Arabidopsis mitogen-activated protein kinase kinases MKK1 and MKK2 have overlapping functions in defense signaling mediated by MEKK1, MPK4, and MKS1.

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Standard

Arabidopsis mitogen-activated protein kinase kinases MKK1 and MKK2 have overlapping functions in defense signaling mediated by MEKK1, MPK4, and MKS1. / Qiu, Jin-Long; Zhou, Lu; Yun, Byung-Wook; Nielsen, Henrik Bjørn; Fiil, Berthe Katrine; Petersen, Klaus; Mackinlay, Jim; Loake, Gary J; Mundy, John; Morris, Peter C.

In: Plant Physiology, Vol. 148, No. 1, 2008, p. 212-22.

Research output: Contribution to journal › Journal article › Research › peer-review

Harvard

Qiu, J-L, Zhou, L, Yun, B-W, Nielsen, HB, Fiil, BK, Petersen, K, Mackinlay, J, Loake, GJ, Mundy, J & Morris, PC 2008, 'Arabidopsis mitogen-activated protein kinase kinases MKK1 and MKK2 have overlapping functions in defense signaling mediated by MEKK1, MPK4, and MKS1.', Plant Physiology, vol. 148, no. 1, pp. 212-22. https://doi.org/10.1104/pp.108.120006

APA

Qiu, J-L., Zhou, L., Yun, B-W., Nielsen, H. B., Fiil, B. K., Petersen, K., Mackinlay, J., Loake, G. J., Mundy, J., & Morris, P. C. (2008). Arabidopsis mitogen-activated protein kinase kinases MKK1 and MKK2 have overlapping functions in defense signaling mediated by MEKK1, MPK4, and MKS1. Plant Physiology, 148(1), 212-22. https://doi.org/10.1104/pp.108.120006

Vancouver

Qiu J-L, Zhou L, Yun B-W, Nielsen HB, Fiil BK, Petersen K et al. Arabidopsis mitogen-activated protein kinase kinases MKK1 and MKK2 have overlapping functions in defense signaling mediated by MEKK1, MPK4, and MKS1. Plant Physiology. 2008;148(1):212-22. https://doi.org/10.1104/pp.108.120006

Author

Qiu, Jin-Long ; Zhou, Lu ; Yun, Byung-Wook ; Nielsen, Henrik Bjørn ; Fiil, Berthe Katrine ; Petersen, Klaus ; Mackinlay, Jim ; Loake, Gary J ; Mundy, John ; Morris, Peter C. / Arabidopsis mitogen-activated protein kinase kinases MKK1 and MKK2 have overlapping functions in defense signaling mediated by MEKK1, MPK4, and MKS1. In: Plant Physiology. 2008 ; Vol. 148, No. 1. pp. 212-22.

Bibtex

@article{d0fcedf0939511dd86a6000ea68e967b,
title = "Arabidopsis mitogen-activated protein kinase kinases MKK1 and MKK2 have overlapping functions in defense signaling mediated by MEKK1, MPK4, and MKS1.",
abstract = "The Arabidopsis (Arabidopsis thaliana) MKK1 and MKK2 mitogen-activated protein kinase kinases have been implicated in biotic and abiotic stress responses as part of a signaling cascade including MEKK1 and MPK4. Here, the double loss-of-function mutant (mkk1/2) of MKK1 and MKK2 is shown to have marked phenotypes in development and disease resistance similar to those of the single mekk1 and mpk4 mutants. Because mkk1 or mkk2 single mutants appear wild type, basal levels of MPK4 activity are not impaired in them, and MKK1 and MKK2 are in part functionally redundant in unchallenged plants. These findings are confirmed and extended by biochemical and molecular analyses implicating the kinases in jasmonate- and salicylate-dependent defense responses, mediated in part via the MPK4 substrate MKS1. In addition, transcriptome analyses delineate overlapping and specific effects of the kinases on global gene expression patterns demonstrating both redundant and unique functions for MKK1 and MKK2.",
author = "Jin-Long Qiu and Lu Zhou and Byung-Wook Yun and Nielsen, {Henrik Bj{\o}rn} and Fiil, {Berthe Katrine} and Klaus Petersen and Jim Mackinlay and Loake, {Gary J} and John Mundy and Morris, {Peter C}",
year = "2008",
doi = "10.1104/pp.108.120006",
language = "English",
volume = "148",
pages = "212--22",
journal = "Plant Physiology",
issn = "0032-0889",
publisher = "American Society of Plant Biologists",
number = "1",

}

RIS

TY - JOUR

T1 - Arabidopsis mitogen-activated protein kinase kinases MKK1 and MKK2 have overlapping functions in defense signaling mediated by MEKK1, MPK4, and MKS1.

AU - Qiu, Jin-Long

AU - Zhou, Lu

AU - Yun, Byung-Wook

AU - Nielsen, Henrik Bjørn

AU - Fiil, Berthe Katrine

AU - Petersen, Klaus

AU - Mackinlay, Jim

AU - Loake, Gary J

AU - Mundy, John

AU - Morris, Peter C

PY - 2008

Y1 - 2008

N2 - The Arabidopsis (Arabidopsis thaliana) MKK1 and MKK2 mitogen-activated protein kinase kinases have been implicated in biotic and abiotic stress responses as part of a signaling cascade including MEKK1 and MPK4. Here, the double loss-of-function mutant (mkk1/2) of MKK1 and MKK2 is shown to have marked phenotypes in development and disease resistance similar to those of the single mekk1 and mpk4 mutants. Because mkk1 or mkk2 single mutants appear wild type, basal levels of MPK4 activity are not impaired in them, and MKK1 and MKK2 are in part functionally redundant in unchallenged plants. These findings are confirmed and extended by biochemical and molecular analyses implicating the kinases in jasmonate- and salicylate-dependent defense responses, mediated in part via the MPK4 substrate MKS1. In addition, transcriptome analyses delineate overlapping and specific effects of the kinases on global gene expression patterns demonstrating both redundant and unique functions for MKK1 and MKK2.

AB - The Arabidopsis (Arabidopsis thaliana) MKK1 and MKK2 mitogen-activated protein kinase kinases have been implicated in biotic and abiotic stress responses as part of a signaling cascade including MEKK1 and MPK4. Here, the double loss-of-function mutant (mkk1/2) of MKK1 and MKK2 is shown to have marked phenotypes in development and disease resistance similar to those of the single mekk1 and mpk4 mutants. Because mkk1 or mkk2 single mutants appear wild type, basal levels of MPK4 activity are not impaired in them, and MKK1 and MKK2 are in part functionally redundant in unchallenged plants. These findings are confirmed and extended by biochemical and molecular analyses implicating the kinases in jasmonate- and salicylate-dependent defense responses, mediated in part via the MPK4 substrate MKS1. In addition, transcriptome analyses delineate overlapping and specific effects of the kinases on global gene expression patterns demonstrating both redundant and unique functions for MKK1 and MKK2.

U2 - 10.1104/pp.108.120006

DO - 10.1104/pp.108.120006

M3 - Journal article

C2 - 18599650

VL - 148

SP - 212

EP - 222

JO - Plant Physiology

JF - Plant Physiology

SN - 0032-0889

IS - 1

ER -

ID: 6446424