Repeated exposure to hair dye induces regulatory T cells in mice

Research output: Contribution to journalJournal articleResearchpeer-review

We have recently shown that commercial p-phenylenediamine (PPD)-containing hair dyes are potent immune activators that lead to severe contact hypersensitivity in an animal model. However, only a minority of people exposed to permanent hair dyes develops symptomatic contact hypersensitivity. This suggests that the majority of people exposed to hair dyes does not become sensitized or develop immunological tolerance.
Original languageEnglish
JournalBritish Journal of Dermatology
Volume163
Issue number5
Pages (from-to)992-8
Number of pages7
ISSN0007-0963
DOIs
Publication statusPublished - 2010

    Research areas

  • Animals, Cell Proliferation, Dermatitis, Allergic Contact, Disease Models, Animal, Ear, External, Flow Cytometry, Hair Dyes, Immunohistochemistry, Inflammation, Interferon-gamma, Mice, Mice, Inbred BALB C, T-Lymphocytes, Regulatory

ID: 33732598