Niels Ødum

Niels Ødum

Professor

Member of:


    1. 2005
    2. Published

      The immune privilege of the eye: human retinal pigment epithelial cells selectively modulate T-cell activation in vitro.

      Kaestel, C. G., Lovato, P., Ødum, Niels, Nissen, Mogens Holst & Röpke, C., 2005, In: Current Eye Research. 30, 5, p. 375-83 8 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    3. Published

      Inhibition of ALK enzymatic activity in T-cell lymphoma cells induces apoptosis and suppresses proliferation and STAT3 phosphorylation independently of Jak3

      Marzec, Michal Tomasz, Kasprzycka, M., Ptasznik, A., Wlodarski, P., Zhang, Q., Ødum, Niels & Wasik, M. A., 2005, In: Laboratory Investigation. 85, 12, p. 1544-54 10 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    4. Published

      Cancer cells become susceptible to natural killer cell killing after exposure to histone deacetylase inhibitors due to glycogen synthase kinase-3-dependent expression of MHC class I-related chain A and B

      Skov, Søren, Pedersen, M. T., Andresen, Lars, Straten, P. T., Woetmann, Anders & Ødum, Niels, 2005, In: Cancer Research. 65, 23, p. 11136-45 9 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    5. 2004
    6. Published

      SOCS5 is expressed in primary B and T lymphoid cells but is dispensable for lymphocyte production and function

      Brender, C., Columbus, R., Metcalf, D., Handman, E., Starr, R., Huntington, N., Tarlinton, D., Ødum, Niels, Nicholson, S. E., Nicola, N. A., Hilton, D. J. & Alexander, W. S., 2004, In: Molecular and Cellular Biology. 24, 13, p. 6094-103 9 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    7. Published

      Masking of the CD3 gamma di-leucine-based motif by zeta is required for efficient T-cell receptor expression

      Lauritsen, J. P. H., Bonefeld, Charlotte Menne, von Essen, Marina Rode, Nielsen, M. W., Rasmussen, A. B., Ødum, Niels, Dietrich, J. & Geisler, Carsten, 2004, In: Traffic - International Journal of Intracellular Transport. 5, 9, p. 672-84 12 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    8. Published

      Proteasomal targeting and minigene repetition improve cell-surface presentation of a transfected, modified melanoma tumour antigen

      Rasmussen, A. B., Zocca, M., Bonefeld, Charlotte Menne, von Essen, Marina Rode, Lauritsen, J. P., Tomra, S., Ødum, Niels & Geisler, Carsten, 2004, In: Scandinavian Journal of Immunology. 59, 2, p. 220-7 7 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    9. Published

      In vivo activation of STAT3 in cutaneous T-cell lymphoma. Evidence for an antiapoptotic function of STAT3.

      Sommer, V. H., Clemmensen, O. J., Nielsen, O., Wasik, M., Lovato, P., Brender, C., Eriksen, K. W., Woetmann, Anders , Kaestel, C. G., Nissen, Mogens Holst, Ropke, C., Skov, Søren & Ødum, Niels, 2004, In: Leukemia. 18, 7, p. 1288-95 7 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    10. 2003
    11. Published

      Protein phosphates 2A (PP2A) regulates IL-4- mediated STAT6 signalling

      Woetmann, Anders , Nielsen, M., Brockdorff, J., Leick, V., Rieneck, K., Bendtzen, K., Geisler, C. & Ødum, Niels, 2003, In: Journal of Biological Chemistry. 278, p. 2787-2791

      Research output: Contribution to journalJournal articleResearchpeer-review

    12. Published

      TCR comodulation of nonengaged TCR takes place by a protein kinase C and CD3 gamma di-leucine-based motif-dependent mechanism

      Bonefeld, Charlotte Menne, Rasmussen, B. A., Lauritsen, J. P., von Essen, Marina Rode, Ødum, Niels, Andersen, P. S. & Geisler, Carsten, 2003, In: Journal of Immunology. 171, 6, p. 3003-9 6 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    13. Published

