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351
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STAT5 induces miR-21 expression in cutaneous T cell lymphoma
Research output: Contribution to journal › Journal article › Research › peer-review
Published