Niels Ødum

Niels Ødum

Professor

Member of:

    ORCID: 0000-0003-3135-5624

    Publication year:
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    101 - 150 out of 325Page size: 50
    1. 2001
    2. Published

      Oligonucleotide fishing for STAT6: cross-talk between IL-4 and chemokines.

      Eriksen, K. W., Nielsen, M., Kaltoft, K., Svejgaard, A., Nissen, Mogens Holst, Röpke, C. & Ødum, Niels, 2001, In: Experimental and Clinical Immunogenetics. 18, 4, p. 233-41 8 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    3. Published

      Radically altered T cell receptor signaling in glycopeptide-specific T cell hybridoma induced by antigen with minimal differences in the glycan group

      Jensen, T., Nielsen, M., Gad, M., Hansen, P., Komba, S., Meldal, M., Ødum, Niels & Werdelin, O., 2001, In: European Journal of Immunology. 31, 11, p. 3197-206 9 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    4. Published

      STAT3-mediated constitutive expression of SOCS-3 in cutaneous T-cell lymphoma

      Brender, C., Nielsen, M., Kaltoft, K., Mikkelsen, G., Zhang, Q., Wasik, M., Billestrup, N. & Ødum, Niels, 2001, In: Blood. 97, 4, p. 1056-62 6 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    5. Published

      Superantigen presentation by human retinal pigment epithelial cells to T cells is dependent on CD2-CD58 and CD18-CD54 molecule interactions.

      Jørgensen, A., Junker, N., Kaestel, C. G., Liang, Y., Wiencke, A., la Cour, M., Lui, G. M., Ødum, Niels, Nissen, Mogens Holst & Röpke, C., 2001, In: Experimental Eye Research. 73, 5, p. 723-33 10 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    6. 2002
    7. Published

      Endo- and exocytic rate constants for spontaneous and protein kinase C-activated T cell receptor cycling

      Bonefeld, Charlotte Menne, Møller Sørensen, T., Siersma, Volkert Dirk, von Essen, Marina Rode, Ødum, Niels & Geisler, Carsten, 2002, In: European Journal of Immunology. 32, 3, p. 616-26 10 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    8. Published

      Human retinal pigment epithelial cells inhibit proliferation and IL2R expression of activated T cells.

      Kaestel, C. G., Jørgensen, A., Nielsen, M., Eriksen, K. W., Ødum, Niels, Nissen, Mogens Holst & Röpke, C., 2002, In: Experimental Eye Research. 74, 5, p. 627-37 10 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    9. Published

      IL-15 induces unspecific effector functions in human peptide-specific CD8+ T-cell cultures.

      Lyngstrand, S. T., Würtzen, P. A., Ødum, Niels, Nissen, Mogens Holst & Röpke, C., 2002, In: Scandinavian Journal of Immunology. 56, 6, p. 602-10 8 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    10. Published

      Ligand-induced TCR down-regulation is not dependent on constitutive TCR cycling

      Dietrich, J., Bonefeld, Charlotte Menne, Lauritsen, J. P. H., von Essen, Marina Rode, Rasmussen, B. A., Ødum, Niels & Geisler, Carsten, 2002, In: Journal of Immunology. 168, 11, p. 5434-40 6 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    11. Published

      Multilevel dysregulation of STAT3 activation in anaplastic lymphoma kinase-positive T/null-cell lymphoma

      Zhang, Q., Raghunath, P. N., Xue, L., Majewski, M., Carpentieri, D. F., Ødum, Niels, Morris, S., Skorski, T. & Wasik, M. A., 2002, In: Journal of Immunology. 168, 1, p. 466-74 8 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    12. Published

      Protein phosphatase 2A (PP2A) regulates interleukin-4-mediated STAT6 signaling

      Woetmann, Anders , Brockdorff, J., Lovato, P., Nielsen, M., Leick, V., Rieneck, K., Svejgaard, A., Geisler, Carsten & Ødum, Niels, 2002, In: Journal of Biological Chemistry. 278, 5, p. 2787-91 4 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    13. Published

      SHP2 regulates IL-2 induced MAPK activation, but not Stat3 or Stat5 tyrosine phosphorylation, in cutaneous T cell lymphoma cells

      Lundin Brockdorff, J., Woetmann, Anders , Mustelin, T., Kaltoft, K., Zhang, Q., Wasik, M. A., Röpke, C. & Ødum, Niels, 2002, In: Cytokine. 20, 4, p. 141-7 6 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    14. Published