      Bi-phasic effect of interferon (IFN)-alpha: IFN-alpha up- and down-regulates interleukin-4 signaling in human T cells

      Eriksen, K. W., Sommer, V. H., Woetmann, Anders , Rasmussen, A. B., Brender, C., Svejgaard, A., Skov, Søren, Geisler, Carsten & Ødum, Niels, 2003, In: Journal of Biological Chemistry. 279, 1, p. 169-76 7 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    14. Published

      Constitutive STAT3 activation in intestinal T cells from patients with Crohn's disease

      Lovato, P., Brender, C., Agnholt, J., Kelsen, J., Kaltoft, K., Svejgaard, A., Eriksen, K. W., Woetmann, Anders & Ødum, Niels, 2003, In: Journal of Biological Chemistry. 278, 19, p. 16777-81 4 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    15. Published

      Histone deacetylase inhibitors: a new class of immunosuppressors targeting a novel signal pathway essential for CD154 expression

      Skov, Søren, Rieneck, K., Bovin, L. F., Skak, K., Tomra, S., Michelsen, B. K. & Ødum, Niels, 2003, In: Blood. 101(4), p. 1430-1438

      Research output: Contribution to journalJournal articleResearchpeer-review

    16. 2002
    17. Published

      Ligand-induced TCR down-regulation is not dependent on constitutive TCR cycling

      Dietrich, J., Bonefeld, Charlotte Menne, Lauritsen, J. P. H., von Essen, Marina Rode, Rasmussen, B. A., Ødum, Niels & Geisler, Carsten, 2002, In: Journal of Immunology. 168, 11, p. 5434-40 6 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    18. Published

      Human retinal pigment epithelial cells inhibit proliferation and IL2R expression of activated T cells.

      Kaestel, C. G., Jørgensen, A., Nielsen, M., Eriksen, K. W., Ødum, Niels, Nissen, Mogens Holst & Röpke, C., 2002, In: Experimental Eye Research. 74, 5, p. 627-37 10 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    19. Published

      SHP2 regulates IL-2 induced MAPK activation, but not Stat3 or Stat5 tyrosine phosphorylation, in cutaneous T cell lymphoma cells

      Lundin Brockdorff, J., Woetmann, Anders , Mustelin, T., Kaltoft, K., Zhang, Q., Wasik, M. A., Röpke, C. & Ødum, Niels, 2002, In: Cytokine. 20, 4, p. 141-7 6 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    20. Published

      IL-15 induces unspecific effector functions in human peptide-specific CD8+ T-cell cultures.

      Lyngstrand, S. T., Würtzen, P. A., Ødum, Niels, Nissen, Mogens Holst & Röpke, C., 2002, In: Scandinavian Journal of Immunology. 56, 6, p. 602-10 8 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    21. Published

      Endo- and exocytic rate constants for spontaneous and protein kinase C-activated T cell receptor cycling

      Bonefeld, Charlotte Menne, Møller Sørensen, T., Siersma, Volkert Dirk, von Essen, Marina Rode, Ødum, Niels & Geisler, Carsten, 2002, In: European Journal of Immunology. 32, 3, p. 616-26 10 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    22. Published

      Spontaneous interleukin-5 production in cutaneous T-cell lymphoma lines is mediated by constitutively activated Stat3

      Nielsen, M., Nissen, Mogens Holst, Gerwien, J., Zocca, M., Rasmussen, H. M., Nakajima, K., Röpke, C., Geisler, Carsten, Kaltoft, K. & Ødum, Niels, 2002, In: Blood. 99, 3, p. 973-7 4 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    23. Published

      Protein phosphatase 2A (PP2A) regulates interleukin-4-mediated STAT6 signaling

      Woetmann, Anders , Brockdorff, J., Lovato, P., Nielsen, M., Leick, V., Rieneck, K., Svejgaard, A., Geisler, Carsten & Ødum, Niels, 2002, In: Journal of Biological Chemistry. 278, 5, p. 2787-91 4 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    24. Published

