Niels Ødum
Professor
Skin Immunology Research Center
Blegdamsvej 3B, 2200 København N, 07 Bygning 7, Building: 07-12-86
Member of:
- 2001
- Published
Oligonucleotide fishing for STAT6: cross-talk between IL-4 and chemokines.
Eriksen, K. W., Nielsen, M., Kaltoft, K., Svejgaard, A., Nissen, Mogens Holst, Röpke, C. & Ødum, Niels, 2001, In: Experimental and Clinical Immunogenetics. 18, 4, p. 233-41 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Radically altered T cell receptor signaling in glycopeptide-specific T cell hybridoma induced by antigen with minimal differences in the glycan group
Jensen, T., Nielsen, M., Gad, M., Hansen, P., Komba, S., Meldal, M., Ødum, Niels & Werdelin, O., 2001, In: European Journal of Immunology. 31, 11, p. 3197-206 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
STAT3-mediated constitutive expression of SOCS-3 in cutaneous T-cell lymphoma
Brender, C., Nielsen, M., Kaltoft, K., Mikkelsen, G., Zhang, Q., Wasik, M., Billestrup, N. & Ødum, Niels, 2001, In: Blood. 97, 4, p. 1056-62 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Superantigen presentation by human retinal pigment epithelial cells to T cells is dependent on CD2-CD58 and CD18-CD54 molecule interactions.
Jørgensen, A., Junker, N., Kaestel, C. G., Liang, Y., Wiencke, A., la Cour, M., Lui, G. M., Ødum, Niels, Nissen, Mogens Holst & Röpke, C., 2001, In: Experimental Eye Research. 73, 5, p. 723-33 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2002
- Published
Endo- and exocytic rate constants for spontaneous and protein kinase C-activated T cell receptor cycling
Bonefeld, Charlotte Menne, Møller Sørensen, T., Siersma, Volkert Dirk, von Essen, Marina Rode, Ødum, Niels & Geisler, Carsten, 2002, In: European Journal of Immunology. 32, 3, p. 616-26 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Human retinal pigment epithelial cells inhibit proliferation and IL2R expression of activated T cells.
Kaestel, C. G., Jørgensen, A., Nielsen, M., Eriksen, K. W., Ødum, Niels, Nissen, Mogens Holst & Röpke, C., 2002, In: Experimental Eye Research. 74, 5, p. 627-37 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
IL-15 induces unspecific effector functions in human peptide-specific CD8+ T-cell cultures.
Lyngstrand, S. T., Würtzen, P. A., Ødum, Niels, Nissen, Mogens Holst & Röpke, C., 2002, In: Scandinavian Journal of Immunology. 56, 6, p. 602-10 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Ligand-induced TCR down-regulation is not dependent on constitutive TCR cycling
Dietrich, J., Bonefeld, Charlotte Menne, Lauritsen, J. P. H., von Essen, Marina Rode, Rasmussen, B. A., Ødum, Niels & Geisler, Carsten, 2002, In: Journal of Immunology. 168, 11, p. 5434-40 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Multilevel dysregulation of STAT3 activation in anaplastic lymphoma kinase-positive T/null-cell lymphoma
Zhang, Q., Raghunath, P. N., Xue, L., Majewski, M., Carpentieri, D. F., Ødum, Niels, Morris, S., Skorski, T. & Wasik, M. A., 2002, In: Journal of Immunology. 168, 1, p. 466-74 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Protein phosphatase 2A (PP2A) regulates interleukin-4-mediated STAT6 signaling
Woetmann, Anders , Brockdorff, J., Lovato, P., Nielsen, M., Leick, V., Rieneck, K., Svejgaard, A., Geisler, Carsten & Ødum, Niels, 2002, In: Journal of Biological Chemistry. 278, 5, p. 2787-91 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
SHP2 regulates IL-2 induced MAPK activation, but not Stat3 or Stat5 tyrosine phosphorylation, in cutaneous T cell lymphoma cells
Lundin Brockdorff, J., Woetmann, Anders , Mustelin, T., Kaltoft, K., Zhang, Q., Wasik, M. A., Röpke, C. & Ødum, Niels, 2002, In: Cytokine. 20, 4, p. 141-7 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Spontaneous interleukin-5 production in cutaneous T-cell lymphoma lines is mediated by constitutively activated Stat3
