Özcan Met

Özcan Met

Visiting associate professor, Gæstelektor

Member of:

    ORCID: 0000-0002-3256-7592

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    1 - 25 out of 78Page size: 25
    1. 2024
    2. Published

      Reduced mitochondrial respiration in peripheral T cells after paediatric heamatopoietic stem cell transplantation

      Mølgaard, K., Kielsen, K., Ifversen, M., Met, Özcan, Svane, Inge Marie & Muller, Klaus, 2024, In: Frontiers in Immunology. 14, 1327977.

      Research output: Contribution to journal › Journal article › Research › peer-review

    3. 2023
    4. Published

       of intact tumor fragments with anti-PD-1 and anti-CTLA-4 influences the expansion and specificity of tumor-infiltrating lymphocytes

      Hulen, T. M., Friese, C., Kristensen, N. P., Granhøj, J. S., Borch, T. H., Peeters, M. J. W., Donia, M., Andersen, Mads Hald, Hadrup, S. R., Svane, Inge Marie & Met, Özcan, 2023, In: Frontiers in Immunology. 14, 15 p., 1180997.

      Research output: Contribution to journal › Journal article › Research › peer-review

    5. Published

      Pre-existing TGF-β-specific T-cell immunity in patients with pancreatic cancer predicts survival after checkpoint inhibitors combined with radiotherapy

      Mortensen, R. E. J., Holmström, M. O., Lisle, T. L., Hasselby, Jane Preuss, Willemoe, G. L., Met, Özcan, Svane, Inge Marie, Johansen, Julia Sidenius, Nielsen, Dorte Lisbet, Chen, I. M. & Andersen, Mads Hald, 2023, In: Journal for ImmunoTherapy of Cancer. 11, 3

      Research output: Contribution to journal › Journal article › Research › peer-review

    6. Published

      Restoring tumor immunogenicity with dendritic cell reprogramming

      Zimmermannova, O., Ferreira, A. G., Ascic, E., Santiago, M. V., Kurochkin, I., Hansen, M., Met, Ö., Caiado, I., Shapiro, I. E., Michaux, J., Humbert, M., Soto-Cabrera, D., Benonisson, H., Silvério-Alves, R., Gomez-Jimenez, D., Bernardo, C., Bauden, M., Andersson, R., Höglund, M., Miharada, K. & 9 others, Nakamura, Y., Hugues, S., Greiff, L., Lindstedt, M., Rosa, F. F., Pires, C. F., Bassani-Sternberg, M., Svane, Inge Marie & Pereira, C. F., 2023, In: Science immunology. 8, 85, 20 p., eadd4817.

      Research output: Contribution to journal › Journal article › Research › peer-review

    7. Published

      TCR-engaging scaffolds selectively expand antigen-specific T-cells with a favorable phenotype for adoptive cell therapy

      Tvingsholm, S. A., Frej, M. S., Rafa, V. M., Hansen, U. K., Ormhøj, M., Tyron, A., Jensen, A. W. P., Kadivar, M., Bentzen, A. K., Munk, K. K., Aasbjerg, G. N., Ternander, J. S. H., Heeke, C., Tamhane, T., Schmess, C., Funt, S. A., Kjeldsen, J. W., Kverneland, A. H., Met, Ö., Draghi, A. & 4 others, Jakobsen, S. N., Donia, M., Svane, Inge Marie & Hadrup, S. R., 2023, In: Journal for ImmunoTherapy of Cancer. 11, 8, 16 p., e006847.

      Research output: Contribution to journal › Journal article › Research › peer-review

    8. 2022
    9. Published

      Anti-PD-L1/PD-L2 therapeutic vaccination in untreated chronic lymphocytic leukemia patients with unmutated IgHV

      Klausen, U., Grauslund, J. H., Jørgensen, N. G. D., Ahmad, S. M., Jonassen, M., Weis-Banke, S. E., Martinenaite, E., Pedersen, L. B., Lisle, T. L., Gang, Anne Ortved, Enggaard, L., Hansen, M., Holmström, M. O., Met, Özcan, Svane, Inge Marie, Niemann, Carsten, Pedersen, Lars Møller & Andersen, Mads Hald, 2022, In: Frontiers in Oncology. 12, 1023015.

