PhD Course: Mechanisms in Innate Immune Signaling
Are you a PhD student interested in gaining a better understanding of innate immune responses and host-pathogen interactions? Then apply now for SIC’s PhD course and get a unique opportunity to interact with students and faculty at the SIC headquarters in Copenhagen.
About the course
The primary objective of this PhD course is to enable participants to gain comprehensive knowledge of induced innate immune responses, both to microbes (commensals and pathogens) and in inflammatory conditions within the skin and mucosa. Focus is on understanding the molecular mechanisms that govern these early immune responses and on the post-translational modifications that take place. It explores how these modifications can be regulated and the potential consequences of their deregulation. Moreover, the course will feature presentations on pharmacological interventions designed to address deregulated immune responses.
The course includes a journal club, where students present pre-selected research papers to one another, and meet-the-speaker sessions, which provide opportunities for students to interact with the invited speakers of the course.
Throughout the course, participants will benefit from lectures delivered by leading national and international researchers within the fields immune signaling both from SIC, from Danish research institutions and internationally.
Learning objectives
A student who has met the objectives of the course will be able to:
Explain concepts governing activation of innate immune responses
- Describe signaling pathways and post-translation modifications involved in immune signaling
- Have examples of how deregulation of innate immune signaling can lead to disease
- Explain the interplay between the host and microbes
- Discuss techniques for addressing outstanding questions in the field and address their strengths and weaknesses
Speakers and themes:
- Professor William Agace (DTU): immune cells and signaling in the gut
- Associate Professor Beatrice Dyring-Andersen (SIC/CPR, UCPH): proteomics in inflammatory skin disorders
- Assistant Professor Ieva Bagdonaite (UCPH): Glycans in host-viral interactions
- Associate Professor Mariena van der Plas (LFCCDD, UCPH): Pharma interventions in infection/inflammation
- Dr. Professor Philipp Henneke, University of Freiburg works on development of cellular innate immunity: site-specific differentiation and adaptation of tissue macrophages throughout life
- Dr. Charlotte Odendall, King’s College London works on host/bacteria interactions, in particular at the level of type I and III interferons.
Assistant Professor Berthe Katrine Fiil and Professor Mads Gyrd-Hansen will do a range of lectures on innate immune signaling, regulation of immunogenic cell cell death, post-translational modifications in innate immune signaling and host-pathogen interactions.