      Multilevel dysregulation of STAT3 activation in anaplastic lymphoma kinase-positive T/null-cell lymphoma

      Zhang, Q., Raghunath, P. N., Xue, L., Majewski, M., Carpentieri, D. F., Ødum, Niels, Morris, S., Skorski, T. & Wasik, M. A., 2002, In: Journal of Immunology. 168, 1, p. 466-74 8 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    25. Published

      The CD3 gamma leucine-based receptor-sorting motif is required for efficient ligand-mediated TCR down-regulation

      von Essen, Marina Rode, Bonefeld, Charlotte Menne, Nielsen, B. L., Lauritsen, J. P. H., Dietrich, J., Andersen, P. S., Karjalainen, K., Ødum, Niels & Geisler, Carsten, 2002, In: Journal of Immunology. 168, 9, p. 4519-23 4 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    26. 2001
    27. Published

      Interferon-alpha induces transient suppressors of cytokine signalling expression in human T cells

      Brender, C., Nielsen, M., Röpke, C., Nissen, M. H., Svejgaard, A., Billestrup, N., Geisler, Carsten & Ødum, Niels, 2001, In: Experimental and Clinical Immunogenetics. 18, 2, p. 80-5 5 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    28. Published

      STAT3-mediated constitutive expression of SOCS-3 in cutaneous T-cell lymphoma

      Brender, C., Nielsen, M., Kaltoft, K., Mikkelsen, G., Zhang, Q., Wasik, M., Billestrup, N. & Ødum, Niels, 2001, In: Blood. 97, 4, p. 1056-62 6 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    29. Published

      Gab2 is phosphorylated on tyrosine upon interleukin-2/interleukin-15 stimulation in mycosis-fungoides-derived tumor T cells and associates inducibly with SHP-2 and Stat5a

      Brockdorff, J. L., Gu, H., Mustelin, T., Kaltoft, K., Geisler, Carsten, Röpke, C. & Ødum, Niels, 2001, In: Experimental and Clinical Immunogenetics. 18, 2, p. 86-95 9 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    30. Published

      Oligonucleotide fishing for STAT6: cross-talk between IL-4 and chemokines.

      Eriksen, K. W., Nielsen, M., Kaltoft, K., Svejgaard, A., Nissen, Mogens Holst, Röpke, C. & Ødum, Niels, 2001, In: Experimental and Clinical Immunogenetics. 18, 4, p. 233-41 8 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    31. Published

      Radically altered T cell receptor signaling in glycopeptide-specific T cell hybridoma induced by antigen with minimal differences in the glycan group

      Jensen, T., Nielsen, M., Gad, M., Hansen, P., Komba, S., Meldal, M., Ødum, Niels & Werdelin, O., 2001, In: European Journal of Immunology. 31, 11, p. 3197-206 9 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    32. Published

      Superantigen presentation by human retinal pigment epithelial cells to T cells is dependent on CD2-CD58 and CD18-CD54 molecule interactions.

      Jørgensen, A., Junker, N., Kaestel, C. G., Liang, Y., Wiencke, A., la Cour, M., Lui, G. M., Ødum, Niels, Nissen, Mogens Holst & Röpke, C., 2001, In: Experimental Eye Research. 73, 5, p. 723-33 10 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    33. Published

      Induction of cytotoxic CD8+CD56+ T cells from human thymocytes by interleukin-15.

