Daniel Hargbøl Madsen

Daniel Hargbøl Madsen

Associate Professor


Publication year:
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1 - 28 out of 28Page size: 100
  1. 2023
  2. Published

    Ambra1 modulates the tumor immune microenvironment and response to PD-1 blockade in melanoma

    Frias, A., Di Leo, L., Antoranz, A., Nazerai, L., Carretta, M., Bodemeyer, V., Pagliuca, C., Dahl, C., Claps, G., Mandelli, G. E., Andhari, M. D., Pacheco, M. P., Sauter, T., Robert, C., Guldberg, P., Madsen, Daniel Hargbøl, Cecconi, F., Bosisio, F. M. & de Zio, Daniela, 2023, In: Journal for ImmunoTherapy of Cancer. 11, 3, 15 p., e006389.

    Research output: Contribution to journal › Journal article › Research › peer-review

  3. Published

    Plasma YKL-40 is associated with prognosis in patients with metastatic pancreatic cancer receiving immune checkpoint inhibitors in combination with radiotherapy

    Johansen, A. Z., Novitski, Sif Ingibergsdóttir, Hjaltelin, Jessica Xin, Theile, S., Boisen, M. K., Brunak, Søren, Madsen, Daniel Hargbøl, Nielsen, Dorte Lisbet & Chen, I. M., 2023, In: Frontiers in Immunology. 14, 10 p., 1228907.

    Research output: Contribution to journal › Journal article › Research › peer-review

  4. 2022
  5. Published

    ADAM17-mediated EGFR ligand shedding directs macrophage promoted cancer cell invasion

    Gnosa, S., Puig Blasco, Laia, Piotrowski, Kris, Freiberg, M. L., Savickas, S., Madsen, Daniel Hargbøl, Keller, U. A. D., Kronqvist, P. & Kveiborg, Marie, 2022, In: JCI insight. 7, 18, 21 p., e155296.

    Research output: Contribution to journal › Journal article › Research › peer-review

  6. Published

    Arginase-2-specific cytotoxic T cells specifically recognize functional regulatory T cells

    Weis-Banke, S. E., Lisle, T. L., Perez Penco, Maria, Schina, A., Hübbe, M. L., Siersbæk, M., Holmström, M. O., Jørgensen, M. A., Svane, Inge Marie, Met, Özcan, Ødum, Niels, Madsen, Daniel Hargbøl, dqp123, dqp123, Grøntved, L. & Andersen, Mads Hald, 2022, In: Journal for ImmunoTherapy of Cancer. 10, 10, e005326.

    Research output: Contribution to journal › Journal article › Research › peer-review

  7. Published

    Blockade of beta-adrenergic receptors reduces cancer growth and enhances the response to anti-CTLA4 therapy by modulating the tumor microenvironment

    Fjæstad, K. Y., Rømer, A. M. A., Goitea, V., Johansen, A. Z., Thorseth, M. L., Carretta, M., Engelholm, Lars Henning, Grøntved, L., Junker, N. & Madsen, Daniel Hargbøl, 2022, In: Oncogene. 41, p. 1364-1375

    Research output: Contribution to journal › Journal article › Research › peer-review

  8. Published

    Chitooligosaccharides Improve the Efficacy of Checkpoint Inhibitors in a Mouse Model of Lung Cancer

    Johansen, A. Z., Carretta, M., Thorseth, M. L., Khan, S., Fjæstad, K. Y., Brøchner, Christian Beltoft, Linder, H., Ankjærgaard, C., dqp123, dqp123, Chen, I., Nielsen, Dorte Lisbet, Behrens, C. P. & Madsen, Daniel Hargbøl, 2022, In: Pharmaceutics. 14, 5, 1046.

