Skin Immunology Research Center

  1. 2023
  2. Published

    Human skin-resident CD8+ T cells require RUNX2 and RUNX3 for induction of cytotoxicity and expression of the integrin CD49a

    Zitti, B., Hoffer, E., Zheng, Wenning, Pandey, R. V., Schlums, H., Perinetti Casoni, G., Fusi, I., Nguyen, L., Kärner, J., Kokkinou, E., Carrasco, A., Gahm, J., Ehrström, M., Happaniemi, S., Keita, Å. V., Hedin, C. R. H., Mjösberg, J., Eidsmo, Liv & Bryceson, Y. T., 2023, In: Immunity. 56, 6, p. 1285-1302.e7

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    Imbalanced IL-1B and IL-18 Expression in Sézary Syndrome

    Manfrere, K. C. G., Torrealba, M. P., Ferreira, F. M., de Sousa, E. S. A., Miyashiro, D., Teixeira, F. M. E., Custódio, R. W. A., Nakaya, H. I., Ramos, Y. A. L., Sotto, M. N., Woetmann, Anders , Ødum, Niels, Duarte, A. J. D. S., Sanches, J. A. & Sato, M. N., 2023, In: International Journal of Molecular Sciences. 24, 5, 4674.

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    Immunology in the Copenhagen area: a renewed focus on diseases of the skin

    Coquet, Jonathan, 2023, In: Immunology and Cell Biology. 101, 7, p. 598-599

    Research output: Contribution to journalEditorialResearch

  5. Published

    Impact of U2AF1 mutations on circular RNA expression in myelodysplastic neoplasms

    Wedge, E., Ahmadov, U., Hansen, T. B., Gao, Z., Tulstrup, Morten Rytter, Côme, Christophe Roger Michel, Nonavinkere Srivatsan, S., Ahmed, T., Jespersen, Jakob Schmidt, Schlotmann, Balthasar Clemens, Schöllkopf, C., Raaschou-Jensen, K., Ødum, Niels, Kjems, J., Bak, R. O., Walter, M. J., Grønbæk, Kirsten & Kristensen, L. S., 2023, In: Leukemia. 37, p. 1113-1125

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. E-pub ahead of print

    Investigation of plaque psoriasis relapse after secukinumab withdrawal in patients from two Phase 3 studies

    Lebwohl, M., Iversen, L., Eidsmo, Liv, Krueger, J. G., Suárez-Fariñas, M., Tomalin, L., Kolbinger, F., You, R. & Milutinovic, M., 2023, (E-pub ahead of print) In: Clinical and Experimental Dermatology.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    Keratitis-ichthyosis-deafness syndrome and hidradenitis suppurativa

    Travis, L., Ou Yang, J., Andersen, Rune Kjærsgaard, Skovby, F., Jemec, Gregor & Saunte, Ditte Marie, 2023, In: JAAD Case Reports. 38, p. 158-162 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    Laboratory mice with a wild microbiota generate strong allergic immune responses

    Ma, J., Urgard, E., Runge, S., Classon, C. H., Mathä, L., Stark, J. M., Cheng, L., Álvarez, J. A., von Zedtwitz, S., Baleviciute, A., Hoyer, S. M., Li, M., Gernand, A. M., Osbelt, L., Bielecka, A. A., Lesker, T. R., Huang, H. J., Vrtala, S., Boon, L., Beyaert, R. & 7 others, Adner, M., Martinez Gonzalez, I., Strowig, T., Du, J., Nylén, S., Rosshart, S. P. & Coquet, Jonathan, 2023, In: Science immunology. 8, 87, p. 1-16 adf7702.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published
  10. Published

    Malignant T cells induce skin barrier defects through cytokine-mediated JAK/STAT signaling in cutaneous T-cell lymphoma