Nielsen, M., Nissen, Mogens Holst, Gerwien, J., Zocca, M., Rasmussen, H. M., Nakajima, K., Röpke, C., Geisler, Carsten, Kaltoft, K. & Ødum, Niels, 2002, In: Blood. 99, 3, p. 973-7 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The CD3 gamma leucine-based receptor-sorting motif is required for efficient ligand-mediated TCR down-regulation
von Essen, Marina Rode, Bonefeld, Charlotte Menne, Nielsen, B. L., Lauritsen, J. P. H., Dietrich, J., Andersen, P. S., Karjalainen, K., Ødum, Niels & Geisler, Carsten, 2002, In: Journal of Immunology. 168, 9, p. 4519-23 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2003
- Published
Bi-phasic effect of interferon (IFN)-alpha: IFN-alpha up- and down-regulates interleukin-4 signaling in human T cells
Eriksen, K. W., Sommer, V. H., Woetmann, Anders , Rasmussen, A. B., Brender, C., Svejgaard, A., Skov, Søren, Geisler, Carsten & Ødum, Niels, 2003, In: Journal of Biological Chemistry. 279, 1, p. 169-76 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Constitutive STAT3 activation in intestinal T cells from patients with Crohn's disease
Lovato, P., Brender, C., Agnholt, J., Kelsen, J., Kaltoft, K., Svejgaard, A., Eriksen, K. W., Woetmann, Anders & Ødum, Niels, 2003, In: Journal of Biological Chemistry. 278, 19, p. 16777-81 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Histone deacetylase inhibitors: a new class of immunosuppressors targeting a novel signal pathway essential for CD154 expression
Skov, Søren, Rieneck, K., Bovin, L. F., Skak, K., Tomra, S., Michelsen, B. K. & Ødum, Niels, 2003, In: Blood. 101(4), p. 1430-1438Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Protein phosphates 2A (PP2A) regulates IL-4- mediated STAT6 signalling
Woetmann, Anders , Nielsen, M., Brockdorff, J., Leick, V., Rieneck, K., Bendtzen, K., Geisler, C. & Ødum, Niels, 2003, In: Journal of Biological Chemistry. 278, p. 2787-2791Research output: Contribution to journal › Journal article › Research › peer-review
- Published
TCR comodulation of nonengaged TCR takes place by a protein kinase C and CD3 gamma di-leucine-based motif-dependent mechanism
Bonefeld, Charlotte Menne, Rasmussen, B. A., Lauritsen, J. P., von Essen, Marina Rode, Ødum, Niels, Andersen, P. S. & Geisler, Carsten, 2003, In: Journal of Immunology. 171, 6, p. 3003-9 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2004
- Published
In vivo activation of STAT3 in cutaneous T-cell lymphoma. Evidence for an antiapoptotic function of STAT3.
Sommer, V. H., Clemmensen, O. J., Nielsen, O., Wasik, M., Lovato, P., Brender, C., Eriksen, K. W., Woetmann, Anders , Kaestel, C. G., Nissen, Mogens Holst, Ropke, C., Skov, Søren & Ødum, Niels, 2004, In: Leukemia. 18, 7, p. 1288-95 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Masking of the CD3 gamma di-leucine-based motif by zeta is required for efficient T-cell receptor expression
Lauritsen, J. P. H., Bonefeld, Charlotte Menne, von Essen, Marina Rode, Nielsen, M. W., Rasmussen, A. B., Ødum, Niels, Dietrich, J. & Geisler, Carsten, 2004, In: Traffic - International Journal of Intracellular Transport. 5, 9, p. 672-84 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Proteasomal targeting and minigene repetition improve cell-surface presentation of a transfected, modified melanoma tumour antigen
Rasmussen, A. B., Zocca, M., Bonefeld, Charlotte Menne, von Essen, Marina Rode, Lauritsen, J. P., Tomra, S., Ødum, Niels & Geisler, Carsten, 2004, In: Scandinavian Journal of Immunology. 59, 2, p. 220-7 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
SOCS5 is expressed in primary B and T lymphoid cells but is dispensable for lymphocyte production and function