    Research output: Contribution to journal › Journal article › Research › peer-review

  9. Published

    Fibrotic activity quantified in serum by measurements of type III collagen pro-peptides can be used for prognosis across different solid tumor types

    Willumsen, N., Jensen, C., Green, G., Nissen, N. I., Neely, J., Nelson, D. M., Pedersen, R. S., Frederiksen, P., Chen, I. M., Boisen, M. K., Johansen, A. Z., Madsen, D. H., Svane, I. M., Lipton, A., Leitzel, K., Ali, S. M., Erler, J. T., Hurkmans, D. P., Mathijssen, R. H. J., Aerts, J. & 5 others, Eslam, M., George, J., Christiansen, C., Bissel, M. J. & Karsdal, M. A., 2022, In: Cellular and Molecular Life Sciences. 79, 4, 11 p., 204.

    Research output: Contribution to journal › Review › Research › peer-review

  10. Published

    Peptide vaccination activating Galectin-3-specific T cells offers a novel means to target Galectin-3-expressing cells in the tumor microenvironment

    Bendtsen, S. K., Perez Penco, Maria, Hübbe, M. L., Martinenaite, E., Orebo Holmström, M., Weis-Banke, S. E., Grønne Dahlager Jørgensen, N., Jørgensen, M. A., Munir Ahmad, S., Jensen, K. M., Friese, C., Lundsager, M. T., Johansen, A. Z., Carretta, M., Ødum, Niels, Met, Özcan, Svane, Inge Marie, Madsen, Daniel Hargbøl & Andersen, Mads Hald, 2022, In: OncoImmunology. 11, 1, 2026020.

    Research output: Contribution to journal › Journal article › Research › peer-review

  11. Published

    TGFβ-derived immune modulatory vaccine: targeting the immunosuppressive and fibrotic tumor microenvironment in a murine model of pancreatic cancer

    Perez Penco, Maria, Weis-Banke, S. E., Schina, A., Siersbæk, M., Hübbe, M. L., Jørgensen, M. A., Lecoq, I., Lara De La Torre, L., Bendtsen, S. K., Martinenaite, E., Holmström, M. O., Madsen, Daniel Hargbøl, dqp123, dqp123, Ødum, Niels, Grøntved, L. & Andersen, Mads Hald, 2022, In: Journal for ImmunoTherapy of Cancer. 10, 12, 15 p., e005491.

    Research output: Contribution to journal › Journal article › Research › peer-review

  12. Published

    Uncovering mediators of collagen degradation in the tumor microenvironment

    Thorseth, M. L., Carretta, M., Jensen, C., Mølgaard, K., Jürgensen, Henrik Jessen, Engelholm, Lars Henning, Behrendt, Niels, Willumsen, N. & Madsen, Daniel Hargbøl, 2022, In: Matrix Biology Plus. 13, 100101.

    Research output: Contribution to journal › Journal article › Research › peer-review

  13. 2021
  14. Published

    Arginase 1–Based immune modulatory vaccines induce anticancer immunity and synergize with Anti–PD-1 checkpoint blockade

    Jørgensen, M. A., Ugel, S., Hübbe, M. L., Carretta, M., Perez Penco, Maria, Weis-Banke, S. E., Martinenaite, E., Kopp, K., Chapellier, M., Adamo, A., de Sanctis, F., Frusteri, C., Iezzi, M., Zocca, M. B., Madsen, Daniel Hargbøl, Pedersen, A. W., Bronte, V. & Andersen, Mads Hald, 2021, In: Cancer Immunology Research. 9, 11, p. 1316-1326 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  15. Published

    Immune Modulatory Properties of Collagen in Cancer

    Rømer, A. M. A., Thorseth, M. L. & Madsen, Daniel Hargbøl, 2021, In: Frontiers in Immunology. 12, 791453.