    Gluud, M., Pallesen, E. M. H., Buus, T. B., Gjerdrum, L. M. R., Lindahl, L. M., Kamstrup, M. R., Bzorek, M., Danielsen, M., Bech, R., Monteiro, M. N., Blümel, E., Willerslev-Olsen, A., Lykkebo-Valløe, A., Vadivel, C. K., Krejsgaard, T., Bonefeld, C. M., Geisler, C., Becker, J. C., Koralov, S. B., Iversen, L. & 3 others, Litman, Thomas, Woetmann, Anders & Ødum, Niels, 2023, In: Blood. 141, 2, p. 180-193 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    Measurement of Ara h 6 can improve diagnosis in patients suspected of peanut allergy

    Eller, E., Baumann, Katrine, Skov, P. S. & Bindslev-Jensen, C., 2023, In: Clinical and Experimental Allergy. 53, 6, p. 683-685

    Research output: Contribution to journalLetterResearchpeer-review

  12. Published

    Old Sins Cast Long Shadows: News on Staphylococcus aureus in Cutaneous T Cell Lymphoma

    Guenova, E. & Ødum, Niels, 2023, In: Journal of Investigative Dermatology. 144, 1, p. 8-10 3 p.

    Research output: Contribution to journalLetterResearchpeer-review

  13. Published

    Pharmacokinetics of Locally Applied Antibiotic Prophylaxis for Implant-Based Breast Reconstruction

    Hemmingsen, Mathilde Nejrup, Bennedsen, A. K., Kullab, R. B., Norlin, C. B., Ørholt, M., Larsen, A., Bue, M., Lichtenberg, Mads, Hertz, Frederik Boëtius, Damsgaard, T. E., Vester-Glowinski, Peter Viktor, Sørensen, Søren Johannes, Bjarnsholt, Thomas & Herly, Mikkel, 2023, In: JAMA network open. 6, 12, 11 p., E2348414.

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    Phenotypic plasticity of malignant T cells in blood and skin of a Sézary syndrome patient revealed by single cell transcriptomics

    Peiffer, L., Gambichler, T., Buus, Terkild Brink, Horny, K., Gravemeyer, J., Furtmann, F., Spassova, I., Kubat, L., Susok, L., Stranzenbach, R., Srinivas, N., Ødum, Niels & Becker, J. C., 2023, In: Frontiers in Oncology. 13, 1090592.

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Published

    Plasma YKL-40 is associated with prognosis in patients with metastatic pancreatic cancer receiving immune checkpoint inhibitors in combination with radiotherapy

    Johansen, A. Z., Novitski, Sif Ingibergsdóttir, Hjaltelin, Jessica Xin, Theile, S., Boisen, M. K., Brunak, Søren, Madsen, Daniel Hargbøl, Nielsen, Dorte Lisbet & Chen, I. M., 2023, In: Frontiers in Immunology. 14, 10 p., 1228907.

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. Published

    Positive basophil histamine release assay predicts insufficient response to standard-dosed omalizumab in patients with chronic spontaneous urticaria

    Baumann, Katrine, Jørgensen, A. H. R., Sørensen, J. A., Zhang, D. G., Ghazanfar, M. N., Skov, P. S., Woetmann, Anders , Vestergaard, C., Maurer, M. & Thomsen, Simon Francis, 2023, In: Clinical and Experimental Allergy. 53, 12, p. 1318-1321

    Research output: Contribution to journalLetterResearchpeer-review

  17. Published

    Pre-existing TGF-β-specific T-cell immunity in patients with pancreatic cancer predicts survival after checkpoint inhibitors combined with radiotherapy

    Mortensen, R. E. J., Holmström, M. O., Lisle, T. L., Hasselby, Jane Preuss, Willemoe, G. L., Met, Özcan, Svane, Inge Marie, Johansen, Julia Sidenius, Nielsen, Dorte Lisbet, Chen, I. M. & Andersen, Mads Hald, 2023, In: Journal for ImmunoTherapy of Cancer. 11, 3

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    Prevalence and predictors of hypothyroidism in patients with chronic spontaneous urticaria

    Pedersen, N. H., Zhang, D. G., Sorensen, J. A., Vestergaard, C., Baumann, Katrine, Ghazanfar, M. N. & Thomsen, Simon Francis, 2023, In: Experimental Dermatology. 32, 9, 3.

