Immune Regulation

The Immune Regulation group investigates how immune cells maintain balance and respond to challenges in barrier tissues such as the skin, gut, and lungs. The group focuses on mechanisms driving immune homeostasis and dysregulation in inflammatory skin diseases, and how microbiota shape immune responses.

Group picture

 

 

 

The immune system plays a vital role in maintaining balance at barrier sites like the skin, gut, and lungs - interfaces where the body interacts with the external environment. When this balance is disrupted, it can lead to chronic inflammatory conditions, including skin diseases like psoriasis and eczema.

Our research focuses on understanding how immune homeostasis is maintained and what triggers immune dysregulation in barrier tissues. We study how microbiota and their metabolites influence immune responses and explore how immune cells adapt during inflammation and disease. Using patient samples, preclinical models, and cutting-edge technologies like single-cell RNA sequencing and proteomics, we aim to uncover the mechanisms driving chronic inflammation and immune dysfunction.

We also investigate therapeutic strategies such as mesenchymal stem cell (MSC) therapy and identify immune pathways that may be targeted in diseases like psoriasis, inflammatory bowel disease, and meningiomas. Ultimately, our goal is to contribute to the development of more effective and precise treatments for immune-mediated diseases.

 

Group Leader

Group leaderAnders Woetmann Andersen
Professor

Email

Staff list

Name Title Phone E-mail
Anders Woetmann Andersen Professor +4535327868 E-mail