    Research output: Contribution to journal › Review › Research › peer-review

  16. 2019
  17. Published

    Immune regulation by fibroblasts in tissue injury depends on uPARAP-mediated uptake of collectins

    Jürgensen, Henrik Jessen, Nørregaard, Kirstine Sandal, Sibree, M. M., Santoni Rugiu, Eric, Madsen, Daniel Hargbøl, Wassilew, K., Krustrup, D., Garred, Peter, Bugge, T. H., Engelholm, Lars Henning & Behrendt, Niels, 1 Jan 2019, In: Journal of Cell Biology. 218, 1, p. 333-349 17 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  18. Published

    Assessment of extracellular matrix and tissue derived metabolites in a liquid biopsy for identifying endotypes of metastatic melanoma patients with differential response to immune checkpoint inhibitor treatment.

    Willumsen, N., Bager, C. L., Jensen, C., Karsdal, M. A., Madsen, Daniel Hargbøl, Hansen, M., Schmidt, H. & Svane, Inge Marie, 2019, In: Journal of Clinical Oncology. 37, 15_suppl, e14050.

    Research output: Contribution to journal › Conference abstract in journal › Research › peer-review

  19. 2017
  20. Published

    Tumor-Associated Macrophages Derived from Circulating Inflammatory Monocytes Degrade Collagen through Cellular Uptake

    Madsen, Daniel Hargbøl, Jürgensen, Henrik Jessen, Siersbæk, M. S., Kuczek, D. E., Grey Cloud, L., Liu, S., Behrendt, Niels, Grøntved, L., Weigert, R. & Bugge, T. H., 26 Dec 2017, In: Cell Reports. 21, 13, p. 3662-3671 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  21. 2016
  22. Published

    A CCR2 macrophage endocytic pathway mediates extravascular fibrin clearance in vivo

    Motley, M. P., Madsen, Daniel Hargbøl, Jürgensen, Henrik Jessen, Spencer, D. E., Szabo, R., Holmbeck, Kenn, Flick, M. J., Lawrence, D. A., Castellino, F. J., Weigert, R. & Bugge, T. H., 2016, In: Blood. 127, 9, p. 1085-1096 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  23. 2015
  24. Published

    The collagen receptor uPARAP/Endo180 in tissue degradation and cancer (Review)

    Carlsen Melander, E. M., Jürgensen, Henrik Jessen, Madsen, Daniel Hargbøl, Engelholm, Lars Henning & Behrendt, Niels, Oct 2015, In: International Journal of Oncology. 47, 4, p. 1177-88 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  25. 2013
  26. Published

    M2-like macrophages are responsible for collagen degradation through a mannose receptor-mediated pathway

    Madsen, Daniel Hargbøl, Leonard, D., Masedunskas, A., Moyer, A., Jürgensen, Henrik Jessen, Peters, D. E., Amornphimoltham, P., Selvaraj, A., Yamada, S. S., Brenner, D. A., Burgdorf, S., Engelholm, Lars Henning, Behrendt, Niels, Holmbeck, K., Weigert, R. & Bugge, T. H., 16 Sep 2013, In: Journal of Cell Biology. 202, 6, p. 951-66 16 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  27. Published

    Targeting a single function of the multifunctional matrix metalloprotease MT1-MMP: impact on lymphangiogenesis

    Ingvarsen, S., Porse, A., Erpicum, C., Maertens, L., Jürgensen, H. J., Madsen, Daniel Hargbøl, Melander, M. C., Gårdsvoll, Henrik, Høyer-Hansen, G., Noel, A., Holmbeck, K., Engelholm, Lars Henning & Behrendt, Niels, 12 Apr 2013, In: Journal of Biological Chemistry. 288, 15, p. 10195-204 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  28. Published

    Differential actions of the endocytic collagen receptor uPARAP/Endo180 and the collagenase MMP-2 in bone homeostasis

    Madsen, Daniel Hargbøl, Jürgensen, Henrik Jessen, Ingvarsen, S., Melander, M. C., Albrechtsen, Reidar, Hald, A., Holmbeck, K., Bugge, T. H., Behrendt, Niels & Engelholm, Lars Henning, 2013, In: PloS one. 8, 8, p. e71261