    Research output: Contribution to journalComment/debateResearchpeer-review

  19. Published

    Primary skin abscess microbiota a systematic review

    Kursawe Larsen, C., Andersen, Rune Kjærsgaard, Saunte, Ditte Marie & Jemec, Gregor, 2023, In: APMIS : acta pathologica, microbiologica, et immunologica Scandinavica. 131, 5, p. 183-188

    Research output: Contribution to journalReviewResearchpeer-review

  20. Published

    Prognostic Significance and Management of Sentinel Nodes in the Triangular Intermuscular Space of Patients with Melanoma

    Schønfeldt, Trine, Thompson, J. F., Lo, S., Drzewiecki, K. T., Stretch, J., Saw, R. P. M., Spillane, A., Shannon, K., Uren, R. F., Chakera, A. H. & Nieweg, O. E., 2023, In: Annals of Surgical Oncology. 30, p. 2354–2361

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. Published

    Secukinumab demonstrates superiority over narrow-band ultraviolet B phototherapy in new-onset moderate to severe plaque psoriasis patients: Week 52 results from the STEPIn study

    Iversen, L., Conrad, C., Eidsmo, Liv, Costanzo, A., Narbutt, J., Pinter, A., Kingo, K., Rivera diaz, R., Kolbinger, F., Nanna, M., Frueh, J. A. & Jagiello, P., 2023, In: Journal of the European Academy of Dermatology and Venereology. 37, 5, p. 1004-1016

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Published

    Skin infiltrating NK cells in cutaneous T-cell lymphoma are increased in number and display phenotypic alterations partially driven by the tumor

    Scheffschick, A., Nenonen, J., Xiang, M., Winther, A. H., Ehrström, M., Wahren-Herlenius, M., Eidsmo, Liv & Brauner, H., 2023, In: Frontiers in Immunology. 14, 1168684.

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Published

    The Proteome of Hand Eczema Assessed by Tape Stripping

    Sølberg, J. B. K., Quaade, A. S., Drici, L., Sulek, K., Ulrich, N. H., Løvendorf, Marianne Bengtson, Thyssen, Jacob Pontoppidan, Mann, Matthias, Dyring-Andersen, Beatrice & Johansen, Jeanne Duus, 2023, In: Journal of Investigative Dermatology. 143, p. 1559-1568

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Published

    The cIAP ubiquitin ligases sustain type 3 γδ T cells and ILC during aging to promote barrier immunity

    Rizk, John, Mörbe, U. M., Agerholm, R., Baglioni, M. V., Catafal Tardos, E., Fares Da Silva, M. G. F., Ulmert, I., Kadekar, D., Viñals, M. T. & Bekiaris, V., 2023, In: Journal of Experimental Medicine. 220, 8, 26 p., e20221534.

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published
  26. Published

    Therapeutic cancer vaccination against mutant calreticulin in myeloproliferative neoplasms induces expansion of specific T cells in the periphery but specific T cells fail to enrich in the bone marrow

    Holmström, M. O., Andersen, M., Traynor, S., Ahmad, S. M., Lisle, T. L., Handlos Grauslund, J., Skov, V., Kjær, L., Ottesen, J. T., Gjerstorff, M. F., Hasselbalch, Hans Carl & Andersen, Mads Hald, 2023, In: Frontiers in Immunology. 14, 14 p., 1240678.

    Research output: Contribution to journalJournal articleResearchpeer-review

  27. Published

    Validation of a Novel EUS-FNB-Derived Organoid Co-Culture System for Drug Screening in Patients with Pancreatic Cancer

    Grützmeier, S. E., Kovacevic, B., Vilmann, Peter, Rift, Charlotte Vestrup, Melchior, L. C., Holmström, M. O., Brink, L., Hassan, H., Karstensen, John Gásdal, Grossjohann, Hanne Sønder, Chiranth, D., Toxværd, A., Hansen, C. P., Høgdall, Estrid Vilma Solyom, Hasselby, Jane Preuss & Klausen, P., 2023, In: Cancers. 15, 14, 18 p., 3677.