      Spontaneous interleukin-5 production in cutaneous T-cell lymphoma lines is mediated by constitutively activated Stat3

      Nielsen, M., Nissen, Mogens Holst, Gerwien, J., Zocca, M., Rasmussen, H. M., Nakajima, K., Röpke, C., Geisler, Carsten, Kaltoft, K. & Ødum, Niels, 2002, In: Blood. 99, 3, p. 973-7 4 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    15. Published

      The CD3 gamma leucine-based receptor-sorting motif is required for efficient ligand-mediated TCR down-regulation

      von Essen, Marina Rode, Bonefeld, Charlotte Menne, Nielsen, B. L., Lauritsen, J. P. H., Dietrich, J., Andersen, P. S., Karjalainen, K., Ødum, Niels & Geisler, Carsten, 2002, In: Journal of Immunology. 168, 9, p. 4519-23 4 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    16. 2003
    17. Published

      Bi-phasic effect of interferon (IFN)-alpha: IFN-alpha up- and down-regulates interleukin-4 signaling in human T cells

      Eriksen, K. W., Sommer, V. H., Woetmann, Anders , Rasmussen, A. B., Brender, C., Svejgaard, A., Skov, Søren, Geisler, Carsten & Ødum, Niels, 2003, In: Journal of Biological Chemistry. 279, 1, p. 169-76 7 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    18. Published

      Constitutive STAT3 activation in intestinal T cells from patients with Crohn's disease

      Lovato, P., Brender, C., Agnholt, J., Kelsen, J., Kaltoft, K., Svejgaard, A., Eriksen, K. W., Woetmann, Anders & Ødum, Niels, 2003, In: Journal of Biological Chemistry. 278, 19, p. 16777-81 4 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    19. Published

      Histone deacetylase inhibitors: a new class of immunosuppressors targeting a novel signal pathway essential for CD154 expression

      Skov, Søren, Rieneck, K., Bovin, L. F., Skak, K., Tomra, S., Michelsen, B. K. & Ødum, Niels, 2003, In: Blood. 101(4), p. 1430-1438

      Research output: Contribution to journal › Journal article › Research › peer-review

    20. Published

      Protein phosphates 2A (PP2A) regulates IL-4- mediated STAT6 signalling

      Woetmann, Anders , Nielsen, M., Brockdorff, J., Leick, V., Rieneck, K., Bendtzen, K., Geisler, C. & Ødum, Niels, 2003, In: Journal of Biological Chemistry. 278, p. 2787-2791

      Research output: Contribution to journal › Journal article › Research › peer-review

    21. Published

      TCR comodulation of nonengaged TCR takes place by a protein kinase C and CD3 gamma di-leucine-based motif-dependent mechanism

      Bonefeld, Charlotte Menne, Rasmussen, B. A., Lauritsen, J. P., von Essen, Marina Rode, Ødum, Niels, Andersen, P. S. & Geisler, Carsten, 2003, In: Journal of Immunology. 171, 6, p. 3003-9 6 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    22. 2004
    23. Published

      In vivo activation of STAT3 in cutaneous T-cell lymphoma. Evidence for an antiapoptotic function of STAT3.

      Sommer, V. H., Clemmensen, O. J., Nielsen, O., Wasik, M., Lovato, P., Brender, C., Eriksen, K. W., Woetmann, Anders , Kaestel, C. G., Nissen, Mogens Holst, Ropke, C., Skov, Søren & Ødum, Niels, 2004, In: Leukemia. 18, 7, p. 1288-95 7 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    24. Published

      Masking of the CD3 gamma di-leucine-based motif by zeta is required for efficient T-cell receptor expression

      Lauritsen, J. P. H., Bonefeld, Charlotte Menne, von Essen, Marina Rode, Nielsen, M. W., Rasmussen, A. B., Ødum, Niels, Dietrich, J. & Geisler, Carsten, 2004, In: Traffic - International Journal of Intracellular Transport. 5, 9, p. 672-84 12 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    25. Published

      Proteasomal targeting and minigene repetition improve cell-surface presentation of a transfected, modified melanoma tumour antigen