      Thulesen, S., Nissen, Mogens Holst, Ødum, Niels & Röpke, C., 2001, In: Journal of Interferon & Cytokine Research. 21, 11, p. 905-11 6 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    34. 2000
    35. Published

      beta2-adaptin is constitutively de-phosphorylated by serine/threonine protein phosphatase PP2A and phosphorylated by a staurosporine-sensitive kinase

      Lauritsen, J. P. H., Bonefeld, Charlotte Menne, Kastrup, J., Dietrich, J., Ødum, Niels & Geisler, Carsten, 2000, In: BBA General Subjects. 1497, 3, p. 297-307 10 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    36. Published

      Ceramide-induced TCR up-regulation

      Bonefeld, Charlotte Menne, Lauritsen, J. P. H., Dietrich, J., Kastrup, J., Wegener, A. M., Ødum, Niels & Geisler, Carsten, 2000, In: Journal of Immunology. 165, 6, p. 3065-72 7 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    37. Published

      Low prevalence of antibodies and other plasma factors binding to CC chemokines and IL-2 in HIV-positive patients

      Meyer, C. N., Svenson, M., Schade Larsen, C., Ødum, Niels, Skinhøj, P. & Bendtzen, K., 2000, In: Acta Pathologica Microbiologica et Immunologica Scandinavica. 108, 2, p. 122-30 9 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    38. Published

      Low prevalence of antibodies and other factors binding to CC-chemokines and IL-2 in HIV-positive patients

      Meyer, C. N., Svenson, M., Larsen, C. S., Ødum, Niels, Skinhøj, P. & Bendzen, K., 2000, In: APMIS : Acta pathologica, microbiologica et immunologica Scandinavica. Supplementum. 108, p. 122-130

      Research output: Contribution to journalJournal articleResearchpeer-review

    39. Published

      IL-2 and IL-15 regulate CD154 expression on activated CD4 T cells

      Skov, S., Bonyhadi, M., Ødum, Niels & Ledbetter, J. A., 2000, In: Journal of Immunology. 164, 7, p. 3500-5 5 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    40. Published

      Lack of Phosphotyrosine Phosphatase SHP-1 Expression in Malignant T-Cell Lymphoma Cells Results from Methylation of the SHP-1 Promoter

      Zhang, Q., Raghunath, P. N., Vonderheid, E., Ødum, Niels & Wasik, M. A., 2000, In: American Journal of Pathology. 157, 4, p. 1137-46 9 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    41. Published

      Lack of phosphotyrosine phosphatase SHP-1 expression in malignant T cell lymphoma cells results from methylation of the SHP-1 promotor

      Zhang, Q., Raghunath, P. N., Vonderheid, E., Ødum, Niels & Wasik, M. A., 2000, In: American Journal of Pathology. 157, p. 1137-1146

      Research output: Contribution to journalJournal articleResearchpeer-review

    42. Published

      Medforfatter til "Celleinteraktioner og regulering"

      Ødum, Niels, 2000, Basal og klinisk immunologi. FADL's Forlag, p. -

      Research output: Chapter in Book/Report/Conference proceedingBook chapterEducation

    43. 1999
    44. Published

      Inhibition of T cell proliferation by selective block of Ca(2+)-activated K(+) channels

      Jensen, B. S., Ødum, Niels, Jorgensen, N. K., Christophersen, P. & Olesen, Søren-Peter, 1999, In: Proceedings of the National Academy of Science of the United States of America. 96, 19, p. 10917-21 4 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    45. Published

      Inhibition of T cell proliferation by selective block of Ca2+-activated K+ channels

      Jensen, B. S., Ødum, Niels, Jørgensen, N. K., Christophersen, P. & Olesen, Søren-Peter, 1999, In: Proceedings of the National Academy of Science of the United States of America. 96, p. 10917-10921

      Research output: Contribution to journalJournal articleResearchpeer-review

    46. Published

      Rapid tyrosine phosphorylation of Lck following ligation of the tumor-associated cell surface molecule A6H

      Labuda, T., Gerwien, J., Ødum, Niels & Dohlsten, M., 1999, In: International Immunology. 11, 3, p. 427-33 6 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    47. Published

      The CC-chemokine receptor 5 (CCR5) is a marker of, but not essential for the development of human Th1 cells

      Ødum, Niels, Bregenholt, S., Eriksen, K. W., Skov, S., Ryder, L. P., Bendtzen, K., Van Neerven, R. J., Svejgaard, A. & Garred, Peter, 1999, In: HLA. 54, 6, p. 572-7 6 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    48. Published

      IKca Channel Blocking compounds/immunosuppressiva

      Olesen, S., Jensen, B. S., Jørgensen, T. H., Strøbæk, D., Christoffersen, P. & Ødum, Niels, 1999, PCT.

