Mads Gyrd-Hansen

Mads Gyrd-Hansen

Professor

ORCID: 0000-0001-5641-5019

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  1. A new functional assay for the diagnosis of X-linked inhibitor of apoptosis (XIAP) deficiency

    Ammann, S., Elling, R., Gyrd-Hansen, Mads, Dückers, G., Bredius, R., Burns, S. O., Edgar, J. D. M., Worth, A., Brandau, H., Warnatz, K., zur Stadt, U., Hasselblatt, P., Schwarz, K., Ehl, S. & Speckmann, C., 2014, In: Clinical and Experimental Immunology. 176, 3, p. 394-400 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  2. Published

    Heregulin-induced epigenetic regulation of the utrophin-A promoter.

    Basu, U., Gyrd-Hansen, Mads, Baby, S. M., Lozynska, O., Krag, T. O. B., Jensen, C. J., Frödin, Morten & Khurana, T. S., 2007, In: FEBS Letters. 581, 22, p. 4153-8 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  3. HSV1 VP1-2 deubiquitinates STING to block type I interferon expression and promote brain infection

    Bodda, C., Reinert, L. S., Fruhwürth, S., Richardo, T., Sun, C., Zhang, B., Kalamvoki, M., Pohlmann, A., Mogensen, T. H., Bergström, P., Agholme, L., O'Hare, P., Sodeik, B., Gyrd-Hansen, Mads, Zetterberg, H. & Paludan, S. R., 2020, In: The Journal of Experimental Medicine. 217, 7

    Research output: Contribution to journal › Journal article › Research › peer-review

  4. Inflammatory Signaling by NOD-RIPK2 Is Inhibited by Clinically Relevant Type II Kinase Inhibitors

    Canning, P., Ruan, Q., Schwerd, T., Hrdinka, M., Maki, J. L., Saleh, D., Suebsuwong, C., Ray, S., Brennan, P. E., Cuny, G. D., Uhlig, H. H., Gyrd-Hansen, Mads, Degterev, A. & Bullock, A. N., 17 Sep 2015, In: Cell Chemical Biology. 22, 9, p. 1174-84 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  5. Published

    Inhibitor of apoptosis (IAP) proteins in regulation of inflammation and innate immunity

    Damgaard, R. B. & Gyrd-Hansen, Mads, 2011, In: Discovery Medicine. 11, 58, p. 221-31 11 p.

    Research output: Contribution to journal › Review › Research › peer-review

  6. Published

    The Ubiquitin Ligase XIAP Recruits LUBAC for NOD2 Signaling in Inflammation and Innate Immunity

    Damgaard, R. B., Nachbur, U., Yabal, M., Wong, W. W., Fiil, Berthe Katrine, Kastirr, M., Rieser, E., Rickard, J. A., Bankovacki, A., Peschel, C., Ruland, J., Bekker-Jensen, Simon Holst, Mailand, Niels, Kaufmann, T., Strasser, A., Walczak, H., Silke, J., Jost, P. J. & Gyrd-Hansen, Mads, 2012, In: Molecular Cell. 46, 6, p. 746-58 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  7. Published

    Disease-causing mutations in the XIAP BIR2 domain impair NOD2-dependent immune signalling

    Damgaard, R. B., Fiil, Berthe Katrine, Speckmann, C., Yabal, M., Stadt, U. Z., Bekker-Jensen, Simon Holst, Jost, P. J., Ehl, S., Mailand, Niels & Gyrd-Hansen, Mads, 1 Jul 2013, In: E M B O Journal. 5, p. 1278-1295 18 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  8. JNK2 mediates TNF-induced cell death in mouse embryonic fibroblasts via regulation of both caspase and cathepsin protease pathways.

    Dietrich, N., Thastrup, J., Holmberg, C., Gyrd-Hansen, Mads, Fehrenbacher, N., Lademann, U., Lerdrup, M., Herdegen, T., Jäättelä, M. & Kallunki, T., 2004, In: Cell Death and Differentiation. 11, 3, p. 301-13 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  9. Published

    Symptomatic Males and Female Carriers in a Large Caucasian Kindred with XIAP Deficiency

    Dziadzio, M., Ammann, S., Canning, C., Boyle, F., Hassan, A., Cale, C., Elawad, M., Fiil, Berthe Katrine, Gyrd-Hansen, Mads, Salzer, U., Speckmann, C. & Grimbacher, B., 25 Jul 2015, In: Journal of Clinical Immunology. 35, 5, p. 439-444 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  10. SPATA2 Links CYLD to LUBAC, Activates CYLD, and Controls LUBAC Signaling

    Elliott, P. R., Leske, D., Hrdinka, M., Bagola, K., Fiil, Berthe Katrine, McLaughlin, S. H., Wagstaff, J., Volkmar, N., Christianson, J. C., Kessler, B. M., Freund, S. M. V., Komander, D. & Gyrd-Hansen, Mads, 15 Sep 2016, In: Molecular Cell. 63, 6, p. 990-1005 16 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  11. Published

    Molecular basis and regulation of OTULIN-LUBAC interaction

    Elliott, P. R., Al-Saoudi, S. V., Marco-Casanova, P., Fiil, Berthe Katrine, Keusekotten, K., Mailand, Niels, Freund, S. M. V., Gyrd-Hansen, Mads & Komander, D., 2014, In: Molecular Cell. 54, 3, p. 335-348 14 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  12. Published

    Regulation of CYLD activity and specificity by phosphorylation and ubiquitin-binding CAP-Gly domains

    Elliott, P. R., Leske, D., Wagstaff, J., Schlicher, L., Berridge, G., Maslen, S., Timmermann, F., Ma, B., Fischer, R., Freund, S. M. V., Komander, D. & Gyrd-Hansen, Mads, 2021, In: Cell Reports. 37, 1, 25 p., 109777.