      Research output: Contribution to journal › Journal article › Research › peer-review

    10. Published

      Arginase-2-specific cytotoxic T cells specifically recognize functional regulatory T cells

      Weis-Banke, S. E., Lisle, T. L., Perez Penco, Maria, Schina, A., Hübbe, M. L., Siersbæk, M., Holmström, M. O., Jørgensen, M. A., Svane, Inge Marie, Met, Özcan, Ødum, Niels, Madsen, Daniel Hargbøl, dqp123, dqp123, Grøntved, L. & Andersen, Mads Hald, 2022, In: Journal for ImmunoTherapy of Cancer. 10, 10, e005326.

      Research output: Contribution to journal › Journal article › Research › peer-review

    11. Published

      Calreticulin mutant myeloproliferative neoplasms induce MHC-I skewing, which can be overcome by an optimized peptide cancer vaccine

      Gigoux, M., Holmström, M. O., Zappasodi, R., Park, J. J., Pourpe, S., Bozkus, C. C., Mangarin, L. M. B., Redmond, D., Verma, S., Schad, S., George, M. M., Venkatesh, D., Ghosh, A., Hoyos, D., Molvi, Z., Kamaz, B., Marneth, A. E., Duke, W., Leventhal, M. J., Jan, M. & 23 others, Ho, V. T., Hobbs, G. S., Knudsen, T. A., Skov, V., Kjær, L., Larsen, T. S., Hansen, D. L., Lindsley, R. C., Hasselbalch, Hans Carl, Grauslund, J. H., Lisle, T. L., Met, Özcan, Wilkinson, P., Greenbaum, B., Sepulveda, M. A., Chan, T., Rampal, R., Andersen, Mads Hald, Abdel-Wahab, O., Bhardwaj, N., Wolchok, J. D., Mullally, A. & Merghoub, T., 2022, In: Science Translational Medicine. 14, 649, eaba4380.

      Research output: Contribution to journal › Journal article › Research › peer-review

    12. Published

      Clinical advances and ongoing trials on mRNA vaccines for cancer treatment

      Lorentzen, C. L., Haanen, J. B., Met, Özcan & Svane, Inge Marie, 2022, In: The Lancet Oncology. 23, 10, p. e450-e458

      Research output: Contribution to journal › Review › Research › peer-review

    13. Published

      Highly efficient PD-1-targeted CRISPR-Cas9 for tumor-infiltrating lymphocyte-based adoptive T cell therapy

      Chamberlain, C. A., Bennett, Eric Paul, Kverneland, Anders Handrup, Svane, Inge Marie, dqp123, dqp123 & Met, Özcan, 2022, In: Molecular Therapy - Oncolytics. 24, p. 417-428 12 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    14. Published

      Peptide vaccination activating Galectin-3-specific T cells offers a novel means to target Galectin-3-expressing cells in the tumor microenvironment

      Bendtsen, S. K., Perez Penco, Maria, Hübbe, M. L., Martinenaite, E., Orebo Holmström, M., Weis-Banke, S. E., Grønne Dahlager Jørgensen, N., Jørgensen, M. A., Munir Ahmad, S., Jensen, K. M., Friese, C., Lundsager, M. T., Johansen, A. Z., Carretta, M., Ødum, Niels, Met, Özcan, Svane, Inge Marie, Madsen, Daniel Hargbøl & Andersen, Mads Hald, 2022, In: OncoImmunology. 11, 1, 2026020.

      Research output: Contribution to journal › Journal article › Research › peer-review

    15. Published

      Tumor-Infiltrating Lymphocyte Therapy or Ipilimumab in Advanced Melanoma.

