28 September 2020

Fabulous Facility: Watch Individual Cells in their Microenvironment

Single-cell sequencing

The LEO Foundation has granted DKK 15 million for single-cell sequencing apparatus which can show cell populations and cell functions at single-cell level. All researchers can book it as part of Core Facility for Flow Cytometry & Single Cell Analysis.

​​The LEO Foundation Skin Immunology Research Center (SIC) is the recipient of the equipment grant.

Single-cell sequencing is believed to be capable of revolutionising cell biology research – especially within immunology, cybernetics, inflammation and cancer. Single-cell sequencing makes it possible to follow the individual cell's development up close and to understand the complex interactions as well as the individual cell's role while the immune system is at work.

The new apparatus is part of SUND's Core Facility for Flow Cytometry and Single Cell Analysis (the last part of the name is an extension introduced on account of the equipment) at the Department of Immunology and Microbiology. The facility is based on the 14th floor of the Maersk Tower and headed by Professor Jan Pravsgaard Christensen.

VIDEO: About single cell sequencing.

'The new equipment enables us to offer the entire package for understanding cells' reactions to each other and to diseases. Flow cytometry makes it possible to analyse populations of thousands or millions of cells and to zoom in on a particular type of cell. Single-cell sequencing takes a step further and analyses the individual molecules inside a cell. This will make a huge difference', says Jan Pravsgaard Christensen.

All researchers at the faculty as well as external researchers can, for payment, book and use the equipment under the competent supervision of Specialist Operator Rasmus Nielsen Klitgaard. He was employed by the core facility with the grant to support the new instruments.


Learn more about single-cell sequencing and how it is used in research at the LEO Foundation Skin Immunology Research Center.

The new equipment for single-cell sequencing includes:

  • ImageStream
  • 10X System
  • MiSeq
  • NovaSeq
  • Various support equipment


Read more about the Core Facility for Flow Cytometry and Single Cell Analysis

Read more about the LEO Foundation Skin Immunology Research Center

Read about the core facilities at UCPH