Arabidopsis MKS1 is involved in basal immunity and requires an intact N-terminal domain for proper function

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Innate immune signaling pathways in animals and plants are regulated by mitogen-activated protein kinase (MAPK) cascades. MAP kinase 4 (MPK4) functions downstream of innate immune receptors via a nuclear substrate MKS1 to regulate the activity of the WRKY33 transcription factor, which in turn controls the production of anti-microbial phytoalexins.
Original languageEnglish
JournalP L o S One
Volume5
Issue number12
Pages (from-to)e14364
ISSN1932-6203
DOIs
Publication statusPublished - 1 Jan 2010

    Research areas

  • Arabidopsis, Arabidopsis Proteins, Genotype, Immune System, MAP Kinase Signaling System, Microscopy, Confocal, Mitogen-Activated Protein Kinases, Mutagenesis, Site-Directed, Mutation, Phenotype, Phosphoproteins, Plant Physiological Phenomena, Plasmids, Protein Structure, Tertiary, Transcription Factors, Two-Hybrid System Techniques

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