Brender, C., Columbus, R., Metcalf, D., Handman, E., Starr, R., Huntington, N., Tarlinton, D., Ødum, Niels, Nicholson, S. E., Nicola, N. A., Hilton, D. J. & Alexander, W. S., 2004, In: Molecular and Cellular Biology. 24, 13, p. 6094-103 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2005
- Published
A functional polymorphism in the Eta-1 promoter is associated with allele specific binding to the transcription factor Sp1 and elevated gene expression
Hummelshoj, T., Ryder, L. P., Madsen, H. O., Ødum, Niels & Svejgaard, A., 2005, In: Molecular Immunology. 43, 7, p. 980-6 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Cancer cells become susceptible to natural killer cell killing after exposure to histone deacetylase inhibitors due to glycogen synthase kinase-3-dependent expression of MHC class I-related chain A and B
Skov, Søren, Pedersen, M. T., Andresen, Lars, Straten, P. T., Woetmann, Anders & Ødum, Niels, 2005, In: Cancer Research. 65, 23, p. 11136-45 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Constitutive SOCS-3 expression protects T-cell lymphoma against growth inhibition by IFNalpha
Brender, C., Lovato, P., Sommer, V. H., Woetmann, Anders , Mathiesen, A., Geisler, Carsten, Wasik, M. & Ødum, Niels, 2005, In: Leukemia. 19, 2, p. 209-13 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Increased sensitivity to interferon-alpha in psoriatic T cells
Eriksen, K. W., Lovato, P., Skov, Lone, Krejsgaard, T., Kaltoft, K., Geisler, Carsten & Ødum, Niels, 2005, In: Journal of Investigative Dermatology. 125, 5, p. 936-44 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Inhibition of ALK enzymatic activity in T-cell lymphoma cells induces apoptosis and suppresses proliferation and STAT3 phosphorylation independently of Jak3
Marzec, Michal Tomasz, Kasprzycka, M., Ptasznik, A., Wlodarski, P., Zhang, Q., Ødum, Niels & Wasik, M. A., 2005, In: Laboratory Investigation. 85, 12, p. 1544-54 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The immune privilege of the eye: human retinal pigment epithelial cells selectively modulate T-cell activation in vitro.
Kaestel, C. G., Lovato, P., Ødum, Niels, Nissen, Mogens Holst & Röpke, C., 2005, In: Current Eye Research. 30, 5, p. 375-83 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2006
- Published
Jak3- and JNK-dependent vascular endothelial growth factor expression in cutaneous T-cell lymphoma
Krejsgaard, T., Vetter-Kauczok, C. S., Woetmann, Anders , Lovato, P., Labuda, T., Eriksen, K. W., Zhang, Q., Becker, J. C. & Ødum, Niels, 2006, In: Leukemia. 20, 10, p. 1759-66 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Multi-gene epigenetic silencing of tumor suppressor genes in T-cell lymphoma cells; delayed expression of the p16 protein upon reversal of the silencing
Nagasawa, T., Zhang, Q., Raghunath, P. N., Wong, H. Y., El-Salem, M., Szallasi, A., Marzec, Michal Tomasz, Gimotty, P., Rook, A. H., Vonderheid, E. C., Ødum, Niels & Wasik, M. A., 2006, In: Leukemia research : a Forum for Studies on Leukemia and Normal Hemopoiesis. 30, 3, p. 303-12 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
STAT3 induces transcription of the DNA methyltransferase 1 gene (DNMT1) in malignant T lymphocytes
Zhang, Q., Wang, H. Y., Woetmann, Anders , Raghunath, P. N., Ødum, Niels & Wasik, M. A., 2006, In: Blood. 108, 3, p. 1058-64 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Spironolactone induces apoptosis and inhibits NF-kappaB independent of the mineralocorticoid receptor
Sønder, S. U. S., Woetmann, Anders , Ødum, Niels & Bendtzen, K., 2006, In: Apoptosis. 11, 12, p. 2159-65 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2007
- Published
FOXP3+ regulatory T cells in cutaneous T-cell lymphomas: association with disease stage and survival