    Research output: Contribution to journal › Journal article › Research › peer-review

  13. Sensitization to the lysosomal cell death pathway upon immortalization and transformation.

    Fehrenbacher, N., Gyrd-Hansen, Mads, Poulsen, B., Felbor, U., Kallunki, T., Boes, M., Weber, E., Leist, M. & Jäättelä, M., 2004, In: Cancer Research. 64, 15, p. 5301-10 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  14. Interaction mapping of endoplasmic reticulum ubiquitin ligases identifies modulators of innate immune signalling

    Fenech, E. J., Lari, F., Charles, P. D., Fischer, R., Laétitia-Thézénas, M., Bagola, K., Paton, A. W., Paton, J. C., Gyrd-Hansen, Mads, Kessler, B. M. & Christianson, J. C., 2 Jul 2020, In: eLife. 9

    Research output: Contribution to journal › Journal article › Research › peer-review

  15. Published

    Met1-linked Ubiquitination in Immune Signalling

    Fiil, Berthe Katrine & Gyrd-Hansen, Mads, Oct 2014, In: F E B S Journal. 81, 19, p. 4337-50 14 p.

    Research output: Contribution to journal › Review › Research › peer-review

  16. Published

    OTULIN deficiency causes auto-inflammatory syndrome

    Fiil, Berthe Katrine & Gyrd-Hansen, Mads, Nov 2016, In: Cell Research. 26, 11, p. 1176-1177 2 p.

    Research output: Contribution to journal › Journal article › Commissioned

  17. Published

    OTULIN Restricts Met1-Linked Ubiquitination to Control Innate Immune Signaling

    Fiil, Berthe Katrine, Damgaard, R. B., Wagner, S. A., Keusekotten, K., Fritsch, M., Bekker-Jensen, Simon Holst, Mailand, Niels, Choudhary, Chunaram, Komander, D. & Gyrd-Hansen, Mads, 27 Jun 2013, In: Molecular Cell. 50, 6, p. 818-30 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  18. Published

    The Met1-linked ubiquitin machinery in inflammation and infection

    Fiil, Berthe Katrine & Gyrd-Hansen, Mads, 2021, In: Cell Death and Differentiation. 28, p. 557–569

    Research output: Contribution to journal › Review › Research › peer-review

  19. Published

    IAPs: From caspase inhibitors to modulators of NF-κB, inflammation and cancer

    Gyrd-Hansen, Mads & Meier, P., 2010, In: Nature Reviews Cancer.

    Research output: Contribution to journal › Journal article › Commissioned › peer-review

  20. Published

    Apoptosome-independent activation of the lysosomal cell death pathway by caspase-9

    Gyrd-Hansen, Mads, Farkas, T., Fehrenbacher, N., Bastholm, L., Høyer-Hansen, M., Elling, F., Wallach, D., Flavell, R., Kroemer, G., Nylandsted, J. & Jaattela, Marja, 2006, In: Molecular and Cellular Biology. 26, 21, p. 7880-7891

    Research output: Contribution to journal › Journal article › Research › peer-review

  21. Sp1 and the ets-related transcription factor complex GABP alpha/beta functionally cooperate to activate the utrophin promoter.

    Gyrd-Hansen, Mads, Krag, T. O. B., Rosmarin, A. G. & Khurana, T. S., 2002, In: Journal of the Neurological Sciences. 197, 1-2, p. 27-35 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  22. All roads lead to ubiquitin

    Gyrd-Hansen, Mads, 2017, In: Cell Death and Differentiation. 24, 7, p. 1135-1136 2 p.

    Research output: Contribution to journal › Editorial › Research

  23. Published

    IAPs: from caspase inhibitors to modulators of NF-kappaB, inflammation and cancer

    Gyrd-Hansen, Mads & Meier, P., 2010, In: Nature Reviews. Cancer. 10, 8, p. 561-74 13 p.

    Research output: Contribution to journal › Review › Research › peer-review

  24. Heat shock protein 70 promotes cancer cell viability by safeguarding lysosomal integrity.

    Gyrd-Hansen, Mads, Nylandsted, J. & Jäättelä, M., 2004, In: Cell Cycle. 3, 12, p. 1484-5 1 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  25. Cell scientist to watch - Mads Gyrd-Hansen

    Gyrd-Hansen, Mads, 2017, In: Journal of Cell Science. 130, 12, p. 1981-1983 3 p.

    Research output: Contribution to journal › Comment/debate › Research

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