The role of interleukin-1β in the immune response to contact allergens

Research output: Contribution to journal › Review › Research › peer-review

Standard

The role of interleukin-1β in the immune response to contact allergens. / Yeung, Kelvin; Mraz, Veronika; Geisler, Carsten; Skov, Lone; Bonefeld, Charlotte M.

In: Contact Dermatitis, Vol. 85, No. 4, 2021, p. 387-397.

Research output: Contribution to journal › Review › Research › peer-review

Harvard

Yeung, K, Mraz, V, Geisler, C, Skov, L & Bonefeld, CM 2021, 'The role of interleukin-1β in the immune response to contact allergens', Contact Dermatitis, vol. 85, no. 4, pp. 387-397. https://doi.org/10.1111/cod.13955

APA

Yeung, K., Mraz, V., Geisler, C., Skov, L., & Bonefeld, C. M. (2021). The role of interleukin-1β in the immune response to contact allergens. Contact Dermatitis, 85(4), 387-397. https://doi.org/10.1111/cod.13955

Vancouver

Yeung K, Mraz V, Geisler C, Skov L, Bonefeld CM. The role of interleukin-1β in the immune response to contact allergens. Contact Dermatitis. 2021;85(4):387-397. https://doi.org/10.1111/cod.13955

Author

Yeung, Kelvin ; Mraz, Veronika ; Geisler, Carsten ; Skov, Lone ; Bonefeld, Charlotte M. / The role of interleukin-1β in the immune response to contact allergens. In: Contact Dermatitis. 2021 ; Vol. 85, No. 4. pp. 387-397.

Bibtex

@article{2dec420d5b1349c482ebb32452c0d923,
title = "The role of interleukin-1β in the immune response to contact allergens",
abstract = "Interleukin-1β (IL-1β) is an important pro-inflammatory cytokine that has an effect on almost every cell lineage in the body. By blocking IL-1β and investigating the IL-1β signaling pathway, several studies have demonstrated a central role of IL-1β in the response to contact allergens. This review summarizes the current literature regarding the basic immunological mechanisms mediated by IL-1β in the different phases of allergic contact dermatitis (ACD) and highlights potential IL-1β-targeted treatment options, which in the future may be relevant in the treatment of patients with ACD. This review is based primarily on studies using various mouse models and human in vitro studies, since clinical studies on the effect of IL-1β in ACD are lacking.",
keywords = "allergic contact dermatitis, immunology, interleukin-1β, T cells",
author = "Kelvin Yeung and Veronika Mraz and Carsten Geisler and Lone Skov and Bonefeld, {Charlotte M.}",
note = "Publisher Copyright: {\textcopyright} 2021 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd",
year = "2021",
doi = "10.1111/cod.13955",
language = "English",
volume = "85",
pages = "387--397",
journal = "Contact Dermatitis",
issn = "0105-1873",
publisher = "Wiley-Blackwell",
number = "4",

}

RIS

TY - JOUR

T1 - The role of interleukin-1β in the immune response to contact allergens

AU - Yeung, Kelvin

AU - Mraz, Veronika

AU - Geisler, Carsten

AU - Skov, Lone

AU - Bonefeld, Charlotte M.

N1 - Publisher Copyright: © 2021 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd

PY - 2021

Y1 - 2021

N2 - Interleukin-1β (IL-1β) is an important pro-inflammatory cytokine that has an effect on almost every cell lineage in the body. By blocking IL-1β and investigating the IL-1β signaling pathway, several studies have demonstrated a central role of IL-1β in the response to contact allergens. This review summarizes the current literature regarding the basic immunological mechanisms mediated by IL-1β in the different phases of allergic contact dermatitis (ACD) and highlights potential IL-1β-targeted treatment options, which in the future may be relevant in the treatment of patients with ACD. This review is based primarily on studies using various mouse models and human in vitro studies, since clinical studies on the effect of IL-1β in ACD are lacking.

AB - Interleukin-1β (IL-1β) is an important pro-inflammatory cytokine that has an effect on almost every cell lineage in the body. By blocking IL-1β and investigating the IL-1β signaling pathway, several studies have demonstrated a central role of IL-1β in the response to contact allergens. This review summarizes the current literature regarding the basic immunological mechanisms mediated by IL-1β in the different phases of allergic contact dermatitis (ACD) and highlights potential IL-1β-targeted treatment options, which in the future may be relevant in the treatment of patients with ACD. This review is based primarily on studies using various mouse models and human in vitro studies, since clinical studies on the effect of IL-1β in ACD are lacking.

KW - allergic contact dermatitis

KW - immunology

KW - interleukin-1β

KW - T cells

U2 - 10.1111/cod.13955

DO - 10.1111/cod.13955

M3 - Review

C2 - 34324721

AN - SCOPUS:85112049290

VL - 85

SP - 387

EP - 397

JO - Contact Dermatitis

JF - Contact Dermatitis

SN - 0105-1873

IS - 4

ER -

ID: 276272022