Gjerdrum, L. M., Woetmann, Anders , Ødum, Niels, Burton, C. M., Rossen, K., Skovgaard, G. L., Ryder, L. P. & Ralfkiaer, E., 2007, In: Leukemia. 21, 12, p. 2512-2518 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Interleukin 21 therapy increases the density of tumor infiltrating CD8+ T cells and inhibits the growth of syngeneic tumors
Søndergaard, H., Frederiksen, K. S., Thygesen, P., Galsgaard, E. D., Skak, K., Kristjansen, P. E. G., Ødum, Niels & Kragh, M., 2007, In: Cancer Immunology, Immunotherapy. 56, 9, p. 1417-28 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Loss of SHP-1 tyrosine phosphatase expression correlates with the advanced stages of cutaneous T-cell lymphoma
Witkiewicz, A., Raghunath, P., Wasik, A., Junkins-Hopkins, J. M., Jones, D., Zhang, Q., Ødum, Niels & Wasik, M. A., 2007, In: Human Pathology. 38, 3, p. 462-7 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Nonmalignant T cells stimulate growth of T-cell lymphoma cells in the presence of bacterial toxins
Woetmann, Anders , Lovato, P., Eriksen, K. W., Krejsgaard, T., Labuda, T., Zhang, Q., Mathiesen, A., Geisler, Carsten, Svejgaard, A., Wasik, M. A. & Ødum, Niels, 2007, In: Blood. 109, 8, p. 3325-32 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2008
- Published
Differential Effects of Interleukin-2 and Interleukin-15 versus Interleukin-21 on CD4+ Cutaneous T-Cell Lymphoma Cells
Marzec, Michal Tomasz, Halasa, K., Kasprzycka, M., Wysocka, M., Liu, X., Tobias, J. W., Baldwin, D., Zhang, Q., Ødum, Niels, Rook, A. H. & Wasik, M. A., 2008, In: Cancer Research. 68, 4, p. 1083-91 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
EGFR induces expression of IRF-1 via STAT1 and STAT3 activation leading to growth arrest of human cancer cells
Andersen, P., Pedersen, M. W., Woetmann, Anders , Villingshøj, M., Stockhausen, M., Ødum, Niels & Poulsen, H. S., 2008, In: International Journal of Cancer. 122, 2, p. 342-9 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
FOXP3 positive regulatory T-cells in cutaneous T-cell lymphomas
Gjerdrum, L. M., Woetmann, Anders , Ødum, Niels & Ralfkiaer, E., 2008, In: Virchows Archiv. 452, Suppl. 1, p. S4-S4Research output: Contribution to journal › Journal article › Research › peer-review
- Published
FOXP3 positive regulatory T-cells in cutaneous and systemic CD30 positive T-cell lymphoproliferations
Gjerdrum, L. M., Woetmann, Anders , Ødum, Niels, Hother, C., Henrik-Nielsen, R., Gniadecki, R. & Ralfkiaer, E., 2008, In: European Journal of Haematology. 80, 6, p. 483-9 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Gamma c-signaling cytokines induce a regulatory T cell phenotype in malignant CD4+ T lymphocytes
Kasprzycka, M., Zhang, Q., Witkiewicz, A., Marzec, M., Potoczek, M., Liu, X., Wang, H. Y., Milone, M., Basu, S., Mauger, J., Choi, J. K., Abrams, J. T., Hou, J. S., Rook, A. H., Vonderheid, E., Woetmann, Anders , Ødum, Niels & Wasik, M. A., 2008, In: Journal of Immunology. 181, 4, p. 2506-12 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
IL-2- and IL-15-induced activation of the rapamycin-sensitive mTORC1 pathway in malignant CD4+ T lymphocytes
Marzec, Michal Tomasz, Liu, X., Kasprzycka, M., Witkiewicz, A., Raghunath, P. N., El-Salem, M., Robertson, E., Ødum, Niels & Wasik, M. A., 2008, In: Blood. 111, 4, p. 2181-9 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Malignant Tregs express low molecular splice forms of FOXP3 in Sézary syndrome
Krejsgaard, T., Gjerdrum, L. M., Ralfkiaer, E., Lauenborg, B., Eriksen, K. W., Mathiesen, A., Bovin, L. F., Gniadecki, R., Geisler, Carsten, Ryder, L. P., Zhang, Q., Wasik, M. A., Ødum, Niels & Woetmann, Anders , 2008, In: Leukemia. p. 2230-2239 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
γc-Signaling Cytokines Induce a Regulatory T Cell Phenotype in Malignant CD4+ T Lymphocytes.