      Rasmussen, A. B., Zocca, M., Bonefeld, Charlotte Menne, von Essen, Marina Rode, Lauritsen, J. P., Tomra, S., Ødum, Niels & Geisler, Carsten, 2004, In: Scandinavian Journal of Immunology. 59, 2, p. 220-7 7 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    26. Published

      SOCS5 is expressed in primary B and T lymphoid cells but is dispensable for lymphocyte production and function

      Brender, C., Columbus, R., Metcalf, D., Handman, E., Starr, R., Huntington, N., Tarlinton, D., Ødum, Niels, Nicholson, S. E., Nicola, N. A., Hilton, D. J. & Alexander, W. S., 2004, In: Molecular and Cellular Biology. 24, 13, p. 6094-103 9 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    27. 2005
    28. Published

      A functional polymorphism in the Eta-1 promoter is associated with allele specific binding to the transcription factor Sp1 and elevated gene expression

      Hummelshoj, T., Ryder, L. P., Madsen, H. O., Ødum, Niels & Svejgaard, A., 2005, In: Molecular Immunology. 43, 7, p. 980-6 6 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    29. Published

      Cancer cells become susceptible to natural killer cell killing after exposure to histone deacetylase inhibitors due to glycogen synthase kinase-3-dependent expression of MHC class I-related chain A and B

      Skov, Søren, Pedersen, M. T., Andresen, Lars, Straten, P. T., Woetmann, Anders & Ødum, Niels, 2005, In: Cancer Research. 65, 23, p. 11136-45 9 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    30. Published

      Constitutive SOCS-3 expression protects T-cell lymphoma against growth inhibition by IFNalpha

      Brender, C., Lovato, P., Sommer, V. H., Woetmann, Anders , Mathiesen, A., Geisler, Carsten, Wasik, M. & Ødum, Niels, 2005, In: Leukemia. 19, 2, p. 209-13 4 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    31. Published

      Increased sensitivity to interferon-alpha in psoriatic T cells

      Eriksen, K. W., Lovato, P., Skov, Lone, Krejsgaard, T., Kaltoft, K., Geisler, Carsten & Ødum, Niels, 2005, In: Journal of Investigative Dermatology. 125, 5, p. 936-44 8 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    32. Published

      Inhibition of ALK enzymatic activity in T-cell lymphoma cells induces apoptosis and suppresses proliferation and STAT3 phosphorylation independently of Jak3

      Marzec, Michal Tomasz, Kasprzycka, M., Ptasznik, A., Wlodarski, P., Zhang, Q., Ødum, Niels & Wasik, M. A., 2005, In: Laboratory Investigation. 85, 12, p. 1544-54 10 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    33. Published

      The immune privilege of the eye: human retinal pigment epithelial cells selectively modulate T-cell activation in vitro.

      Kaestel, C. G., Lovato, P., Ødum, Niels, Nissen, Mogens Holst & Röpke, C., 2005, In: Current Eye Research. 30, 5, p. 375-83 8 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    34. 2006
    35. Published

      Jak3- and JNK-dependent vascular endothelial growth factor expression in cutaneous T-cell lymphoma

      Krejsgaard, T., Vetter-Kauczok, C. S., Woetmann, Anders , Lovato, P., Labuda, T., Eriksen, K. W., Zhang, Q., Becker, J. C. & Ødum, Niels, 2006, In: Leukemia. 20, 10, p. 1759-66 7 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    36. Published

      Multi-gene epigenetic silencing of tumor suppressor genes in T-cell lymphoma cells; delayed expression of the p16 protein upon reversal of the silencing

      Nagasawa, T., Zhang, Q., Raghunath, P. N., Wong, H. Y., El-Salem, M., Szallasi, A., Marzec, Michal Tomasz, Gimotty, P., Rook, A. H., Vonderheid, E. C., Ødum, Niels & Wasik, M. A., 2006, In: Leukemia research : a Forum for Studies on Leukemia and Normal Hemopoiesis. 30, 3, p. 303-12 9 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    37. Published

      STAT3 induces transcription of the DNA methyltransferase 1 gene (DNMT1) in malignant T lymphocytes

      Zhang, Q., Wang, H. Y., Woetmann, Anders , Raghunath, P. N., Ødum, Niels & Wasik, M. A., 2006, In: Blood. 108, 3, p. 1058-64 6 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    38. Published

      Spironolactone induces apoptosis and inhibits NF-kappaB independent of the mineralocorticoid receptor

