Berthe Katrine Fiil

Berthe Katrine Fiil

Tenure Track Assistant Professor


  1. 2022
  2. Published

    Human ZBP1 induces cell death-independent inflammatory signaling via RIPK3 and RIPK1

    Peng, R., Wang, Chris Kedong, Wang-Kan, X., Idorn, M., Kjær, M., Zhou, F. Y., Fiil, Berthe Katrine, Timmermann, F., Orozco, S. L., McCarthy, J., Leung, C. S., Lu, X., Bagola, K., Rehwinkel, J., Oberst, A., Maelfait, J., Paludan, S. R. & Gyrd-Hansen, Mads, 2022, In: EMBO Reports. 2022, 23, e55839.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Orally active bivalent VHH construct prevents proliferation of F4+ enterotoxigenic Escherichia coli in weaned piglets

    Fiil, Berthe Katrine, Thrane, S. W., Pichler, M., Kittilä, T., Ledsgaard, L., Ahmadi, S., Hermansen, G. M. M., Jelsbak, L., Lauridsen, C., Brix, S. & Laustsen, A. H., 2022, In: iScience. 25, 4, 104003.

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. 2021
  5. Published

    The Met1-linked ubiquitin machinery in inflammation and infection

    Fiil, Berthe Katrine & Gyrd-Hansen, Mads, 2021, In: Cell Death and Differentiation. 28, p. 557–569

    Research output: Contribution to journalReviewResearchpeer-review

  6. 2016
  7. SPATA2 Links CYLD to LUBAC, Activates CYLD, and Controls LUBAC Signaling

    Elliott, P. R., Leske, D., Hrdinka, M., Bagola, K., Fiil, Berthe Katrine, McLaughlin, S. H., Wagstaff, J., Volkmar, N., Christianson, J. C., Kessler, B. M., Freund, S. M. V., Komander, D. & Gyrd-Hansen, Mads, 15 Sep 2016, In: Molecular Cell. 63, 6, p. 990-1005 16 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. CYLD Limits Lys63- and Met1-Linked Ubiquitin at Receptor Complexes to Regulate Innate Immune Signaling

    Hrdinka, M., Fiil, Berthe Katrine, Zucca, M., Leske, D., Bagola, K., Yabal, M., Elliott, P. R., Damgaard, R. B., Komander, D., Jost, P. J. & Gyrd-Hansen, Mads, 29 Mar 2016, In: Cell Reports. 14, 12, p. 2846-58 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. 2015
  10. Published

    Symptomatic Males and Female Carriers in a Large Caucasian Kindred with XIAP Deficiency

    Dziadzio, M., Ammann, S., Canning, C., Boyle, F., Hassan, A., Cale, C., Elawad, M., Fiil, Berthe Katrine, Gyrd-Hansen, Mads, Salzer, U., Speckmann, C. & Grimbacher, B., 25 Jul 2015, In: Journal of Clinical Immunology. 35, 5, p. 439-444 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    A RIPK2 inhibitor delays NOD signalling events yet prevents inflammatory cytokine production

    Nachbur, U., Stafford, C. A., Bankovacki, A., Zhan, Y., Lindqvist, L. M., Fiil, B. K., Khakham, Y., Ko, H-J., Sandow, J. J., Falk, H., Holien, J. K., Chau, D., Hildebrand, J., Vince, J. E., Sharp, P. P., Webb, A. I., Jackman, K. A., Mühlen, S., Kennedy, C. L., Lowes, K. N. & 8 others, Murphy, J. M., Gyrd-Hansen, Mads, Parker, M. W., Hartland, E. L., Lew, A. M., Huang, D. C. S., Lessene, G. & Silke, J., 17 Mar 2015, In: Nature Communications. 6, 13 p., 6442.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. 2014
  13. Published

    Met1-linked Ubiquitination in Immune Signalling

    Fiil, Berthe Katrine & Gyrd-Hansen, Mads, Oct 2014, In: F E B S Journal. 81, 19, p. 4337-50 14 p.

    Research output: Contribution to journalReviewResearchpeer-review

  14. Published

    Molecular basis and regulation of OTULIN-LUBAC interaction

    Elliott, P. R., Al-Saoudi, S. V., Marco-Casanova, P., Fiil, Berthe Katrine, Keusekotten, K., Mailand, Niels, Freund, S. M. V., Gyrd-Hansen, Mads & Komander, D., 2014, In: Molecular Cell. 54, 3, p. 335-348 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. 2013
  16. Published

    Disease-causing mutations in the XIAP BIR2 domain impair NOD2-dependent immune signalling

    Damgaard, R. B., Fiil, Berthe Katrine, Speckmann, C., Yabal, M., Stadt, U. Z., Bekker-Jensen, Simon Holst, Jost, P. J., Ehl, S., Mailand, Niels & Gyrd-Hansen, Mads, 1 Jul 2013, In: E M B O Journal. 5, p. 1278-1295 18 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

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