      Rohaan, M. W., Borch, T. H., Van Den Berg, J. H., Met, Ö., Kessels, R., Geukes Foppen, M. H., Stoltenborg Granhøj, J., Nuijen, B., Nijenhuis, C., Jedema, I., Van Zon, M., Scheij, S., Beijnen, J. H., Hansen, M., Voermans, C., Noringriis, I. M., Monberg, T. J., Holmstroem, R. B., Wever, L. D. V., Van Dijk, M. & 37 others, Grijpink-Ongering, L. G., Valkenet, L. H. M., Torres Acosta, A., Karger, M., Borgers, J. S. W., Ten Ham, R. M. T., Retèl, V. P., Van Harten, W. H., Lalezari, F., Van Tinteren, H., Van Der Veldt, A. A. M., Hospers, G. A. P., Stevense-Den Boer, M. A. M., Suijkerbuijk, K. P. M., Aarts, M. J. B., Piersma, D., Van Den Eertwegh, A. J. M., De Groot, J. W. B., Vreugdenhil, G., Kapiteijn, E., Boers-Sonderen, M. J., Fiets, W. E., Van Den Berkmortel, F. W. P. J., Ellebaek, E., Hølmich, Lisbet Rosenkrantz, Van Akkooi, A. C. J., Van Houdt, W. J., Wouters, M. W. J. M., Van Thienen, J. V., Blank, C. U., Meerveld-Eggink, A., Klobuch, S., Wilgenhof, S., Schumacher, T. N., dqp123, dqp123, Svane, Inge Marie & Haanen, J. B. A. G., 2022, In: New England Journal of Medicine. 387, 23, p. 2113-2125 13 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    16. Published

      Tumor-infiltrating lymphocytes for adoptive cell therapy: recent advances, challenges, and future directions

      Granhøj, J. S., Jensen, Agnete Witness Præst, Presti, M., Met, Özcan, Svane, Inge Marie & dqp123, dqp123, 2022, In: Expert Opinion on Biological Therapy. 22, 5, p. 627-641 15 p.

      Research output: Contribution to journal › Review › Research › peer-review

    17. 2021
    18. Published

      Therapeutic Cancer Vaccination With a Peptide Derived From the Calreticulin Exon 9 Mutations Induces Strong Cellular Immune Responses in Patients With CALR-Mutant Chronic Myeloproliferative Neoplasms

      Handlos Grauslund, J., Holmström, M. O., Jørgensen, N. G., Klausen, U., Weis-Banke, S. E., El Fassi, D., Schöllkopf, C., Clausen, M. B., Gjerdrum, L. M. R., Breinholt, M. F., Kjeldsen, J. W., Hansen, M., Koschmieder, S., Chatain, N., Novotny, G. W., Petersen, J., Kjær, L., Skov, V., Met, Ö., Svane, I. M. & 2 others, Hasselbalch, Hans Carl & Andersen, Mads Hald, 26 Feb 2021, In: Frontiers in Oncology. 11, 17 p., 637420.

      Research output: Contribution to journal › Journal article › Research › peer-review

    19. Published

      Cytotoxic T cells isolated from healthy donors and cancer patients kill TGFβ-expressing cancer cells in a TGFβ-dependent manner

      Holmström, M. O., Mortensen, R. E. J., Pavlidis, A. M., Martinenaite, E., Weis-Banke, S. E., Aaboe-Jørgensen, M., Bendtsen, S. K., Met, Özcan, Pedersen, A. W., Donia, M., Svane, Inge Marie & Andersen, Mads Hald, Feb 2021, In: Cellular and Molecular Immunology. 18, 2, p. 415-426 12 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    20. Published

      ACT Up TIL Now: The Evolution of Tumor-Infiltrating Lymphocytes in Adoptive Cell Therapy for the Treatment of Solid Tumors

      Morgan Hulen , T., Chamberlain, C. A., Svane, Inge Marie & Met, Özcan, 2021, In: Immuno. 1, 3, p. 194-211

      Research output: Contribution to journal › Journal article › Research › peer-review

    21. Published

      An immunogenic first-in-human immune modulatory vaccine with PD-L1 and PD-L2 peptides is feasible and shows early signs of efficacy in follicular lymphoma

      Klausen, U., Grønne Dahlager Jørgensen, N., Grauslund, J. H., Munir Ahmad, S., Gang, Anne Ortved, Martinenaite, E., Weis-Banke, S. E., Breinholt, M. F., Novotny, G. W., Kjeldsen, J. W., Orebo Holmström, M., Pedersen, L. B., Poulsen, C. B., Hansen, P. B., Met, Özcan, Svane, Inge Marie, Niemann, Carsten, Pedersen, Lars Møller & Andersen, Mads Hald, 2021, In: OncoImmunology. 10, 1, 1975889.