    Research output: Contribution to journal › Journal article › Research › peer-review

  29. 2012
  30. Published

    Inhibitory Monoclonal Antibodies against Mouse Proteases Raised in Gene-Deficient Mice Block Proteolytic Functions in vivo

    Lund, I. K., Rasch, M. G., Ingvarsen, S., Pass, J., Madsen, Daniel Hargbøl, Engelholm, Lars Henning, Behrendt, Niels & Høyer-Hansen, G., 2012, In: Frontiers in Pharmacology. 3, p. 122

    Research output: Contribution to journal › Journal article › Research › peer-review

  31. 2011
  32. Published

    The endocytic receptor uPARAP/Endo180 in collagen turnover and its importance in physiological and pathological processes

    Madsen, Daniel Hargbøl, 30 Sep 2011

    Research output: Book/Report › Ph.D. thesis › Research

  33. Published

    The non-phagocytic route of collagen uptake: a distinct degradation pathway

    Madsen, Daniel Hargbøl, Ingvarsen, S., Jürgensen, Henrik Jessen, Melander, M. C., Kjøller, L., Moyer, A., Honoré, C., Madsen, M. C., Garred, Peter, Burgdorf, S., Bugge, T. H., Behrendt, Niels & Engelholm, Lars Henning, 29 Jul 2011, In: The Journal of Biological Chemistry. 286, 30, p. 26996-7010 15 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  34. Published

    A novel functional role of collagen glycosylation: interaction with the endocytic collagen receptor uPARAP/ENDO 180

    Jürgensen, Henrik Jessen, Madsen, Daniel Hargbøl, Ingvarsen, S., Melander, M. C., Gårdsvoll, Henrik, Patthy, L., Engelholm, Lars Henning & Behrendt, Niels, 2011, In: Journal of Biological Chemistry. 286, 37, p. 32736-48 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  35. 2009
  36. Published

    The collagen receptor uPARAP/Endo180

    Engelholm, Lars Henning, Ingvarsen, S., Jürgensen, Henrik Jessen, Hillig, T., Madsen, Daniel Hargbøl, Nielsen, B. S. & Behrendt, Niels, 1 Jan 2009, In: Frontiers in Bioscience. 14, p. 2103-14 12 p.

    Research output: Contribution to journal › Review › Research › peer-review

  37. 2008
  38. Published

    A composite role of vitronectin and urokinase in the modulation of cell morphology upon expression of the urokinase receptor

    Hillig, T., Engelholm, Lars Henning, Ingvarsen, S., Madsen, Daniel Hargbøl, Gårdsvoll, Henrik, Larsen, J. K., Ploug, Michael, Danø, K., Kjøller, L. & Behrendt, Niels, 30 May 2008, In: Journal of Biological Chemistry. 283, 22, p. 15217-15223 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  39. 2007

  40. Extracellular collagenases and the endocytic receptor, urokinase plasminogen activator receptor-associated protein/Endo180, cooperate in fibroblast-mediated collagen degradation

    Madsen, Daniel Hargbøl, Engelholm, Lars Henning, Ingvarsen, S., Hillig, T., Wagenaar-Miller, R. A., Kjøller, L., Gårdsvoll, Henrik, Høyer-Hansen, G., Holmbeck, Kenn, Bugge, T. H. & Behrendt, Niels, 14 Sep 2007, In: The Journal of Biological Chemistry. 282, 37, p. 27037-45 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  41. Published

    Increased expression of the collagen internalization receptor uPARAP/Endo180 in the stroma of head and neck cancer

    Sulek, J., Wagenaar-Miller, R. A., Shireman, J., Molinolo, A., Madsen, Daniel Hargbøl, Engelholm, Lars Henning, Behrendt, Niels & Bugge, T. H., Apr 2007, In: Journal of Histochemistry and Cytochemistry. 55, 4, p. 347-53 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

ID: 22311148