    Research output: Contribution to journalJournal articleResearchpeer-review

  28. Published

    Vitamin D and SARS-CoV-2

    Feentved Ødum, S. L. & Kongsbak-Wismann, Martin, 2023, In: Basic and Clinical Pharmacology and Toxicology. 133, 1, p. 6-15

    Research output: Contribution to journalReviewResearchpeer-review

  29. Published

    mRNA COVID-19 vaccine elicits potent adaptive immune response without the acute inflammation of SARS-CoV-2 infection

    Ivanova, E. N., Shwetar, J., Devlin, J. C., Buus, T. B., Gray-Gaillard, S., Koide, A., Cornelius, A., Samanovic, M. I., Herrera, A., Mimitou, E. P., Zhang, C., Karmacharya, T., Desvignes, L., Ødum, N., Smibert, P., Ulrich, R. J., Mulligan, M. J., Koide, S., Ruggles, K. V., Herati, R. S. & 1 others, Koralov, S. B., 2023, In: iScience. 26, 12, p. 1-19 108572.

    Research output: Contribution to journalJournal articleResearchpeer-review

  30. 2022
  31. Published

    High threshold efficacy responses in moderate-to-severe atopic dermatitis are associated with additional quality of life benefits: pooled analyses of abrocitinib monotherapy studies in adults and adolescents

    Stander, S., Bhatia, N., Gooderham, M. J., Silverberg, J., Thyssen, Jacob Pontoppidan, Biswas, P., DiBonaventura, M., Romero, W. & Farooqui, S. A., 6 May 2022, In: Journal of the European Academy of Dermatology and Venereology. 36, 8, p. 1308-1317 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  32. Published

    Conjunctivitis in adult patients with moderate-to-severe atopic dermatitis: results from five tralokinumab clinical trials

    Wollenberg, A., Beck, L. A., de Bruin Weller, M., Simpson, E. L., Imafuku, S., Boguniewicz, M., Zachariae, R., Olsen, C. K. & Thyssen, Jacob Pontoppidan, Mar 2022, In: British Journal of Dermatology. 186, 3, p. 453-465 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  33. Published

    Disease burden, symptoms, and use of analgesics in patients with psoriasis with or without psoriatic arthritis: A cross-sectional study

    Loft, N., Nguyen, T. T., Kristensen, Lars Erik Vølund, Thyssen, Jacob Pontoppidan & Egeberg, Alexander, Mar 2022, In: Journal of the American Academy of Dermatology. 86, 3, p. 590-597 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  34. Published

    Improvement in symptoms of anxiety and depression in patients with atopic dermatitis after treatment with baricitinib

    Thyssen, Jacob Pontoppidan, Lio, P., Ball, S., Pierce, E., Sun, L., Chen, Y., Tan, J. K. L. & Augustin, M., Feb 2022, In: Journal of the European Academy of Dermatology and Venereology. 36, 2, p. E147-E150 4 p.

    Research output: Contribution to journalComment/debateResearchpeer-review

  35. Published

    Does aluminium in sunscreens cause dermatitis in children with aluminium contact allergy: A repeated open application test study

    Hoffmann, S. S., Elberling, Jesper Vraamark, Thyssen, Jacob Pontoppidan, Hansen, K. S. & Johansen, Jeanne Duus, Jan 2022, In: Contact Dermatitis. 86, 1, p. 9-14 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  36. Published

    Family burden of hospital-managed pediatric atopic dermatitis: A nationwide registry-based study

    Vittrup, I., Droitcourt, C., Andersen, Y. M. F., Skov, Lone, Egeberg, Alexander, Delevry, D., Fenton, M. C. & Thyssen, Jacob Pontoppidan, Jan 2022, In: Pediatric Allergy and Immunology. 33, 1, e13693.