      Research output: Contribution to journal › Journal article › Research › peer-review

    22. Published

      Clinical efficacy of T-cell therapy after short-term BRAF-inhibitor priming in patients with checkpoint inhibitor-resistant metastatic melanoma

      Borch, T. H., Harbst, K., Rana, A. H., Andersen, R., Martinenaite, E., Kongsted, P., Pedersen, M., Nielsen, M., Kjeldsen, J. W., Kverneland, Anders Handrup, Lauss, M., Hølmich, Lisbet Rosenkrantz, Hendel, Helle Westergren, Met, Özcan, Jönsson, G., dqp123, dqp123 & Svane, Inge Marie, 2021, In: Journal for ImmunoTherapy of Cancer. 9, 7, 15 p., e00270.

      Research output: Contribution to journal › Journal article › Research › peer-review

    23. Published

      Mitochondrial-Linked De Novo Pyrimidine Biosynthesis Dictates Human T-Cell Proliferation but Not Expression of Effector Molecules

      Peeters, M. J. W., Aehnlich, P., Pizzella, A., Mølgaard, K., Seremet, T., Met, Özcan, Rasmussen, Lene Juel, thor Straten, P. & Desler, Claus, 2021, In: Frontiers in Immunology. 12, 718863.

      Research output: Contribution to journal › Journal article › Research › peer-review

    24. Published

      Real-time monitoring of mitochondrial respiration in cytokine-differentiated human primary T cells

      Mølgaard, K., Rahbech, Anne, Met, Özcan, Svane, Inge Marie, Straten, P., Desler, Claus & Peeters, M. J. W., 2021, In: Journal of Visualized Experiments. 176, e62984.

      Research output: Contribution to journal › Journal article › Research › peer-review

    25. Published

      The Thioredoxin-Interacting Protein TXNIP Is a Putative Tumour Suppressor in Cutaneous T-Cell Lymphoma

      Stolearenco, V., Levring, T. B., Nielsen, H. M., Lindahl, L., Fredholm, S., Kongsbak-Wismann, Martin, Willerslev-Olsen, A., Buus, Terkild Brink, Nastasi, C., Hu, T., Gluud, Maria, Côme, Christophe Roger Michel, Krejsgaard, T., Iversen, L., Bonefeld, Charlotte Menne, Grønbæk, Kirsten, Met, Özcan, Woetmann, Anders , Ødum, Niels & Geisler, Carsten, 2021, In: Dermatology. 237, 2, p. 283-290 8 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    26. Published

      Vaccination against pd-l1 with io103 a novel immune modulatory vaccine in basal cell carcinoma: A phase iia study

      Jørgensen, N. G., Kaae, Jeanette, Grauslund, J. H., Met, Özcan, Nielsen, S. L., Pedersen, A. W., Svane, Inge Marie, Ehrnrooth, E., Andersen, Mads Hald, Zachariae, Claus & Skov, Lone, 2021, In: Cancers. 13, 4, p. 1-15 15 p., 911.

      Research output: Contribution to journal › Journal article › Research › peer-review

    27. Published

      Vγ9Vδ2 T Cells Concurrently Kill Cancer Cells and Cross-Present Tumor Antigens

      Holmen Olofsson, G., Idorn, M., Carnaz Simões, A. M., Aehnlich, P., Skadborg, S. K., Noessner, E., Debets, R., Moser, B., Met, Özcan & thor Straten, P., 2021, In: Frontiers in Immunology. 12, 645131.

      Research output: Contribution to journal › Journal article › Research › peer-review

    28. 2020
    29. Published

      Adoptive cell therapy in combination with checkpoint inhibitors in ovarian cancer

      Kverneland, Anders Handrup, Pedersen, M., Wulff Westergaard, M. C., Nielsen, M., Borch, T. H., Olsen, L. R., Aasbjerg, G., Santegoets, S. J., van der Burg, S. H., Milne, K., Nelson, B. H., Met, Özcan, dqp123, dqp123 & Svane, Inge Marie, 2020, In: OncoTarget. 11, 22, p. 2092-2105 14 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    30. Published

      CTLA-4 blockade boosts the expansion of tumor-reactive CD8+ tumor-infiltrating lymphocytes in ovarian cancer

      Friese, C., Harbst, K., Borch, T. H., Westergaard, M. C. W., Pedersen, M., Kverneland, A., Jönsson, G., dqp123, dqp123, Svane, Inge Marie & Met, Özcan, 2020, In: Scientific Reports. 10, 1, 12 p., 3914.

      Research output: Contribution to journal › Journal article › Research › peer-review

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    ID: 33971757