Kasprzycka, M., Zhang, Q., Witkiewicz, A., Marzec, Michal Tomasz, Potoczek, M., Liu, X., Wang, H. Y., Milone, M., Basu, S., Mauger, J., Choi, J. K., Abrams, J. T., Hou, J. S., Rook, A. H., Vonderheid, E., Woetmann, A., Ødum, Niels & Wasik, M. A., 2008, In: Journal of Immunology. 181, 4, p. 2506-2512 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
gamma c-signaling cytokines induce a regulatory T cell phenotype in malignant CD4(+) T lymphocytes
Kasprzycka, M., Zhang, Q., Witkiewicz, A., Marzec, Michal Tomasz, Potoczek, M., Liu, X., Wang, H. Y., Milone, M., Basu, S., Mauger, J., Choi, J. K., Abrams, J. T., Hou, J. S., Rook, A. H., Vonderheid, E., Woetmann, A., Ødum, Niels & Wasik, M. A., 15 Aug 2008, In: Journal of Immunology. 181, 4, p. 2506-2512Research output: Contribution to journal › Journal article › Research › peer-review
- 2009
- Published
Ectopic expression of B-lymphoid kinase in cutaneous T-cell lymphoma
Krejsgaard, T., Vetter-Kauczok, C. S., Woetmann, Anders , Kneitz, H., Eriksen, K. W., Lovato, P., Zhang, Q., Wasik, M. A., Geisler, Carsten, Ralfkiaer, E., Becker, J. C. & Ødum, Niels, 2009, In: Blood. 113, 23, p. 5896-904 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
TCR down-regulation controls T cell homeostasis
Boding, L., Bonefeld, Charlotte Menne, Nielsen, B. L., Lauritsen, J. P. H., von Essen, Marina Rode, Hansen, A. K., Larsen, J. M., Nielsen, M. M., Ødum, Niels & Geisler, Carsten, 2009, In: Journal of Immunology. 183, 8, p. 4994-5005 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
TCR down-regulation controls virus-specific CD8+ T cell responses
Bonefeld, Charlotte Menne, Haks, M., Nielsen, B., von Essen, Marina Rode, Boding, L., Hansen, A. K., Larsen, J. M., Ødum, Niels, Krimpenfort, P., Kruisbeek, A., Christensen, Jan Pravsgaard, Thomsen, Allan Randrup & Geisler, Carsten, 1 Dec 2009, In: Journal of Immunology. 181, 11, p. 7786-7799 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2010
- Published
A novel xenograft model of cutaneous T-cell lymphoma
Krejsgaard, T., Kopp, K., Ralfkiaer, E., Willumsgaard, A. E., Eriksen, K. W., Labuda, T., Rasmussen, S., Mathiesen, A., Geisler, Carsten, Lauenborg, B., Becker, J. C., Zhang, Q., Wasik, M. A., Ødum, Niels & Woetmann, Anders , 2010, In: Experimental Dermatology. 19, 12, p. 1096-102 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
COX-2-dependent PGE2 acts as a growth factor in mycosis fungoides (MF)
Kopp, K. L. M., Kauczok, C. S., Lauenborg, B. T., Krejsgaard, T. F., Eriksen, K. W. K., Zhang, Q., Wasik, M. A., Geisler, Carsten, Ralfkiaer, E. M., Becker, J. C., Ødum, Niels & Woetmann, Anders , 2010, In: Leukemia. 24, 6, p. 1179-1185 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
ID: 14062
Most downloads
-
2069
downloads
Vitamin D up-regulates the vitamin D receptor by protecting it from proteasomal degradation in human CD4+ T cells
Research output: Contribution to journal › Journal article › Research › peer-review
Published -
427
downloads
Vitamin D counteracts Mycobacterium tuberculosis-induced cathelicidin downregulation in dendritic cells and allows Th1 differentiation and IFNγ secretion
Research output: Contribution to journal › Journal article › Research › peer-review
Published -
351
downloads
STAT5 induces miR-21 expression in cutaneous T cell lymphoma
Research output: Contribution to journal › Journal article › Research › peer-review
Published