    Research output: Contribution to journalJournal articleResearchpeer-review

  37. Published

    The risk of COVID-19 infection in patients with atopic dermatitis: A retrospective cohort study

    Wu, J. J., Martin, A., Liu, J., Thatiparthi, A., Ge, S., Egeberg, Alexander & Thyssen, Jacob Pontoppidan, Jan 2022, In: Journal of the American Academy of Dermatology. 86, 1, p. 243-245 3 p.

    Research output: Contribution to journalComment/debateResearchpeer-review

  38. Published

    Staphylococcus aureus and Antibiotics in Cutaneous T-Cell Lymphoma

    Lindahl, L. M., Iversen, L., Ødum, Niels & Kilian, Mogens, 2022, In: Dermatology. 238, p. 551–553

    Research output: Contribution to journalComment/debateResearchpeer-review

  39. Published

    A comparison between self-reported hand eczema and self-reported signs and symptoms of skin lesions indicating hand eczema

    Yüksel, Y. T., Thyssen, Jacob Pontoppidan, Nørreslet, L. B., Flachs, E. M., Ebbehøj, N. E. & Agner, Tove, 2022, In: Contact Dermatitis. 87, 6, p. 528-534

    Research output: Contribution to journalJournal articleResearchpeer-review

  40. Published
  41. Published

    Anti-PD-L1/PD-L2 therapeutic vaccination in untreated chronic lymphocytic leukemia patients with unmutated IgHV

    Klausen, U., Grauslund, J. H., Jørgensen, N. G. D., Ahmad, S. M., Jonassen, M., Weis-Banke, S. E., Martinenaite, E., Pedersen, L. B., Lisle, T. L., Gang, Anne Ortved, Enggaard, L., Hansen, M., Holmström, M. O., Met, Özcan, Svane, Inge Marie, Niemann, Carsten, Pedersen, Lars Møller & Andersen, Mads Hald, 2022, In: Frontiers in Oncology. 12, 1023015.

    Research output: Contribution to journalJournal articleResearchpeer-review

  42. Published

    Arginase-2-specific cytotoxic T cells specifically recognize functional regulatory T cells

    Weis-Banke, S. E., Lisle, T. L., Perez Penco, Maria, Schina, A., Hübbe, M. L., Siersbæk, M., Holmström, M. O., Jørgensen, M. A., Svane, Inge Marie, Met, Özcan, Ødum, Niels, Madsen, Daniel Hargbøl, dqp123, dqp123, Grøntved, L. & Andersen, Mads Hald, 2022, In: Journal for ImmunoTherapy of Cancer. 10, 10, e005326.

    Research output: Contribution to journalJournal articleResearchpeer-review

  43. Published

    Artificial Nails and Long-lasting Nail Polish in Danish Hairdressers: Self-use, Occupational Exposure and Related Eczema

    Havmose, M., Thyssen, Jacob Pontoppidan, Zachariae, Claus & Johansen, Jeanne Duus, 2022, In: Acta Dermato-Venereologica. 102, adv00818.

    Research output: Contribution to journalJournal articleResearchpeer-review

  44. Published

    Baricitinib improves symptoms in patients with moderate-to-severe atopic dermatitis and inadequate response to topical corticosteroids: patient-reported outcomes from two randomized monotherapy phase III trials

    Reich, K., DeLozier, A. M., Nunes, F. P., Thyssen, Jacob Pontoppidan, Eichenfield, L. F., Wollenberg, A., Ross Terres, J. A., Watts, S. D., Chen, Y. F., Simpson, E. L. & Silverberg, J. I., 2022, In: Journal of Dermatological Treatment. 33, 3, p. 1521-1530 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  45. Published

    Blockade of beta-adrenergic receptors reduces cancer growth and enhances the response to anti-CTLA4 therapy by modulating the tumor microenvironment

    Fjæstad, K. Y., Rømer, A. M. A., Goitea, V., Johansen, A. Z., Thorseth, M. L., Carretta, M., Engelholm, Lars Henning, Grøntved, L., Junker, N. & Madsen, Daniel Hargbøl, 2022, In: Oncogene. 41, p. 1364-1375