      Research output: Book/ReportBookResearch

    49. Published

      Inhibition of Protein Phosphatase 2A induces serine/threonine phosphorylation and functional inhibition of STAT3

      Woetmann, A., Nielsen, M., Christensen, S. T., Brockdorff, J., Kaltoft, K., Brender, C., Skov, S., Svejgaard, A., Leick, V. & Ødum, Niels, 1999, In: Proc. Natl. Acad. Sci.. 96, p. 10620-10625

      Research output: Contribution to journalJournal articleResearchpeer-review

    50. Published

      The CC-chemokine receptor 5 is a marker of, but not essential for the development of human TH1 cells

      Ødum, Niels, Bregenholt, S., Eriksen, K., Skov, S., Ryder, L. P., Bendtzen, K., van Nerveen, R. J. J., Svejgaard, A. & Garred, P., 1999, In: HLA. 54, p. 572-577

      Research output: Contribution to journalJournal articleResearchpeer-review

    51. 1998
    52. Published

      Leucine-based receptor sorting motifs are dependent on the spacing relative to the plasma membrane

      Geisler, Carsten, Dietrich, J., Nielsen, B. L., Kastrup, J., Lauritsen, J. P. H., Ødum, Niels & Bartels, Mette Damkjær, 1998, In: Journal of Biological Chemistry. 273, 33, p. 21316-23 7 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    53. Published

      Stahpylococcal enterotoxin A modulates IL-15 responses in human T cells

      Gerwien, J., Nielsen, M., Pedersen, M. N., Svejgaard, A., Röpke, C. & Ødum, Niels, 1998, In: HLA. 51, p. 164-173

      Research output: Contribution to journalJournal articleResearch

    54. Published

      Interleukin 2 and 15 activate Stat3alpha in human T lymphocytes

      Nielsen, M., Svendsen, Mette Nordahl, Svejgaard, A. & Ødum, Niels, 1998, In: Cytokine. 10, 10, p. 735-8 3 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    55. Published

      Interleukin-2 and -15 activate Stat 3a in human T lymphocytes

      Nielsen, M., Pedersen, M. N., Svejgaard, A. & Ødum, Niels, 1998, In: Cytokine. 10, p. 735-738

      Research output: Contribution to journalJournal articleResearch

    56. Published

      Activation of Stat-3 is involved in the induction of apoptosis after ligation of major histocompatibility complex class I molecules on human Jurkat T cells

      Skov, S., Nielsen, M., Bregenholt, S., Ødum, Niels & Claesson, Mogens Helweg, 1998, In: Blood. 91, 10, p. 3566-73 7 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    57. Published

      MHC class I ligation of human T cells activates the TYK-2 kinase and induces tyrosine phosphorylation, nuclear translocation, and DNA binding of the Stat3 transcription factor

      Skov, Søren, Nielsen, M., Bregenholt, S., Ødum, Niels & Claesson, Mogens Helweg, 1998, In: Blood. 91, p. 3566-3573

      Research output: Contribution to journalJournal articleResearchpeer-review

    58. 1997
    59. Published

      Human Thymic epithelial cells present superantigens to T cell lines and Thymolytes

      Jørgensen, A. Y., Ødum, Niels & Röpke, C., 1997, In: Experimental and Clinical Immunogenetics. 13, p. 192-203

      Research output: Contribution to journalJournal articleResearchpeer-review

    ID: 14062