      Sønder, S. U. S., Woetmann, Anders , Ødum, Niels & Bendtzen, K., 2006, In: Apoptosis. 11, 12, p. 2159-65 7 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    39. 2007
    40. Published

      FOXP3+ regulatory T cells in cutaneous T-cell lymphomas: association with disease stage and survival

      Gjerdrum, L. M., Woetmann, Anders , Ødum, Niels, Burton, C. M., Rossen, K., Skovgaard, G. L., Ryder, L. P. & Ralfkiaer, E., 2007, In: Leukemia. 21, 12, p. 2512-2518 6 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    41. Published

      Interleukin 21 therapy increases the density of tumor infiltrating CD8+ T cells and inhibits the growth of syngeneic tumors

      Søndergaard, H., Frederiksen, K. S., Thygesen, P., Galsgaard, E. D., Skak, K., Kristjansen, P. E. G., Ødum, Niels & Kragh, M., 2007, In: Cancer Immunology, Immunotherapy. 56, 9, p. 1417-28 11 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    42. Published

      Loss of SHP-1 tyrosine phosphatase expression correlates with the advanced stages of cutaneous T-cell lymphoma

      Witkiewicz, A., Raghunath, P., Wasik, A., Junkins-Hopkins, J. M., Jones, D., Zhang, Q., Ødum, Niels & Wasik, M. A., 2007, In: Human Pathology. 38, 3, p. 462-7 5 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    43. Published

      Nonmalignant T cells stimulate growth of T-cell lymphoma cells in the presence of bacterial toxins

      Woetmann, Anders , Lovato, P., Eriksen, K. W., Krejsgaard, T., Labuda, T., Zhang, Q., Mathiesen, A., Geisler, Carsten, Svejgaard, A., Wasik, M. A. & Ødum, Niels, 2007, In: Blood. 109, 8, p. 3325-32 7 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    44. 2008
    45. Published

      Differential Effects of Interleukin-2 and Interleukin-15 versus Interleukin-21 on CD4+ Cutaneous T-Cell Lymphoma Cells

      Marzec, Michal Tomasz, Halasa, K., Kasprzycka, M., Wysocka, M., Liu, X., Tobias, J. W., Baldwin, D., Zhang, Q., Ødum, Niels, Rook, A. H. & Wasik, M. A., 2008, In: Cancer Research. 68, 4, p. 1083-91 8 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    46. Published

      EGFR induces expression of IRF-1 via STAT1 and STAT3 activation leading to growth arrest of human cancer cells

      Andersen, P., Pedersen, M. W., Woetmann, Anders , Villingshøj, M., Stockhausen, M., Ødum, Niels & Poulsen, H. S., 2008, In: International Journal of Cancer. 122, 2, p. 342-9 7 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    47. Published

      FOXP3 positive regulatory T-cells in cutaneous T-cell lymphomas

      Gjerdrum, L. M., Woetmann, Anders , Ødum, Niels & Ralfkiaer, E., 2008, In: Virchows Archiv. 452, Suppl. 1, p. S4-S4

      Research output: Contribution to journal › Journal article › Research › peer-review

    48. Published

      FOXP3 positive regulatory T-cells in cutaneous and systemic CD30 positive T-cell lymphoproliferations

      Gjerdrum, L. M., Woetmann, Anders , Ødum, Niels, Hother, C., Henrik-Nielsen, R., Gniadecki, R. & Ralfkiaer, E., 2008, In: European Journal of Haematology. 80, 6, p. 483-9 6 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    49. Published

      Gamma c-signaling cytokines induce a regulatory T cell phenotype in malignant CD4+ T lymphocytes

      Kasprzycka, M., Zhang, Q., Witkiewicz, A., Marzec, M., Potoczek, M., Liu, X., Wang, H. Y., Milone, M., Basu, S., Mauger, J., Choi, J. K., Abrams, J. T., Hou, J. S., Rook, A. H., Vonderheid, E., Woetmann, Anders , Ødum, Niels & Wasik, M. A., 2008, In: Journal of Immunology. 181, 4, p. 2506-12 6 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    50. Published

      IL-2- and IL-15-induced activation of the rapamycin-sensitive mTORC1 pathway in malignant CD4+ T lymphocytes

      Marzec, Michal Tomasz, Liu, X., Kasprzycka, M., Witkiewicz, A., Raghunath, P. N., El-Salem, M., Robertson, E., Ødum, Niels & Wasik, M. A., 2008, In: Blood. 111, 4, p. 2181-9 8 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    51. Published