    Research output: Contribution to journalJournal articleResearchpeer-review

  46. Published
  47. Published

    Calreticulin mutant myeloproliferative neoplasms induce MHC-I skewing, which can be overcome by an optimized peptide cancer vaccine

    Gigoux, M., Holmström, M. O., Zappasodi, R., Park, J. J., Pourpe, S., Bozkus, C. C., Mangarin, L. M. B., Redmond, D., Verma, S., Schad, S., George, M. M., Venkatesh, D., Ghosh, A., Hoyos, D., Molvi, Z., Kamaz, B., Marneth, A. E., Duke, W., Leventhal, M. J., Jan, M. & 23 others, Ho, V. T., Hobbs, G. S., Knudsen, T. A., Skov, V., Kjær, L., Larsen, T. S., Hansen, D. L., Lindsley, R. C., Hasselbalch, Hans Carl, Grauslund, J. H., Lisle, T. L., Met, Özcan, Wilkinson, P., Greenbaum, B., Sepulveda, M. A., Chan, T., Rampal, R., Andersen, Mads Hald, Abdel-Wahab, O., Bhardwaj, N., Wolchok, J. D., Mullally, A. & Merghoub, T., 2022, In: Science Translational Medicine. 14, 649, eaba4380.

    Research output: Contribution to journalJournal articleResearchpeer-review

  48. Published

    Can we increase the drug survival time of biologic therapies in hidradenitis suppurativa?

    Ring, H. C., Frew, J. W., Thyssen, Jacob Pontoppidan, Egeberg, Alexander & Thomsen, Simon Francis, 2022, In: Clinical and Experimental Dermatology. 47, 8, p. 1585-1586 2 p.

    Research output: Contribution to journalComment/debateResearchpeer-review

  49. Published

    Care pathways in atopic dermatitis: a retrospective population-based cohort study

    von Kobyletzki, L., Ballardini, N., Henrohn, D., Neary, M. P., Ortsater, G., Geale, K., Rieem Dun, A., Lindberg, I., De Geer, A., Neregard, P., Cha, A., Cappelleri, J. C., Romero, W. & Thyssen, Jacob Pontoppidan, 2022, In: Journal of the European Academy of Dermatology and Venereology. 36, 9, p. 1456-1466

    Research output: Contribution to journalJournal articleResearchpeer-review

  50. Published

    Chitooligosaccharides Improve the Efficacy of Checkpoint Inhibitors in a Mouse Model of Lung Cancer

    Johansen, A. Z., Carretta, M., Thorseth, M. L., Khan, S., Fjæstad, K. Y., Brøchner, Christian Beltoft, Linder, H., Ankjærgaard, C., dqp123, dqp123, Chen, I., Nielsen, Dorte Lisbet, Behrens, C. P. & Madsen, Daniel Hargbøl, 2022, In: Pharmaceutics. 14, 5, 1046.

    Research output: Contribution to journalJournal articleResearchpeer-review

  51. Published

    Concomitant Inhibition of FASN and SREBP Provides a Promising Therapy for CTCL

    Chi, C., Harth, Lisa, Ramírez Galera, Marina, Torrealba, M. P., Vadivel, Chella Krishna, Geisler, Carsten, Bonefeld, Charlotte Menne, Nielsen, Pia Rude, Bzorek, M., Becker, J. C., Gjerdrum, Lise Mette Rahbek, Ødum, Niels & Woetmann, Anders , 2022, In: Cancers. 14, 18, 4491.

    Research output: Contribution to journalJournal articleResearchpeer-review

  52. Published

    Copper release from metals may mask positive nickel spot test results

    Wennervaldt, M., Ahlström, M. G., Menné, T., Thyssen, Jacob Pontoppidan & Johansen, Jeanne Duus, 2022, In: Contact Dermatitis. 86, 5, p. 431-433 3 p.

    Research output: Contribution to journalJournal articleResearchpeer-review