      Malignant Tregs express low molecular splice forms of FOXP3 in Sézary syndrome

      Krejsgaard, T., Gjerdrum, L. M., Ralfkiaer, E., Lauenborg, B., Eriksen, K. W., Mathiesen, A., Bovin, L. F., Gniadecki, R., Geisler, Carsten, Ryder, L. P., Zhang, Q., Wasik, M. A., Ødum, Niels & Woetmann, Anders , 2008, In: Leukemia. p. 2230-2239 9 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    52. Published

      γc-Signaling Cytokines Induce a Regulatory T Cell Phenotype in Malignant CD4+ T Lymphocytes.

      Kasprzycka, M., Zhang, Q., Witkiewicz, A., Marzec, Michal Tomasz, Potoczek, M., Liu, X., Wang, H. Y., Milone, M., Basu, S., Mauger, J., Choi, J. K., Abrams, J. T., Hou, J. S., Rook, A. H., Vonderheid, E., Woetmann, A., Ødum, Niels & Wasik, M. A., 2008, In: Journal of Immunology. 181, 4, p. 2506-2512 7 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    53. Published

      gamma c-signaling cytokines induce a regulatory T cell phenotype in malignant CD4(+) T lymphocytes

      Kasprzycka, M., Zhang, Q., Witkiewicz, A., Marzec, Michal Tomasz, Potoczek, M., Liu, X., Wang, H. Y., Milone, M., Basu, S., Mauger, J., Choi, J. K., Abrams, J. T., Hou, J. S., Rook, A. H., Vonderheid, E., Woetmann, A., Ødum, Niels & Wasik, M. A., 15 Aug 2008, In: Journal of Immunology. 181, 4, p. 2506-2512

      Research output: Contribution to journal › Journal article › Research › peer-review

    54. 2009
    55. Published

      Ectopic expression of B-lymphoid kinase in cutaneous T-cell lymphoma

      Krejsgaard, T., Vetter-Kauczok, C. S., Woetmann, Anders , Kneitz, H., Eriksen, K. W., Lovato, P., Zhang, Q., Wasik, M. A., Geisler, Carsten, Ralfkiaer, E., Becker, J. C. & Ødum, Niels, 2009, In: Blood. 113, 23, p. 5896-904 8 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    56. Published

      TCR down-regulation controls T cell homeostasis

      Boding, L., Bonefeld, Charlotte Menne, Nielsen, B. L., Lauritsen, J. P. H., von Essen, Marina Rode, Hansen, A. K., Larsen, J. M., Nielsen, M. M., Ødum, Niels & Geisler, Carsten, 2009, In: Journal of Immunology. 183, 8, p. 4994-5005 11 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    57. Published

      TCR down-regulation controls virus-specific CD8+ T cell responses

      Bonefeld, Charlotte Menne, Haks, M., Nielsen, B., von Essen, Marina Rode, Boding, L., Hansen, A. K., Larsen, J. M., Ødum, Niels, Krimpenfort, P., Kruisbeek, A., Christensen, Jan Pravsgaard, Thomsen, Allan Randrup & Geisler, Carsten, 1 Dec 2009, In: Journal of Immunology. 181, 11, p. 7786-7799 14 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    58. 2010
    59. Published

      A novel xenograft model of cutaneous T-cell lymphoma

      Krejsgaard, T., Kopp, K., Ralfkiaer, E., Willumsgaard, A. E., Eriksen, K. W., Labuda, T., Rasmussen, S., Mathiesen, A., Geisler, Carsten, Lauenborg, B., Becker, J. C., Zhang, Q., Wasik, M. A., Ødum, Niels & Woetmann, Anders , 2010, In: Experimental Dermatology. 19, 12, p. 1096-102 7 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    60. Published

      COX-2-dependent PGE2 acts as a growth factor in mycosis fungoides (MF)

      Kopp, K. L. M., Kauczok, C. S., Lauenborg, B. T., Krejsgaard, T. F., Eriksen, K. W. K., Zhang, Q., Wasik, M. A., Geisler, Carsten, Ralfkiaer, E. M., Becker, J. C., Ødum, Niels & Woetmann, Anders , 2010, In: Leukemia. 24, 6, p. 1179-1185 7 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

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